MXPA05009480A - Metodos y composiciones para la sintesis enzimatica de gangliosidos. - Google Patents

Metodos y composiciones para la sintesis enzimatica de gangliosidos.

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Publication number
MXPA05009480A
MXPA05009480A MXPA05009480A MXPA05009480A MXPA05009480A MX PA05009480 A MXPA05009480 A MX PA05009480A MX PA05009480 A MXPA05009480 A MX PA05009480A MX PA05009480 A MXPA05009480 A MX PA05009480A MX PA05009480 A MXPA05009480 A MX PA05009480A
Authority
MX
Mexico
Prior art keywords
methods
compositions
gangliosides
enzymatic synthesis
glycosphingolipids
Prior art date
Application number
MXPA05009480A
Other languages
English (en)
Inventor
Zhi-Guang Wang
Original Assignee
Neose Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neose Technologies Inc filed Critical Neose Technologies Inc
Publication of MXPA05009480A publication Critical patent/MXPA05009480A/es

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    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
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    • A61P25/00Drugs for disorders of the nervous system
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    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
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    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02Acyclic radicals, not substituted by cyclic structures
    • C07H15/04Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C07H15/10Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical containing unsaturated carbon-to-carbon bonds
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    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/26Acyclic or carbocyclic radicals, substituted by hetero rings

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
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  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Neurology (AREA)
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  • Biochemistry (AREA)
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  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Diabetes (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
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  • Psychiatry (AREA)
  • Psychology (AREA)
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  • Physical Education & Sports Medicine (AREA)
  • Hematology (AREA)
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Abstract

Se describen nuevos glicosfingolipidos sinteticos y composiciones farmaceuticas que contienen tales glicosfingolipidos sinteticos. Tambien se describen metodos para fabricar los nuevos compuestos glicosfingolipidos sinteticos y composiciones, tambien como su uso en el campo de neuroproteccion y tratamiento de cancer.
MXPA05009480A 2003-03-06 2004-03-04 Metodos y composiciones para la sintesis enzimatica de gangliosidos. MXPA05009480A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US45279603P 2003-03-06 2003-03-06
PCT/US2004/006904 WO2004080960A2 (en) 2003-03-06 2004-03-04 Methods and compositions for the enzymatic synthesis of gangliosides

Publications (1)

Publication Number Publication Date
MXPA05009480A true MXPA05009480A (es) 2006-02-22

Family

ID=32990686

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA05009480A MXPA05009480A (es) 2003-03-06 2004-03-04 Metodos y composiciones para la sintesis enzimatica de gangliosidos.

Country Status (8)

Country Link
US (1) US7888331B2 (es)
EP (1) EP1603932B1 (es)
JP (1) JP2006519878A (es)
AU (1) AU2004220087A1 (es)
CA (1) CA2518171C (es)
MX (1) MXPA05009480A (es)
NZ (2) NZ567841A (es)
WO (1) WO2004080960A2 (es)

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US9023812B2 (en) 2009-09-04 2015-05-05 The Governors Of The University Of Alberta Neuroprotective ganglioside compositions for use in treating huntington's disease
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WO2013070677A1 (en) * 2011-11-07 2013-05-16 The Regents Of The University Of California PmST3 ENZYME FOR CHEMOENZYMATIC SYNTHESIS OF ALPHA-2-3-SIALOSIDES
US9102967B2 (en) 2012-01-11 2015-08-11 The Regents Of The University Of California PmST2 enzyme for chemoenzymatic synthesis of α-2-3-sialylglycolipids
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CA2518171A1 (en) 2004-09-23
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JP2006519878A (ja) 2006-08-31
WO2004080960A2 (en) 2004-09-23
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