ATE158297T1 - Halbsynthetische gangliosidanaloge - Google Patents

Halbsynthetische gangliosidanaloge

Info

Publication number
ATE158297T1
ATE158297T1 AT90402139T AT90402139T ATE158297T1 AT E158297 T1 ATE158297 T1 AT E158297T1 AT 90402139 T AT90402139 T AT 90402139T AT 90402139 T AT90402139 T AT 90402139T AT E158297 T1 ATE158297 T1 AT E158297T1
Authority
AT
Austria
Prior art keywords
acyl
dilysogangliosides
semi
derived
carbon atoms
Prior art date
Application number
AT90402139T
Other languages
English (en)
Inventor
Valle Francesco Della
Aurelio Romeo
Original Assignee
Fidia Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fidia Spa filed Critical Fidia Spa
Application granted granted Critical
Publication of ATE158297T1 publication Critical patent/ATE158297T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C07H15/10—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical containing unsaturated carbon-to-carbon bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biotechnology (AREA)
  • Public Health (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Lead Frames For Integrated Circuits (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
AT90402139T 1989-07-27 1990-07-25 Halbsynthetische gangliosidanaloge ATE158297T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8948246A IT1232175B (it) 1989-07-27 1989-07-27 Analoghi semisintetici di gangliosidi

Publications (1)

Publication Number Publication Date
ATE158297T1 true ATE158297T1 (de) 1997-10-15

Family

ID=11265466

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90402139T ATE158297T1 (de) 1989-07-27 1990-07-25 Halbsynthetische gangliosidanaloge

Country Status (16)

Country Link
US (1) US5484775A (de)
EP (1) EP0410881B1 (de)
JP (1) JPH0358995A (de)
KR (1) KR910002887A (de)
AT (1) ATE158297T1 (de)
AU (1) AU5982990A (de)
CA (1) CA2022138A1 (de)
DE (1) DE69031448T2 (de)
ES (1) ES2106025T3 (de)
FI (1) FI903753A0 (de)
HU (1) HU210923B (de)
IL (1) IL95169A0 (de)
IT (1) IT1232175B (de)
NO (1) NO903333L (de)
NZ (1) NZ234649A (de)
PL (1) PL165209B1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1232176B (it) * 1989-07-27 1992-01-25 Fidia Farmaceutici Derivati di-lisogangliosidi
IT1239060B (it) * 1990-05-04 1993-09-20 Fidia Spa Processo per la modulazione selettiva dell'espressione e della funzione di un determinante sulla superficie cellulare attraverso appropriati agenti chimici
IT1253832B (it) * 1991-08-01 1995-08-29 Fidia Spa Derivati di gangliosidi
DE4204907A1 (de) * 1992-02-14 1993-08-19 Reutter Werner Neuartige glykokonjugate mit n-substituierten neuraminsaeuren als mittel zur stimulierung des immunsystems
JP2005527467A (ja) 2001-08-29 2005-09-15 ネオーズ テクノロジーズ， インコーポレイテッド 新規な合成ガングリオシド誘導体およびその組成物
MXPA05009480A (es) 2003-03-06 2006-02-22 Neose Technologies Inc Metodos y composiciones para la sintesis enzimatica de gangliosidos.
EP3175857A1 (de) * 2009-03-25 2017-06-07 Seneb Biosciences Inc. Glycolipide zur behandlung von erkrankungen
UA127177C2 (uk) 2015-10-09 2023-05-31 ТЕНСАР КОРПОРЕЙШН, ЕлЕлСі Геосітка, виготовлена із співекструдованого багатошарового полімеру

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4476119A (en) * 1981-08-04 1984-10-09 Fidia S.P.A. Method for preparing ganglioside derivatives and use thereof in pharmaceutical compositions
US4593091A (en) * 1981-08-04 1986-06-03 Fidia, S.P.A. Method for preparing ganglioside derivatives and use thereof in pharmaceutical compositions
US4716223A (en) * 1981-08-04 1987-12-29 Fidia, S.P.A. Method for preparing ganglioside derivatives and use thereof in pharmaceutical compositions
IT1199116B (it) * 1984-07-03 1988-12-30 Fidia Farmaceutici Derivati di gangliosidi
JPH06795B2 (ja) * 1985-04-02 1994-01-05 理化学研究所 アシアロガングリオシド関連化合物の製造方法
US5010059A (en) * 1987-06-26 1991-04-23 Solco Basel Ag Pharmaceutical products and lactosyl compounds
IT1212041B (it) * 1987-11-02 1989-11-08 Fidia Farmaceutici Gangliosidi esteri interni come agenti terapeutici capaci di eliminare il dolore nelle neuropatie periferiche
CA1339488C (en) * 1988-02-12 1997-10-07 Taeko Dohi De-n-acetyl-syalic acid and their applications as modifiers of cell physiology
IT1235161B (it) * 1988-12-02 1992-06-22 Fidia Farmaceutici Derivati di lisogangliosidi
IT1253832B (it) * 1991-08-01 1995-08-29 Fidia Spa Derivati di gangliosidi

Also Published As

Publication number Publication date
JPH0358995A (ja) 1991-03-14
DE69031448T2 (de) 1998-02-26
CA2022138A1 (en) 1991-01-28
PL165209B1 (pl) 1994-11-30
EP0410881B1 (de) 1997-09-17
IT8948246A0 (it) 1989-07-27
US5484775A (en) 1996-01-16
HUT54173A (en) 1991-01-28
NZ234649A (en) 1992-01-29
FI903753A0 (fi) 1990-07-27
IL95169A0 (en) 1991-06-10
NO903333L (no) 1991-01-28
HU210923B (en) 1995-09-28
AU5982990A (en) 1991-01-31
KR910002887A (ko) 1991-02-26
PL286249A1 (en) 1991-08-26
IT1232175B (it) 1992-01-25
EP0410881A3 (en) 1993-01-20
HU904640D0 (en) 1991-01-28
NO903333D0 (no) 1990-07-26
ES2106025T3 (es) 1997-11-01
DE69031448D1 (de) 1997-10-23
EP0410881A2 (de) 1991-01-30

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