ATE77366T1 - L-amino-acyl l-carnitine, herstellungsverfahren und sie enthaltende arzneimittel mit leberschuetzender wirkung. - Google Patents

L-amino-acyl l-carnitine, herstellungsverfahren und sie enthaltende arzneimittel mit leberschuetzender wirkung.

Info

Publication number
ATE77366T1
ATE77366T1 AT87830245T AT87830245T ATE77366T1 AT E77366 T1 ATE77366 T1 AT E77366T1 AT 87830245 T AT87830245 T AT 87830245T AT 87830245 T AT87830245 T AT 87830245T AT E77366 T1 ATE77366 T1 AT E77366T1
Authority
AT
Austria
Prior art keywords
carnitine
acyl
amino
production process
protective effects
Prior art date
Application number
AT87830245T
Other languages
English (en)
Inventor
Maria Ornella Tinti
Carlo Alberto Bagolini
Domenico Misiti
Carlo Scolastico
Original Assignee
Sigma Tau Ind Farmaceuti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Ind Farmaceuti filed Critical Sigma Tau Ind Farmaceuti
Application granted granted Critical
Publication of ATE77366T1 publication Critical patent/ATE77366T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
    • C07C279/14—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by carboxyl groups
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT87830245T 1986-07-02 1987-07-01 L-amino-acyl l-carnitine, herstellungsverfahren und sie enthaltende arzneimittel mit leberschuetzender wirkung. ATE77366T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT8648217A IT1208753B (it) 1986-07-02 1986-07-02 L-amminoacil derivati della l-carnitina, procedimento per la loro preparazione e composizioni farmaceutiche ad attivita' epatoprotettrice che li contengono
EP87830245A EP0252030B1 (de) 1986-07-02 1987-07-01 L-amino-acyl L-carnitine, Herstellungsverfahren und sie enthaltende Arzneimittel mit leberschützender Wirkung

Publications (1)

Publication Number Publication Date
ATE77366T1 true ATE77366T1 (de) 1992-07-15

Family

ID=11265298

Family Applications (1)

Application Number Title Priority Date Filing Date
AT87830245T ATE77366T1 (de) 1986-07-02 1987-07-01 L-amino-acyl l-carnitine, herstellungsverfahren und sie enthaltende arzneimittel mit leberschuetzender wirkung.

Country Status (7)

Country Link
US (2) US4812478A (de)
EP (1) EP0252030B1 (de)
AT (1) ATE77366T1 (de)
DE (1) DE3779819T2 (de)
ES (1) ES2039476T3 (de)
GR (1) GR3004990T3 (de)
IT (1) IT1208753B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1224842B (it) * 1988-12-27 1990-10-24 Sigma Tau Ind Farmaceuti Uso di derivati della l-carnitina nel trattamento terapeutico delle alterazioni degenerative del sistema nervoso
IT1240790B (it) * 1990-03-06 1993-12-17 Sigma Tau Ind Farmaceuti Alfa-ammino-omega-alchiltioacilcarnitine e composizioni farmaceutiche contenenti tali composti ad attivita' sul sistema cardiovascolare.
IT1248321B (it) * 1991-05-15 1995-01-05 Sigma Tau Ind Farmaceuti Uso di esteri di acil l-carnitine con l'acido gamma-idrossibutirrico per produrre composizioni farmaceutiche per il trattamento di epatopatie
US5569457A (en) * 1994-11-18 1996-10-29 Shug; Austin L. Method of stimulating antibody formation

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1156840B (it) * 1978-06-27 1987-02-04 Sigma Tau Ind Farmaceuti Acil derivati della carnitina
IT1145371B (it) * 1980-05-30 1986-11-05 Sigma Tau Ind Farmaceuti Alcossi-acil carnitine procedimento per la loro preparazione e composizioni farmaceutiche che le contengono
EP0150688B1 (de) * 1983-12-28 1987-04-22 Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. Salze von L-Carnitin und Alkanoyl-L-Carnitinen sowie Verfahren zur Herstellung derselben
IT1181682B (it) * 1985-06-11 1987-09-30 Sigma Tau Ind Farmaceuti Impiego di alcanoil l-carnitine per il trattamento terapeutico del parkinsonismo idiopatico o indotto

Also Published As

Publication number Publication date
ES2039476T3 (es) 1993-10-01
EP0252030B1 (de) 1992-06-17
GR3004990T3 (de) 1993-04-28
US4868211A (en) 1989-09-19
US4812478A (en) 1989-03-14
IT1208753B (it) 1989-07-10
IT8648217A0 (it) 1986-07-02
DE3779819T2 (de) 1992-12-24
EP0252030A3 (en) 1988-11-02
EP0252030A2 (de) 1988-01-07
DE3779819D1 (de) 1992-07-23

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee