IT1208753B - L-amminoacil derivati della l-carnitina, procedimento per la loro preparazione e composizioni farmaceutiche ad attivita' epatoprotettrice che li contengono - Google Patents

L-amminoacil derivati della l-carnitina, procedimento per la loro preparazione e composizioni farmaceutiche ad attivita' epatoprotettrice che li contengono

Info

Publication number
IT1208753B
IT1208753B IT8648217A IT4821786A IT1208753B IT 1208753 B IT1208753 B IT 1208753B IT 8648217 A IT8648217 A IT 8648217A IT 4821786 A IT4821786 A IT 4821786A IT 1208753 B IT1208753 B IT 1208753B
Authority
IT
Italy
Prior art keywords
carnitine
procedure
contain
preparation
pharmaceutical compositions
Prior art date
Application number
IT8648217A
Other languages
English (en)
Other versions
IT8648217A0 (it
Inventor
Tinti Maria Ornella
Bagolini Carlo
Misiti Domenico
Scolastico Carlo
Original Assignee
Sigma Tau Ind Farmaceuti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Ind Farmaceuti filed Critical Sigma Tau Ind Farmaceuti
Priority to IT8648217A priority Critical patent/IT1208753B/it
Publication of IT8648217A0 publication Critical patent/IT8648217A0/it
Priority to US07/067,694 priority patent/US4812478A/en
Priority to AT87830245T priority patent/ATE77366T1/de
Priority to ES198787830245T priority patent/ES2039476T3/es
Priority to EP87830245A priority patent/EP0252030B1/en
Priority to DE8787830245T priority patent/DE3779819T2/de
Priority to US07/268,751 priority patent/US4868211A/en
Application granted granted Critical
Publication of IT1208753B publication Critical patent/IT1208753B/it
Priority to GR920401326T priority patent/GR3004990T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
    • C07C279/14—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by carboxyl groups
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IT8648217A 1986-07-02 1986-07-02 L-amminoacil derivati della l-carnitina, procedimento per la loro preparazione e composizioni farmaceutiche ad attivita' epatoprotettrice che li contengono IT1208753B (it)

Priority Applications (8)

Application Number Priority Date Filing Date Title
IT8648217A IT1208753B (it) 1986-07-02 1986-07-02 L-amminoacil derivati della l-carnitina, procedimento per la loro preparazione e composizioni farmaceutiche ad attivita' epatoprotettrice che li contengono
US07/067,694 US4812478A (en) 1986-07-02 1987-06-29 Derivatives of L-amino acyl L-carnitine, process for their preparation and pharmaceutical compositions having hepatoprotecting activity containing same
AT87830245T ATE77366T1 (de) 1986-07-02 1987-07-01 L-amino-acyl l-carnitine, herstellungsverfahren und sie enthaltende arzneimittel mit leberschuetzender wirkung.
ES198787830245T ES2039476T3 (es) 1986-07-02 1987-07-01 Procedimiento para la preparacion de derivados de l-amino acil l-carnitina con actividad hepatoprotectora.
EP87830245A EP0252030B1 (en) 1986-07-02 1987-07-01 Derivatives of l-amino acyl l-carnitine, process for their preparation and pharmaceutical compositions having hepatoprotecting activity containing same
DE8787830245T DE3779819T2 (de) 1986-07-02 1987-07-01 L-amino-acyl l-carnitine, herstellungsverfahren und sie enthaltende arzneimittel mit leberschuetzender wirkung.
US07/268,751 US4868211A (en) 1986-07-02 1988-11-08 Derivatives of L-amino acyl L-carnitine, process for their preparation pharmaceutical compositions having hepatoprotecting activity containing same
GR920401326T GR3004990T3 (it) 1986-07-02 1992-06-19

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8648217A IT1208753B (it) 1986-07-02 1986-07-02 L-amminoacil derivati della l-carnitina, procedimento per la loro preparazione e composizioni farmaceutiche ad attivita' epatoprotettrice che li contengono

Publications (2)

Publication Number Publication Date
IT8648217A0 IT8648217A0 (it) 1986-07-02
IT1208753B true IT1208753B (it) 1989-07-10

Family

ID=11265298

Family Applications (1)

Application Number Title Priority Date Filing Date
IT8648217A IT1208753B (it) 1986-07-02 1986-07-02 L-amminoacil derivati della l-carnitina, procedimento per la loro preparazione e composizioni farmaceutiche ad attivita' epatoprotettrice che li contengono

Country Status (7)

Country Link
US (2) US4812478A (it)
EP (1) EP0252030B1 (it)
AT (1) ATE77366T1 (it)
DE (1) DE3779819T2 (it)
ES (1) ES2039476T3 (it)
GR (1) GR3004990T3 (it)
IT (1) IT1208753B (it)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1224842B (it) * 1988-12-27 1990-10-24 Sigma Tau Ind Farmaceuti Uso di derivati della l-carnitina nel trattamento terapeutico delle alterazioni degenerative del sistema nervoso
IT1240790B (it) * 1990-03-06 1993-12-17 Sigma Tau Ind Farmaceuti Alfa-ammino-omega-alchiltioacilcarnitine e composizioni farmaceutiche contenenti tali composti ad attivita' sul sistema cardiovascolare.
IT1248321B (it) * 1991-05-15 1995-01-05 Sigma Tau Ind Farmaceuti Uso di esteri di acil l-carnitine con l'acido gamma-idrossibutirrico per produrre composizioni farmaceutiche per il trattamento di epatopatie
US5569457A (en) * 1994-11-18 1996-10-29 Shug; Austin L. Method of stimulating antibody formation

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1156840B (it) * 1978-06-27 1987-02-04 Sigma Tau Ind Farmaceuti Acil derivati della carnitina
IT1145371B (it) * 1980-05-30 1986-11-05 Sigma Tau Ind Farmaceuti Alcossi-acil carnitine procedimento per la loro preparazione e composizioni farmaceutiche che le contengono
EP0150688B1 (en) * 1983-12-28 1987-04-22 Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. Salts of l-carnitine and alkanoyl l-carnitines and process for preparing same
IT1181682B (it) * 1985-06-11 1987-09-30 Sigma Tau Ind Farmaceuti Impiego di alcanoil l-carnitine per il trattamento terapeutico del parkinsonismo idiopatico o indotto

Also Published As

Publication number Publication date
EP0252030A2 (en) 1988-01-07
ATE77366T1 (de) 1992-07-15
DE3779819T2 (de) 1992-12-24
EP0252030A3 (en) 1988-11-02
US4868211A (en) 1989-09-19
US4812478A (en) 1989-03-14
EP0252030B1 (en) 1992-06-17
IT8648217A0 (it) 1986-07-02
ES2039476T3 (es) 1993-10-01
DE3779819D1 (de) 1992-07-23
GR3004990T3 (it) 1993-04-28

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Legal Events

Date Code Title Description
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19950616