FR2448347A1 - Composition pharmaceutique comprenant une acyl-carnitine pour le traitement des maladies vasculaires peripheriques - Google Patents

Composition pharmaceutique comprenant une acyl-carnitine pour le traitement des maladies vasculaires peripheriques

Info

Publication number
FR2448347A1
FR2448347A1 FR8003014A FR8003014A FR2448347A1 FR 2448347 A1 FR2448347 A1 FR 2448347A1 FR 8003014 A FR8003014 A FR 8003014A FR 8003014 A FR8003014 A FR 8003014A FR 2448347 A1 FR2448347 A1 FR 2448347A1
Authority
FR
France
Prior art keywords
treatment
acyl
carnitine
pharmaceutical composition
peripheral vascular
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
FR8003014A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of FR2448347A1 publication Critical patent/FR2448347A1/fr
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Emergency Medicine (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurosurgery (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

SELON L'INVENTION, UNE COMPOSITION PHARMACEUTIQUE CONTENANT UNE ACYL-CARNITINE DANS LAQUELLE LE RADICAL ACYLE EST CHOISI PARMI LES RADICAUX ACETYLE, PROPIONYLE, BUTYRYLE, HYDROXYBUTYRYLE ET ACETOACETYLE, EST UTILISABLE DANS LE TRAITEMENT THERAPEUTIQUE DES MALADIES VASCULAIRES PERIPHERIQUES (TYPIQUEMENT, LA MALADIE DE RAYNAUD).
FR8003014A 1979-02-12 1980-02-12 Composition pharmaceutique comprenant une acyl-carnitine pour le traitement des maladies vasculaires peripheriques Pending FR2448347A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT7947976A IT1206954B (it) 1979-02-12 1979-02-12 Agenti terapeutici a base di un acil derivato della carnitina per la cura di vasculopatie periferiche

Publications (1)

Publication Number Publication Date
FR2448347A1 true FR2448347A1 (fr) 1980-09-05

Family

ID=11263725

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8003014A Pending FR2448347A1 (fr) 1979-02-12 1980-02-12 Composition pharmaceutique comprenant une acyl-carnitine pour le traitement des maladies vasculaires peripheriques

Country Status (10)

Country Link
US (1) US4343816A (fr)
JP (2) JPS55136223A (fr)
AU (1) AU535565B2 (fr)
BE (1) BE881681A (fr)
CH (1) CH642848A5 (fr)
DE (1) DE2911670A1 (fr)
FR (1) FR2448347A1 (fr)
GB (1) GB2043443A (fr)
IT (1) IT1206954B (fr)
NL (1) NL8000741A (fr)

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IT1142934B (it) * 1981-11-06 1986-10-15 Sigma Tau Ind Farmaceuti Uso della carnitina e delle acilcarnitine inferiori nel trattamento terapeutico della patologia delle vene
IT1157238B (it) * 1982-10-29 1987-02-11 Sigma Tau Ind Farmaceuti Impiego di 1-carnitina per migliorare i paramenti biochimici e comportamentali dell'eta' senile
IT1150396B (it) * 1982-12-09 1986-12-10 Sigma Tau Ind Farmaceuti Impiego di alcanoil l-carnitine per il trattamento terapeutico di miopa tie e distrofie muscolari
CH655005A5 (it) * 1983-02-16 1986-03-27 Sigma Tau Ind Farmaceuti Composizione farmaceutica ad azione metabolica ed energetica utilizzabile in terapia cardiaca e vascolare.
IT1181682B (it) * 1985-06-11 1987-09-30 Sigma Tau Ind Farmaceuti Impiego di alcanoil l-carnitine per il trattamento terapeutico del parkinsonismo idiopatico o indotto
IT1224842B (it) * 1988-12-27 1990-10-24 Sigma Tau Ind Farmaceuti Uso di derivati della l-carnitina nel trattamento terapeutico delle alterazioni degenerative del sistema nervoso
IT1230141B (it) * 1989-05-03 1991-10-14 Fidia Spa Impiego di derivati della fosfatidil carnitina per la preparazione di composizioni farmaceutiche aventi attivita' nella terapia delle patologie dell'uomo associate con un danno neuronale.
IT1231944B (it) * 1989-05-05 1992-01-16 Sigma Tau Ind Farmaceuti Composizione farmaceutica per il trattamento di protozoosi, particolarmente della tripasonomiasi comprendente d-carnitina o un alcanoilderivato della d-carnitina
IT1263004B (it) * 1992-10-08 1996-07-23 Sigma Tau Ind Farmaceuti Impiego della l-carnitina e acil l-carnitine nel trattamento a lungo termine di pazienti diabetici non insulino-dipendenti.
US5741816A (en) * 1994-06-20 1998-04-21 Tanabe Seiyaku Co., Ltd. Hair-growth agent
WO1997002041A1 (fr) * 1995-07-03 1997-01-23 Crandall Wilson T Traitement transcutane et oral de l'alopecie androgene
IT1276225B1 (it) * 1995-10-17 1997-10-27 Sigma Tau Ind Farmaceuti Composizioni farmaceutiche contenenti l-carnitina e alcanoil l- carnitine in associazione con resveratrolo o suoi derivati utili per
EP0793962B1 (fr) * 1996-03-04 1999-12-08 Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. Médicament contenant un dérivé de carnitine pour le traitement de l'artériosclérose obliterans
AU6513298A (en) * 1997-03-17 1998-10-12 British Technology Group Limited Therapeutic compositions
IT1291127B1 (it) * 1997-04-01 1998-12-29 Sigma Tau Ind Farmaceuti Integratore alimentare per soggetti dediti ad intensa e prolungata attivita' fisica
WO2000027386A1 (fr) * 1998-11-11 2000-05-18 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Procede d'utilisation de la l-carnitine de propionyle pour fabriquer un medicament destine a inhiber la proliferation des cellules musculaires lisses
WO2000030637A1 (fr) * 1998-11-26 2000-06-02 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Utilisation d'un sel de fumarate de l carnitine, ou de ses derives alcanoyles, pour lutter contre l'ischemie
US6616942B1 (en) 1999-03-29 2003-09-09 Soft Gel Technologies, Inc. Coenzyme Q10 formulation and process methodology for soft gel capsules manufacturing
WO2001021208A1 (fr) 1999-09-23 2001-03-29 Juvenon Corporation Supplement nutritionnel fournissant une energie et une endurance accrues
US6562869B1 (en) 1999-09-23 2003-05-13 Juvenon, Inc. Nutritional supplement for increased energy and stamina
US20070072927A1 (en) * 1999-09-23 2007-03-29 Vita Joseph A Nutritional supplement for increased energy and stamina
IT1307278B1 (it) * 1999-11-18 2001-10-30 Sigma Tau Healthscience Spa Composizione per la prevenzione e/o il trattamento di disturbi dovutiad un alterato metabolismo dei lipidi, che comprende propionil
US7713546B1 (en) * 2001-04-03 2010-05-11 Soft Gel Technologies, Inc. Corosolic acid formulation and its application for weight-loss management and blood sugar balance
US6964494B2 (en) 2001-01-22 2005-11-15 Eflare Corporation Pty Ltd Safety/warning device
ITRM20020620A1 (it) * 2002-12-13 2004-06-14 Sigma Tau Ind Farmaceuti Uso delle carnitine per la prevenzione e/o il trattamento dei disturbi causati dall'andropausa.
US20080089877A1 (en) * 2003-08-14 2008-04-17 Udell Ronald G Super Absorption Coenzyme Q10
US8124072B2 (en) 2003-09-29 2012-02-28 Soft Gel Technologies, Inc. Solubilized CoQ-10
EP1670325A1 (fr) 2003-09-29 2006-06-21 Soft Gel Technologies, Inc. Coq-10 solubilise
US7169385B2 (en) * 2003-09-29 2007-01-30 Ronald G. Udell Solubilized CoQ-10 and carnitine
GB0323348D0 (en) * 2003-10-06 2003-11-05 Cambridge Theranostics Ltd Methods and means for modulating lipid metabolism
US20050232911A1 (en) * 2004-04-19 2005-10-20 Schreiber Brian D Prevention and treatment of metabolic abnormalities associated with excess intramyocellular lipid
US20060051435A1 (en) * 2004-08-19 2006-03-09 Udell Ronald G Nutritional supplement for body fat reduction
WO2006061341A1 (fr) * 2004-12-10 2006-06-15 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Utilisation de propionyl l-carnitine pour la preparation d'un medicament fortement dose pour le traitement de maladie arterielle peripherique
US20050249803A1 (en) * 2005-06-03 2005-11-10 Udell Ronald G Soft gel capsules containing polymethoxylated flavones and palm oil tocotrienols
US7887852B2 (en) * 2005-06-03 2011-02-15 Soft Gel Technologies, Inc. Soft gel capsules containing polymethoxylated flavones and palm oil tocotrienols
US20070104805A1 (en) * 2005-11-01 2007-05-10 Udell Ronald G Compositions of Hoodia Gordonii and Pinolenic Acid Derivatives
ATE547743T1 (de) * 2007-03-14 2012-03-15 Fujifilm Corp Lichtempfindliche zusammensetzung und herstellungsverfahren für ein gehärtetes reliefmuster
US20080226696A1 (en) * 2007-03-15 2008-09-18 Ben Treadwell Methods of improving learning abilities of aged companion animals
US8343541B2 (en) 2007-03-15 2013-01-01 Soft Gel Technologies, Inc. Ubiquinol and alpha lipoic acid compositions
EP2353596A1 (fr) 2010-02-02 2011-08-10 SIGMA-TAU Industrie Farmaceutiche Riunite S.p.A. Composition combinée comprenant en tant que principes actifs de la L-carnitine ou de la propionyl L-carnitine pour la prévention d'une insuffisance veineuse chronique
EP2582368B1 (fr) 2010-06-16 2018-05-09 Alfasigma S.p.A. Acetyl-Lcarnitine pour augmenter la neurogénèse dans le tissu neuronal
US20230181475A1 (en) 2020-05-15 2023-06-15 Alfasigma S.P.A. Composition comprising methylfolate
IT202100020729A1 (it) 2021-08-02 2023-02-02 Univ Degli Studi Di Napoli Federico Ii Preparazione combinata per il trattamento della malattia di Pompe

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1573430A (fr) * 1967-07-03 1969-07-04
FR2209545A1 (fr) * 1972-12-07 1974-07-05 Otsuka Pharma Co Ltd
FR2244487A1 (fr) * 1973-09-26 1975-04-18 Kawashima Yuzo
FR2388556A1 (fr) * 1977-04-29 1978-11-24 Sigma Tau Ind Farmaceuti Application therapeutique de l'acetyl-carnitine-d,1 et d'autres derives acyliques de la carnitine-d,1
FR2407717A1 (fr) * 1977-11-03 1979-06-01 Sigma Tau Ind Farmaceuti Usage therapeutique nouveau de l'acetyl-1-carnitine
FR2414914A1 (fr) * 1978-01-18 1979-08-17 Sigma Tau Ind Farmaceuti Utilisations therapeutiques nouvelles de l'acetyl-1-carnitine et d'autres derives acyles de la 1-carnitine
FR2425855A1 (fr) * 1978-05-15 1979-12-14 Cavazza Claudio Application des acyl-carnitines a un procede therapeutique de traitement de patients uremiques chroniques en traitement hemodialytique periodique et composition liquide de dialyse pour la mise en oeuvre d'un tel procede

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US3810994A (en) * 1972-06-01 1974-05-14 Ethyl Corp Method and composition for treating obesity
DE2903579A1 (de) * 1978-02-03 1979-08-09 Sigma Tau Ind Farmaceuti Verwendung von acetylcarnitin und anderen acylderivaten des carnitins zur behandlung der hyperlipoproteinaemie und hyperlimpidaemie sowie arzneimittel

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1573430A (fr) * 1967-07-03 1969-07-04
FR2209545A1 (fr) * 1972-12-07 1974-07-05 Otsuka Pharma Co Ltd
FR2244487A1 (fr) * 1973-09-26 1975-04-18 Kawashima Yuzo
FR2388556A1 (fr) * 1977-04-29 1978-11-24 Sigma Tau Ind Farmaceuti Application therapeutique de l'acetyl-carnitine-d,1 et d'autres derives acyliques de la carnitine-d,1
FR2407717A1 (fr) * 1977-11-03 1979-06-01 Sigma Tau Ind Farmaceuti Usage therapeutique nouveau de l'acetyl-1-carnitine
FR2414914A1 (fr) * 1978-01-18 1979-08-17 Sigma Tau Ind Farmaceuti Utilisations therapeutiques nouvelles de l'acetyl-1-carnitine et d'autres derives acyles de la 1-carnitine
FR2425855A1 (fr) * 1978-05-15 1979-12-14 Cavazza Claudio Application des acyl-carnitines a un procede therapeutique de traitement de patients uremiques chroniques en traitement hemodialytique periodique et composition liquide de dialyse pour la mise en oeuvre d'un tel procede

Also Published As

Publication number Publication date
IT1206954B (it) 1989-05-17
BE881681A (fr) 1980-05-30
IT7947976A0 (it) 1979-02-12
AU5526880A (en) 1980-08-21
GB2043443A (en) 1980-10-08
JPH0233015B2 (fr) 1990-07-25
JPS55136223A (en) 1980-10-23
CH642848A5 (it) 1984-05-15
JPS55136227A (en) 1980-10-23
US4343816A (en) 1982-08-10
JPH0233014B2 (fr) 1990-07-25
AU535565B2 (en) 1984-03-29
DE2911670A1 (de) 1980-08-14
NL8000741A (nl) 1980-08-14

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