IT1206954B - Agenti terapeutici a base di un acil derivato della carnitina per la cura di vasculopatie periferiche - Google Patents
Agenti terapeutici a base di un acil derivato della carnitina per la cura di vasculopatie perifericheInfo
- Publication number
- IT1206954B IT1206954B IT7947976A IT4797679A IT1206954B IT 1206954 B IT1206954 B IT 1206954B IT 7947976 A IT7947976 A IT 7947976A IT 4797679 A IT4797679 A IT 4797679A IT 1206954 B IT1206954 B IT 1206954B
- Authority
- IT
- Italy
- Prior art keywords
- acil
- carnitine
- derivative
- treatment
- therapeutic agents
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Priority Applications (19)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT7947976A IT1206954B (it) | 1979-02-12 | 1979-02-12 | Agenti terapeutici a base di un acil derivato della carnitina per la cura di vasculopatie periferiche |
DE19792911670 DE2911670A1 (de) | 1979-02-12 | 1979-03-24 | Arzneimittel zur therapeutischen behandlung von peripheren vaskularen erkrankungen |
US06/119,075 US4346107A (en) | 1979-02-12 | 1980-02-05 | Pharmaceutical composition comprising acyl-carnitine for the treatment of impaired cerebral metabolism |
US06/118,835 US4343816A (en) | 1979-02-12 | 1980-02-05 | Pharmaceutical composition comprising an acyl-carnitine, for treating peripheral vascular diseases |
AU55267/80A AU535518B2 (en) | 1979-02-12 | 1980-02-06 | Pharmaceutical compositions of acyl-carnitine |
AU55268/80A AU535565B2 (en) | 1979-02-12 | 1980-02-06 | Pharmaceutical compositions of acyl-carnitine |
NL8000741A NL8000741A (nl) | 1979-02-12 | 1980-02-06 | Een acylcarnitine bevattend farmaceutisch preparaat. |
NL8000768A NL8000768A (nl) | 1979-02-12 | 1980-02-07 | Een acyl-carnitine bevattend farmaceutisch preparaat. |
CH102780A CH642848A5 (it) | 1979-02-12 | 1980-02-08 | Composizione farmaceutica comprendente una acil-carnitina, per il trattamento di vasculopatie periferiche. |
CH102880A CH641673A5 (it) | 1979-02-12 | 1980-02-08 | Composizione farmaceutica comprendente una acil-carnitina per il trattamento del rallentato metabolismo cerebrale. |
BE0/199368A BE881680A (fr) | 1979-02-12 | 1980-02-12 | Composition pharmaceutique a base d'acylcarnitine pour le traitement d'un metabolisme cerebral altere et methode utilisee a cet effet |
FR8003014A FR2448347A1 (fr) | 1979-02-12 | 1980-02-12 | Composition pharmaceutique comprenant une acyl-carnitine pour le traitement des maladies vasculaires peripheriques |
FR8003015A FR2448348A1 (fr) | 1979-02-12 | 1980-02-12 | Composition pharmaceutique comprenant une acyl-carnitine pour le traitement du metabolisme cerebral perturbe |
JP1593080A JPS55136223A (en) | 1979-02-12 | 1980-02-12 | Brain metabolism obstruction treating agent |
GB8004602A GB2046593A (en) | 1979-02-12 | 1980-02-12 | Pharmaceutical compositions comprising acyl-carnitine for the treatment of impaired cerebral metabolism |
DE19803005208 DE3005208A1 (de) | 1979-02-12 | 1980-02-12 | Verwendung von acylcarnitin in arzneimitteln zur behandlung von stoerungen im gehirn-metabolismus |
JP1592980A JPS55136227A (en) | 1979-02-12 | 1980-02-12 | Peripheral vessel disease treating agent |
BE0/199369A BE881681A (fr) | 1979-02-12 | 1980-02-12 | Composition pharmaceutique a base d'acylcarnitine pour le traitement des maladies vasculaires peripheriques, et methode utilisee a cet effet |
GB8004599A GB2043443A (en) | 1979-02-12 | 1980-02-12 | Pharmaceutical compositions comprising an acyl-carnitine for treating pheripheral vascular diseases |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT7947976A IT1206954B (it) | 1979-02-12 | 1979-02-12 | Agenti terapeutici a base di un acil derivato della carnitina per la cura di vasculopatie periferiche |
Publications (2)
Publication Number | Publication Date |
---|---|
IT7947976A0 IT7947976A0 (it) | 1979-02-12 |
IT1206954B true IT1206954B (it) | 1989-05-17 |
Family
ID=11263725
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT7947976A IT1206954B (it) | 1979-02-12 | 1979-02-12 | Agenti terapeutici a base di un acil derivato della carnitina per la cura di vasculopatie periferiche |
Country Status (10)
Country | Link |
---|---|
US (1) | US4343816A (it) |
JP (2) | JPS55136227A (it) |
AU (1) | AU535565B2 (it) |
BE (1) | BE881681A (it) |
CH (1) | CH642848A5 (it) |
DE (1) | DE2911670A1 (it) |
FR (1) | FR2448347A1 (it) |
GB (1) | GB2043443A (it) |
IT (1) | IT1206954B (it) |
NL (1) | NL8000741A (it) |
Families Citing this family (43)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1142934B (it) * | 1981-11-06 | 1986-10-15 | Sigma Tau Ind Farmaceuti | Uso della carnitina e delle acilcarnitine inferiori nel trattamento terapeutico della patologia delle vene |
IT1157238B (it) * | 1982-10-29 | 1987-02-11 | Sigma Tau Ind Farmaceuti | Impiego di 1-carnitina per migliorare i paramenti biochimici e comportamentali dell'eta' senile |
IT1150396B (it) * | 1982-12-09 | 1986-12-10 | Sigma Tau Ind Farmaceuti | Impiego di alcanoil l-carnitine per il trattamento terapeutico di miopa tie e distrofie muscolari |
CH655005A5 (it) * | 1983-02-16 | 1986-03-27 | Sigma Tau Ind Farmaceuti | Composizione farmaceutica ad azione metabolica ed energetica utilizzabile in terapia cardiaca e vascolare. |
IT1181682B (it) * | 1985-06-11 | 1987-09-30 | Sigma Tau Ind Farmaceuti | Impiego di alcanoil l-carnitine per il trattamento terapeutico del parkinsonismo idiopatico o indotto |
IT1224842B (it) * | 1988-12-27 | 1990-10-24 | Sigma Tau Ind Farmaceuti | Uso di derivati della l-carnitina nel trattamento terapeutico delle alterazioni degenerative del sistema nervoso |
IT1230141B (it) * | 1989-05-03 | 1991-10-14 | Fidia Spa | Impiego di derivati della fosfatidil carnitina per la preparazione di composizioni farmaceutiche aventi attivita' nella terapia delle patologie dell'uomo associate con un danno neuronale. |
IT1231944B (it) * | 1989-05-05 | 1992-01-16 | Sigma Tau Ind Farmaceuti | Composizione farmaceutica per il trattamento di protozoosi, particolarmente della tripasonomiasi comprendente d-carnitina o un alcanoilderivato della d-carnitina |
IT1263004B (it) * | 1992-10-08 | 1996-07-23 | Sigma Tau Ind Farmaceuti | Impiego della l-carnitina e acil l-carnitine nel trattamento a lungo termine di pazienti diabetici non insulino-dipendenti. |
US5741816A (en) * | 1994-06-20 | 1998-04-21 | Tanabe Seiyaku Co., Ltd. | Hair-growth agent |
AU6482596A (en) * | 1995-07-03 | 1997-02-05 | Wilson T. Crandall | Transdermal and oral treatment of androgenic alopecia |
IT1276225B1 (it) * | 1995-10-17 | 1997-10-27 | Sigma Tau Ind Farmaceuti | Composizioni farmaceutiche contenenti l-carnitina e alcanoil l- carnitine in associazione con resveratrolo o suoi derivati utili per |
DE69605531T2 (de) * | 1996-03-04 | 2000-05-31 | Sigma Tau Ind Farmaceuti | Carnitinderivat als Arzneimittel zur Behandlung von Arteriosklerose obliterans |
ES2530753T3 (es) * | 1997-03-17 | 2015-03-05 | Btg Int Ltd | Composiciones terapéuticas que comprenden cuerpos cetónicos y precursores de los mismos |
IT1291127B1 (it) * | 1997-04-01 | 1998-12-29 | Sigma Tau Ind Farmaceuti | Integratore alimentare per soggetti dediti ad intensa e prolungata attivita' fisica |
AU1258699A (en) * | 1998-11-11 | 2000-05-29 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Use of propionylcarnitine for the manufacture of a medicament for inhibiting smooth muscle cell proliferation |
AU1295700A (en) * | 1998-11-26 | 2000-06-13 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Use of fumarate salt of l-carnitine or its alkanoyl derivatives in ischaemia |
US6616942B1 (en) | 1999-03-29 | 2003-09-09 | Soft Gel Technologies, Inc. | Coenzyme Q10 formulation and process methodology for soft gel capsules manufacturing |
US6562869B1 (en) | 1999-09-23 | 2003-05-13 | Juvenon, Inc. | Nutritional supplement for increased energy and stamina |
US20070072927A1 (en) * | 1999-09-23 | 2007-03-29 | Vita Joseph A | Nutritional supplement for increased energy and stamina |
AU7828200A (en) | 1999-09-23 | 2001-04-24 | Juvenon Corporation | Nutritional supplement for increased energy and stamina |
IT1307278B1 (it) * | 1999-11-18 | 2001-10-30 | Sigma Tau Healthscience Spa | Composizione per la prevenzione e/o il trattamento di disturbi dovutiad un alterato metabolismo dei lipidi, che comprende propionil |
US7713546B1 (en) | 2001-04-03 | 2010-05-11 | Soft Gel Technologies, Inc. | Corosolic acid formulation and its application for weight-loss management and blood sugar balance |
US6964494B2 (en) | 2001-01-22 | 2005-11-15 | Eflare Corporation Pty Ltd | Safety/warning device |
ITRM20020620A1 (it) * | 2002-12-13 | 2004-06-14 | Sigma Tau Ind Farmaceuti | Uso delle carnitine per la prevenzione e/o il trattamento dei disturbi causati dall'andropausa. |
US20080089877A1 (en) * | 2003-08-14 | 2008-04-17 | Udell Ronald G | Super Absorption Coenzyme Q10 |
US7169385B2 (en) * | 2003-09-29 | 2007-01-30 | Ronald G. Udell | Solubilized CoQ-10 and carnitine |
US8105583B2 (en) | 2003-09-29 | 2012-01-31 | Soft Gel Technologies, Inc. | Solubilized CoQ-10 |
US8124072B2 (en) | 2003-09-29 | 2012-02-28 | Soft Gel Technologies, Inc. | Solubilized CoQ-10 |
GB0323348D0 (en) * | 2003-10-06 | 2003-11-05 | Cambridge Theranostics Ltd | Methods and means for modulating lipid metabolism |
US20050232911A1 (en) * | 2004-04-19 | 2005-10-20 | Schreiber Brian D | Prevention and treatment of metabolic abnormalities associated with excess intramyocellular lipid |
US20060051435A1 (en) * | 2004-08-19 | 2006-03-09 | Udell Ronald G | Nutritional supplement for body fat reduction |
WO2006061341A1 (en) * | 2004-12-10 | 2006-06-15 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Use of propionyl l-carnitine for the preparation of a high-dose medicament for the treatment of peripheral arterial disease |
US7887852B2 (en) * | 2005-06-03 | 2011-02-15 | Soft Gel Technologies, Inc. | Soft gel capsules containing polymethoxylated flavones and palm oil tocotrienols |
US20050249803A1 (en) * | 2005-06-03 | 2005-11-10 | Udell Ronald G | Soft gel capsules containing polymethoxylated flavones and palm oil tocotrienols |
US20070104805A1 (en) * | 2005-11-01 | 2007-05-10 | Udell Ronald G | Compositions of Hoodia Gordonii and Pinolenic Acid Derivatives |
JP2009037201A (ja) * | 2007-03-14 | 2009-02-19 | Fujifilm Corp | 感光性樹脂組成物、それを用いた硬化レリーフパターンの製造方法及び半導体装置 |
US20080226696A1 (en) * | 2007-03-15 | 2008-09-18 | Ben Treadwell | Methods of improving learning abilities of aged companion animals |
US8343541B2 (en) | 2007-03-15 | 2013-01-01 | Soft Gel Technologies, Inc. | Ubiquinol and alpha lipoic acid compositions |
EP2353596A1 (en) | 2010-02-02 | 2011-08-10 | SIGMA-TAU Industrie Farmaceutiche Riunite S.p.A. | Combination composition, comprising as active ingredients L-carnitine or propionyl L-carnitine, for the prevention or treatment of chronic venous insufficiency |
KR20130089158A (ko) | 2010-06-16 | 2013-08-09 | 시구마-토우인더스트리에파아마슈우티히리유니트에스.피이.에이. | 신경 조직에서 신경발생을 증가시키기 위한 방법에 사용하기 위한 아세틸-카르니틴 |
CA3172190A1 (en) | 2020-05-15 | 2021-11-18 | Alfasigma S.P.A. | Composition comprising methylfolate |
IT202100020729A1 (it) | 2021-08-02 | 2023-02-02 | Univ Degli Studi Di Napoli Federico Ii | Preparazione combinata per il trattamento della malattia di Pompe |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE700864A (it) * | 1967-07-03 | 1967-12-18 | ||
GB1256162A (en) * | 1968-08-16 | 1971-12-08 | Braun Fa B | Improvements in and relating to liquid products for intravenous administration |
US3810994A (en) * | 1972-06-01 | 1974-05-14 | Ethyl Corp | Method and composition for treating obesity |
JPS531812B2 (it) * | 1972-12-07 | 1978-01-23 | ||
JPS5058213A (it) * | 1973-09-26 | 1975-05-21 | ||
AU518617B2 (en) * | 1977-04-29 | 1981-10-08 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Therapeutic application of acetyl-d, 1-carnitine |
IT1143611B (it) * | 1977-11-03 | 1986-10-22 | Sigma Tau Ind Farmaceuti | Applicazione della acetil-carnitina nella terapia delle affezioni cardiache di/tipo anossico,ischemico,cardiotossico e nelle sindromi aritmiche |
FR2414914A1 (fr) * | 1978-01-18 | 1979-08-17 | Sigma Tau Ind Farmaceuti | Utilisations therapeutiques nouvelles de l'acetyl-1-carnitine et d'autres derives acyles de la 1-carnitine |
DE2903579A1 (de) * | 1978-02-03 | 1979-08-09 | Sigma Tau Ind Farmaceuti | Verwendung von acetylcarnitin und anderen acylderivaten des carnitins zur behandlung der hyperlipoproteinaemie und hyperlimpidaemie sowie arzneimittel |
IT1156741B (it) * | 1978-05-15 | 1987-02-04 | Sigma Tau Ind Farmaceuti | Applicazione terapeutica della carnitina e di alcuni derivati acilati della carnitina nell'emodialisi |
-
1979
- 1979-02-12 IT IT7947976A patent/IT1206954B/it active Protection Beyond IP Right Term
- 1979-03-24 DE DE19792911670 patent/DE2911670A1/de not_active Ceased
-
1980
- 1980-02-05 US US06/118,835 patent/US4343816A/en not_active Expired - Lifetime
- 1980-02-06 AU AU55268/80A patent/AU535565B2/en not_active Expired
- 1980-02-06 NL NL8000741A patent/NL8000741A/nl not_active Application Discontinuation
- 1980-02-08 CH CH102780A patent/CH642848A5/it not_active IP Right Cessation
- 1980-02-12 FR FR8003014A patent/FR2448347A1/fr active Pending
- 1980-02-12 BE BE0/199369A patent/BE881681A/fr not_active IP Right Cessation
- 1980-02-12 JP JP1592980A patent/JPS55136227A/ja active Granted
- 1980-02-12 GB GB8004599A patent/GB2043443A/en not_active Withdrawn
- 1980-02-12 JP JP1593080A patent/JPS55136223A/ja active Granted
Also Published As
Publication number | Publication date |
---|---|
DE2911670A1 (de) | 1980-08-14 |
CH642848A5 (it) | 1984-05-15 |
US4343816A (en) | 1982-08-10 |
JPS55136223A (en) | 1980-10-23 |
AU5526880A (en) | 1980-08-21 |
AU535565B2 (en) | 1984-03-29 |
JPH0233014B2 (it) | 1990-07-25 |
IT7947976A0 (it) | 1979-02-12 |
NL8000741A (nl) | 1980-08-14 |
FR2448347A1 (fr) | 1980-09-05 |
JPH0233015B2 (it) | 1990-07-25 |
GB2043443A (en) | 1980-10-08 |
JPS55136227A (en) | 1980-10-23 |
BE881681A (fr) | 1980-05-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MEDI | Supplementary protection certificate for pharmaceutical products: court of cassation |
Free format text: CCP 502, 19950511; SIGMA-TAU INDUSTRIE FARMACEUTICHE R IUNITE S.P.A |
|
TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19961216 |
|
MEDD | Supplementary protection certificate for pharmaceutical products: granted |
Free format text: CCP 502, 19950511; SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A |