IT1272290B - Sale della l-carnitina e composizioni farmaceutiche che lo contengono per il trattamento di affezioni cutanee - Google Patents
Sale della l-carnitina e composizioni farmaceutiche che lo contengono per il trattamento di affezioni cutaneeInfo
- Publication number
- IT1272290B IT1272290B ITRM940396A ITRM940396A IT1272290B IT 1272290 B IT1272290 B IT 1272290B IT RM940396 A ITRM940396 A IT RM940396A IT RM940396 A ITRM940396 A IT RM940396A IT 1272290 B IT1272290 B IT 1272290B
- Authority
- IT
- Italy
- Prior art keywords
- carnitine
- treatment
- pharmaceutical compositions
- salt
- contain
- Prior art date
Links
- PHIQHXFUZVPYII-ZCFIWIBFSA-N (R)-carnitine Chemical compound C[N+](C)(C)C[C@H](O)CC([O-])=O PHIQHXFUZVPYII-ZCFIWIBFSA-N 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 150000003839 salts Chemical class 0.000 title 1
- 208000017520 skin disease Diseases 0.000 title 1
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 abstract 2
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 abstract 1
- 230000000699 topical effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/365—Hydroxycarboxylic acids; Ketocarboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/006—Antidandruff preparations
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/22—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by oxygen atoms
Abstract
Viene descritta la L - carnitina glicolato e il suo uso per produrre composizioni farmaceutiche atte all'applicazione topica per il trattamento di affezioni cutanee.
Priority Applications (18)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITRM940396A IT1272290B (it) | 1994-06-20 | 1994-06-20 | Sale della l-carnitina e composizioni farmaceutiche che lo contengono per il trattamento di affezioni cutanee |
EP95830209A EP0688761A2 (en) | 1994-06-20 | 1995-05-18 | L-carnitine salt and cosmetic and pharmaceutical compositions containing same for treating dermatoses |
CA002150407A CA2150407A1 (en) | 1994-06-20 | 1995-05-29 | L-carnitine salt and cosmetic and pharmaceutical compositions containing same for treating dermatoses |
KR1019950014607A KR960000855A (ko) | 1994-06-20 | 1995-06-02 | L-카르니틴염과 이를 함유한 피부질환 치료용 화장품 조성물 및 약제조성물 |
US08/473,208 US5591450A (en) | 1994-06-20 | 1995-06-07 | L-carnitine salt and compositions containing same |
DE69502147T DE69502147T2 (de) | 1994-06-20 | 1995-06-12 | L-Carnitin Salz und dieses enthaltende Zusammensetzungen |
ES95109027T ES2116651T3 (es) | 1994-06-20 | 1995-06-12 | Sal de l-carnitina y composiciones que la contienen. |
AT95109027T ATE165338T1 (de) | 1994-06-20 | 1995-06-12 | L-carnitin salz und dieses enthaltende zusammensetzungen |
EP95109027A EP0697397B1 (en) | 1994-06-20 | 1995-06-12 | L-carnitine salt and compositions containing same |
PH50702A PH31606A (en) | 1994-06-20 | 1995-06-13 | L-carnitine salt and compositions containing them. |
KR1019950015962A KR960000217A (ko) | 1994-06-20 | 1995-06-16 | L- 카르니틴염과 이를 함유한 조성물 |
CA002152005A CA2152005A1 (en) | 1994-06-20 | 1995-06-16 | L-carnitine salt and compositions containing same |
ZA955024A ZA955024B (en) | 1994-06-20 | 1995-06-19 | L-carnitine salt and compositions containing same |
JP7151457A JPH0827081A (ja) | 1994-06-20 | 1995-06-19 | L−カルニチン塩および化粧用および皮膚病処置用医薬組成物 |
ZA955025A ZA955025B (en) | 1994-06-20 | 1995-06-19 | L-carnitine salt and cosmetic and pharmaceutical compositions containing same for treating dermatose |
JP7153148A JPH0826984A (ja) | 1994-06-20 | 1995-06-20 | L−カルニチン塩を含む組成物 |
TW084106325A TW300881B (it) | 1994-06-20 | 1995-06-20 | |
HK98104024A HK1004918A1 (en) | 1994-06-20 | 1998-05-09 | L-carnitine salt and compositions containing same |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITRM940396A IT1272290B (it) | 1994-06-20 | 1994-06-20 | Sale della l-carnitina e composizioni farmaceutiche che lo contengono per il trattamento di affezioni cutanee |
Publications (3)
Publication Number | Publication Date |
---|---|
ITRM940396A0 ITRM940396A0 (it) | 1994-06-20 |
ITRM940396A1 ITRM940396A1 (it) | 1995-12-20 |
IT1272290B true IT1272290B (it) | 1997-06-16 |
Family
ID=11402602
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ITRM940396A IT1272290B (it) | 1994-06-20 | 1994-06-20 | Sale della l-carnitina e composizioni farmaceutiche che lo contengono per il trattamento di affezioni cutanee |
Country Status (13)
Country | Link |
---|---|
US (1) | US5591450A (it) |
EP (2) | EP0688761A2 (it) |
JP (2) | JPH0827081A (it) |
KR (2) | KR960000855A (it) |
AT (1) | ATE165338T1 (it) |
CA (2) | CA2150407A1 (it) |
DE (1) | DE69502147T2 (it) |
ES (1) | ES2116651T3 (it) |
HK (1) | HK1004918A1 (it) |
IT (1) | IT1272290B (it) |
PH (1) | PH31606A (it) |
TW (1) | TW300881B (it) |
ZA (2) | ZA955025B (it) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1272290B (it) * | 1994-06-20 | 1997-06-16 | Avantgarde Spa | Sale della l-carnitina e composizioni farmaceutiche che lo contengono per il trattamento di affezioni cutanee |
AUPN115095A0 (en) * | 1995-02-15 | 1995-03-09 | Butt, Henry Lawrence | Analysis of and compositions and methods for the treatment of disease |
IT1276253B1 (it) | 1995-12-15 | 1997-10-27 | Sigma Tau Ind Farmaceuti | Composizione farmaceutica contenente l-carnitina o alcanoil l-carnitine per la prevenzione ed il trattamento di stati morbosi |
IT1289974B1 (it) * | 1997-02-25 | 1998-10-19 | Aldo Fassi | Procedimento per la produzione di sali stabili e non igroscopici di l(-)carnitina e di alcanoli l(-)-carnitine |
IT1291113B1 (it) * | 1997-03-20 | 1998-12-29 | Sigma Tau Ind Farmaceuti | Composizione nutritiva terapeutica per soggetti affetti da diabete mellito |
US6080788A (en) * | 1997-03-27 | 2000-06-27 | Sole; Michael J. | Composition for improvement of cellular nutrition and mitochondrial energetics |
US5863940A (en) | 1997-12-01 | 1999-01-26 | Sigma-Tau Healthscience S.P.A. | Medicament and therapeutical method for treating idiopathic asthenozoospermia |
US6090848A (en) * | 1997-12-01 | 2000-07-18 | Sigma-Tau Healthscience S.P.A. | Compositions and methods for increasing the concentration and/or motility of spermatozoa in humans |
DK0951909T4 (da) | 1998-03-19 | 2011-01-24 | Sigma Tau Ind Farmaceuti | Kombinationspræparat omfattende en L-carnitin eller en alkanoyl-L-carnitin, en glycosaminoglycan og/eller bestanddel deraf |
KR20000050756A (ko) * | 1999-01-14 | 2000-08-05 | 연규 | 핀 귀걸이의 제조방법과 그 제품의 구조 |
US6090849A (en) * | 1999-03-23 | 2000-07-18 | The Board Of Regents For Oklahoma State University | Carnitine supplemented diet to prevent sudden death syndrome in breeder type poultry |
ITRM20010364A1 (it) * | 2001-06-25 | 2002-12-27 | Biosalts Srl | Ascorbil derivati di carnitine e composizioni cosmetiche contenenti tali derivati. |
MXPA05010417A (es) * | 2003-03-28 | 2005-11-04 | Lonza Ag | Composiciones topicas de l-carnitina. |
JP4539096B2 (ja) * | 2004-01-16 | 2010-09-08 | 日油株式会社 | 油性成分被覆l−カルニチン塩粉末およびその用途 |
CN1322860C (zh) * | 2004-08-31 | 2007-06-27 | 北京正大绿洲医药科技有限公司 | 左旋肉碱滴丸及其制备方法 |
US7572832B2 (en) * | 2007-03-19 | 2009-08-11 | Biolink Life Sciences, Inc. | Non-hygroscopic L-carnitine salts |
KR101633846B1 (ko) | 2013-11-25 | 2016-06-27 | 주식회사 엘지화학 | 도전성 패턴 형성용 조성물 및 도전성 패턴을 갖는 수지 구조체 |
BR112017018580A2 (pt) * | 2015-03-27 | 2018-04-24 | Jiangsu Hengrui Medicine Co., Ltd. | p-toluenossulfonato para inibidor de mek quinase, e forma cristalina do mesmo e método de preparação para tal |
CN107216340B (zh) * | 2016-03-22 | 2021-05-04 | 中国科学院上海药物研究所 | 一种dppiv抑制剂的盐型及其制备方法 |
CN107216339B (zh) * | 2016-03-22 | 2021-05-04 | 中国科学院上海药物研究所 | 一种dppiv抑制剂马来酸盐的多晶型及其制备方法 |
SE542106C2 (en) * | 2016-08-26 | 2020-02-25 | Atif M Dabdoub | Dietary macro/micronutritional supplement for patients undergoing kidney dialysis |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3463261D1 (en) | 1983-12-28 | 1987-05-27 | Sigma Tau Ind Farmaceuti | Salts of l-carnitine and alkanoyl l-carnitines and process for preparing same |
FR2627385B3 (fr) * | 1988-02-23 | 1991-08-23 | Serobiologiques Lab Sa | Composition notamment utile comme matiere de base pour la preparation de compositions pharmaceutiques, notamment dermatologiques et/ou cosmetiques |
US4968719A (en) * | 1989-04-03 | 1990-11-06 | Sigma Tau, Industrie Farmaceutiche Riunite Spa | Method for treating vascular disease |
US5137910A (en) * | 1989-05-05 | 1992-08-11 | C.D. Searle & Co. | Compositions containing indole-2-carboxylate compounds for treatment of CNS disorders |
IT1263013B (it) * | 1992-10-20 | 1996-07-23 | Avantgarde Spa | Esteri della l-carnitina e di alcanoil l-carnitine con l'acido glicolico o suoi esteri e composizioni farmaceutiche contenenti tali per il trattamento di affezioni cutanee. |
IT1261984B (it) * | 1993-06-22 | 1996-06-11 | Avantgarde Spa | Uso di esteri della l-carnitina o di acil l- carnitine con idrossiacidi per produrre composizioni farmaceutiche per il trattamento di affezioni cutanee. |
IT1272290B (it) * | 1994-06-20 | 1997-06-16 | Avantgarde Spa | Sale della l-carnitina e composizioni farmaceutiche che lo contengono per il trattamento di affezioni cutanee |
-
1994
- 1994-06-20 IT ITRM940396A patent/IT1272290B/it active IP Right Grant
-
1995
- 1995-05-18 EP EP95830209A patent/EP0688761A2/en not_active Withdrawn
- 1995-05-29 CA CA002150407A patent/CA2150407A1/en not_active Abandoned
- 1995-06-02 KR KR1019950014607A patent/KR960000855A/ko not_active Application Discontinuation
- 1995-06-07 US US08/473,208 patent/US5591450A/en not_active Expired - Fee Related
- 1995-06-12 DE DE69502147T patent/DE69502147T2/de not_active Expired - Fee Related
- 1995-06-12 ES ES95109027T patent/ES2116651T3/es not_active Expired - Lifetime
- 1995-06-12 EP EP95109027A patent/EP0697397B1/en not_active Expired - Lifetime
- 1995-06-12 AT AT95109027T patent/ATE165338T1/de not_active IP Right Cessation
- 1995-06-13 PH PH50702A patent/PH31606A/en unknown
- 1995-06-16 KR KR1019950015962A patent/KR960000217A/ko not_active Application Discontinuation
- 1995-06-16 CA CA002152005A patent/CA2152005A1/en not_active Abandoned
- 1995-06-19 ZA ZA955025A patent/ZA955025B/xx unknown
- 1995-06-19 JP JP7151457A patent/JPH0827081A/ja active Pending
- 1995-06-19 ZA ZA955024A patent/ZA955024B/xx unknown
- 1995-06-20 JP JP7153148A patent/JPH0826984A/ja active Pending
- 1995-06-20 TW TW084106325A patent/TW300881B/zh active
-
1998
- 1998-05-09 HK HK98104024A patent/HK1004918A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
ZA955025B (en) | 1996-02-08 |
CA2152005A1 (en) | 1995-12-21 |
US5591450A (en) | 1997-01-07 |
EP0697397A1 (en) | 1996-02-21 |
DE69502147T2 (de) | 1998-08-13 |
ATE165338T1 (de) | 1998-05-15 |
HK1004918A1 (en) | 1998-12-11 |
EP0688761A3 (it) | 1996-01-17 |
TW300881B (it) | 1997-03-21 |
PH31606A (en) | 1998-11-03 |
EP0688761A2 (en) | 1995-12-27 |
DE69502147D1 (de) | 1998-05-28 |
EP0697397B1 (en) | 1998-04-22 |
CA2150407A1 (en) | 1995-12-21 |
ZA955024B (en) | 1996-02-08 |
JPH0827081A (ja) | 1996-01-30 |
ES2116651T3 (es) | 1998-07-16 |
KR960000855A (ko) | 1996-01-25 |
JPH0826984A (ja) | 1996-01-30 |
KR960000217A (ko) | 1996-01-25 |
ITRM940396A1 (it) | 1995-12-20 |
ITRM940396A0 (it) | 1994-06-20 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
0001 | Granted | ||
TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19970517 |