IT1219542B - Derivati pepticidi,loro preparazione e loro impiego come medicamenti - Google Patents

Derivati pepticidi,loro preparazione e loro impiego come medicamenti

Info

Publication number
IT1219542B
IT1219542B IT47871/88A IT4787188A IT1219542B IT 1219542 B IT1219542 B IT 1219542B IT 47871/88 A IT47871/88 A IT 47871/88A IT 4787188 A IT4787188 A IT 4787188A IT 1219542 B IT1219542 B IT 1219542B
Authority
IT
Italy
Prior art keywords
pepticidal
medications
derivatives
preparation
pepticidal derivatives
Prior art date
Application number
IT47871/88A
Other languages
English (en)
Other versions
IT8847871A0 (it
Inventor
Beat Weidmann
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of IT8847871A0 publication Critical patent/IT8847871A0/it
Application granted granted Critical
Publication of IT1219542B publication Critical patent/IT1219542B/it

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0207Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)4-C(=0), e.g. 'isosters', replacing two amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36Radicals substituted by singly-bound nitrogen atoms
    • C07D213/40Acylated substituent nitrogen atom
IT47871/88A 1987-04-23 1988-04-20 Derivati pepticidi,loro preparazione e loro impiego come medicamenti IT1219542B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3713613 1987-04-23

Publications (2)

Publication Number Publication Date
IT8847871A0 IT8847871A0 (it) 1988-04-20
IT1219542B true IT1219542B (it) 1990-05-18

Family

ID=6326146

Family Applications (1)

Application Number Title Priority Date Filing Date
IT47871/88A IT1219542B (it) 1987-04-23 1988-04-20 Derivati pepticidi,loro preparazione e loro impiego come medicamenti

Country Status (6)

Country Link
JP (1) JPS63295541A (it)
BE (1) BE1002213A5 (it)
CH (1) CH676003A5 (it)
FR (1) FR2614533A1 (it)
GB (1) GB2203740B (it)
IT (1) IT1219542B (it)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL90872A0 (en) * 1988-07-08 1990-02-09 Smithkline Beckman Corp Retroviral protease binding peptides
EP0357332A3 (en) * 1988-08-24 1991-07-31 Merck & Co. Inc. Renin inhibitors useful for the treatment of aids by inhibition of hiv protease
EP0374097A3 (de) * 1988-12-15 1991-06-12 Ciba-Geigy Ag Verwendung von Peptidisosteren als retrovirale Proteasehemmer
DE3912829A1 (de) * 1989-04-19 1990-10-25 Bayer Ag Verwendung von renininhibitorischen peptiden als mittel gegen retroviren
US5212157A (en) * 1989-06-06 1993-05-18 Bio-Mega, Inc. Enzyme inhibitors
US5126326A (en) * 1989-06-06 1992-06-30 Bio-Mega, Inc. Enzyme inhibiting peptide derivatives
DE3941235A1 (de) * 1989-12-14 1991-06-20 Bayer Ag Neue peptide, ihre herstellung und ihre verwendung in arzneimitteln
DE4001236A1 (de) * 1990-01-18 1991-07-25 Bayer Ag Neue peptide, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel, insbesondere als arzneimittel gegen retroviren
US5071837A (en) * 1990-11-28 1991-12-10 Warner-Lambert Company Novel renin inhibiting peptides
NZ241099A (en) * 1991-01-02 1994-08-26 Merrell Dow Pharma Difluorostatone analogues and derivatives and pharmaceutical compositions
KR100220876B1 (ko) * 1991-01-02 1999-10-01 슈테펜엘.네스비트 항 바이러스 화합물
DE4126485A1 (de) * 1991-08-10 1993-02-11 Bayer Ag Trifluormethyl-haltige pseudopeptide
AU680009B2 (en) * 1993-07-08 1997-07-17 Aventisub Ii Inc. Difluoro statone analogs
JPH09502437A (ja) * 1993-09-09 1997-03-11 メレルファーマスーティカルズ インコーポレイテッド ジフルオロスタトン抗ウイルス類似体
US6114380A (en) * 1995-12-18 2000-09-05 Merrell Pharmaceuticals Inc. Difluoro statone analogs

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4665055A (en) * 1985-06-17 1987-05-12 Merck & Co., Inc. Peptide renin inhibitors
JPS63503380A (ja) * 1986-01-16 1988-12-08 アボット・ラボラトリーズ ペプチド類似体

Also Published As

Publication number Publication date
BE1002213A5 (fr) 1990-10-16
CH676003A5 (it) 1990-11-30
JPS63295541A (ja) 1988-12-01
GB2203740B (en) 1991-04-17
GB2203740A (en) 1988-10-26
GB8809228D0 (en) 1988-05-25
IT8847871A0 (it) 1988-04-20
FR2614533A1 (fr) 1988-11-04

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