ITMI911470A1 - N-(5-tioxo-l-prolil)-l-cisteina e suoi derivati, loro preparazione ed impiego terapeutico - Google Patents

N-(5-tioxo-l-prolil)-l-cisteina e suoi derivati, loro preparazione ed impiego terapeutico

Info

Publication number
ITMI911470A1
ITMI911470A1 IT001470A ITMI911470A ITMI911470A1 IT MI911470 A1 ITMI911470 A1 IT MI911470A1 IT 001470 A IT001470 A IT 001470A IT MI911470 A ITMI911470 A IT MI911470A IT MI911470 A1 ITMI911470 A1 IT MI911470A1
Authority
IT
Italy
Prior art keywords
cistein
prolil
tioxo
derivatives
preparation
Prior art date
Application number
IT001470A
Other languages
English (en)
Inventor
Germano Coppi
Stefano Poli
Giovanni Signorelli
Original Assignee
Poli Ind Chimica Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Poli Ind Chimica Spa filed Critical Poli Ind Chimica Spa
Priority to ITMI911470A priority Critical patent/IT1249650B/it
Publication of ITMI911470A0 publication Critical patent/ITMI911470A0/it
Priority to US07/879,907 priority patent/US5254579A/en
Priority to ES92108659T priority patent/ES2052484T1/es
Priority to EP19920108659 priority patent/EP0515995A3/en
Priority to DE199292108659T priority patent/DE515995T1/de
Publication of ITMI911470A1 publication Critical patent/ITMI911470A1/it
Priority to GR930300007T priority patent/GR930300007T1/el
Application granted granted Critical
Publication of IT1249650B publication Critical patent/IT1249650B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic
    • C07K5/06173—Dipeptides with the first amino acid being heterocyclic and Glp-amino acid; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ITMI911470A 1991-05-29 1991-05-29 N-(5-tioxo-l-prolil)-l-cisteina e suoi derivati, loro preparazione ed impiego terapeutico IT1249650B (it)

Priority Applications (6)

Application Number Priority Date Filing Date Title
ITMI911470A IT1249650B (it) 1991-05-29 1991-05-29 N-(5-tioxo-l-prolil)-l-cisteina e suoi derivati, loro preparazione ed impiego terapeutico
US07/879,907 US5254579A (en) 1991-05-29 1992-05-08 N-(5-thioxo-L-prolyl)-L-cysteine, derivatives thereof, processes for the preparation thereof and pharmaceutical compositions containing them
ES92108659T ES2052484T1 (es) 1991-05-29 1992-05-22 N-(5-tioxo-l-prolil)-l-cisteina, sus derivados, procedimientos para su preparacion y composiciones farmaceuticas que los contienen.
EP19920108659 EP0515995A3 (en) 1991-05-29 1992-05-22 N-(5-thioxo-l-prolyl)-l-cysteine, derivatives thereof, processes for the preparation thereof and pharmaceutical compositions containing them
DE199292108659T DE515995T1 (de) 1991-05-29 1992-05-22 N-(5-thioxo-l-propyl)-l-cystein und derivate, deren herstellung und diese verbindungen enthaltende pharmazeutische zusammensetzungen.
GR930300007T GR930300007T1 (it) 1991-05-29 1993-04-28

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI911470A IT1249650B (it) 1991-05-29 1991-05-29 N-(5-tioxo-l-prolil)-l-cisteina e suoi derivati, loro preparazione ed impiego terapeutico

Publications (3)

Publication Number Publication Date
ITMI911470A0 ITMI911470A0 (it) 1991-05-29
ITMI911470A1 true ITMI911470A1 (it) 1992-11-29
IT1249650B IT1249650B (it) 1995-03-09

Family

ID=11360007

Family Applications (1)

Application Number Title Priority Date Filing Date
ITMI911470A IT1249650B (it) 1991-05-29 1991-05-29 N-(5-tioxo-l-prolil)-l-cisteina e suoi derivati, loro preparazione ed impiego terapeutico

Country Status (6)

Country Link
US (1) US5254579A (it)
EP (1) EP0515995A3 (it)
DE (1) DE515995T1 (it)
ES (1) ES2052484T1 (it)
GR (1) GR930300007T1 (it)
IT (1) IT1249650B (it)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL98310A (en) * 1990-06-08 1996-08-04 Astra Ab Medicinal preparations containing a history of cystine
IT1256178B (it) * 1992-11-30 1995-11-29 Lorenzo Ferrari Composti ad attivita' terapeutica utili per il trattamento di malattieconnesse ad una carenza di glutatione, procedimento per la loro preparazione e composizioni farmaceutiche che li contengono.
SE9500897D0 (sv) * 1995-03-14 1995-03-14 Astra Ab The pharmacological use of certain cystine derivatives
JP2000501385A (ja) * 1995-11-13 2000-02-08 スミスクライン・ビーチャム・コーポレイション 血液調節化合物
US6051584A (en) * 1995-11-13 2000-04-18 Smithkline Beecham Corporation Hemoregulatory compounds
AR023819A1 (es) 1999-05-03 2002-09-04 Astrazeneca Ab FORMULACIoN FARMACEUTICA, KIT DE PARTES Y UTILIZACION DE DICHA FORMULACION
SE9901573D0 (sv) 1999-05-03 1999-05-03 Astra Ab New compounds
AU2002233643B2 (en) 2001-02-16 2007-07-26 Asubio Pharma Co., Ltd. Methods of treating diseases in association with decrease in the expression of AOP-1 gene or AOP-1 and remedies for the diseases
US6644012B2 (en) 2001-11-02 2003-11-11 Alston (Switzerland) Ltd Gas turbine set
US6523346B1 (en) 2001-11-02 2003-02-25 Alstom (Switzerland) Ltd Process for controlling the cooling air mass flow of a gas turbine set
US6640550B2 (en) 2001-11-02 2003-11-04 Alstom (Switzerland) Ltd Gas turbo-group with cooling air system

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUT40447A (en) * 1984-03-29 1986-12-28 Sandoz Ag Process for preparing substituted alpha-amino acids and pharmaceutical compositions containing such compounds
IT1216096B (it) * 1988-03-15 1990-02-22 Farmaceutica Italiana S P A S L_piroglutamil_l_cisteina, dipeptide ad elevata attivita'anticatarattogena e composizioni farmaceutiche che lo contengono.

Also Published As

Publication number Publication date
EP0515995A3 (en) 1993-07-21
IT1249650B (it) 1995-03-09
US5254579A (en) 1993-10-19
EP0515995A2 (en) 1992-12-02
ES2052484T1 (es) 1994-07-16
GR930300007T1 (it) 1993-04-28
DE515995T1 (de) 1993-04-08
ITMI911470A0 (it) 1991-05-29

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Legal Events

Date Code Title Description
0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19970529