IT1295408B1 - Associazione di l-carnitina e alcanoil l-carnitine per il trattamento dell'alcoolismo - Google Patents
Associazione di l-carnitina e alcanoil l-carnitine per il trattamento dell'alcoolismoInfo
- Publication number
- IT1295408B1 IT1295408B1 IT97RM000594A ITRM970594A IT1295408B1 IT 1295408 B1 IT1295408 B1 IT 1295408B1 IT 97RM000594 A IT97RM000594 A IT 97RM000594A IT RM970594 A ITRM970594 A IT RM970594A IT 1295408 B1 IT1295408 B1 IT 1295408B1
- Authority
- IT
- Italy
- Prior art keywords
- carnitine
- alcanoyl
- alcoholism
- association
- treatment
- Prior art date
Links
- PHIQHXFUZVPYII-ZCFIWIBFSA-N (R)-carnitine Chemical compound C[N+](C)(C)C[C@H](O)CC([O-])=O PHIQHXFUZVPYII-ZCFIWIBFSA-N 0.000 title abstract 3
- 208000007848 Alcoholism Diseases 0.000 title 1
- 201000007930 alcohol dependence Diseases 0.000 title 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- RDHQFKQIGNGIED-MRVPVSSYSA-N O-acetyl-L-carnitine Chemical compound CC(=O)O[C@H](CC([O-])=O)C[N+](C)(C)C RDHQFKQIGNGIED-MRVPVSSYSA-N 0.000 abstract 1
- UFAHZIUFPNSHSL-MRVPVSSYSA-N O-propanoyl-L-carnitine Chemical compound CCC(=O)O[C@H](CC([O-])=O)C[N+](C)(C)C UFAHZIUFPNSHSL-MRVPVSSYSA-N 0.000 abstract 1
- 208000007271 Substance Withdrawal Syndrome Diseases 0.000 abstract 1
- 235000019788 craving Nutrition 0.000 abstract 1
- 235000015872 dietary supplement Nutrition 0.000 abstract 1
- 235000013305 food Nutrition 0.000 abstract 1
- 235000013402 health food Nutrition 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000002417 nutraceutical Substances 0.000 abstract 1
- 235000021436 nutraceutical agent Nutrition 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/175—Amino acids
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/15—Vitamins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Priority Applications (30)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT97RM000594A IT1295408B1 (it) | 1997-10-03 | 1997-10-03 | Associazione di l-carnitina e alcanoil l-carnitine per il trattamento dell'alcoolismo |
EA200000377A EA002177B1 (ru) | 1997-10-03 | 1998-09-18 | Композиция для подавления симптомов абстиненции и тяги к алкоголю у алкоголиков и профилактики злоупотребления алкоголем у здоровых людей |
EEP200000235A EE04036B1 (et) | 1997-10-03 | 1998-09-18 | Kompositsioon alkoholi abstinentsisündroomi ja alkoholihimu mahasurumiseks alkohoolikutel ning alkoholi kuritarvitamise vältimiseks tervetel inimestel |
AU93660/98A AU730740B2 (en) | 1997-10-03 | 1998-09-18 | Composition for suppressing withdrawal symptoms and craving for alcohol in alcoholics and preventing the abuse of alcohol in healthy subjects |
KR1020007003626A KR100560097B1 (ko) | 1997-10-03 | 1998-09-18 | 알콜중독자에게는 알콜 금단(禁斷) 증상과 음주욕구를 억제하고, 그리고 건강한 사람에게는 과음을 예방하는 약제조성물 |
CZ20001207A CZ291801B6 (cs) | 1997-10-03 | 1998-09-18 | Přípravek k potlačení abstinenčních symptomů a chuti alkoholiků na alkohol a předcházení zneužívání alkoholu zdravými jedinci |
US09/509,652 US6255346B1 (en) | 1997-10-03 | 1998-09-18 | Composition for suppressing withdrawal symptoms and craving for alcohol in alcoholics and preventing the abuse of alcohol in healthy subjects |
DK98946703T DK1022960T3 (da) | 1997-10-03 | 1998-09-18 | Præparat til undertrykkelse af abstinenssymptomer og trang til alkohol hos alkoholikere og forebyggelse af alkoholmisbrug hos raske personer |
HU0004336A HUP0004336A3 (en) | 1997-10-03 | 1998-09-18 | Composition for suppressing withdrawal symptoms and craving for alcohol in alcoholics and preventing the abuse of alcohol in healthy subjects |
SI9830131T SI1022960T1 (en) | 1997-10-03 | 1998-09-18 | Composition for suppressing withdrawal symptoms and craving for alcohol in alcoholics and preventing the abuse of alcohol in healthy subjects |
NZ503663A NZ503663A (en) | 1997-10-03 | 1998-09-18 | Composition for suppressing withdrawal symptoms and craving for alcohol in alcoholics and preventing the abuse of alcohol in healthy subjects |
JP2000514534A JP2001518484A (ja) | 1997-10-03 | 1998-09-18 | アルコール中毒者の禁断症状とアルコールに対する渇望を抑制するための、および、健康な人のアルコールの濫用を防ぐための組成物 |
CN98810325A CN1092939C (zh) | 1997-10-03 | 1998-09-18 | 一种抑制酗酒者的脱瘾综合症和饮酒欲望并预防健康人体滥用酒精的组合物 |
SK476-2000A SK283384B6 (sk) | 1997-10-03 | 1998-09-18 | Orálne alebo parenterálne aplikovateľná kompozícia a jej použitie |
PL98339621A PL189663B1 (pl) | 1997-10-03 | 1998-09-18 | Kompozycja i jej zastosowanie do łagodzenia objawów odstawienia alkoholu i głodu alkoholowego i do zapobiegania nadużywaniu alkoholu przez osoby zdrowe |
KR10-2005-7014865A KR100530368B1 (ko) | 1997-10-03 | 1998-09-18 | 알콜중독자에게는 알콜 금단(禁斷) 증상과 음주욕구를억제하고, 그리고 건강한 사람에게는 과음을 예방하는식품조성물 |
AT98946703T ATE220860T1 (de) | 1997-10-03 | 1998-09-18 | Zusammensetzung zur unterdrückung von entzugssymptomen und alkoholabhängigkeit bei alkoholikern sowie prävention von alkoholmissbrauch bei gesunden personen |
DE69806788T DE69806788T2 (de) | 1997-10-03 | 1998-09-18 | Zusammensetzung zur unterdrückung von entzugssymptomen und alkoholabhängigkeit bei alkoholikern sowie prävention von alkoholmissbrauch bei gesunden personen |
ES98946703T ES2180200T3 (es) | 1997-10-03 | 1998-09-18 | Composicion para la supresion de los sintomas de abstinencia y ansia de alcohol en alcoholicos y prevencion del abuso de alcohol en individuos sanos. |
MXPA00003232A MXPA00003232A (es) | 1997-10-03 | 1998-09-18 | Composicion para suprimir sintomas de abandono y deseo de alcohol en alcoholicos e impedir el abuso de alcohol en sujetos saludables. |
PCT/IT1998/000249 WO1999017623A1 (en) | 1997-10-03 | 1998-09-18 | Composition for suppressing withdrawal symptoms and craving for alcohol in alcoholics and preventing the abuse of alcohol in healthy subjects |
BR9812604-0A BR9812604A (pt) | 1997-10-03 | 1998-09-18 | Composição para suprimir os sintomas da retirada e do desejo insaciável pelo álcool em alcoólatras e para evitar o abuso do álcool em indivìduos saudáveis |
CA002305598A CA2305598C (en) | 1997-10-03 | 1998-09-18 | Composition for suppressing withdrawal symptoms and craving for alcohol in alcoholics and preventing the abuse of alcohol in healthy subjects |
PT98946703T PT1022960E (pt) | 1997-10-03 | 1998-09-18 | Composicao para a supressao dos sintomas de abstinencia e da vontade de ingestao de alcool em alcoolicos e para a prevencao do abuso de alcool em individuos saudaveis |
UA2000041867A UA66807C2 (uk) | 1997-10-03 | 1998-09-18 | Композиція для подолання абстинентних симптомів та потягу до алкоголю в алкоголіків та запобігання зловживанням алкоголем у здорових осіб і спосіб її виготовлення (варіанти) |
EP98946703A EP1022960B1 (en) | 1997-10-03 | 1998-09-18 | Composition for suppressing withdrawal symptoms and craving for alcohol in alcoholics and preventing the abuse of alcohol in healthy subjects |
IS5416A IS2234B (is) | 1997-10-03 | 2000-03-24 | Samsetning til að bæla fráhvarfseinkenni og fíkn í áfengi hjá áfengissjúklingum og fyrirbyggja misnotkun áfengis hjá heilbrigðum einstaklingum |
BG104286A BG64363B1 (bg) | 1997-10-03 | 2000-03-30 | Състав за подтискане на симптомите при отказ и непреодолимо желание за алкохол при алкохолици и профилактика на пристрастяването към алкохол при здрави пациенти |
NO20001688A NO20001688L (no) | 1997-10-03 | 2000-03-31 | Preparat for undertrykkelse av abstinenssymptomer og sug etter alkohol hos alkoholikere, og forebyggelse av misbruk av alkohol hos friske personer. |
HK00106847A HK1028714A1 (en) | 1997-10-03 | 2000-10-26 | Composition for suppressing withdrawal symptoms and craving for alcohol in alcoholics and preventing the abuse of alcohol in healthy subjects |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT97RM000594A IT1295408B1 (it) | 1997-10-03 | 1997-10-03 | Associazione di l-carnitina e alcanoil l-carnitine per il trattamento dell'alcoolismo |
Publications (2)
Publication Number | Publication Date |
---|---|
ITRM970594A1 ITRM970594A1 (it) | 1999-04-03 |
IT1295408B1 true IT1295408B1 (it) | 1999-05-12 |
Family
ID=11405277
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT97RM000594A IT1295408B1 (it) | 1997-10-03 | 1997-10-03 | Associazione di l-carnitina e alcanoil l-carnitine per il trattamento dell'alcoolismo |
Country Status (28)
Country | Link |
---|---|
US (1) | US6255346B1 (it) |
EP (1) | EP1022960B1 (it) |
JP (1) | JP2001518484A (it) |
KR (2) | KR100560097B1 (it) |
CN (1) | CN1092939C (it) |
AT (1) | ATE220860T1 (it) |
AU (1) | AU730740B2 (it) |
BG (1) | BG64363B1 (it) |
BR (1) | BR9812604A (it) |
CA (1) | CA2305598C (it) |
CZ (1) | CZ291801B6 (it) |
DE (1) | DE69806788T2 (it) |
DK (1) | DK1022960T3 (it) |
EA (1) | EA002177B1 (it) |
EE (1) | EE04036B1 (it) |
ES (1) | ES2180200T3 (it) |
HK (1) | HK1028714A1 (it) |
HU (1) | HUP0004336A3 (it) |
IS (1) | IS2234B (it) |
IT (1) | IT1295408B1 (it) |
MX (1) | MXPA00003232A (it) |
NO (1) | NO20001688L (it) |
NZ (1) | NZ503663A (it) |
PL (1) | PL189663B1 (it) |
PT (1) | PT1022960E (it) |
SK (1) | SK283384B6 (it) |
UA (1) | UA66807C2 (it) |
WO (1) | WO1999017623A1 (it) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6090848A (en) * | 1997-12-01 | 2000-07-18 | Sigma-Tau Healthscience S.P.A. | Compositions and methods for increasing the concentration and/or motility of spermatozoa in humans |
IT1306179B1 (it) * | 1999-07-28 | 2001-05-30 | Sigma Tau Healthscience Spa | Composizione per la prevenzione e cura delle disfunzioni e patologierenali di tipo tossico e funzionale. |
ITRM20020194A1 (it) | 2002-04-09 | 2003-10-09 | Sigma Tau Healthscience Spa | Composizione utile per aumentare la concentrazione e la motilita' degli spermatozoi e migliorarne la morfologia nell'uomo. |
ITRM20020620A1 (it) * | 2002-12-13 | 2004-06-14 | Sigma Tau Ind Farmaceuti | Uso delle carnitine per la prevenzione e/o il trattamento dei disturbi causati dall'andropausa. |
US7776913B2 (en) | 2002-12-13 | 2010-08-17 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Carnitines for treating or preventing disorders caused by andropause |
CN101766717B (zh) * | 2008-12-31 | 2012-10-10 | 克科 | 解酒醒酒组合物 |
CN101766716B (zh) * | 2008-12-31 | 2012-08-29 | 克科 | 解酒醒酒组合物 |
CN101766715B (zh) * | 2008-12-31 | 2012-08-29 | 克科 | 解酒醒酒组合物 |
CN101766672B (zh) * | 2008-12-31 | 2012-10-10 | 克科 | 解酒醒酒组合物 |
CN101766635B (zh) * | 2008-12-31 | 2012-10-10 | 克科 | 解酒醒酒组合物 |
CN101766637B (zh) * | 2008-12-31 | 2012-08-29 | 克科 | 解酒醒酒组合物 |
CN106176756A (zh) * | 2015-04-30 | 2016-12-07 | 刘力 | 包含手性异构化合物的赖氨酸五维药物组合物及其用途 |
US20230149338A1 (en) * | 2020-04-14 | 2023-05-18 | The Regents Of The University Of California | Diagnosis and treatment of addiction |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1245869B (it) | 1991-06-05 | 1994-10-25 | Sigma Tau Ind Farmaceuti | Impiego di propionil l-carnitina per il recupero del tono muscolare in soggetti immobilizzati |
DE19527281A1 (de) | 1995-07-26 | 1997-01-30 | Hans Guenter Berner Gmbh | Nahrungsergänzungsmittel |
ATE212189T1 (de) * | 1995-12-01 | 2002-02-15 | Unilever Nv | Mikrowellen erhitzbare knusperige brötchen |
DE69605531T2 (de) * | 1996-03-04 | 2000-05-31 | Sigma Tau Ind Farmaceuti | Carnitinderivat als Arzneimittel zur Behandlung von Arteriosklerose obliterans |
-
1997
- 1997-10-03 IT IT97RM000594A patent/IT1295408B1/it active IP Right Grant
-
1998
- 1998-09-18 DE DE69806788T patent/DE69806788T2/de not_active Expired - Fee Related
- 1998-09-18 HU HU0004336A patent/HUP0004336A3/hu unknown
- 1998-09-18 KR KR1020007003626A patent/KR100560097B1/ko not_active IP Right Cessation
- 1998-09-18 WO PCT/IT1998/000249 patent/WO1999017623A1/en active IP Right Grant
- 1998-09-18 MX MXPA00003232A patent/MXPA00003232A/es active IP Right Grant
- 1998-09-18 KR KR10-2005-7014865A patent/KR100530368B1/ko not_active IP Right Cessation
- 1998-09-18 SK SK476-2000A patent/SK283384B6/sk unknown
- 1998-09-18 DK DK98946703T patent/DK1022960T3/da active
- 1998-09-18 CN CN98810325A patent/CN1092939C/zh not_active Expired - Fee Related
- 1998-09-18 EE EEP200000235A patent/EE04036B1/xx not_active IP Right Cessation
- 1998-09-18 CZ CZ20001207A patent/CZ291801B6/cs not_active IP Right Cessation
- 1998-09-18 ES ES98946703T patent/ES2180200T3/es not_active Expired - Lifetime
- 1998-09-18 CA CA002305598A patent/CA2305598C/en not_active Expired - Fee Related
- 1998-09-18 AU AU93660/98A patent/AU730740B2/en not_active Ceased
- 1998-09-18 NZ NZ503663A patent/NZ503663A/en unknown
- 1998-09-18 JP JP2000514534A patent/JP2001518484A/ja active Pending
- 1998-09-18 EA EA200000377A patent/EA002177B1/ru not_active IP Right Cessation
- 1998-09-18 UA UA2000041867A patent/UA66807C2/uk unknown
- 1998-09-18 US US09/509,652 patent/US6255346B1/en not_active Expired - Fee Related
- 1998-09-18 PL PL98339621A patent/PL189663B1/pl not_active IP Right Cessation
- 1998-09-18 PT PT98946703T patent/PT1022960E/pt unknown
- 1998-09-18 BR BR9812604-0A patent/BR9812604A/pt not_active Application Discontinuation
- 1998-09-18 EP EP98946703A patent/EP1022960B1/en not_active Expired - Lifetime
- 1998-09-18 AT AT98946703T patent/ATE220860T1/de not_active IP Right Cessation
-
2000
- 2000-03-24 IS IS5416A patent/IS2234B/is unknown
- 2000-03-30 BG BG104286A patent/BG64363B1/bg unknown
- 2000-03-31 NO NO20001688A patent/NO20001688L/no not_active Application Discontinuation
- 2000-10-26 HK HK00106847A patent/HK1028714A1/xx not_active IP Right Cessation
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
0001 | Granted |