BE1000723A4 - Utilisation de gangliosides exogenes dans des maladies tumorales comme facteur de protection contre la toxicite de medicaments antitumoraux. - Google Patents
Utilisation de gangliosides exogenes dans des maladies tumorales comme facteur de protection contre la toxicite de medicaments antitumoraux. Download PDFInfo
- Publication number
- BE1000723A4 BE1000723A4 BE8700719A BE8700719A BE1000723A4 BE 1000723 A4 BE1000723 A4 BE 1000723A4 BE 8700719 A BE8700719 A BE 8700719A BE 8700719 A BE8700719 A BE 8700719A BE 1000723 A4 BE1000723 A4 BE 1000723A4
- Authority
- BE
- Belgium
- Prior art keywords
- tumor
- factor against
- protective factor
- against toxicity
- gangliosides
- Prior art date
Links
- 239000002246 antineoplastic agent Substances 0.000 title abstract 2
- 150000002270 gangliosides Chemical class 0.000 title abstract 2
- 206010028980 Neoplasm Diseases 0.000 title 1
- 229940041181 antineoplastic drug Drugs 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 230000001681 protective effect Effects 0.000 title 1
- 230000001988 toxicity Effects 0.000 title 1
- 231100000419 toxicity Toxicity 0.000 title 1
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 1
- 229940034982 antineoplastic agent Drugs 0.000 abstract 1
- 230000001684 chronic effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000001613 neoplastic effect Effects 0.000 abstract 1
- 230000002887 neurotoxic effect Effects 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 231100000331 toxic Toxicity 0.000 abstract 1
- 230000002588 toxic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Un agent de prévention et de prophylaxie des effets toxiques généraux ou des effets neurotoxiques chroniques occasionnés par l'administration d'agents antinéoplasiques, que l'on doit administrer aux patients avent l'administration de ces agents néoplasiques et qui comprend comme ingrédient actif un mélange de gangliosides GM1, GD1a, GD1b et GT1b.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT8648203A IT1208751B (it) | 1986-06-30 | 1986-06-30 | Possibile uso dei gangliosidi esogeni in malattie tumorali come fattore protettivo contro la neurotossicita' da farmaci antitumorali |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BE1000723A4 true BE1000723A4 (fr) | 1989-03-21 |
Family
ID=11265194
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BE8700719A BE1000723A4 (fr) | 1986-06-30 | 1987-06-26 | Utilisation de gangliosides exogenes dans des maladies tumorales comme facteur de protection contre la toxicite de medicaments antitumoraux. |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US5229373A (fr) |
| EP (1) | EP0251298B1 (fr) |
| JP (1) | JPS6327434A (fr) |
| AT (1) | ATE69381T1 (fr) |
| AU (1) | AU601988B2 (fr) |
| BE (1) | BE1000723A4 (fr) |
| CA (1) | CA1314219C (fr) |
| DE (2) | DE3774501D1 (fr) |
| DK (1) | DK165621C (fr) |
| ES (1) | ES2038621T3 (fr) |
| FR (1) | FR2601248B1 (fr) |
| GR (2) | GR871005B (fr) |
| IL (1) | IL82944A (fr) |
| IT (1) | IT1208751B (fr) |
| LU (1) | LU86930A1 (fr) |
| ZA (1) | ZA874597B (fr) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1254280B (it) * | 1992-03-13 | 1995-09-14 | Fidia Spa | Composizioni farmaceutiche comprendenti monosialoganglioside gm1 o un suo derivato atte al trattamento della malattia di parkinson |
| US6765087B1 (en) * | 1992-08-21 | 2004-07-20 | Vrije Universiteit Brussel | Immunoglobulins devoid of light chains |
| DE4430041A1 (de) † | 1994-08-24 | 1996-02-29 | Milupa Ag | Allergieprotektive Formelnahrung |
| US5567684A (en) * | 1994-09-14 | 1996-10-22 | The Regents Of The University Of California | Synthetic ganglioside derivatives |
| EP1435972B1 (fr) | 2001-08-29 | 2016-03-09 | Seneb Biosciences Inc. | Nouveaux dérivés synthétiques de ganglioside et compositions contenant ceux-ci |
| AU2004220087A1 (en) | 2003-03-06 | 2004-09-23 | Seneb Biosciences, Inc. | Methods and compositions for the enzymatic synthesis of gangliosides |
| WO2009118658A2 (fr) * | 2008-03-26 | 2009-10-01 | University Of Oxford | Liposomes ciblant le réticulum endoplasmique |
| EP2410846B1 (fr) | 2009-03-25 | 2016-09-07 | Seneb Biosciences, Inc. | Glycolipides en tant que traitement de maladies |
| WO2011027344A2 (fr) * | 2009-09-01 | 2011-03-10 | Hadasit Medical Research Services And Development Ltd. | Combinaison de vitamine e et de bêta-glycosphingolipides dans des compositions, méthodes de prévention et de traitement des troubles hépatiques |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1168205B (it) * | 1983-07-21 | 1987-05-20 | Wellcome Italia | Derivato di monsialo ganglioside dotato di attivita' antibatterica, antifungina ed antitumorale, composizioni che lo contengono e procedimento per la loro preparazione |
| IT1182209B (it) * | 1985-02-18 | 1987-09-30 | Fidia Farmaceutici | Uso terapeutico del monosialoganglioside gm1 e dei suoi derivati in gravi patologie di infarti cerebrali |
-
1986
- 1986-06-30 IT IT8648203A patent/IT1208751B/it active
-
1987
- 1987-06-22 IL IL82944A patent/IL82944A/xx unknown
- 1987-06-25 LU LU86930A patent/LU86930A1/fr unknown
- 1987-06-25 FR FR878708937A patent/FR2601248B1/fr not_active Expired
- 1987-06-25 ZA ZA874597A patent/ZA874597B/xx unknown
- 1987-06-25 US US07/066,248 patent/US5229373A/en not_active Expired - Fee Related
- 1987-06-25 GR GR871005A patent/GR871005B/el unknown
- 1987-06-26 BE BE8700719A patent/BE1000723A4/fr not_active IP Right Cessation
- 1987-06-29 CA CA000540885A patent/CA1314219C/fr not_active Expired - Fee Related
- 1987-06-29 AU AU74908/87A patent/AU601988B2/en not_active Ceased
- 1987-06-29 DK DK333787A patent/DK165621C/da not_active IP Right Cessation
- 1987-06-30 JP JP62165131A patent/JPS6327434A/ja active Pending
- 1987-06-30 DE DE8787109415T patent/DE3774501D1/de not_active Expired - Lifetime
- 1987-06-30 DE DE19873721562 patent/DE3721562A1/de not_active Withdrawn
- 1987-06-30 EP EP87109415A patent/EP0251298B1/fr not_active Expired - Lifetime
- 1987-06-30 ES ES198787109415T patent/ES2038621T3/es not_active Expired - Lifetime
- 1987-06-30 AT AT87109415T patent/ATE69381T1/de active
-
1992
- 1992-02-12 GR GR910402224T patent/GR3003790T3/el unknown
Non-Patent Citations (3)
| Title |
|---|
| Chemical Abstracts, vol. 107, no. 15, 12 octobre 1987 (Columbus, Ohio, US) K. Hellmann et al.: "Effect of high dose mitozantrone with Cronassial on the Lewis lung carcinoma and L1210 leukemia", voir page 26 * |
| Chemical Abstracts, vol. 108, no. 23, 6 juin 1988 (Columbus, Ohio, US) K. Hellmann et al.: "Mitozantrone therapeutic index improvement by gangliosides", voir page 25 * |
| Chemical Abstracts, vol. 108, no. 5, 1er fevrier 1988, (Columbus, Ohio, US) K. Hellmann et al.: "Reduction of vincristine toxicity by Cronassial", voir page 37 * |
Also Published As
| Publication number | Publication date |
|---|---|
| US5229373A (en) | 1993-07-20 |
| EP0251298B1 (fr) | 1991-11-13 |
| DK333787D0 (da) | 1987-06-29 |
| GR3003790T3 (fr) | 1993-03-16 |
| EP0251298A3 (en) | 1988-10-26 |
| GR871005B (en) | 1987-10-23 |
| DE3721562A1 (de) | 1988-03-03 |
| DK165621B (da) | 1992-12-28 |
| AU601988B2 (en) | 1990-09-27 |
| DK333787A (da) | 1987-12-31 |
| IL82944A (en) | 1993-04-04 |
| IT8648203A0 (it) | 1986-06-30 |
| AU7490887A (en) | 1988-01-07 |
| DE3774501D1 (de) | 1991-12-19 |
| DK165621C (da) | 1993-06-01 |
| CA1314219C (fr) | 1993-03-09 |
| ZA874597B (en) | 1988-03-30 |
| IT1208751B (it) | 1989-07-10 |
| JPS6327434A (ja) | 1988-02-05 |
| FR2601248A1 (fr) | 1988-01-15 |
| LU86930A1 (fr) | 1987-11-11 |
| ATE69381T1 (de) | 1991-11-15 |
| EP0251298A2 (fr) | 1988-01-07 |
| ES2038621T3 (es) | 1993-08-01 |
| FR2601248B1 (fr) | 1989-08-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RE | Patent lapsed |
Owner name: FIDIA S.P.A. Effective date: 19930630 |