IT1208751B - Possibile uso dei gangliosidi esogeni in malattie tumorali come fattore protettivo contro la neurotossicita' da farmaci antitumorali - Google Patents
Possibile uso dei gangliosidi esogeni in malattie tumorali come fattore protettivo contro la neurotossicita' da farmaci antitumoraliInfo
- Publication number
- IT1208751B IT1208751B IT8648203A IT4820386A IT1208751B IT 1208751 B IT1208751 B IT 1208751B IT 8648203 A IT8648203 A IT 8648203A IT 4820386 A IT4820386 A IT 4820386A IT 1208751 B IT1208751 B IT 1208751B
- Authority
- IT
- Italy
- Prior art keywords
- possible use
- cancer diseases
- factor against
- protective factor
- against neurotoxicity
- Prior art date
Links
- 150000002270 gangliosides Chemical class 0.000 title abstract 2
- 206010028980 Neoplasm Diseases 0.000 title 1
- 206010029350 Neurotoxicity Diseases 0.000 title 1
- 206010044221 Toxic encephalopathy Diseases 0.000 title 1
- 230000000259 anti-tumor effect Effects 0.000 title 1
- 201000011510 cancer Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
- 230000007135 neurotoxicity Effects 0.000 title 1
- 231100000228 neurotoxicity Toxicity 0.000 title 1
- 230000001681 protective effect Effects 0.000 title 1
- 229940034982 antineoplastic agent Drugs 0.000 abstract 1
- 239000002246 antineoplastic agent Substances 0.000 abstract 1
- 230000001684 chronic effect Effects 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000002887 neurotoxic effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 231100000331 toxic Toxicity 0.000 abstract 1
- 230000002588 toxic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Priority Applications (18)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT8648203A IT1208751B (it) | 1986-06-30 | 1986-06-30 | Possibile uso dei gangliosidi esogeni in malattie tumorali come fattore protettivo contro la neurotossicita' da farmaci antitumorali |
| IL82944A IL82944A (en) | 1986-06-30 | 1987-06-22 | Pharmaceutical compositions comprising a ganglioside mixture for prophylaxis of general toxic effects or chronic neurotoxic effects |
| GR871005A GR871005B (en) | 1986-06-30 | 1987-06-25 | Possible use of exogenous gangliosides in tumoral diseases as a protective factor against toxicity by antitumor drugs |
| FR878708937A FR2601248B1 (fr) | 1986-06-30 | 1987-06-25 | Utilisation de gangliosides exogenes dans des maladies tumorales comme facteur de protection contre la toxicite de medicaments antitumoraux. |
| LU86930A LU86930A1 (fr) | 1986-06-30 | 1987-06-25 | Utilisation de gangliosides exogenes dens des maladies tumorales comme facteur de protection contre la toxite de medicaments antitumoraux |
| ZA874597A ZA874597B (en) | 1986-06-30 | 1987-06-25 | The use of exogenous gangliosides in tumoral diseases as a protective factor against toxicity by antitumoral drugs |
| US07/066,248 US5229373A (en) | 1986-06-30 | 1987-06-25 | Use of exogenous gangliosides as a protective factor against toxicity by antitumor drug vincristine |
| BE8700719A BE1000723A4 (fr) | 1986-06-30 | 1987-06-26 | Utilisation de gangliosides exogenes dans des maladies tumorales comme facteur de protection contre la toxicite de medicaments antitumoraux. |
| DK333787A DK165621C (da) | 1986-06-30 | 1987-06-29 | Anvendelse af gangliosidderivater til fremstilling af et farmaceutisk praeparat til forebyggelse af toxiske virkninger af antineoplastiske midler |
| AU74908/87A AU601988B2 (en) | 1986-06-30 | 1987-06-29 | The use of exogenous gangliosides in tumoral diseases as a protective factor against toxicity by antitumoral drugs |
| CA000540885A CA1314219C (en) | 1986-06-30 | 1987-06-29 | Use of exogenous gangliosides in tumoral diseases as a protective factor against toxicity by antitumoral drugs |
| AT87109415T ATE69381T1 (de) | 1986-06-30 | 1987-06-30 | Anwendung exogener ganglioside zur herstellung eines arzneimittels zur anwendung bei tumorkrankheiten als schutzmittel gegen die toxizitaet tumorhemmender arzneimittel. |
| DE19873721562 DE3721562A1 (de) | 1986-06-30 | 1987-06-30 | Verwendung exogener ganglioside als schutzfaktor bei tumorerkrankungen |
| ES198787109415T ES2038621T3 (es) | 1986-06-30 | 1987-06-30 | Utilizacion de gangliosidos exogenos para la preparacion de un medicamento a utilizar en enfermedades tumorales como factor de proteccion contra la toxicidad por medicamentos antitumorales. |
| JP62165131A JPS6327434A (ja) | 1986-06-30 | 1987-06-30 | ガングリオシドを含有する医薬 |
| EP87109415A EP0251298B1 (en) | 1986-06-30 | 1987-06-30 | Use of exogenous gangliosides for the preparation of a medicament for use in tumoral diseases as a protective factor against toxicity by antitumor drugs |
| DE8787109415T DE3774501D1 (de) | 1986-06-30 | 1987-06-30 | Anwendung exogener ganglioside zur herstellung eines arzneimittels zur anwendung bei tumorkrankheiten als schutzmittel gegen die toxizitaet tumorhemmender arzneimittel. |
| GR910402224T GR3003790T3 (it) | 1986-06-30 | 1992-02-12 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT8648203A IT1208751B (it) | 1986-06-30 | 1986-06-30 | Possibile uso dei gangliosidi esogeni in malattie tumorali come fattore protettivo contro la neurotossicita' da farmaci antitumorali |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IT8648203A0 IT8648203A0 (it) | 1986-06-30 |
| IT1208751B true IT1208751B (it) | 1989-07-10 |
Family
ID=11265194
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT8648203A IT1208751B (it) | 1986-06-30 | 1986-06-30 | Possibile uso dei gangliosidi esogeni in malattie tumorali come fattore protettivo contro la neurotossicita' da farmaci antitumorali |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US5229373A (it) |
| EP (1) | EP0251298B1 (it) |
| JP (1) | JPS6327434A (it) |
| AT (1) | ATE69381T1 (it) |
| AU (1) | AU601988B2 (it) |
| BE (1) | BE1000723A4 (it) |
| CA (1) | CA1314219C (it) |
| DE (2) | DE3721562A1 (it) |
| DK (1) | DK165621C (it) |
| ES (1) | ES2038621T3 (it) |
| FR (1) | FR2601248B1 (it) |
| GR (2) | GR871005B (it) |
| IL (1) | IL82944A (it) |
| IT (1) | IT1208751B (it) |
| LU (1) | LU86930A1 (it) |
| ZA (1) | ZA874597B (it) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1254280B (it) * | 1992-03-13 | 1995-09-14 | Fidia Spa | Composizioni farmaceutiche comprendenti monosialoganglioside gm1 o un suo derivato atte al trattamento della malattia di parkinson |
| US6765087B1 (en) * | 1992-08-21 | 2004-07-20 | Vrije Universiteit Brussel | Immunoglobulins devoid of light chains |
| DE4430041A1 (de) † | 1994-08-24 | 1996-02-29 | Milupa Ag | Allergieprotektive Formelnahrung |
| US5567684A (en) * | 1994-09-14 | 1996-10-22 | The Regents Of The University Of California | Synthetic ganglioside derivatives |
| WO2003017949A2 (en) | 2001-08-29 | 2003-03-06 | Neose Technologies, Inc. | Novel synthetic ganglioside derivatives and compositions thereof |
| MXPA05009480A (es) | 2003-03-06 | 2006-02-22 | Neose Technologies Inc | Metodos y composiciones para la sintesis enzimatica de gangliosidos. |
| JP2011518124A (ja) * | 2008-03-26 | 2011-06-23 | ユニバーシティ・オブ・オックスフォード | 小胞体ターゲッティングリポソーム |
| EP2410846B1 (en) | 2009-03-25 | 2016-09-07 | Seneb Biosciences, Inc. | Glycolipids as treatment for disease |
| WO2011027344A2 (en) * | 2009-09-01 | 2011-03-10 | Hadasit Medical Research Services And Development Ltd. | Combination of vitamin e and beta-glycosphingolipids in compositions and methods for preventing and treating hepatic disorders |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1168205B (it) * | 1983-07-21 | 1987-05-20 | Wellcome Italia | Derivato di monsialo ganglioside dotato di attivita' antibatterica, antifungina ed antitumorale, composizioni che lo contengono e procedimento per la loro preparazione |
| IT1182209B (it) * | 1985-02-18 | 1987-09-30 | Fidia Farmaceutici | Uso terapeutico del monosialoganglioside gm1 e dei suoi derivati in gravi patologie di infarti cerebrali |
-
1986
- 1986-06-30 IT IT8648203A patent/IT1208751B/it active
-
1987
- 1987-06-22 IL IL82944A patent/IL82944A/xx unknown
- 1987-06-25 US US07/066,248 patent/US5229373A/en not_active Expired - Fee Related
- 1987-06-25 LU LU86930A patent/LU86930A1/fr unknown
- 1987-06-25 GR GR871005A patent/GR871005B/el unknown
- 1987-06-25 FR FR878708937A patent/FR2601248B1/fr not_active Expired
- 1987-06-25 ZA ZA874597A patent/ZA874597B/xx unknown
- 1987-06-26 BE BE8700719A patent/BE1000723A4/fr not_active IP Right Cessation
- 1987-06-29 AU AU74908/87A patent/AU601988B2/en not_active Ceased
- 1987-06-29 CA CA000540885A patent/CA1314219C/en not_active Expired - Fee Related
- 1987-06-29 DK DK333787A patent/DK165621C/da not_active IP Right Cessation
- 1987-06-30 AT AT87109415T patent/ATE69381T1/de active
- 1987-06-30 ES ES198787109415T patent/ES2038621T3/es not_active Expired - Lifetime
- 1987-06-30 DE DE19873721562 patent/DE3721562A1/de not_active Withdrawn
- 1987-06-30 JP JP62165131A patent/JPS6327434A/ja active Pending
- 1987-06-30 EP EP87109415A patent/EP0251298B1/en not_active Expired - Lifetime
- 1987-06-30 DE DE8787109415T patent/DE3774501D1/de not_active Expired - Lifetime
-
1992
- 1992-02-12 GR GR910402224T patent/GR3003790T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FR2601248B1 (fr) | 1989-08-25 |
| DK165621C (da) | 1993-06-01 |
| IL82944A (en) | 1993-04-04 |
| AU7490887A (en) | 1988-01-07 |
| ATE69381T1 (de) | 1991-11-15 |
| DK333787D0 (da) | 1987-06-29 |
| ZA874597B (en) | 1988-03-30 |
| US5229373A (en) | 1993-07-20 |
| FR2601248A1 (fr) | 1988-01-15 |
| GR3003790T3 (it) | 1993-03-16 |
| JPS6327434A (ja) | 1988-02-05 |
| DE3774501D1 (de) | 1991-12-19 |
| DK333787A (da) | 1987-12-31 |
| EP0251298B1 (en) | 1991-11-13 |
| CA1314219C (en) | 1993-03-09 |
| ES2038621T3 (es) | 1993-08-01 |
| DE3721562A1 (de) | 1988-03-03 |
| DK165621B (da) | 1992-12-28 |
| IT8648203A0 (it) | 1986-06-30 |
| EP0251298A3 (en) | 1988-10-26 |
| LU86930A1 (fr) | 1987-11-11 |
| GR871005B (en) | 1987-10-23 |
| EP0251298A2 (en) | 1988-01-07 |
| AU601988B2 (en) | 1990-09-27 |
| BE1000723A4 (fr) | 1989-03-21 |
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