FR2500824B1 - Acide 5,5'-azobis-salicylique et ses sels utiles notamment pour le traitement des affections inflammatoires de l'intestin - Google Patents

Acide 5,5'-azobis-salicylique et ses sels utiles notamment pour le traitement des affections inflammatoires de l'intestin

Info

Publication number
FR2500824B1
FR2500824B1 FR8123969A FR8123969A FR2500824B1 FR 2500824 B1 FR2500824 B1 FR 2500824B1 FR 8123969 A FR8123969 A FR 8123969A FR 8123969 A FR8123969 A FR 8123969A FR 2500824 B1 FR2500824 B1 FR 2500824B1
Authority
FR
France
Prior art keywords
azobis
treatment
salicylic acid
salts useful
inflammatory intestinal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8123969A
Other languages
English (en)
Other versions
FR2500824A1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Health AB
Original Assignee
Pharmacia AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia AB filed Critical Pharmacia AB
Publication of FR2500824A1 publication Critical patent/FR2500824A1/fr
Application granted granted Critical
Publication of FR2500824B1 publication Critical patent/FR2500824B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C245/00—Compounds containing chains of at least two nitrogen atoms with at least one nitrogen-to-nitrogen multiple bond
    • C07C245/02—Azo compounds, i.e. compounds having the free valencies of —N=N— groups attached to different atoms, e.g. diazohydroxides
    • C07C245/06—Azo compounds, i.e. compounds having the free valencies of —N=N— groups attached to different atoms, e.g. diazohydroxides with nitrogen atoms of azo groups bound to carbon atoms of six-membered aromatic rings
    • C07C245/08—Azo compounds, i.e. compounds having the free valencies of —N=N— groups attached to different atoms, e.g. diazohydroxides with nitrogen atoms of azo groups bound to carbon atoms of six-membered aromatic rings with the two nitrogen atoms of azo groups bound to carbon atoms of six-membered aromatic rings, e.g. azobenzene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B63/00—Lakes
    • C09B63/005—Metal lakes of dyes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FR8123969A 1981-03-02 1981-12-22 Acide 5,5'-azobis-salicylique et ses sels utiles notamment pour le traitement des affections inflammatoires de l'intestin Expired FR2500824B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/239,813 US4312806A (en) 1981-03-02 1981-03-02 Method and compounds for treating inflammatory bowel disease

Publications (2)

Publication Number Publication Date
FR2500824A1 FR2500824A1 (fr) 1982-09-03
FR2500824B1 true FR2500824B1 (fr) 1985-07-19

Family

ID=22903854

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8123969A Expired FR2500824B1 (fr) 1981-03-02 1981-12-22 Acide 5,5'-azobis-salicylique et ses sels utiles notamment pour le traitement des affections inflammatoires de l'intestin

Country Status (23)

Country Link
US (1) US4312806A (fr)
JP (1) JPS57144219A (fr)
AT (1) AT375637B (fr)
AU (1) AU545804B2 (fr)
BE (1) BE891583A (fr)
CA (1) CA1167031A (fr)
CH (1) CH647409A5 (fr)
DE (1) DE3149359A1 (fr)
DK (1) DK540581A (fr)
ES (1) ES507811A0 (fr)
FI (1) FI813919L (fr)
FR (1) FR2500824B1 (fr)
GB (1) GB2093833B (fr)
GR (1) GR76684B (fr)
IE (1) IE52898B1 (fr)
IL (1) IL64459A0 (fr)
IT (1) IT1147821B (fr)
NL (1) NL8105824A (fr)
NO (1) NO153099C (fr)
NZ (1) NZ199273A (fr)
PH (1) PH17040A (fr)
SE (1) SE8107292L (fr)
ZA (1) ZA818507B (fr)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4960765A (en) * 1980-03-20 1990-10-02 Farmaceutisk Laboratorium Ferring A/S Pharmaceutical composition and method for the treatment of colitis ulcerosa and Crohn's disease by oral administration
JPS57500432A (fr) * 1980-03-20 1982-03-11
SE8002322L (sv) * 1980-03-26 1981-09-27 Pharmacia Ab Medel for behandling av inflammatoriska tarmsjukdomar
DE3151196A1 (de) * 1981-12-23 1983-06-30 Kurt Heinz Prof. Dr. 7800 Freiburg Bauer Verfahren zur herstellung von gut loeslichen 5-aminosalicylsaeure-arzneimittelzubereitungen
SE8303399D0 (sv) * 1983-06-15 1983-06-15 Pharmacia Ab Azo-bis-salicyl syra och salt derav, deras farmaceutiska beredning samt framstellning av syran
SE8303400D0 (sv) * 1983-06-15 1983-06-15 Pharmacia Ab Azo-bis-salicylsyra och salt derav samt deras farmaceutiska beredning och anvendning
SE8405924L (sv) * 1984-11-23 1986-05-24 Pharmacia Ab Nya azoforeningar
US5120306A (en) * 1990-03-21 1992-06-09 Gosselin Leon F Direct delivery of anti-inflammatories to the proximal small bowel
ES2104513B1 (es) * 1995-10-11 1998-07-01 Uriach & Cia Sa J Nuevos derivados del acido 5-aminosalicilico.
DK0790998T3 (da) * 1995-09-08 2001-02-05 Uriach & Cia Sa J Azo-derivater af 5-aminosalicylsyre til behandling af inflammatorisk tarmsygdom
ES2106682B1 (es) * 1995-09-08 1998-07-01 Uriach & Cia Sa J Nuevos derivados azo del acido 5-aminosalicilico.
US6989377B2 (en) 1999-12-21 2006-01-24 Wisconsin Alumni Research Foundation Treating vitamin D responsive diseases
US6358939B1 (en) 1999-12-21 2002-03-19 Northern Lights Pharmaceuticals, Llc Use of biologically active vitamin D compounds for the prevention and treatment of inflammatory bowel disease
ES2165803B1 (es) 2000-04-10 2003-09-16 Uriach & Cia Sa J Nueva sal de un derivado azo del acido 5-aminosalicilico
CA2359812C (fr) 2000-11-20 2004-02-10 The Procter & Gamble Company Formes posologiques pharmaceutiques a couches multiples permettant de reduire l'impact des revetement fractures
WO2005070963A1 (fr) 2004-01-12 2005-08-04 Applied Molecular Evolution, Inc Variants de la region fc
WO2010042933A2 (fr) 2008-10-10 2010-04-15 Northwestern University Inhibition et traitement des métastases du cancer de la prostate
WO2016073897A1 (fr) 2014-11-06 2016-05-12 Northwestern University Inhibition de la motilité de cellules cancéreuses
CN105985259B (zh) * 2015-02-04 2018-07-27 中国科学院化学研究所 偶氮苯甲酸类化合物及其制备方法和应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1157169A (en) * 1914-11-03 1915-10-19 Geigy Ag J R Mordant-dyeing azo dye.
GB408676A (en) * 1931-10-17 1934-04-16 Ig Farbenindustrie Ag The manufacture of symmetrically substituted azobenzene compounds
US2894984A (en) * 1958-05-15 1959-07-14 Pennsalt Chemicals Corp 4-trifluoromethyl salicylic acids and their preparation
US3413225A (en) * 1966-06-27 1968-11-26 Monsanto Co Functional fluid containing azo benzene derivatives as antioxidants
US3674844A (en) * 1970-04-20 1972-07-04 Merck & Co Inc Salicylic acid derivatives
US4190716A (en) * 1978-12-20 1980-02-26 Dynapol Polymeric agent for releasing 5-aminosalicylic acid or its salts into the gastrointestinal tract
SE8002322L (sv) * 1980-03-26 1981-09-27 Pharmacia Ab Medel for behandling av inflammatoriska tarmsjukdomar

Also Published As

Publication number Publication date
DE3149359A1 (de) 1982-09-16
ES8500894A1 (es) 1984-11-01
NZ199273A (en) 1985-03-20
AU7828681A (en) 1982-09-09
GB2093833B (en) 1985-01-23
NO153099B (no) 1985-10-07
IE52898B1 (en) 1988-04-13
GR76684B (fr) 1984-08-24
IE813104L (en) 1982-09-02
IT1147821B (it) 1986-11-26
BE891583A (fr) 1982-06-22
NO153099C (no) 1986-01-15
FR2500824A1 (fr) 1982-09-03
AT375637B (de) 1984-08-27
US4312806A (en) 1982-01-26
IT8247894A0 (it) 1982-03-02
IL64459A0 (en) 1982-03-31
NL8105824A (nl) 1982-10-01
SE8107292L (sv) 1982-09-03
ZA818507B (en) 1983-07-27
CH647409A5 (de) 1985-01-31
ES507811A0 (es) 1984-11-01
GB2093833A (en) 1982-09-08
PH17040A (en) 1984-05-17
JPS57144219A (en) 1982-09-06
FI813919L (fi) 1982-09-03
DK540581A (da) 1982-09-03
ATA540681A (de) 1984-01-15
AU545804B2 (en) 1985-08-01
CA1167031A (fr) 1984-05-08
NO814424L (no) 1982-09-03

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Legal Events

Date Code Title Description
TP Transmission of property
ST Notification of lapse