DE69734205D1 - Reinigung von kohlenhydraten mittels umkehrosmose und nanofiltration - Google Patents

Reinigung von kohlenhydraten mittels umkehrosmose und nanofiltration

Info

Publication number
DE69734205D1
DE69734205D1 DE69734205T DE69734205T DE69734205D1 DE 69734205 D1 DE69734205 D1 DE 69734205D1 DE 69734205 T DE69734205 T DE 69734205T DE 69734205 T DE69734205 T DE 69734205T DE 69734205 D1 DE69734205 D1 DE 69734205D1
Authority
DE
Germany
Prior art keywords
carbohydrates
nanofiltration
reverse osmosis
cleaning
oligosaccharides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69734205T
Other languages
English (en)
Other versions
DE69734205T2 (de
Inventor
Shawn Defrees
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Neose Technologies Inc
Original Assignee
Neose Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neose Technologies Inc filed Critical Neose Technologies Inc
Publication of DE69734205D1 publication Critical patent/DE69734205D1/de
Application granted granted Critical
Publication of DE69734205T2 publication Critical patent/DE69734205T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B30/00Preparation of starch, degraded or non-chemically modified starch, amylose, or amylopectin
    • CCHEMISTRY; METALLURGY
    • C13SUGAR INDUSTRY
    • C13BPRODUCTION OF SUCROSE; APPARATUS SPECIALLY ADAPTED THEREFOR
    • C13B20/00Purification of sugar juices
    • C13B20/16Purification of sugar juices by physical means, e.g. osmosis or filtration
    • C13B20/165Purification of sugar juices by physical means, e.g. osmosis or filtration using membranes, e.g. osmosis, ultrafiltration
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D61/00Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/02Reverse osmosis; Hyperfiltration ; Nanofiltration
    • B01D61/025Reverse osmosis; Hyperfiltration
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D61/00Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/02Reverse osmosis; Hyperfiltration ; Nanofiltration
    • B01D61/027Nanofiltration
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D61/00Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/02Reverse osmosis; Hyperfiltration ; Nanofiltration
    • B01D61/029Multistep processes comprising different kinds of membrane processes selected from reverse osmosis, hyperfiltration or nanofiltration
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D61/00Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/02Reverse osmosis; Hyperfiltration ; Nanofiltration
    • B01D61/04Feed pretreatment
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0003General processes for their isolation or fractionation, e.g. purification or extraction from biomass
    • CCHEMISTRY; METALLURGY
    • C13SUGAR INDUSTRY
    • C13KSACCHARIDES OBTAINED FROM NATURAL SOURCES OR BY HYDROLYSIS OF NATURALLY OCCURRING DISACCHARIDES, OLIGOSACCHARIDES OR POLYSACCHARIDES
    • C13K13/00Sugars not otherwise provided for in this class
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D2311/00Details relating to membrane separation process operations and control
    • B01D2311/04Specific process operations in the feed stream; Feed pretreatment
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/582Recycling of unreacted starting or intermediate materials

Landscapes

  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Water Supply & Treatment (AREA)
  • Nanotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Materials Engineering (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Sustainable Development (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Saccharide Compounds (AREA)
  • External Artificial Organs (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE69734205T 1996-10-10 1997-10-09 Reinigung von kohlenhydraten mittels umkehrosmose und nanofiltration Expired - Fee Related DE69734205T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US2822696P 1996-10-10 1996-10-10
US28226P 1996-10-10
PCT/US1997/018801 WO1998015581A1 (en) 1996-10-10 1997-10-09 Carbohydrate purification using ultrafiltration, reverse osmosis and nanofiltration

Publications (2)

Publication Number Publication Date
DE69734205D1 true DE69734205D1 (de) 2005-10-20
DE69734205T2 DE69734205T2 (de) 2006-07-06

Family

ID=21842245

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69734205T Expired - Fee Related DE69734205T2 (de) 1996-10-10 1997-10-09 Reinigung von kohlenhydraten mittels umkehrosmose und nanofiltration

Country Status (13)

Country Link
US (4) US6454946B1 (de)
EP (1) EP0931097B1 (de)
JP (1) JP2001502005A (de)
KR (1) KR100490507B1 (de)
AT (1) ATE304546T1 (de)
AU (1) AU735695B2 (de)
CA (1) CA2268168C (de)
DE (1) DE69734205T2 (de)
DK (1) DK0931097T3 (de)
HU (1) HUP0001634A2 (de)
IL (2) IL129363A (de)
NZ (1) NZ335203A (de)
WO (1) WO1998015581A1 (de)

Families Citing this family (87)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001502005A (ja) * 1996-10-10 2001-02-13 サイテル コーポレイション 限外濾過、逆浸透及びナノ濾過を利用する炭水化物の精製
EP1903114A3 (de) 1997-12-01 2008-07-23 Neose Technologies, Inc. Enzymatische Synthese von Gangliosiden
CN1086391C (zh) * 1998-12-12 2002-06-19 中国科学院新疆化学研究所 低聚糖纯化方法
US6942754B2 (en) 1999-03-23 2005-09-13 Oji Paper Co., Ltd. Process for producing xylooligosaccharide from lignocellulose pulp
US6824646B2 (en) 1999-03-23 2004-11-30 Oji Paper Co., Ltd. Process for oxygen bleaching and enzyme treating lignocellulosic pulp with liquid treatment and recovery
CA2627846C (en) * 1999-03-23 2011-01-04 Oji Paper Co., Ltd. Process for bleaching lignocellulose pulp
EP1276550A1 (de) * 2000-04-14 2003-01-22 Bryan Richard Tudhope Vorrichtung und verfahren zur isolierung und/oder beseitigung von gelösten stoffen aus einer lösung
US7465398B1 (en) 2000-09-29 2008-12-16 Delta-T Corporation Method for filtering and recovering solids from potato process water
AU2002219304A1 (en) * 2000-12-13 2002-06-24 Institut D'optique Theorique Et Appliquee Method for characterising a surface, and device therefor
US6736903B2 (en) * 2001-04-23 2004-05-18 Sunshine Raisin Corporation Method and apparatus for producing a work product
KR20020085699A (ko) * 2001-05-09 2002-11-16 박영규 단백질의 회전식 평판형 막분리방법 및 장치
IL161251A0 (en) 2001-10-10 2004-09-27 Neose Technologies Inc Remodeling and glycoconjugation of peptides
US7173003B2 (en) 2001-10-10 2007-02-06 Neose Technologies, Inc. Granulocyte colony stimulating factor: remodeling and glycoconjugation of G-CSF
US8008252B2 (en) 2001-10-10 2011-08-30 Novo Nordisk A/S Factor VII: remodeling and glycoconjugation of Factor VII
US7157277B2 (en) 2001-11-28 2007-01-02 Neose Technologies, Inc. Factor VIII remodeling and glycoconjugation of Factor VIII
US7214660B2 (en) * 2001-10-10 2007-05-08 Neose Technologies, Inc. Erythropoietin: remodeling and glycoconjugation of erythropoietin
US7795210B2 (en) 2001-10-10 2010-09-14 Novo Nordisk A/S Protein remodeling methods and proteins/peptides produced by the methods
DK2279753T3 (en) 2001-10-10 2015-11-23 Novo Nordisk As The conversion of peptides and glycokonjugering
US6648978B2 (en) * 2001-10-15 2003-11-18 A. E. Staley Manufacturing Co. Membrane filtration for thickening and starch washing in corn wet milling
MXPA04012496A (es) 2002-06-21 2005-09-12 Novo Nordisk Healthcare Ag Glicoformos del factor vii pegilados.
GB0229423D0 (en) 2002-12-18 2003-01-22 Avecia Ltd Process
US7888331B2 (en) 2003-03-06 2011-02-15 Seneb Biosciences, Inc. Ganglioside compositions and methods of use
BRPI0408358A (pt) 2003-03-14 2006-03-21 Neose Technologies Inc polìmeros hidrossolúveis ramificados e seus conjugados
MXPA05010773A (es) 2003-04-09 2005-12-12 Neose Technologies Inc Metodos de glicopegilacion y proteinas/peptidos producidos por los metodos.
US8791070B2 (en) 2003-04-09 2014-07-29 Novo Nordisk A/S Glycopegylated factor IX
BRPI0410164A (pt) 2003-05-09 2006-05-16 Neose Technologies Inc composições e métodos para preparação de mutantes de glicosilação de hormÈnio do crescimento humano
WO2005012484A2 (en) 2003-07-25 2005-02-10 Neose Technologies, Inc. Antibody-toxin conjugates
JP2005147788A (ja) * 2003-11-13 2005-06-09 Inst Nuclear Energy Research Rocaec 逆浸透分離法を用いたほう酸純化及び再利用システム及び方法
US7842661B2 (en) 2003-11-24 2010-11-30 Novo Nordisk A/S Glycopegylated erythropoietin formulations
US8633157B2 (en) 2003-11-24 2014-01-21 Novo Nordisk A/S Glycopegylated erythropoietin
US8075780B2 (en) * 2003-11-24 2011-12-13 Millipore Corporation Purification and concentration of synthetic biological molecules
US20080305992A1 (en) 2003-11-24 2008-12-11 Neose Technologies, Inc. Glycopegylated erythropoietin
US7956032B2 (en) 2003-12-03 2011-06-07 Novo Nordisk A/S Glycopegylated granulocyte colony stimulating factor
US20060040856A1 (en) 2003-12-03 2006-02-23 Neose Technologies, Inc. Glycopegylated factor IX
US7404926B2 (en) * 2003-12-30 2008-07-29 Rhoades Frank G Water treatment system
CN101072789B (zh) 2004-01-08 2013-05-15 生物种属学股份公司 肽的o-连接的糖基化
FR2848877B1 (fr) * 2004-01-28 2012-04-20 Applexion Ste Nouvelle De Rech S Et D Applic Ind D Echangeurs D Ions Applexion Procede de purification par nanofiltration d'une solution aqueuse sucree contenant des anions et cations monovalents et polyvalents
EP2484759B1 (de) 2004-02-04 2014-06-25 ratiopharm GmbH Verfahren zur Neufaltung von Säuger-Glykosyltransferasen
US20050287515A1 (en) * 2004-06-24 2005-12-29 Reinhold Deppisch Removal of bacterial DNA from therapeutic fluid formulations
US20080300173A1 (en) 2004-07-13 2008-12-04 Defrees Shawn Branched Peg Remodeling and Glycosylation of Glucagon-Like Peptides-1 [Glp-1]
ITMI20041627A1 (it) * 2004-08-06 2004-11-06 Lachifarma S R L Lab Chimi Co Processo per il recupero di tirosolo idrossitirosolo e altri componenti fenolici da acque di vegetazione e metodo di ossidazione catalitica di tirosolo a idrossitirosolo
WO2006031811A2 (en) 2004-09-10 2006-03-23 Neose Technologies, Inc. Glycopegylated interferon alpha
JP5948627B2 (ja) 2004-10-29 2016-07-20 レイショファーム ゲーエムベーハー 線維芽細胞成長因子(fgf)のリモデリングと糖質ペグ化
EP1858543B1 (de) 2005-01-10 2013-11-27 BioGeneriX AG Glycopegylierten Granulocyten-Kolonie-stimulierender Faktor
EP2386571B1 (de) 2005-04-08 2016-06-01 ratiopharm GmbH Zusammensetzungen und Verfahren zur Herstellung von Glycosylierungsmutanten eines Proteaseresistenten menschlichen Wachstumshormons
EP1869184B1 (de) 2005-04-11 2011-09-28 National Research Council Of Canada Identifizierung einer beta-1,3-n-acetylgalactosaminyltransferase (cgte) aus campylobacter jejuni lio87
EP2975135A1 (de) 2005-05-25 2016-01-20 Novo Nordisk A/S Glykopegylierter Faktor IX
CA2618769C (en) 2005-08-11 2014-03-04 National Research Council Of Canada Orf11 from campylobacter jejuni is a sialate-o-acetyltransferase
US20070105755A1 (en) 2005-10-26 2007-05-10 Neose Technologies, Inc. One pot desialylation and glycopegylation of therapeutic peptides
FI120590B (fi) * 2005-10-28 2009-12-15 Danisco Sweeteners Oy Erotusmenetelmä
WO2007056191A2 (en) * 2005-11-03 2007-05-18 Neose Technologies, Inc. Nucleotide sugar purification using membranes
DK1951060T3 (da) * 2005-11-04 2018-01-29 Arla Foods Amba Koncentrat afledt af et mælkeprodukt beriget med naturligt forekommende sialyllactose og en fremgangsmåde til fremstilling deraf
US9187532B2 (en) 2006-07-21 2015-11-17 Novo Nordisk A/S Glycosylation of peptides via O-linked glycosylation sequences
JP2010505874A (ja) 2006-10-03 2010-02-25 ノヴォ ノルディスク アー/エス ポリペプチドコンジュゲートの精製方法
CN101600448B (zh) 2006-10-04 2015-11-25 诺和诺德公司 甘油连接的peg化的糖和糖肽
KR100888513B1 (ko) * 2006-12-15 2009-03-12 주식회사 진켐 신규 n―아세틸글루코사민―2―에피머라아제 및 이를이용한 cmp―n―아세틸뉴라민산의 제조방법
KR20150064246A (ko) 2007-04-03 2015-06-10 바이오제너릭스 게엠베하 글리코페길화 g―csf를 이용하는 치료 방법
CA2690611C (en) 2007-06-12 2015-12-08 Novo Nordisk A/S Improved process for the production of nucleotide sugars
US8207112B2 (en) 2007-08-29 2012-06-26 Biogenerix Ag Liquid formulation of G-CSF conjugate
DK176760B1 (da) 2007-10-03 2009-06-29 Arla Foods Amba Process for producing lactose-free milk
WO2009108806A1 (en) 2008-02-27 2009-09-03 Novo Nordisk A/S Conjugated factor viii molecules
US8147735B2 (en) * 2008-07-09 2012-04-03 Eltron Research & Development, Inc. Semipermeable polymers and method for producing same
RU2516792C2 (ru) * 2008-12-09 2014-05-20 Торэй Индастриз, Инк. Способ получения сахарного раствора
US20120035120A1 (en) 2009-03-25 2012-02-09 Seneb Biosciences, Inc. Glycolipids as treatment for disease
JP5641598B2 (ja) * 2009-09-29 2014-12-17 雪印メグミルク株式会社 シアリルラクトース素材の分離方法
DE102010053749B4 (de) * 2010-12-08 2015-02-19 Airbus Defence and Space GmbH Vorrichtung zum Identifizieren biotischer Partikel
SG11201400260TA (en) * 2011-09-01 2014-03-28 Chugai Pharmaceutical Co Ltd Method for preparing a composition comprising highly concentrated antibodies by ultrafiltration
EP2596852A1 (de) * 2011-11-28 2013-05-29 Annikki GmbH Verfahren zur Aufarbeitung einer wässerigen, Lignin-enthaltenden Lösung mittels Nanofiltration
CN102532208B (zh) * 2012-01-06 2014-10-29 南京工业大学 一种连续分离唾液酸的方法
ITMI20121184A1 (it) * 2012-07-05 2014-01-06 Altergon Italia Srl Processo per la produzione industriale di ialuronato di sodio (hana) altamente purificato a peso molecolare controllato
EP2857410A1 (de) 2013-10-04 2015-04-08 Jennewein Biotechnologie GmbH Verfahren zur Reinigung von 2´-Fucosyllactose unter Verwendung simulierter Wanderbettchromatografie
PL2896628T3 (pl) 2014-01-20 2019-03-29 Jennewein Biotechnologie Gmbh Sposób wydajnego oczyszczania obojętnych oligosacharydów ludzkiego mleka (HMO) z fermentacji mikrobiologicznej
MX2017000773A (es) 2014-07-18 2017-04-27 Roquette Freres Metodo para extraer proteinas solubles de biomasa de microalgas.
GB201414213D0 (en) * 2014-08-11 2014-09-24 Imp Innovations Ltd Filtration process
MY186792A (en) 2016-02-04 2021-08-20 Ind Tech Res Inst Method for separating hydrolysis product of biomass
DE202017007249U1 (de) 2016-03-07 2020-04-23 Glycom A/S Abtrennung von Oligosacchariden aus der Fermentationsbrühe
DE202017007248U1 (de) * 2016-04-19 2020-04-23 Glycom A/S Abtrennung von Oligosacchariden aus der Fermentationsbrühe
US11160298B1 (en) * 2016-05-20 2021-11-02 Thermolife International, Llc Methods of producing decolorized beet products and compositions produced therefrom
WO2018020473A1 (en) 2016-07-28 2018-02-01 Fonterra Co-Operative Group Limited Dairy product and process
US20180199594A1 (en) * 2017-01-17 2018-07-19 Ian Mackay Process for producing protein concentrate or isolate and cellulosic thermochemical feedstock from brewes spent grains
EP3645545A4 (de) * 2017-06-30 2021-05-05 Glycom A/S Reinigung von oligosacchariden
EP3450443A1 (de) * 2017-08-29 2019-03-06 Jennewein Biotechnologie GmbH Verfahren zur reinigung sialylierter oligosaccharide
WO2019209559A1 (en) 2018-04-23 2019-10-31 Danisco Us Inc Synthesis of glucan comprising beta-1,3 glycosidic linkages with phosphorylase enzymes
SG11202010729XA (en) 2018-05-07 2020-11-27 Jennewein Biotechnologie Gmbh A SIMPLE METHOD FOR THE PURIFICATION OF LACTO-N-NEOTETRAOSE (LNnT) FROM CARBOHYDRATES OBTAINED BY MICROBIAL FERMENTATION
MX2020012855A (es) 2018-06-01 2021-02-17 Jennewein Biotechnologie Gmbh Proceso sencillo para la purificacion de una sialilactosa.
EP3686210A1 (de) * 2019-01-24 2020-07-29 DuPont Nutrition Biosciences ApS Verfahren zur reinigung eines muttermilch-oligosaccharids und zugehörige zusammensetzungen
KR20230151745A (ko) 2022-04-26 2023-11-02 (주)에코샤인 연속 생산이 가능한 한외여과 분리정제 장비

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4230463A (en) 1977-09-13 1980-10-28 Monsanto Company Multicomponent membranes for gas separations
US4259183A (en) 1978-11-07 1981-03-31 Midwest Research Institute Reverse osmosis membrane
US4562021A (en) 1983-09-06 1985-12-31 Ceraver, S.A. Method of manufacturing a medium for microfiltration, for ultrafiltration, or for reverse osmosis
DE3623796A1 (de) 1986-07-15 1988-01-28 Dow Chemical Rheinwerk Gmbh Vorrichtung und adsorptionsverfahren zur selektiven entfernung von ionen aus fluessigkeiten
US4692354A (en) 1986-08-12 1987-09-08 Masashi Asaeda Method for preparing ceramic membrane for separation of condensed component
US4741823A (en) 1986-12-23 1988-05-03 Osmonics, Inc. Flow control manifold for cross-flow membrane system
US4839037A (en) 1987-03-09 1989-06-13 Osmonics, Inc. Tapered, spirally wound filter cartridge and method of making same
US4956458A (en) 1988-05-13 1990-09-11 Warner-Lambert Company Purification of polydextrose by reverse osmosis
JP2805490B2 (ja) 1989-02-07 1998-09-30 雪印乳業株式会社 細菌毒素中和剤
DK165769C (da) * 1989-09-22 1993-06-14 Danisco Fremgangsmaade til fremstilling af en blanding af sakkarider og anvendelse af blandingen ved fremstilling af et kaloriefattigt levnedsmiddel
JPH03133387A (ja) * 1989-10-19 1991-06-06 Nichiden Kagaku Kk マルトオリゴ糖の製造方法
JP2802654B2 (ja) * 1989-10-30 1998-09-24 雪印乳業株式会社 ホエーの脱塩時に生ずる陰イオン交換樹脂のアルカリ洗浄廃液からのオリゴ糖結合型シアル酸類の回収方法
CA2038485A1 (en) * 1990-03-23 1991-09-24 Donald K. Hadden Nanofiltration process for making dextrose
JPH04108395A (ja) * 1990-08-28 1992-04-09 Higeta Shoyu Kk ガラクトサミノオリゴ糖の製造方法
IL99245A0 (en) 1990-09-04 1992-07-15 Taiyo Kagaku Kk Method for production of sialic acid
AU635352B2 (en) * 1990-11-09 1993-03-18 Applied Membrane Systems Pty Ltd A method and apparatus for fractionation of sugar containing solution
US5164374A (en) 1990-12-17 1992-11-17 Monsanto Company Use of oligosaccharides for treatment of arthritis
US5352670A (en) 1991-06-10 1994-10-04 Alberta Research Council Methods for the enzymatic synthesis of alpha-sialylated oligosaccharide glycosides
EP0562100B1 (de) * 1991-10-15 1996-12-11 The Nutrasweet Company Zuckerabtrennung in säften
JPH05168490A (ja) * 1991-12-20 1993-07-02 Fushimi Seiyakushiyo:Kk 生理活性ペクチンオリゴマーの製造方法及び使用方法
JPH0686684A (ja) * 1992-05-26 1994-03-29 Monsanto Co シアロ抱合体の合成
EP1621554B2 (de) * 1992-08-21 2012-08-29 Vrije Universiteit Brussel Immunoglobuline ohne Leichtkette
US5374541A (en) 1993-05-04 1994-12-20 The Scripps Research Institute Combined use of β-galactosidase and sialyltransferase coupled with in situ regeneration of CMP-sialic acid for one pot synthesis of oligosaccharides
CN1129953A (zh) 1993-07-15 1996-08-28 尼奥斯药品公司 糖组分的合成方法
BE1007425A3 (nl) 1993-08-30 1995-06-13 Holland Sweetener Co Werkwijze en inrichting voor de terugwinning van grondstoffen in het aspartaambereidingsproces.
WO1995012160A2 (en) 1993-10-28 1995-05-04 Maisotsenko Valeriy S Method of determining working media motion and designing flow structures for same
AU3823195A (en) 1994-09-12 1996-03-29 Aeci Limited Process for recovering citric acid
US6030815A (en) * 1995-04-11 2000-02-29 Neose Technologies, Inc. Enzymatic synthesis of oligosaccharides
US5876980A (en) 1995-04-11 1999-03-02 Cytel Corporation Enzymatic synthesis of oligosaccharides
US5728554A (en) * 1995-04-11 1998-03-17 Cytel Corporation Enzymatic synthesis of glycosidic linkages
US5676980A (en) * 1995-09-29 1997-10-14 Continental General Tire, Inc. Center split segmented mold for curing pneumatic tires
JP2001502005A (ja) * 1996-10-10 2001-02-13 サイテル コーポレイション 限外濾過、逆浸透及びナノ濾過を利用する炭水化物の精製
US6288222B1 (en) * 2000-02-16 2001-09-11 Neose Technologies, Inc. Method of filtration of a dairy stream

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IL129363A (en) 2003-02-12
WO1998015581A1 (en) 1998-04-16
EP0931097A4 (de) 2000-01-12
EP0931097A1 (de) 1999-07-28
US20020148791A1 (en) 2002-10-17
US20050269265A1 (en) 2005-12-08
HUP0001634A2 (hu) 2000-09-28
JP2001502005A (ja) 2001-02-13
AU735695B2 (en) 2001-07-12
KR100490507B1 (ko) 2005-05-19
KR20000049057A (ko) 2000-07-25
ATE304546T1 (de) 2005-09-15
IL149275A (en) 2007-07-04
US6454946B1 (en) 2002-09-24
US20030029799A1 (en) 2003-02-13
NZ335203A (en) 2000-10-27
CA2268168A1 (en) 1998-04-16
IL129363A0 (en) 2000-02-17
EP0931097B1 (de) 2005-09-14
DE69734205T2 (de) 2006-07-06
CA2268168C (en) 2008-04-29
AU5081698A (en) 1998-05-05
DK0931097T3 (da) 2006-01-16
US6936173B2 (en) 2005-08-30

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