DE3779819D1 - L-amino-acyl l-carnitine, herstellungsverfahren und sie enthaltende arzneimittel mit leberschuetzender wirkung. - Google Patents

L-amino-acyl l-carnitine, herstellungsverfahren und sie enthaltende arzneimittel mit leberschuetzender wirkung.

Info

Publication number
DE3779819D1
DE3779819D1 DE8787830245T DE3779819T DE3779819D1 DE 3779819 D1 DE3779819 D1 DE 3779819D1 DE 8787830245 T DE8787830245 T DE 8787830245T DE 3779819 T DE3779819 T DE 3779819T DE 3779819 D1 DE3779819 D1 DE 3779819D1
Authority
DE
Germany
Prior art keywords
carnitine
acyl
liver
amino
production method
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8787830245T
Other languages
English (en)
Other versions
DE3779819T2 (de
Inventor
Maria Ornella Tinti
Carlo Alberto Bagolini
Domenico Misiti
Carlo Scolastico
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sigma Tau Industrie Farmaceutiche Riunite SpA
Original Assignee
Sigma Tau Industrie Farmaceutiche Riunite SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Industrie Farmaceutiche Riunite SpA filed Critical Sigma Tau Industrie Farmaceutiche Riunite SpA
Publication of DE3779819D1 publication Critical patent/DE3779819D1/de
Application granted granted Critical
Publication of DE3779819T2 publication Critical patent/DE3779819T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
    • C07C279/14—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by carboxyl groups
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE8787830245T 1986-07-02 1987-07-01 L-amino-acyl l-carnitine, herstellungsverfahren und sie enthaltende arzneimittel mit leberschuetzender wirkung. Expired - Fee Related DE3779819T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8648217A IT1208753B (it) 1986-07-02 1986-07-02 L-amminoacil derivati della l-carnitina, procedimento per la loro preparazione e composizioni farmaceutiche ad attivita' epatoprotettrice che li contengono

Publications (2)

Publication Number Publication Date
DE3779819D1 true DE3779819D1 (de) 1992-07-23
DE3779819T2 DE3779819T2 (de) 1992-12-24

Family

ID=11265298

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8787830245T Expired - Fee Related DE3779819T2 (de) 1986-07-02 1987-07-01 L-amino-acyl l-carnitine, herstellungsverfahren und sie enthaltende arzneimittel mit leberschuetzender wirkung.

Country Status (7)

Country Link
US (2) US4812478A (de)
EP (1) EP0252030B1 (de)
AT (1) ATE77366T1 (de)
DE (1) DE3779819T2 (de)
ES (1) ES2039476T3 (de)
GR (1) GR3004990T3 (de)
IT (1) IT1208753B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1224842B (it) * 1988-12-27 1990-10-24 Sigma Tau Ind Farmaceuti Uso di derivati della l-carnitina nel trattamento terapeutico delle alterazioni degenerative del sistema nervoso
IT1240790B (it) * 1990-03-06 1993-12-17 Sigma Tau Ind Farmaceuti Alfa-ammino-omega-alchiltioacilcarnitine e composizioni farmaceutiche contenenti tali composti ad attivita' sul sistema cardiovascolare.
IT1248321B (it) * 1991-05-15 1995-01-05 Sigma Tau Ind Farmaceuti Uso di esteri di acil l-carnitine con l'acido gamma-idrossibutirrico per produrre composizioni farmaceutiche per il trattamento di epatopatie
US5569457A (en) * 1994-11-18 1996-10-29 Shug; Austin L. Method of stimulating antibody formation

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1156840B (it) * 1978-06-27 1987-02-04 Sigma Tau Ind Farmaceuti Acil derivati della carnitina
IT1145371B (it) * 1980-05-30 1986-11-05 Sigma Tau Ind Farmaceuti Alcossi-acil carnitine procedimento per la loro preparazione e composizioni farmaceutiche che le contengono
DE3463261D1 (en) * 1983-12-28 1987-05-27 Sigma Tau Ind Farmaceuti Salts of l-carnitine and alkanoyl l-carnitines and process for preparing same
IT1181682B (it) * 1985-06-11 1987-09-30 Sigma Tau Ind Farmaceuti Impiego di alcanoil l-carnitine per il trattamento terapeutico del parkinsonismo idiopatico o indotto

Also Published As

Publication number Publication date
ES2039476T3 (es) 1993-10-01
IT8648217A0 (it) 1986-07-02
US4868211A (en) 1989-09-19
EP0252030A2 (de) 1988-01-07
DE3779819T2 (de) 1992-12-24
EP0252030B1 (de) 1992-06-17
EP0252030A3 (en) 1988-11-02
US4812478A (en) 1989-03-14
GR3004990T3 (de) 1993-04-28
IT1208753B (it) 1989-07-10
ATE77366T1 (de) 1992-07-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee