WO1999028465A3 - Pias molecules that recognize and bind stat proteins and uses thereof - Google Patents
Pias molecules that recognize and bind stat proteins and uses thereof Download PDFInfo
- Publication number
- WO1999028465A3 WO1999028465A3 PCT/US1998/025316 US9825316W WO9928465A3 WO 1999028465 A3 WO1999028465 A3 WO 1999028465A3 US 9825316 W US9825316 W US 9825316W WO 9928465 A3 WO9928465 A3 WO 9928465A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- pias
- molecules
- recognize
- stat proteins
- bind
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
- C07K14/4703—Inhibitors; Suppressors
Abstract
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/573,651 US7265202B1 (en) | 1997-11-28 | 1998-11-27 | PIAS molecules that recognize and bind STAT proteins and uses thereof |
AU16106/99A AU1610699A (en) | 1997-11-28 | 1998-11-27 | Pias molecules that recognize and bind stat proteins and uses thereof |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US6925197P | 1997-11-28 | 1997-11-28 | |
US60/069,251 | 1997-11-28 | ||
US9595098P | 1998-08-10 | 1998-08-10 | |
US60/095,950 | 1998-08-10 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO1999028465A2 WO1999028465A2 (en) | 1999-06-10 |
WO1999028465A3 true WO1999028465A3 (en) | 1999-10-07 |
Family
ID=26749861
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1998/025316 WO1999028465A2 (en) | 1997-11-28 | 1998-11-27 | Pias molecules that recognize and bind stat proteins and uses thereof |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO1999028465A2 (en) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2736400A (en) | 1999-01-27 | 2000-08-18 | University Of South Florida | Inhibition of stat3 signal transduction for human cancer therapy |
WO2002072612A2 (en) * | 2001-03-12 | 2002-09-19 | Praecis Pharmaceuticals Incorporated | Peptidic modulators of the androgen receptor |
AU2003215622A1 (en) * | 2002-02-28 | 2003-09-09 | Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw | Use of plag1 and plagl2 in cancer diagnosis and drug screening |
US7638122B2 (en) | 2003-03-07 | 2009-12-29 | University Of South Florida | Stat3 antagonists and their use as vaccines against cancer |
WO2011110359A1 (en) * | 2010-03-10 | 2011-09-15 | Georg-Speyer-Haus Chemotherapeutisches Forschungsinstitut | Stat3 activation inhibitors |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1995031544A1 (en) * | 1994-05-11 | 1995-11-23 | Yeda Research And Development Co., Ltd. | Modulator of tnf/ngf superfamily receptors and soluble oligomeric tnf/ngf superfamily receptors |
WO1996020954A2 (en) * | 1995-01-06 | 1996-07-11 | The Rockefeller University | Functionally active domains of signal transducer and activators of transcription (stat) proteins |
-
1998
- 1998-11-27 WO PCT/US1998/025316 patent/WO1999028465A2/en active Application Filing
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1995031544A1 (en) * | 1994-05-11 | 1995-11-23 | Yeda Research And Development Co., Ltd. | Modulator of tnf/ngf superfamily receptors and soluble oligomeric tnf/ngf superfamily receptors |
WO1996020954A2 (en) * | 1995-01-06 | 1996-07-11 | The Rockefeller University | Functionally active domains of signal transducer and activators of transcription (stat) proteins |
Non-Patent Citations (6)
Title |
---|
CHUNG C D ET AL: "SPECIFIC INHIBITION OF STAT3 SIGNAL TRANSDUCTION BY PIAS3", SCIENCE, vol. 278, 5 December 1997 (1997-12-05), pages 1803 - 1805, XP002072146, ISSN: 0036-8075 * |
IVASHKIV, L.B. ET AL.: "Inhibition of transcription factor STAT1 activity in mononuclear cell cultures and T cells by the cyclic AMP signaling pathway.", JOURNAL OF IMMUNOLOGY, vol. 157, 1996, pages 1415 - 21, XP002109567 * |
LIU, B. ET AL.: "Inhibition of Stat1-mediated gene activation by PIAS1.", PROC.NAT'L.ACAD.SCI.USA, vol. 95, September 1998 (1998-09-01), pages 10626 - 31, XP002109569 * |
MINAMOTO, S. ET AL.: "Cloning and functional analysis of new members of STAT induced STAT inhibitors (SSI) family: SSI-2 and SSI-3.", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, vol. 237, no. 1, July 1997 (1997-07-01), pages 79 - 83, XP002109568 * |
VALDEZ, B.C. ET AL.: "Cloning and characterization of Gu/RH-II binding protein.", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, vol. 234, no. 2, 19 May 1997 (1997-05-19), pages 335 - 40, XP002109565 * |
WU, L. ET AL.: "Miz1, a novel zinc finger transcription factor that interacts with Msx2 and enhances its affinity for DNA", MECHANISMS OF DEVELOPMENT, vol. 65, no. 1-2, July 1997 (1997-07-01), pages 3 - 17, XP002109566 * |
Also Published As
Publication number | Publication date |
---|---|
WO1999028465A2 (en) | 1999-06-10 |
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