IT1232175B - Analoghi semisintetici di gangliosidi - Google Patents

Analoghi semisintetici di gangliosidi

Info

Publication number
IT1232175B
IT1232175B IT8948246A IT4824689A IT1232175B IT 1232175 B IT1232175 B IT 1232175B IT 8948246 A IT8948246 A IT 8948246A IT 4824689 A IT4824689 A IT 4824689A IT 1232175 B IT1232175 B IT 1232175B
Authority
IT
Italy
Prior art keywords
acyl
dilysogangliosides
derived
gangliosides
carbon atoms
Prior art date
Application number
IT8948246A
Other languages
English (en)
Other versions
IT8948246A0 (it
Inventor
Francesco Della Valle
Aurelio Romeo
Original Assignee
Fidia Farmaceutici
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fidia Farmaceutici filed Critical Fidia Farmaceutici
Publication of IT8948246A0 publication Critical patent/IT8948246A0/it
Priority to IT8948246A priority Critical patent/IT1232175B/it
Priority to IL95169A priority patent/IL95169A0/xx
Priority to AT90402139T priority patent/ATE158297T1/de
Priority to AU59829/90A priority patent/AU5982990A/en
Priority to DE69031448T priority patent/DE69031448T2/de
Priority to EP90402139A priority patent/EP0410881B1/en
Priority to NZ234649A priority patent/NZ234649A/en
Priority to ES90402139T priority patent/ES2106025T3/es
Priority to HU904640A priority patent/HU210923B/hu
Priority to NO90903333A priority patent/NO903333L/no
Priority to CA002022138A priority patent/CA2022138A1/en
Priority to KR1019900011755A priority patent/KR910002887A/ko
Priority to JP2201059A priority patent/JPH0358995A/ja
Priority to FI903753A priority patent/FI903753A7/fi
Priority to PL90286249A priority patent/PL165209B1/pl
Application granted granted Critical
Publication of IT1232175B publication Critical patent/IT1232175B/it
Priority to US08/096,853 priority patent/US5484775A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C07H15/10—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical containing unsaturated carbon-to-carbon bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biotechnology (AREA)
  • Public Health (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Lead Frames For Integrated Circuits (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
IT8948246A 1989-07-07 1989-07-27 Analoghi semisintetici di gangliosidi IT1232175B (it)

Priority Applications (16)

Application Number Priority Date Filing Date Title
IT8948246A IT1232175B (it) 1989-07-27 1989-07-27 Analoghi semisintetici di gangliosidi
IL95169A IL95169A0 (en) 1989-07-27 1990-07-24 Semisynthetic ganglioside analogues
AT90402139T ATE158297T1 (de) 1989-07-27 1990-07-25 Halbsynthetische gangliosidanaloge
AU59829/90A AU5982990A (en) 1989-07-27 1990-07-25 Semisynthetic ganglioside analogues
DE69031448T DE69031448T2 (de) 1989-07-27 1990-07-25 Halbsynthetische Gangliosidanaloge
EP90402139A EP0410881B1 (en) 1989-07-27 1990-07-25 Semisynthetic ganglioside analogues
NZ234649A NZ234649A (en) 1989-07-27 1990-07-25 Semisynthetic ganglioside analogues and pharmaceutical compositions
ES90402139T ES2106025T3 (es) 1989-07-27 1990-07-25 Analogos de gangliosidos semisinteticos.
HU904640A HU210923B (en) 1989-07-27 1990-07-26 Process to prepare semisynthetic ganglioside analogues and pharmaceutical compns. conts. them as active agent
NO90903333A NO903333L (no) 1989-07-27 1990-07-26 Fremgangsmaate til fremstilling av semisyntetiske gangliosidanaloger.
CA002022138A CA2022138A1 (en) 1989-07-27 1990-07-27 Semisynthetic ganglioside analogues
KR1019900011755A KR910002887A (ko) 1989-07-07 1990-07-27 신규한 아실-리조강글리오사이드와 그의 제조방법
JP2201059A JPH0358995A (ja) 1989-07-27 1990-07-27 半合成ガングリオシド類似体
FI903753A FI903753A7 (fi) 1989-07-27 1990-07-27 Menetelmä terapeuttisesti käyttökelpoisten puolisynteettisten gangliosidijohdannaisten valmistamiseksi
PL90286249A PL165209B1 (pl) 1989-07-27 1990-07-27 S posób wytwarzania pólsyntetycznych pochodnych N,N-dilizogangliozydów GM 1 PL PL
US08/096,853 US5484775A (en) 1989-07-27 1993-07-26 Semisynthetic ganglioside analogues

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8948246A IT1232175B (it) 1989-07-27 1989-07-27 Analoghi semisintetici di gangliosidi

Publications (2)

Publication Number Publication Date
IT8948246A0 IT8948246A0 (it) 1989-07-27
IT1232175B true IT1232175B (it) 1992-01-25

Family

ID=11265466

Family Applications (1)

Application Number Title Priority Date Filing Date
IT8948246A IT1232175B (it) 1989-07-07 1989-07-27 Analoghi semisintetici di gangliosidi

Country Status (16)

Country Link
US (1) US5484775A (it)
EP (1) EP0410881B1 (it)
JP (1) JPH0358995A (it)
KR (1) KR910002887A (it)
AT (1) ATE158297T1 (it)
AU (1) AU5982990A (it)
CA (1) CA2022138A1 (it)
DE (1) DE69031448T2 (it)
ES (1) ES2106025T3 (it)
FI (1) FI903753A7 (it)
HU (1) HU210923B (it)
IL (1) IL95169A0 (it)
IT (1) IT1232175B (it)
NO (1) NO903333L (it)
NZ (1) NZ234649A (it)
PL (1) PL165209B1 (it)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1232176B (it) * 1989-07-27 1992-01-25 Fidia Farmaceutici Derivati di-lisogangliosidi
IT1239060B (it) * 1990-05-04 1993-09-20 Fidia Spa Processo per la modulazione selettiva dell'espressione e della funzione di un determinante sulla superficie cellulare attraverso appropriati agenti chimici
IT1253832B (it) * 1991-08-01 1995-08-29 Fidia Spa Derivati di gangliosidi
DE4204907A1 (de) * 1992-02-14 1993-08-19 Reutter Werner Neuartige glykokonjugate mit n-substituierten neuraminsaeuren als mittel zur stimulierung des immunsystems
AU2002326805B2 (en) 2001-08-29 2009-01-22 Seneb Biosciences, Inc. Novel synthetic ganglioside derivatives and compositions thereof
AU2004220087A1 (en) 2003-03-06 2004-09-23 Seneb Biosciences, Inc. Methods and compositions for the enzymatic synthesis of gangliosides
WO2010111530A1 (en) * 2009-03-25 2010-09-30 Seneb Biosciences, Inc. Glycolipids as treatment for disease
KR102706721B1 (ko) 2015-10-09 2024-09-12 텐사 코포레이션, 엘엘씨 공압출된 다층 폴리머로 제조된 지오그리드

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4593091A (en) * 1981-08-04 1986-06-03 Fidia, S.P.A. Method for preparing ganglioside derivatives and use thereof in pharmaceutical compositions
US4716223A (en) * 1981-08-04 1987-12-29 Fidia, S.P.A. Method for preparing ganglioside derivatives and use thereof in pharmaceutical compositions
US4476119A (en) * 1981-08-04 1984-10-09 Fidia S.P.A. Method for preparing ganglioside derivatives and use thereof in pharmaceutical compositions
IT1199116B (it) * 1984-07-03 1988-12-30 Fidia Farmaceutici Derivati di gangliosidi
JPH06795B2 (ja) * 1985-04-02 1994-01-05 理化学研究所 アシアロガングリオシド関連化合物の製造方法
ES2065343T3 (es) * 1987-06-26 1995-02-16 Solco Basel Ag Nuevos preparados farmaceuticos asi como nuevos compuestos de lactosilo y su preparacion.
IT1212041B (it) * 1987-11-02 1989-11-08 Fidia Farmaceutici Gangliosidi esteri interni come agenti terapeutici capaci di eliminare il dolore nelle neuropatie periferiche
CA1339488C (en) * 1988-02-12 1997-10-07 Taeko Dohi De-n-acetyl-syalic acid and their applications as modifiers of cell physiology
IT1235161B (it) * 1988-12-02 1992-06-22 Fidia Farmaceutici Derivati di lisogangliosidi
IT1253832B (it) * 1991-08-01 1995-08-29 Fidia Spa Derivati di gangliosidi

Also Published As

Publication number Publication date
JPH0358995A (ja) 1991-03-14
IL95169A0 (en) 1991-06-10
CA2022138A1 (en) 1991-01-28
HUT54173A (en) 1991-01-28
EP0410881A2 (en) 1991-01-30
HU210923B (en) 1995-09-28
US5484775A (en) 1996-01-16
NO903333D0 (no) 1990-07-26
AU5982990A (en) 1991-01-31
EP0410881B1 (en) 1997-09-17
EP0410881A3 (en) 1993-01-20
PL165209B1 (pl) 1994-11-30
FI903753A0 (fi) 1990-07-27
FI903753A7 (fi) 1991-01-28
HU904640D0 (en) 1991-01-28
KR910002887A (ko) 1991-02-26
IT8948246A0 (it) 1989-07-27
PL286249A1 (en) 1991-08-26
DE69031448T2 (de) 1998-02-26
ES2106025T3 (es) 1997-11-01
NZ234649A (en) 1992-01-29
DE69031448D1 (de) 1997-10-23
NO903333L (no) 1991-01-28
ATE158297T1 (de) 1997-10-15

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Legal Events

Date Code Title Description
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19960701