FR2425855A1 - Application des acyl-carnitines a un procede therapeutique de traitement de patients uremiques chroniques en traitement hemodialytique periodique et composition liquide de dialyse pour la mise en oeuvre d'un tel procede - Google Patents

Application des acyl-carnitines a un procede therapeutique de traitement de patients uremiques chroniques en traitement hemodialytique periodique et composition liquide de dialyse pour la mise en oeuvre d'un tel procede

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Publication number
FR2425855A1
FR2425855A1 FR7912197A FR7912197A FR2425855A1 FR 2425855 A1 FR2425855 A1 FR 2425855A1 FR 7912197 A FR7912197 A FR 7912197A FR 7912197 A FR7912197 A FR 7912197A FR 2425855 A1 FR2425855 A1 FR 2425855A1
Authority
FR
France
Prior art keywords
treatment
hemodialytic
patients
acyl
periodic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7912197A
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English (en)
Other versions
FR2425855B1 (fr
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Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of FR2425855A1 publication Critical patent/FR2425855A1/fr
Application granted granted Critical
Publication of FR2425855B1 publication Critical patent/FR2425855B1/fr
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1654—Dialysates therefor

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • External Artificial Organs (AREA)
  • Medicinal Preparation (AREA)

Abstract

Procédé thérapeutique pour traiter des patients urémiques chroniques en traitement hémodialytique périodique, caractérisé en ce qu'il consiste à administrer par voie orale à de tels patients tant les jours du traitement hémodialityque que les jours compris entre un traitement hémodialytique et le suivant, de 3 à 6 g par jour d'une acyl-carnitine de formule générale :
FR7912197A 1978-05-15 1979-05-14 Application des acyl-carnitines a un procede therapeutique de traitement de patients uremiques chroniques en traitement hemodialytique periodique et composition liquide de dialyse pour la mise en oeuvre d'un tel procede Granted FR2425855A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT49355/78A IT1156741B (it) 1978-05-15 1978-05-15 Applicazione terapeutica della carnitina e di alcuni derivati acilati della carnitina nell'emodialisi

Publications (2)

Publication Number Publication Date
FR2425855A1 true FR2425855A1 (fr) 1979-12-14
FR2425855B1 FR2425855B1 (fr) 1983-09-16

Family

ID=11270450

Family Applications (2)

Application Number Title Priority Date Filing Date
FR7912196A Granted FR2425854A1 (fr) 1978-05-15 1979-05-14 Procede therapeutique pour traiter les patients uremiques chroniques en traitement hemodialytique periodique et composition liquide de dialyse pour la mise en oeuvre de ce procede
FR7912197A Granted FR2425855A1 (fr) 1978-05-15 1979-05-14 Application des acyl-carnitines a un procede therapeutique de traitement de patients uremiques chroniques en traitement hemodialytique periodique et composition liquide de dialyse pour la mise en oeuvre d'un tel procede

Family Applications Before (1)

Application Number Title Priority Date Filing Date
FR7912196A Granted FR2425854A1 (fr) 1978-05-15 1979-05-14 Procede therapeutique pour traiter les patients uremiques chroniques en traitement hemodialytique periodique et composition liquide de dialyse pour la mise en oeuvre de ce procede

Country Status (14)

Country Link
US (2) US4272549A (fr)
JP (2) JPS54151131A (fr)
BE (2) BE876263A (fr)
CA (2) CA1134274A (fr)
CH (2) CH642549A5 (fr)
DE (2) DE2919593A1 (fr)
DK (2) DK198179A (fr)
FR (2) FR2425854A1 (fr)
GB (2) GB2020550B (fr)
IE (2) IE48122B1 (fr)
IL (2) IL57265A0 (fr)
IT (1) IT1156741B (fr)
LU (2) LU81264A1 (fr)
NL (2) NL7903824A (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2448348A1 (fr) * 1979-02-12 1980-09-05 Cavazza Claudio Composition pharmaceutique comprenant une acyl-carnitine pour le traitement du metabolisme cerebral perturbe
FR2448347A1 (fr) * 1979-02-12 1980-09-05 Cavazza Claudio Composition pharmaceutique comprenant une acyl-carnitine pour le traitement des maladies vasculaires peripheriques
FR2468371A1 (fr) * 1979-10-05 1981-05-08 Sigma Tau Ind Farmaceuti Compositions pharmaceutiques pour nutrition parenterale

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1156741B (it) * 1978-05-15 1987-02-04 Sigma Tau Ind Farmaceuti Applicazione terapeutica della carnitina e di alcuni derivati acilati della carnitina nell'emodialisi
DE2921852A1 (de) * 1979-05-29 1980-12-11 Fresenius Chem Pharm Ind Lipide senkendes mittel
JPS5661314A (en) * 1979-10-24 1981-05-26 Otsuka Pharmaceut Factory Inc Preventive against side-effect for dialytic patient
US4335335A (en) * 1980-02-11 1982-06-15 Rca Corporation Television receiver high voltage protection circuit
IT1145362B (it) * 1980-03-06 1986-11-05 Sigma Tau Ind Farmaceuti Classe di acil-derivati della carnitina procedimento per la loro preparazione e loro uso terapeutico
IT1145371B (it) * 1980-05-30 1986-11-05 Sigma Tau Ind Farmaceuti Alcossi-acil carnitine procedimento per la loro preparazione e composizioni farmaceutiche che le contengono
IT1147079B (it) * 1980-05-30 1986-11-19 Sigma Tau Ind Farmacuetiche Ri Esteri di alcossi-acil derivati della carnitina procedimento per la loro preparatione e composizioni farmaceutiche che li contengono
DE3224823A1 (de) * 1982-07-02 1984-01-05 Lentia GmbH Chem. u. pharm. Erzeugnisse - Industriebedarf, 8000 München Verfahren zur herstellung einer fuer den entsprechenden krankheitsfall optimierten elektrolytloesung zur anwendung in der haemodialyse
US4737544A (en) * 1982-08-12 1988-04-12 Biospecific Technologies, Inc. Biospecific polymers
US4687808A (en) * 1982-08-12 1987-08-18 Biospecific Technologies, Inc. Activation of biocompatible polymers with biologicals whose binding complements are pathological effectors
IT1157238B (it) * 1982-10-29 1987-02-11 Sigma Tau Ind Farmaceuti Impiego di 1-carnitina per migliorare i paramenti biochimici e comportamentali dell'eta' senile
US5719119A (en) * 1985-12-18 1998-02-17 British Technology Group, Ltd. Parenteral nutrition therapy with amino acids
DE3821043A1 (de) * 1988-06-22 1989-12-28 Fresenius Ag Dialysier- und spuel-loesung zur intraperitonealen verabreichung
US6498142B1 (en) 1996-05-06 2002-12-24 Curis, Inc. Morphogen treatment for chronic renal failure
EP0980252B1 (fr) 1997-05-05 2004-10-06 Curis, Inc. Therapies contre l'insuffisance renale aigue
US6537976B1 (en) 1997-08-07 2003-03-25 Ajay Gupta Dialysis solutions containing water soluble vitamins and nutrients
KR100461572B1 (ko) * 1999-03-27 2004-12-14 삼성정밀화학 주식회사 Ｌ-카르니틴 칼슘 염과 이의 제조방법
BE1012930A3 (fr) * 1999-10-08 2001-06-05 Lhoist Rech & Dev Sa Produit a base d'oxyde de calcium et son procede de fabrication.
SK288072B6 (sk) * 1999-10-11 2013-05-03 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Use of L-carnitine and its alkanoyl derivatives as osmotic agents in solutions for medical use
US6429230B1 (en) * 2000-01-19 2002-08-06 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Treating chronic uremic patients undergoing periodical dialysis
AU2001230502A1 (en) * 2000-01-19 2001-07-31 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Intravenous carnitine for the treatment of chronic uraemic patients undergoing periodical dialysis
US6335369B1 (en) * 2000-01-19 2002-01-01 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Treating chronic uremic patients undergoing periodical dialysis
US6914076B2 (en) * 2000-01-19 2005-07-05 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Treating chronic uremic patients undergoing periodical dialysis
US20050232911A1 (en) * 2004-04-19 2005-10-20 Schreiber Brian D Prevention and treatment of metabolic abnormalities associated with excess intramyocellular lipid
JP2006075195A (ja) * 2004-09-07 2006-03-23 Jms Co Ltd Ｌカルニチン含有腹膜透析液
US20070087975A1 (en) * 2005-10-17 2007-04-19 Sigma-Tau Industrie Farmaceutiche Riunite Spa Compound useful for the prevention and treatment of left ventricular hypertrophy in dialysed patients
GR1009311B (el) * 2017-01-26 2018-06-19 Βερμα Ντραγκς - Verma Drugs Abee Οξινο κιτρικο διαλυμα αιμοκαθαρσης με l-καρνιτινη

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3810994A (en) * 1972-06-01 1974-05-14 Ethyl Corp Method and composition for treating obesity
FR2244487A1 (fr) * 1973-09-26 1975-04-18 Kawashima Yuzo
JPS53124610A (en) * 1977-05-17 1978-10-31 Sodekusu:Kk Dialysate
FR2388556A1 (fr) * 1977-04-29 1978-11-24 Sigma Tau Ind Farmaceuti Application therapeutique de l'acetyl-carnitine-d,1 et d'autres derives acyliques de la carnitine-d,1
JPS5428809A (en) * 1977-08-08 1979-03-03 Medekusu Kk Injection solution for filter type artificial kidney
FR2407717A1 (fr) * 1977-11-03 1979-06-01 Sigma Tau Ind Farmaceuti Usage therapeutique nouveau de l'acetyl-1-carnitine
GB2013496A (en) * 1978-02-03 1979-08-15 Sigma Tau Ind Farmaceuti Treating hyperlipoproteinaemias and hyperlipidaemias
FR2414914A1 (fr) * 1978-01-18 1979-08-17 Sigma Tau Ind Farmaceuti Utilisations therapeutiques nouvelles de l'acetyl-1-carnitine et d'autres derives acyles de la 1-carnitine

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3822344A (en) * 1967-04-28 1974-07-02 Cox & Co Ltd A Pharmaceutical compositions providing potassium chloride in aqueous solution
ES356006A1 (es) * 1967-07-03 1969-12-16 Italseber Sa Procedimiento para la preparacion de clorhidrato de acetoa-cetilcarnitina dextrogira y levogira.
US3830931A (en) * 1972-11-06 1974-08-20 Felice S De Carnitine and its use in the treatment of arrhythmia and impaired cardiac function
US3968241A (en) * 1972-11-06 1976-07-06 Defelice Stephen L Method of treating cardiac arrhythmias and of improving myocardial contractility and systolic rhythm with carnitive or a pharmaceutically acceptable salt thereof
DE2903558C2 (de) * 1978-02-03 1994-09-01 Sigma Tau Ind Farmaceuti Verwendung von L-Carnitin
IT1156741B (it) * 1978-05-15 1987-02-04 Sigma Tau Ind Farmaceuti Applicazione terapeutica della carnitina e di alcuni derivati acilati della carnitina nell'emodialisi

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3810994A (en) * 1972-06-01 1974-05-14 Ethyl Corp Method and composition for treating obesity
FR2244487A1 (fr) * 1973-09-26 1975-04-18 Kawashima Yuzo
FR2388556A1 (fr) * 1977-04-29 1978-11-24 Sigma Tau Ind Farmaceuti Application therapeutique de l'acetyl-carnitine-d,1 et d'autres derives acyliques de la carnitine-d,1
JPS53124610A (en) * 1977-05-17 1978-10-31 Sodekusu:Kk Dialysate
JPS5428809A (en) * 1977-08-08 1979-03-03 Medekusu Kk Injection solution for filter type artificial kidney
FR2407717A1 (fr) * 1977-11-03 1979-06-01 Sigma Tau Ind Farmaceuti Usage therapeutique nouveau de l'acetyl-1-carnitine
FR2414914A1 (fr) * 1978-01-18 1979-08-17 Sigma Tau Ind Farmaceuti Utilisations therapeutiques nouvelles de l'acetyl-1-carnitine et d'autres derives acyles de la 1-carnitine
GB2013496A (en) * 1978-02-03 1979-08-15 Sigma Tau Ind Farmaceuti Treating hyperlipoproteinaemias and hyperlipidaemias

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
CA1979 *
EXBK/73 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2448348A1 (fr) * 1979-02-12 1980-09-05 Cavazza Claudio Composition pharmaceutique comprenant une acyl-carnitine pour le traitement du metabolisme cerebral perturbe
FR2448347A1 (fr) * 1979-02-12 1980-09-05 Cavazza Claudio Composition pharmaceutique comprenant une acyl-carnitine pour le traitement des maladies vasculaires peripheriques
FR2468371A1 (fr) * 1979-10-05 1981-05-08 Sigma Tau Ind Farmaceuti Compositions pharmaceutiques pour nutrition parenterale

Also Published As

Publication number Publication date
DE2919593A1 (de) 1979-11-22
JPS54151131A (en) 1979-11-28
LU81264A1 (fr) 1979-09-10
CH642549A5 (it) 1984-04-30
GB2020552A (en) 1979-11-21
IL57267A0 (en) 1979-09-30
IE790952L (en) 1979-11-15
FR2425855B1 (fr) 1983-09-16
FR2425854A1 (fr) 1979-12-14
DE2919593C2 (fr) 1990-12-06
GB2020552B (en) 1982-10-20
US4237167A (en) 1980-12-02
JPS54151130A (en) 1979-11-28
GB2020550B (en) 1982-12-15
GB2020550A (en) 1979-11-21
DE2919543A1 (de) 1979-11-22
JPH0530809B2 (fr) 1993-05-11
CA1135626A (fr) 1982-11-16
CH642550A5 (it) 1984-04-30
NL7903824A (nl) 1979-11-19
NL7903823A (nl) 1979-11-19
IT7849355A0 (it) 1978-05-15
IT1156741B (it) 1987-02-04
DK198179A (da) 1979-11-16
FR2425854B1 (fr) 1983-08-05
US4272549A (en) 1981-06-09
IE48122B1 (en) 1984-10-03
DK198279A (da) 1979-11-16
BE876263A (fr) 1979-09-03
CA1134274A (fr) 1982-10-26
LU81263A1 (fr) 1979-09-10
IE790951L (en) 1979-11-15
BE876262A (fr) 1979-09-03
IL57265A0 (en) 1979-09-30
IE48121B1 (en) 1984-10-03

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