ITMI911470A0 - N-(5-tioxo-l-prolil)-l-cisteina e suoi derivati, loro preparazione ed impiego terapeutico - Google Patents
N-(5-tioxo-l-prolil)-l-cisteina e suoi derivati, loro preparazione ed impiego terapeuticoInfo
- Publication number
- ITMI911470A0 ITMI911470A0 IT91MI1470A ITMI911470A ITMI911470A0 IT MI911470 A0 ITMI911470 A0 IT MI911470A0 IT 91MI1470 A IT91MI1470 A IT 91MI1470A IT MI911470 A ITMI911470 A IT MI911470A IT MI911470 A0 ITMI911470 A0 IT MI911470A0
- Authority
- IT
- Italy
- Prior art keywords
- prolyl
- thioxo
- cysteine
- derivatives
- preparation
- Prior art date
Links
- GRRYKTAZNOFTOA-WHFBIAKZSA-N (2r)-3-sulfanyl-2-[[(2s)-5-sulfanylidenepyrrolidine-2-carbonyl]amino]propanoic acid Chemical compound OC(=O)[C@H](CS)NC(=O)[C@@H]1CCC(=S)N1 GRRYKTAZNOFTOA-WHFBIAKZSA-N 0.000 title 1
- 108010084118 N-(5-thioxo-L-prolyl)-L-cysteine Proteins 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic
- C07K5/06173—Dipeptides with the first amino acid being heterocyclic and Glp-amino acid; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pyrrole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITMI911470A IT1249650B (it) | 1991-05-29 | 1991-05-29 | N-(5-tioxo-l-prolil)-l-cisteina e suoi derivati, loro preparazione ed impiego terapeutico |
US07/879,907 US5254579A (en) | 1991-05-29 | 1992-05-08 | N-(5-thioxo-L-prolyl)-L-cysteine, derivatives thereof, processes for the preparation thereof and pharmaceutical compositions containing them |
EP19920108659 EP0515995A3 (en) | 1991-05-29 | 1992-05-22 | N-(5-thioxo-l-prolyl)-l-cysteine, derivatives thereof, processes for the preparation thereof and pharmaceutical compositions containing them |
DE199292108659T DE515995T1 (de) | 1991-05-29 | 1992-05-22 | N-(5-thioxo-l-propyl)-l-cystein und derivate, deren herstellung und diese verbindungen enthaltende pharmazeutische zusammensetzungen. |
ES92108659T ES2052484T1 (es) | 1991-05-29 | 1992-05-22 | N-(5-tioxo-l-prolil)-l-cisteina, sus derivados, procedimientos para su preparacion y composiciones farmaceuticas que los contienen. |
GR930300007T GR930300007T1 (it) | 1991-05-29 | 1993-04-28 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITMI911470A IT1249650B (it) | 1991-05-29 | 1991-05-29 | N-(5-tioxo-l-prolil)-l-cisteina e suoi derivati, loro preparazione ed impiego terapeutico |
Publications (3)
Publication Number | Publication Date |
---|---|
ITMI911470A0 true ITMI911470A0 (it) | 1991-05-29 |
ITMI911470A1 ITMI911470A1 (it) | 1992-11-29 |
IT1249650B IT1249650B (it) | 1995-03-09 |
Family
ID=11360007
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ITMI911470A IT1249650B (it) | 1991-05-29 | 1991-05-29 | N-(5-tioxo-l-prolil)-l-cisteina e suoi derivati, loro preparazione ed impiego terapeutico |
Country Status (6)
Country | Link |
---|---|
US (1) | US5254579A (it) |
EP (1) | EP0515995A3 (it) |
DE (1) | DE515995T1 (it) |
ES (1) | ES2052484T1 (it) |
GR (1) | GR930300007T1 (it) |
IT (1) | IT1249650B (it) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL98310A (en) * | 1990-06-08 | 1996-08-04 | Astra Ab | Medicinal preparations containing a history of cystine |
IT1256178B (it) * | 1992-11-30 | 1995-11-29 | Lorenzo Ferrari | Composti ad attivita' terapeutica utili per il trattamento di malattieconnesse ad una carenza di glutatione, procedimento per la loro preparazione e composizioni farmaceutiche che li contengono. |
SE9500897D0 (sv) * | 1995-03-14 | 1995-03-14 | Astra Ab | The pharmacological use of certain cystine derivatives |
WO1997017959A1 (en) * | 1995-11-13 | 1997-05-22 | Smithkline Beecham Corporation | Hemoregulatory compounds |
WO1997017851A1 (en) * | 1995-11-13 | 1997-05-22 | Smithkline Beecham Corporation | Hemoregulatory compounds |
SE9901573D0 (sv) | 1999-05-03 | 1999-05-03 | Astra Ab | New compounds |
AR023819A1 (es) | 1999-05-03 | 2002-09-04 | Astrazeneca Ab | FORMULACIoN FARMACEUTICA, KIT DE PARTES Y UTILIZACION DE DICHA FORMULACION |
EP1360965A4 (en) * | 2001-02-16 | 2009-07-29 | Asubio Pharma Co Ltd | METHOD FOR THE TREATMENT OF DISEASES ASSOCIATED WITH A DECREASE OF THE EXPOSURE OF THE AOP-1 GENE OR AOP-1 AND MEANS FOR THE TREATMENT OF THE DISEASES |
US6523346B1 (en) | 2001-11-02 | 2003-02-25 | Alstom (Switzerland) Ltd | Process for controlling the cooling air mass flow of a gas turbine set |
US6640550B2 (en) | 2001-11-02 | 2003-11-04 | Alstom (Switzerland) Ltd | Gas turbo-group with cooling air system |
US6644012B2 (en) | 2001-11-02 | 2003-11-11 | Alston (Switzerland) Ltd | Gas turbine set |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HUT40447A (en) * | 1984-03-29 | 1986-12-28 | Sandoz Ag | Process for preparing substituted alpha-amino acids and pharmaceutical compositions containing such compounds |
IT1216096B (it) * | 1988-03-15 | 1990-02-22 | Farmaceutica Italiana S P A S | L_piroglutamil_l_cisteina, dipeptide ad elevata attivita'anticatarattogena e composizioni farmaceutiche che lo contengono. |
-
1991
- 1991-05-29 IT ITMI911470A patent/IT1249650B/it active IP Right Grant
-
1992
- 1992-05-08 US US07/879,907 patent/US5254579A/en not_active Expired - Lifetime
- 1992-05-22 DE DE199292108659T patent/DE515995T1/de active Pending
- 1992-05-22 ES ES92108659T patent/ES2052484T1/es active Pending
- 1992-05-22 EP EP19920108659 patent/EP0515995A3/en not_active Withdrawn
-
1993
- 1993-04-28 GR GR930300007T patent/GR930300007T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
DE515995T1 (de) | 1993-04-08 |
ES2052484T1 (es) | 1994-07-16 |
IT1249650B (it) | 1995-03-09 |
EP0515995A3 (en) | 1993-07-21 |
EP0515995A2 (en) | 1992-12-02 |
ITMI911470A1 (it) | 1992-11-29 |
US5254579A (en) | 1993-10-19 |
GR930300007T1 (it) | 1993-04-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
0001 | Granted | ||
TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19970529 |