AU2001276629A1 - Modulation of tetraspanin function - Google Patents

Modulation of tetraspanin function

Info

Publication number
AU2001276629A1
AU2001276629A1 AU2001276629A AU7662901A AU2001276629A1 AU 2001276629 A1 AU2001276629 A1 AU 2001276629A1 AU 2001276629 A AU2001276629 A AU 2001276629A AU 7662901 A AU7662901 A AU 7662901A AU 2001276629 A1 AU2001276629 A1 AU 2001276629A1
Authority
AU
Australia
Prior art keywords
tetraspanin
modulation
function
tetraspanins
dimerise
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001276629A
Inventor
Martino Bolognesi
Guido Grandi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GSK Vaccines SRL
Original Assignee
Chiron SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiron SRL filed Critical Chiron SRL
Publication of AU2001276629A1 publication Critical patent/AU2001276629A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70596—Molecules with a "CD"-designation not provided for elsewhere
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2299/00—Coordinates from 3D structures of peptides, e.g. proteins or enzymes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

Tetraspanins have been found to dimerise. Methods for inhibiting or promoting the dimerisation of tetraspanins are provided, which may involve protein engineering of the tetraspanins themselves, or may rely on other molecules.
AU2001276629A 2000-07-03 2001-07-03 Modulation of tetraspanin function Abandoned AU2001276629A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0016362 2000-07-03
GBGB0016362.6A GB0016362D0 (en) 2000-07-03 2000-07-03 Tetraspanin modulation
PCT/IB2001/001458 WO2002002632A2 (en) 2000-07-03 2001-07-03 Modulation of tetraspanin function

Publications (1)

Publication Number Publication Date
AU2001276629A1 true AU2001276629A1 (en) 2002-01-14

Family

ID=9894962

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001276629A Abandoned AU2001276629A1 (en) 2000-07-03 2001-07-03 Modulation of tetraspanin function

Country Status (7)

Country Link
US (1) US7252958B2 (en)
EP (1) EP1301536B1 (en)
AT (1) ATE328904T1 (en)
AU (1) AU2001276629A1 (en)
DE (1) DE60120410T2 (en)
GB (1) GB0016362D0 (en)
WO (1) WO2002002632A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007038762A2 (en) * 2005-09-28 2007-04-05 University Of Utah Research Foundation Penumbra nucleic acid molecules, proteins and uses thereof
US8372810B2 (en) 2007-04-11 2013-02-12 Gene Signal International Sa Anti-tumor drug, medicament, composition, and use thereof
ES2385115T3 (en) * 2007-04-11 2012-07-18 Gene Signal International Sa Drug, medication, antitumor composition and its use
CN105111283B (en) * 2015-08-21 2018-08-24 天津医科大学 A kind of small peptide and the composition formed is connected by the small peptide
SG11202100864VA (en) * 2018-08-14 2021-02-25 Evercyte Gmbh Target-specific extracellular vesicles

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2373616A1 (en) 1999-05-19 2000-11-23 Human Genome Sciences, Inc. Tm4sf receptors

Also Published As

Publication number Publication date
US20040023297A1 (en) 2004-02-05
DE60120410T2 (en) 2007-01-04
DE60120410D1 (en) 2006-07-20
WO2002002632A3 (en) 2002-05-10
EP1301536B1 (en) 2006-06-07
US7252958B2 (en) 2007-08-07
EP1301536A2 (en) 2003-04-16
GB0016362D0 (en) 2000-08-23
ATE328904T1 (en) 2006-06-15
WO2002002632A2 (en) 2002-01-10

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