IT1235161B - Derivati di lisogangliosidi - Google Patents

Derivati di lisogangliosidi

Info

Publication number
IT1235161B
IT1235161B IT8848618A IT4861888A IT1235161B IT 1235161 B IT1235161 B IT 1235161B IT 8848618 A IT8848618 A IT 8848618A IT 4861888 A IT4861888 A IT 4861888A IT 1235161 B IT1235161 B IT 1235161B
Authority
IT
Italy
Prior art keywords
lysogangliosides
acyl
derivatives
group
deacyation
Prior art date
Application number
IT8848618A
Other languages
English (en)
Other versions
IT8848618A0 (it
Inventor
Della Valle Francesco
Romeo Aurelio
Original Assignee
Fidia Farmaceutici
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fidia Farmaceutici filed Critical Fidia Farmaceutici
Publication of IT8848618A0 publication Critical patent/IT8848618A0/it
Priority to IT8848618A priority Critical patent/IT1235161B/it
Priority to DK589889A priority patent/DK589889A/da
Priority to DE68914418T priority patent/DE68914418T2/de
Priority to EP89403310A priority patent/EP0373039B1/en
Priority to AT89403310T priority patent/ATE103926T1/de
Priority to CA002004189A priority patent/CA2004189A1/en
Priority to ES89403310T priority patent/ES2063156T3/es
Priority to IL92513A priority patent/IL92513A0/xx
Priority to HU896337A priority patent/HU205129B/hu
Priority to AU45718/89A priority patent/AU630384B2/en
Priority to NO894820A priority patent/NO173141C/no
Priority to FI895765A priority patent/FI95577C/fi
Priority to JP1314135A priority patent/JPH02200697A/ja
Priority to KR1019890017924A priority patent/KR910009721A/ko
Priority to NZ231624A priority patent/NZ231624A/en
Application granted granted Critical
Publication of IT1235161B publication Critical patent/IT1235161B/it
Priority to US08/268,730 priority patent/US6407072B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/12—Acyclic radicals, not substituted by cyclic structures attached to a nitrogen atom of the saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C07H15/10—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical containing unsaturated carbon-to-carbon bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Psychology (AREA)
  • Psychiatry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
IT8848618A 1988-12-02 1988-12-02 Derivati di lisogangliosidi IT1235161B (it)

Priority Applications (16)

Application Number Priority Date Filing Date Title
IT8848618A IT1235161B (it) 1988-12-02 1988-12-02 Derivati di lisogangliosidi
DK589889A DK589889A (da) 1988-12-02 1989-11-23 Lysogangliosid-derivater
DE68914418T DE68914418T2 (de) 1988-12-02 1989-11-29 Lysoganglioside-Derivate.
EP89403310A EP0373039B1 (en) 1988-12-02 1989-11-29 New lysoganglioside derivatives
AT89403310T ATE103926T1 (de) 1988-12-02 1989-11-29 Lysoganglioside-derivate.
CA002004189A CA2004189A1 (en) 1988-12-02 1989-11-29 Lysoganglioside derivitives
ES89403310T ES2063156T3 (es) 1988-12-02 1989-11-29 Nuevos derivados lisogangliosidos.
HU896337A HU205129B (en) 1988-12-02 1989-12-01 Process for producing lysoganglioside derivatives, as well as pharmaceutical compositions comprising such derivatives as active ingredient
IL92513A IL92513A0 (en) 1988-12-02 1989-12-01 Lysoganglioside derivatives
AU45718/89A AU630384B2 (en) 1988-12-02 1989-12-01 New lysoganglioside derivatives
NO894820A NO173141C (no) 1988-12-02 1989-12-01 Analogifremgangsmaate ved fremstilling av n-acyllysogangliosider
FI895765A FI95577C (fi) 1988-12-02 1989-12-01 Menetelmä uusien, terapeuttisesti käyttökelpoisten lysogangliosidijohdannaisten valmistamiseksi
JP1314135A JPH02200697A (ja) 1988-12-02 1989-12-02 リゾガングリオシド誘導体
KR1019890017924A KR910009721A (ko) 1988-12-02 1989-12-02 신규한 n-아실-리조강글리오시드와 그의 유도체 및 그의 제조방법
NZ231624A NZ231624A (en) 1988-12-02 1989-12-04 Ganglioside derivatives, medicaments
US08/268,730 US6407072B1 (en) 1988-12-02 1994-06-30 Lysoganglioside derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8848618A IT1235161B (it) 1988-12-02 1988-12-02 Derivati di lisogangliosidi

Publications (2)

Publication Number Publication Date
IT8848618A0 IT8848618A0 (it) 1988-12-02
IT1235161B true IT1235161B (it) 1992-06-22

Family

ID=11267667

Family Applications (1)

Application Number Title Priority Date Filing Date
IT8848618A IT1235161B (it) 1988-12-02 1988-12-02 Derivati di lisogangliosidi

Country Status (15)

Country Link
EP (1) EP0373039B1 (it)
JP (1) JPH02200697A (it)
KR (1) KR910009721A (it)
AT (1) ATE103926T1 (it)
AU (1) AU630384B2 (it)
CA (1) CA2004189A1 (it)
DE (1) DE68914418T2 (it)
DK (1) DK589889A (it)
ES (1) ES2063156T3 (it)
FI (1) FI95577C (it)
HU (1) HU205129B (it)
IL (1) IL92513A0 (it)
IT (1) IT1235161B (it)
NO (1) NO173141C (it)
NZ (1) NZ231624A (it)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1235011B (it) * 1988-07-26 1992-06-16 Fidia Farmaceutici Sintesi di derivati di glicosfingolipidi ed in particolare di gangliosidi utilizzabili per la preparazione di immunoadsorbenti ed adsorbenti per affinita' impiegabili per la purificazione di anticorpi e di tossine specifiche, e per uso diagnostico
IT1232175B (it) * 1989-07-27 1992-01-25 Fidia Farmaceutici Analoghi semisintetici di gangliosidi
IT1232176B (it) * 1989-07-27 1992-01-25 Fidia Farmaceutici Derivati di-lisogangliosidi
IT1238346B (it) * 1989-11-14 1993-07-13 Gangliosidi modificati e loro derivati funzionali.
IT1239060B (it) * 1990-05-04 1993-09-20 Fidia Spa Processo per la modulazione selettiva dell'espressione e della funzione di un determinante sulla superficie cellulare attraverso appropriati agenti chimici
IT1253832B (it) * 1991-08-01 1995-08-29 Fidia Spa Derivati di gangliosidi
IT1254280B (it) * 1992-03-13 1995-09-14 Fidia Spa Composizioni farmaceutiche comprendenti monosialoganglioside gm1 o un suo derivato atte al trattamento della malattia di parkinson
EP2473176A4 (en) * 2009-09-04 2013-03-06 Univ Alberta NEUROPROTECTIVE GANGLIOSIDE COMPOSITIONS FOR USE IN THE TREATMENT OR DIAGNOSIS OF HUNTINGTON DISEASE
ES2444269T3 (es) * 2010-07-23 2014-02-24 Loctite (R & D) Limited Método para la producción de anhídrido de ácido 2-cianoacético y otros productos de reacción correspondientes.

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK17885D0 (da) * 1985-01-14 1985-01-14 Karlsson Karl Anders Antiviralt middel
IT1182209B (it) * 1985-02-18 1987-09-30 Fidia Farmaceutici Uso terapeutico del monosialoganglioside gm1 e dei suoi derivati in gravi patologie di infarti cerebrali
NZ222192A (en) * 1986-10-20 1991-03-26 Kanto Ishi Pharma Co Ltd Glycolipid containing n-glycolylneuraminic acid, and preparation thereof
IT1235011B (it) * 1988-07-26 1992-06-16 Fidia Farmaceutici Sintesi di derivati di glicosfingolipidi ed in particolare di gangliosidi utilizzabili per la preparazione di immunoadsorbenti ed adsorbenti per affinita' impiegabili per la purificazione di anticorpi e di tossine specifiche, e per uso diagnostico
GB8827967D0 (en) * 1988-11-30 1989-01-05 Ward I M Die-free drawing
IN171530B (it) * 1989-11-17 1992-11-07 Fidia Spa

Also Published As

Publication number Publication date
EP0373039A2 (en) 1990-06-13
HU896337D0 (en) 1990-02-28
AU630384B2 (en) 1992-10-29
NO894820L (no) 1990-06-05
NO173141C (no) 1993-11-03
HUT53116A (en) 1990-09-28
FI895765A0 (fi) 1989-12-01
DE68914418T2 (de) 1994-10-06
ATE103926T1 (de) 1994-04-15
FI95577C (fi) 1996-02-26
IL92513A0 (en) 1990-08-31
KR910009721A (ko) 1991-06-28
IT8848618A0 (it) 1988-12-02
EP0373039B1 (en) 1994-04-06
CA2004189A1 (en) 1990-06-02
DK589889A (da) 1990-06-03
ES2063156T3 (es) 1995-01-01
FI95577B (fi) 1995-11-15
JPH02200697A (ja) 1990-08-08
NO894820D0 (no) 1989-12-01
AU4571889A (en) 1990-06-07
EP0373039A3 (en) 1991-06-05
DK589889D0 (da) 1989-11-23
DE68914418D1 (de) 1994-05-11
HU205129B (en) 1992-03-30
NZ231624A (en) 1992-03-26
NO173141B (no) 1993-07-26

Similar Documents

Publication Publication Date Title
FI895766A0 (fi) Foerfarande foer framstaellning av nya lysosfingolipider.
IT1235161B (it) Derivati di lisogangliosidi
PL286248A1 (en) Method of obtaining novel derivatives of gangliosides
FI903753A0 (fi) Foerfarande foer framstaellning av terapeutiskt anvaendbara halvsyntetiska gangliosidderivat.

Legal Events

Date Code Title Description
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19950925