DE69731834T2 - Agouti verwandtes gen - Google Patents
Agouti verwandtes gen Download PDFInfo
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- DE69731834T2 DE69731834T2 DE69731834T DE69731834T DE69731834T2 DE 69731834 T2 DE69731834 T2 DE 69731834T2 DE 69731834 T DE69731834 T DE 69731834T DE 69731834 T DE69731834 T DE 69731834T DE 69731834 T2 DE69731834 T2 DE 69731834T2
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- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 230000003319 supportive effect Effects 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 235000019818 tetrasodium diphosphate Nutrition 0.000 description 1
- 239000001577 tetrasodium phosphonato phosphate Substances 0.000 description 1
- 238000000293 three-dimensional nuclear magnetic resonance spectroscopy Methods 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 231100000167 toxic agent Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
- 230000007888 toxin activity Effects 0.000 description 1
- 238000001890 transfection Methods 0.000 description 1
- 238000011830 transgenic mouse model Methods 0.000 description 1
- 230000008733 trauma Effects 0.000 description 1
- 238000000108 ultra-filtration Methods 0.000 description 1
- 241000701161 unidentified adenovirus Species 0.000 description 1
- 241000701447 unidentified baculovirus Species 0.000 description 1
- 241001529453 unidentified herpesvirus Species 0.000 description 1
- 150000003673 urethanes Chemical class 0.000 description 1
- 230000003612 virological effect Effects 0.000 description 1
- 239000008215 water for injection Substances 0.000 description 1
- 238000001262 western blot Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Fats And Perfumes (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1750596P | 1996-05-10 | 1996-05-10 | |
| US17505P | 1996-05-10 | ||
| US757541 | 1996-11-27 | ||
| US08/757,541 US5766877A (en) | 1996-05-10 | 1996-11-27 | Genes encoding art, an agouti-related transcript |
| PCT/US1997/006853 WO1997043412A1 (en) | 1996-05-10 | 1997-04-22 | Novel agouti-related gene |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69731834D1 DE69731834D1 (de) | 2005-01-05 |
| DE69731834T2 true DE69731834T2 (de) | 2005-12-15 |
Family
ID=26689965
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69731834T Expired - Fee Related DE69731834T2 (de) | 1996-05-10 | 1997-04-22 | Agouti verwandtes gen |
Country Status (12)
| Country | Link |
|---|---|
| US (5) | US5766877A (enExample) |
| EP (1) | EP0917571B1 (enExample) |
| JP (1) | JP4219404B2 (enExample) |
| AT (1) | ATE283917T1 (enExample) |
| AU (1) | AU2681497A (enExample) |
| CA (1) | CA2253238C (enExample) |
| DE (1) | DE69731834T2 (enExample) |
| DK (1) | DK0917571T3 (enExample) |
| ES (1) | ES2234015T3 (enExample) |
| PT (1) | PT917571E (enExample) |
| SI (1) | SI0917571T1 (enExample) |
| WO (1) | WO1997043412A1 (enExample) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6310034B1 (en) | 1993-05-21 | 2001-10-30 | Ut-Battelle, Llc | Agouti polypeptide compositions |
| US5789651A (en) * | 1993-05-21 | 1998-08-04 | Martin Marietta Energy Systems, Inc. | Isolation and characterization of Agouti: a diabetes/obesity related gene |
| WO2002064091A2 (en) * | 2001-02-13 | 2002-08-22 | Palatin Technologies, Inc. | Melanocortin metallopeptides for treatment of sexual dysfunction |
| US5766877A (en) * | 1996-05-10 | 1998-06-16 | Amgen Inc. | Genes encoding art, an agouti-related transcript |
| AU5243798A (en) * | 1996-11-06 | 1998-05-29 | Children's Medical Center Corporation | Transgenic animal expressing a syndecan in the regions of hypothalamus |
| US6878520B1 (en) * | 1997-12-16 | 2005-04-12 | Merck & Co., Inc. | C-terminal region of agouti-related transcript (ART) protein |
| EP1040351B1 (en) * | 1997-12-16 | 2007-07-18 | Merck & Co., Inc. | C-terminal region of agouti-related transcript (art) protein |
| WO1999050295A2 (en) * | 1998-03-30 | 1999-10-07 | Gryphon Sciences | Agouti-related protein analogs and methods of use |
| US6689873B1 (en) | 1998-04-29 | 2004-02-10 | Merck & Co., Inc. | Nucleic acid encoding rat agouti related protein |
| EP1109830A4 (en) * | 1998-09-03 | 2002-09-11 | Millennium Pharm Inc | MELANOCORTIN 4 RECEPTOR AS A TARGET FOR THE IDENTIFICATION OF COMPOUNDS USED TO TREAT NARCOMANIA |
| US6603058B1 (en) | 1998-12-09 | 2003-08-05 | Oklahoma Medical Research Foundation | Non-human animal model for obesity and uses thereof |
| US6716810B1 (en) | 1998-12-09 | 2004-04-06 | Eleanor Roosevelt Institute | Composition and method for regulation of body weight and associated conditions |
| US6303749B1 (en) | 1999-01-29 | 2001-10-16 | Amgen Inc. | Agouti and agouti-related peptide analogs |
| US20030064921A1 (en) * | 1999-10-27 | 2003-04-03 | The Regents Of The University Of California | Methods and compounds for modulating melanocortin receptor ligand binding and activity |
| EP1125579A3 (en) | 2000-01-18 | 2003-01-02 | Pfizer Products Inc. | Uses of agrp-melanocortin receptor binding modulating compounds |
| US20020028897A1 (en) * | 2000-05-31 | 2002-03-07 | Johnson Lynda Kaye | Copolymers of ethylene and selected acrylate esters |
| PT1385823E (pt) | 2001-04-09 | 2007-01-31 | Novartis Vaccines & Diagnostic | Compostos de guanidino como agonistas do receptor de melanocortina-4 (r-mc4) |
| US20030207814A1 (en) * | 2002-02-04 | 2003-11-06 | Chiron Corporation | Novel guanidinyl derivatives |
| US20050124652A1 (en) * | 2002-02-04 | 2005-06-09 | Rustum Boyce | Guanidino compounds |
| US20030195187A1 (en) * | 2002-02-04 | 2003-10-16 | Chiron Corporation | Guanidino compounds |
| EP1487474A4 (en) * | 2002-02-25 | 2006-11-29 | Chiron Corp | INTRANASAL ADMINISTRATION OF MC4-R AGONISTS |
| DE60333937D1 (de) * | 2002-05-23 | 2010-10-07 | Novartis Vaccines & Diagnostic | Substituierte quinazolinone verbindungen |
| CA2488725A1 (en) * | 2002-07-03 | 2004-01-15 | Su Qian | Agouti-related protein deficient cells, non-human transgenic animals and methods of selecting compounds which regulate energy metabolism |
| JP2007501861A (ja) * | 2003-05-23 | 2007-02-01 | カイロン コーポレイション | Ｍｃ４−ｒアゴニストとしてのグアニジノ置換キナゾリノン化合物 |
| ES2391457T3 (es) * | 2003-08-13 | 2012-11-26 | Sandoz Ag | Procedimiento para la purificación de polipéptidos recombinantes |
| US7368453B2 (en) * | 2003-11-19 | 2008-05-06 | Chiron Corporation | Quinazolinone compounds with reduced bioaccumulation |
| US6974187B2 (en) * | 2004-01-28 | 2005-12-13 | Tachi-S Co., Ltd. | Vehicle seat structure |
| JP4879165B2 (ja) * | 2004-04-20 | 2012-02-22 | トランス テック ファーマ，インコーポレイテッド | メラノコルチン受容体の調節因子としての置換チアゾール及びピリミジン誘導体 |
| US7910101B2 (en) | 2004-10-25 | 2011-03-22 | Centocor, Inc. | Melanocortin receptor binding mimetibodies, compositions, methods and uses |
| US20070021433A1 (en) | 2005-06-03 | 2007-01-25 | Jian-Qiang Fan | Pharmacological chaperones for treating obesity |
| US7833927B2 (en) * | 2005-08-31 | 2010-11-16 | Rohm And Haas Company | Single site palladium catalyst complexes |
| CA2731442A1 (en) * | 2008-08-29 | 2010-03-04 | Transtech Pharma, Inc. | Substituted aminothiazole derivatives, pharmaceutical compositions, and methods of use |
| CA2825098C (en) | 2011-01-27 | 2020-03-10 | Universite De Montreal | Pyrazolopyridine and pyrazolopyrimidine derivatives as melanocortin-4 receptor modulators |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3773919A (en) * | 1969-10-23 | 1973-11-20 | Du Pont | Polylactide-drug mixtures |
| US4263428A (en) * | 1978-03-24 | 1981-04-21 | The Regents Of The University Of California | Bis-anthracycline nucleic acid function inhibitors and improved method for administering the same |
| EP0052322B1 (de) * | 1980-11-10 | 1985-03-27 | Gersonde, Klaus, Prof. Dr. | Verfahren zur Herstellung von Lipid-Vesikeln durch Ultraschallbehandlung, Anwendung des Verfahrens und Vorrichtung zur Durchführung des Verfahrens |
| IE52535B1 (en) * | 1981-02-16 | 1987-12-09 | Ici Plc | Continuous release pharmaceutical compositions |
| DE3374837D1 (en) * | 1982-02-17 | 1988-01-21 | Ciba Geigy Ag | Lipids in the aqueous phase |
| DE3474511D1 (en) * | 1983-11-01 | 1988-11-17 | Terumo Corp | Pharmaceutical composition containing urokinase |
| DE3572982D1 (en) * | 1984-03-06 | 1989-10-19 | Takeda Chemical Industries Ltd | Chemically modified lymphokine and production thereof |
| CA2006596C (en) * | 1988-12-22 | 2000-09-05 | Rika Ishikawa | Chemically-modified g-csf |
| US5252714A (en) * | 1990-11-28 | 1993-10-12 | The University Of Alabama In Huntsville | Preparation and use of polyethylene glycol propionaldehyde |
| US5766877A (en) * | 1996-05-10 | 1998-06-16 | Amgen Inc. | Genes encoding art, an agouti-related transcript |
-
1996
- 1996-11-27 US US08/757,541 patent/US5766877A/en not_active Expired - Lifetime
-
1997
- 1997-04-22 DK DK97918802T patent/DK0917571T3/da active
- 1997-04-22 AT AT97918802T patent/ATE283917T1/de not_active IP Right Cessation
- 1997-04-22 ES ES97918802T patent/ES2234015T3/es not_active Expired - Lifetime
- 1997-04-22 PT PT97918802T patent/PT917571E/pt unknown
- 1997-04-22 JP JP54088297A patent/JP4219404B2/ja not_active Expired - Fee Related
- 1997-04-22 DE DE69731834T patent/DE69731834T2/de not_active Expired - Fee Related
- 1997-04-22 SI SI9730696T patent/SI0917571T1/xx unknown
- 1997-04-22 WO PCT/US1997/006853 patent/WO1997043412A1/en not_active Ceased
- 1997-04-22 EP EP97918802A patent/EP0917571B1/en not_active Expired - Lifetime
- 1997-04-22 CA CA002253238A patent/CA2253238C/en not_active Expired - Fee Related
- 1997-04-22 AU AU26814/97A patent/AU2681497A/en not_active Abandoned
-
1998
- 1998-03-02 US US09/033,275 patent/US6060589A/en not_active Expired - Fee Related
-
1999
- 1999-06-29 US US09/342,581 patent/US6203995B1/en not_active Expired - Fee Related
-
2001
- 2001-01-05 US US09/754,862 patent/US20010007752A1/en not_active Abandoned
-
2002
- 2002-09-27 US US10/256,590 patent/US7122520B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| ES2234015T3 (es) | 2005-06-16 |
| US20030082737A1 (en) | 2003-05-01 |
| US5766877A (en) | 1998-06-16 |
| CA2253238A1 (en) | 1997-11-20 |
| JP4219404B2 (ja) | 2009-02-04 |
| US20010007752A1 (en) | 2001-07-12 |
| EP0917571A1 (en) | 1999-05-26 |
| EP0917571B1 (en) | 2004-12-01 |
| JP2001517931A (ja) | 2001-10-09 |
| SI0917571T1 (en) | 2005-06-30 |
| US6203995B1 (en) | 2001-03-20 |
| DK0917571T3 (da) | 2005-03-14 |
| US6060589A (en) | 2000-05-09 |
| PT917571E (pt) | 2005-04-29 |
| AU2681497A (en) | 1997-12-05 |
| WO1997043412A1 (en) | 1997-11-20 |
| US7122520B2 (en) | 2006-10-17 |
| CA2253238C (en) | 2008-08-12 |
| ATE283917T1 (de) | 2004-12-15 |
| DE69731834D1 (de) | 2005-01-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |