ES8500894A1 - Procedimiento para preparar sales de acido 5,5'-azobis-salicico. - Google Patents

Procedimiento para preparar sales de acido 5,5'-azobis-salicico.

Info

Publication number
ES8500894A1
ES8500894A1 ES507811A ES507811A ES8500894A1 ES 8500894 A1 ES8500894 A1 ES 8500894A1 ES 507811 A ES507811 A ES 507811A ES 507811 A ES507811 A ES 507811A ES 8500894 A1 ES8500894 A1 ES 8500894A1
Authority
ES
Spain
Prior art keywords
inflammatory bowel
bowel disease
compounds
treating inflammatory
ibd
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES507811A
Other languages
English (en)
Other versions
ES507811A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GD Searle LLC
Original Assignee
GD Searle LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GD Searle LLC filed Critical GD Searle LLC
Publication of ES507811A0 publication Critical patent/ES507811A0/es
Publication of ES8500894A1 publication Critical patent/ES8500894A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C245/00—Compounds containing chains of at least two nitrogen atoms with at least one nitrogen-to-nitrogen multiple bond
    • C07C245/02—Azo compounds, i.e. compounds having the free valencies of —N=N— groups attached to different atoms, e.g. diazohydroxides
    • C07C245/06—Azo compounds, i.e. compounds having the free valencies of —N=N— groups attached to different atoms, e.g. diazohydroxides with nitrogen atoms of azo groups bound to carbon atoms of six-membered aromatic rings
    • C07C245/08—Azo compounds, i.e. compounds having the free valencies of —N=N— groups attached to different atoms, e.g. diazohydroxides with nitrogen atoms of azo groups bound to carbon atoms of six-membered aromatic rings with the two nitrogen atoms of azo groups bound to carbon atoms of six-membered aromatic rings, e.g. azobenzene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B63/00—Lakes
    • C09B63/005—Metal lakes of dyes

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR SALES DE ACIDO 5,5-AZOBIS-SALICILICO, DE FORMULA GENERAL (I), EN LA QUE M ES UN METAL ALCALINOTERREO DIVALENTE.CONSISTE EN HACER REACCIONAR UN ACIDO 5,5-AZOBIS-SALICILICO, DE FORMULA GENERAL (II), CON UN OXIDO O HIDROXIDO DE METAL ALCALINOTERREO DIVALENTE, A TEMPERATURA DE REFLUJO.DE APLICACION EN EL TRATAMIENTO DE ENFERMEDADES INFLAMATORIAS DEL INTESTINO.
ES507811A 1981-03-02 1981-12-09 Procedimiento para preparar sales de acido 5,5'-azobis-salicico. Expired ES8500894A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/239,813 US4312806A (en) 1981-03-02 1981-03-02 Method and compounds for treating inflammatory bowel disease

Publications (2)

Publication Number Publication Date
ES507811A0 ES507811A0 (es) 1984-11-01
ES8500894A1 true ES8500894A1 (es) 1984-11-01

Family

ID=22903854

Family Applications (1)

Application Number Title Priority Date Filing Date
ES507811A Expired ES8500894A1 (es) 1981-03-02 1981-12-09 Procedimiento para preparar sales de acido 5,5'-azobis-salicico.

Country Status (23)

Country Link
US (1) US4312806A (es)
JP (1) JPS57144219A (es)
AT (1) AT375637B (es)
AU (1) AU545804B2 (es)
BE (1) BE891583A (es)
CA (1) CA1167031A (es)
CH (1) CH647409A5 (es)
DE (1) DE3149359A1 (es)
DK (1) DK540581A (es)
ES (1) ES8500894A1 (es)
FI (1) FI813919L (es)
FR (1) FR2500824B1 (es)
GB (1) GB2093833B (es)
GR (1) GR76684B (es)
IE (1) IE52898B1 (es)
IL (1) IL64459A0 (es)
IT (1) IT1147821B (es)
NL (1) NL8105824A (es)
NO (1) NO153099C (es)
NZ (1) NZ199273A (es)
PH (1) PH17040A (es)
SE (1) SE8107292L (es)
ZA (1) ZA818507B (es)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4960765A (en) * 1980-03-20 1990-10-02 Farmaceutisk Laboratorium Ferring A/S Pharmaceutical composition and method for the treatment of colitis ulcerosa and Crohn's disease by oral administration
JPS57500432A (es) * 1980-03-20 1982-03-11
SE8002322L (sv) * 1980-03-26 1981-09-27 Pharmacia Ab Medel for behandling av inflammatoriska tarmsjukdomar
DE3151196A1 (de) * 1981-12-23 1983-06-30 Kurt Heinz Prof. Dr. 7800 Freiburg Bauer Verfahren zur herstellung von gut loeslichen 5-aminosalicylsaeure-arzneimittelzubereitungen
SE8303399D0 (sv) * 1983-06-15 1983-06-15 Pharmacia Ab Azo-bis-salicyl syra och salt derav, deras farmaceutiska beredning samt framstellning av syran
SE8303400D0 (sv) * 1983-06-15 1983-06-15 Pharmacia Ab Azo-bis-salicylsyra och salt derav samt deras farmaceutiska beredning och anvendning
SE8405924L (sv) * 1984-11-23 1986-05-24 Pharmacia Ab Nya azoforeningar
US5120306A (en) * 1990-03-21 1992-06-09 Gosselin Leon F Direct delivery of anti-inflammatories to the proximal small bowel
ES2106682B1 (es) * 1995-09-08 1998-07-01 Uriach & Cia Sa J Nuevos derivados azo del acido 5-aminosalicilico.
ES2104513B1 (es) * 1995-10-11 1998-07-01 Uriach & Cia Sa J Nuevos derivados del acido 5-aminosalicilico.
PT790998E (pt) * 1995-09-08 2001-04-30 Uriach & Cia Sa J Derivados azo do acido 5-aminosalicilico para o tratamento da doenca inflamatoria dos intestinos
US6358939B1 (en) 1999-12-21 2002-03-19 Northern Lights Pharmaceuticals, Llc Use of biologically active vitamin D compounds for the prevention and treatment of inflammatory bowel disease
US6989377B2 (en) 1999-12-21 2006-01-24 Wisconsin Alumni Research Foundation Treating vitamin D responsive diseases
ES2165803B1 (es) * 2000-04-10 2003-09-16 Uriach & Cia Sa J Nueva sal de un derivado azo del acido 5-aminosalicilico
CA2359812C (en) 2000-11-20 2004-02-10 The Procter & Gamble Company Pharmaceutical dosage form with multiple coatings for reduced impact of coating fractures
CN1918178B (zh) 2004-01-12 2012-08-22 应用分子进化公司 Fc区变体
WO2010042933A2 (en) 2008-10-10 2010-04-15 Northwestern University Inhibition and treatment of prostate cancer metastasis
US9839625B2 (en) 2014-11-06 2017-12-12 Northwestern University Inhibition of cancer cell motility
CN105985259B (zh) * 2015-02-04 2018-07-27 中国科学院化学研究所 偶氮苯甲酸类化合物及其制备方法和应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1157169A (en) * 1914-11-03 1915-10-19 Geigy Ag J R Mordant-dyeing azo dye.
GB408676A (en) * 1931-10-17 1934-04-16 Ig Farbenindustrie Ag The manufacture of symmetrically substituted azobenzene compounds
US2894984A (en) * 1958-05-15 1959-07-14 Pennsalt Chemicals Corp 4-trifluoromethyl salicylic acids and their preparation
US3413225A (en) * 1966-06-27 1968-11-26 Monsanto Co Functional fluid containing azo benzene derivatives as antioxidants
US3674844A (en) * 1970-04-20 1972-07-04 Merck & Co Inc Salicylic acid derivatives
US4190716A (en) * 1978-12-20 1980-02-26 Dynapol Polymeric agent for releasing 5-aminosalicylic acid or its salts into the gastrointestinal tract
SE8002322L (sv) * 1980-03-26 1981-09-27 Pharmacia Ab Medel for behandling av inflammatoriska tarmsjukdomar

Also Published As

Publication number Publication date
IT8247894A0 (it) 1982-03-02
ZA818507B (en) 1983-07-27
AU7828681A (en) 1982-09-09
NO153099C (no) 1986-01-15
GB2093833A (en) 1982-09-08
PH17040A (en) 1984-05-17
ATA540681A (de) 1984-01-15
ES507811A0 (es) 1984-11-01
GB2093833B (en) 1985-01-23
AT375637B (de) 1984-08-27
SE8107292L (sv) 1982-09-03
CH647409A5 (de) 1985-01-31
AU545804B2 (en) 1985-08-01
IE813104L (en) 1982-09-02
JPS57144219A (en) 1982-09-06
FI813919L (fi) 1982-09-03
NZ199273A (en) 1985-03-20
GR76684B (es) 1984-08-24
IE52898B1 (en) 1988-04-13
FR2500824B1 (fr) 1985-07-19
IT1147821B (it) 1986-11-26
NO814424L (no) 1982-09-03
US4312806A (en) 1982-01-26
BE891583A (fr) 1982-06-22
IL64459A0 (en) 1982-03-31
FR2500824A1 (fr) 1982-09-03
DE3149359A1 (de) 1982-09-16
CA1167031A (en) 1984-05-08
NO153099B (no) 1985-10-07
DK540581A (da) 1982-09-03
NL8105824A (nl) 1982-10-01

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19971001