CN102038671B - 包含左卡尼汀和羟苯磺酸盐的药物组合物 - Google Patents
包含左卡尼汀和羟苯磺酸盐的药物组合物 Download PDFInfo
- Publication number
- CN102038671B CN102038671B CN2010102159989A CN201010215998A CN102038671B CN 102038671 B CN102038671 B CN 102038671B CN 2010102159989 A CN2010102159989 A CN 2010102159989A CN 201010215998 A CN201010215998 A CN 201010215998A CN 102038671 B CN102038671 B CN 102038671B
- Authority
- CN
- China
- Prior art keywords
- salt
- levocarnitine
- benzene sulfonate
- pharmaceutical composition
- hydroxy benzene
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/095—Sulfur, selenium, or tellurium compounds, e.g. thiols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Abstract
Description
Claims (15)
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN2010102159989A CN102038671B (zh) | 2010-06-29 | 2010-06-29 | 包含左卡尼汀和羟苯磺酸盐的药物组合物 |
JP2013516977A JP2013529654A (ja) | 2010-06-29 | 2011-06-10 | レボカルニチン及びドベシレートを含む医薬組成物 |
PCT/CN2011/075570 WO2012000377A1 (zh) | 2010-06-29 | 2011-06-10 | 包含左卡尼汀和羟苯磺酸盐的药物组合物 |
US13/807,534 US20130172414A1 (en) | 2010-06-29 | 2011-06-10 | Pharmaceutical composition comprising levocarnitine and dobesilate |
EP11800122.1A EP2589382A4 (en) | 2010-06-29 | 2011-06-10 | PHARMACEUTICAL COMPOSITION CONTAINING LEVOCARNITINE AND DOBESILATE |
HK11106611.3A HK1152485A1 (en) | 2010-06-29 | 2011-06-28 | A pharmaceutical composition comprising l-carnitine and dobesilate |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN2010102159989A CN102038671B (zh) | 2010-06-29 | 2010-06-29 | 包含左卡尼汀和羟苯磺酸盐的药物组合物 |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201210244466.7A Division CN102727481B (zh) | 2010-06-29 | 2010-06-29 | 包含左卡尼汀和羟苯磺酸盐的药物组合物 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN102038671A CN102038671A (zh) | 2011-05-04 |
CN102038671B true CN102038671B (zh) | 2012-07-04 |
Family
ID=43905438
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN2010102159989A Expired - Fee Related CN102038671B (zh) | 2010-06-29 | 2010-06-29 | 包含左卡尼汀和羟苯磺酸盐的药物组合物 |
Country Status (6)
Country | Link |
---|---|
US (1) | US20130172414A1 (zh) |
EP (1) | EP2589382A4 (zh) |
JP (1) | JP2013529654A (zh) |
CN (1) | CN102038671B (zh) |
HK (1) | HK1152485A1 (zh) |
WO (1) | WO2012000377A1 (zh) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102038671B (zh) * | 2010-06-29 | 2012-07-04 | 辽宁思百得医药科技有限公司 | 包含左卡尼汀和羟苯磺酸盐的药物组合物 |
CN102911069A (zh) * | 2011-08-04 | 2013-02-06 | 广州市奥海生物科技有限公司 | 左旋肉碱柠檬酸钙及其制备方法与用途 |
CN102920690A (zh) * | 2011-08-12 | 2013-02-13 | 王康俊 | 一种治疗脑心血管疾患的化学药 |
CN102416006A (zh) * | 2011-12-05 | 2012-04-18 | 上海朝晖药业有限公司 | 一种羟苯磺酸钙胶囊及其制备方法 |
CN102512409A (zh) * | 2011-12-27 | 2012-06-27 | 辽宁思百得医药科技有限公司 | 包含左卡尼汀和羟苯磺酸盐的药物制剂及其制备方法 |
JP2016050206A (ja) * | 2014-08-29 | 2016-04-11 | 大塚製薬株式会社 | レボカルニチンを含有する医薬錠剤 |
CN104887645B (zh) * | 2015-06-15 | 2016-12-14 | 吉林万通药业集团梅河药业股份有限公司 | 阿莫西林胶囊及其制备方法 |
WO2020028684A1 (en) * | 2018-08-01 | 2020-02-06 | Jumpstart Fertility Pty Ltd | Salts of nicotinic acid and nicotinamide as anti-aging agents |
CN110123776A (zh) * | 2019-05-17 | 2019-08-16 | 贵州天安药业股份有限公司 | 一种高效微血管循环改善的羟苯磺酸钙胶囊 |
JP7366612B2 (ja) | 2019-07-09 | 2023-10-23 | 東和薬品株式会社 | レボカルニチンを含有する錠剤 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4513007A (en) * | 1983-05-03 | 1985-04-23 | Laboratoires Om Sa | Method for treating heart disease |
IT1277147B1 (it) * | 1995-01-20 | 1997-11-04 | Sigma Tau Ind Farmaceuti | Uso della carnitina e i suoi derivati per ridurre gli effetti tossici della ciclosporina-a e di altri farmaci immunosoppressivi. |
IT1306178B1 (it) * | 1999-07-27 | 2001-05-30 | Sigma Tau Ind Farmaceuti | Uso della l-carnitina e dei suoi alcanoil derivati per la preparazionedi un medicamento utile nel trattamento del paziente affetto da |
ES2208124B1 (es) * | 2002-11-29 | 2005-10-01 | Laboratorios Del Dr. Esteve, S.A. | Uso de los compuestos 2,5-dihidroxibencenosulfonicos para la fabricacion de un medicamento. |
US8647660B2 (en) * | 2004-12-29 | 2014-02-11 | Hill's Pet Nutrition, Inc. | Combination of limited nutrients and enhanced dietary antioxidants to impart improved kidney health |
WO2007022344A2 (en) * | 2005-08-17 | 2007-02-22 | Hill's Pet Nutrition, Inc. | Methods and compositions for the preventioin and treatment of kidney disease |
CN102038671B (zh) * | 2010-06-29 | 2012-07-04 | 辽宁思百得医药科技有限公司 | 包含左卡尼汀和羟苯磺酸盐的药物组合物 |
-
2010
- 2010-06-29 CN CN2010102159989A patent/CN102038671B/zh not_active Expired - Fee Related
-
2011
- 2011-06-10 US US13/807,534 patent/US20130172414A1/en not_active Abandoned
- 2011-06-10 EP EP11800122.1A patent/EP2589382A4/en not_active Withdrawn
- 2011-06-10 JP JP2013516977A patent/JP2013529654A/ja active Pending
- 2011-06-10 WO PCT/CN2011/075570 patent/WO2012000377A1/zh active Application Filing
- 2011-06-28 HK HK11106611.3A patent/HK1152485A1/xx not_active IP Right Cessation
Non-Patent Citations (3)
Title |
---|
丁峰 等.口服和静脉给予左卡尼汀治疗血液透析患者肉碱缺乏症的多中心随机对照研究.《上海医学》.2003,第26卷(第11期),785-788. * |
乔艳红 等.左卡尼汀与慢性肾衰竭.《长治医学院学报》.2008,第22卷(第2期),151-153. * |
吕永曼 等.羟苯磺酸钙治疗慢性肾功能衰竭的临床观察与实验研究.《华中科技大学学报(医学版》.2005,第34卷(第5期),554-557. * |
Also Published As
Publication number | Publication date |
---|---|
EP2589382A4 (en) | 2013-11-27 |
HK1152485A1 (en) | 2012-03-02 |
US20130172414A1 (en) | 2013-07-04 |
WO2012000377A1 (zh) | 2012-01-05 |
EP2589382A1 (en) | 2013-05-08 |
CN102038671A (zh) | 2011-05-04 |
JP2013529654A (ja) | 2013-07-22 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN102038671B (zh) | 包含左卡尼汀和羟苯磺酸盐的药物组合物 | |
CN102670864A (zh) | 治疗心脑血管疾病和糖尿病的抗氧化功能的药物组合物 | |
CN107441078A (zh) | 一种治疗糖尿病的药物组合物及其制备方法和用途 | |
CN101157692A (zh) | 小檗碱衍生物及其制备方法和其药物组合物与用途 | |
CN103304500A (zh) | 新型抗糖尿病化合物、其制备方法和用途 | |
CN107158025A (zh) | 一种含有羟基酪醇的降血脂组合物及其应用 | |
CN102727481B (zh) | 包含左卡尼汀和羟苯磺酸盐的药物组合物 | |
CN105395563A (zh) | 低聚古罗糖醛酸及其衍生物在制备预防和治疗高脂血症及其并发症的药物和保健品中的应用 | |
CN100357312C (zh) | 赖氨酸七叶皂苷及其制备方法和其用途 | |
CN100534998C (zh) | 果糖-1,6-二磷酸-钙盐的制备及其应用 | |
CN1695738B (zh) | 一种治疗高血压的药物组合物 | |
CN104856986A (zh) | 5-羟甲基糠醛在制备抗肝纤维化药物中的新用途 | |
CN101455753A (zh) | 一种减肥降脂中药制剂 | |
WO2022237731A1 (zh) | 一种治疗高脂血症的药物组合物及其制备方法 | |
CN102462772B (zh) | 胡黄连总苷提取物在制备用于预防和治疗脂肪肝药物中的用途 | |
RU2336076C2 (ru) | Пероральное лекарственное средство для восполнения дефицита магния в организме | |
CN1768760A (zh) | 一种含红花总黄酮药物组合物及其制备方法与用途 | |
CN103656012B (zh) | 一种治疗冠心病心绞痛的药物组合物的制备方法 | |
CN107184598A (zh) | 一种宠物用心脏病复方片剂 | |
CN102988478B (zh) | 一种治疗心脑血管疾病的中药组合物及制备方法 | |
CN102838651A (zh) | 一类齐墩果酸的衍生物及其制备方法和用途 | |
EP3804705B1 (en) | Pharmaceutical composition for preventing diabetes and use thereof | |
KR101894986B1 (ko) | 차나무의 잎, 꽃 및 씨 추출물을 포함하는 대사 증후군 예방 또는 개선용 조성물 | |
CN109260217A (zh) | 3`-脱氧次黄嘌呤核苷在制备用于多种疾病药品、食品或保健品中的应用 | |
CN105030806B (zh) | 一种治疗糖尿病的药物组合物及其用途 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
REG | Reference to a national code |
Ref country code: HK Ref legal event code: DE Ref document number: 1152485 Country of ref document: HK |
|
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
REG | Reference to a national code |
Ref country code: HK Ref legal event code: GR Ref document number: 1152485 Country of ref document: HK |
|
EE01 | Entry into force of recordation of patent licensing contract |
Application publication date: 20110504 Assignee: Tibet Linzhi Baisheng Pharmaceutical Co., Ltd. Assignor: Liaoning Sibaide Medical Technology Co., Ltd. Contract record no.: 2013210000036 Denomination of invention: Medicinal composition containing levocarnitine and hydroxybenzene sulfonate Granted publication date: 20120704 License type: Exclusive License Record date: 20130419 |
|
LICC | Enforcement, change and cancellation of record of contracts on the licence for exploitation of a patent or utility model | ||
CF01 | Termination of patent right due to non-payment of annual fee | ||
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20120704 Termination date: 20190629 |