JP4219404B2 - 新規なアグーティ関連遺伝子 - Google Patents

新規なアグーティ関連遺伝子 Download PDF

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Publication number
JP4219404B2
JP4219404B2 JP54088297A JP54088297A JP4219404B2 JP 4219404 B2 JP4219404 B2 JP 4219404B2 JP 54088297 A JP54088297 A JP 54088297A JP 54088297 A JP54088297 A JP 54088297A JP 4219404 B2 JP4219404 B2 JP 4219404B2
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Japan
Prior art keywords
seq
art
polypeptide
nucleic acid
acid molecule
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JP54088297A
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Japanese (ja)
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JP2001517931A (ja
JP2001517931A5 (enExample
Inventor
スターク，ケビン・リー
ルーシー，ローランド
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アムジエン・インコーポレーテツド
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Publication of JP2001517931A5 publication Critical patent/JP2001517931A5/ja
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Fats And Perfumes (AREA)
JP54088297A 1996-05-10 1997-04-22 新規なアグーティ関連遺伝子 Expired - Fee Related JP4219404B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US1750596P 1996-05-10 1996-05-10
US60/017,505 1996-05-10
US08/757,541 1996-11-27
US08/757,541 US5766877A (en) 1996-05-10 1996-11-27 Genes encoding art, an agouti-related transcript
PCT/US1997/006853 WO1997043412A1 (en) 1996-05-10 1997-04-22 Novel agouti-related gene

Publications (3)

Publication Number Publication Date
JP2001517931A JP2001517931A (ja) 2001-10-09
JP2001517931A5 JP2001517931A5 (enExample) 2004-12-09
JP4219404B2 true JP4219404B2 (ja) 2009-02-04

Family

ID=26689965

Family Applications (1)

Application Number Title Priority Date Filing Date
JP54088297A Expired - Fee Related JP4219404B2 (ja) 1996-05-10 1997-04-22 新規なアグーティ関連遺伝子

Country Status (12)

Country Link
US (5) US5766877A (enExample)
EP (1) EP0917571B1 (enExample)
JP (1) JP4219404B2 (enExample)
AT (1) ATE283917T1 (enExample)
AU (1) AU2681497A (enExample)
CA (1) CA2253238C (enExample)
DE (1) DE69731834T2 (enExample)
DK (1) DK0917571T3 (enExample)
ES (1) ES2234015T3 (enExample)
PT (1) PT917571E (enExample)
SI (1) SI0917571T1 (enExample)
WO (1) WO1997043412A1 (enExample)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6310034B1 (en) 1993-05-21 2001-10-30 Ut-Battelle, Llc Agouti polypeptide compositions
US5789651A (en) * 1993-05-21 1998-08-04 Martin Marietta Energy Systems, Inc. Isolation and characterization of Agouti: a diabetes/obesity related gene
WO2002064091A2 (en) * 2001-02-13 2002-08-22 Palatin Technologies, Inc. Melanocortin metallopeptides for treatment of sexual dysfunction
US5766877A (en) * 1996-05-10 1998-06-16 Amgen Inc. Genes encoding art, an agouti-related transcript
AU5243798A (en) * 1996-11-06 1998-05-29 Children's Medical Center Corporation Transgenic animal expressing a syndecan in the regions of hypothalamus
US6878520B1 (en) * 1997-12-16 2005-04-12 Merck & Co., Inc. C-terminal region of agouti-related transcript (ART) protein
EP1040351B1 (en) * 1997-12-16 2007-07-18 Merck & Co., Inc. C-terminal region of agouti-related transcript (art) protein
WO1999050295A2 (en) * 1998-03-30 1999-10-07 Gryphon Sciences Agouti-related protein analogs and methods of use
US6689873B1 (en) 1998-04-29 2004-02-10 Merck & Co., Inc. Nucleic acid encoding rat agouti related protein
EP1109830A4 (en) * 1998-09-03 2002-09-11 Millennium Pharm Inc MELANOCORTIN 4 RECEPTOR AS A TARGET FOR THE IDENTIFICATION OF COMPOUNDS USED TO TREAT NARCOMANIA
US6603058B1 (en) 1998-12-09 2003-08-05 Oklahoma Medical Research Foundation Non-human animal model for obesity and uses thereof
US6716810B1 (en) 1998-12-09 2004-04-06 Eleanor Roosevelt Institute Composition and method for regulation of body weight and associated conditions
US6303749B1 (en) 1999-01-29 2001-10-16 Amgen Inc. Agouti and agouti-related peptide analogs
US20030064921A1 (en) * 1999-10-27 2003-04-03 The Regents Of The University Of California Methods and compounds for modulating melanocortin receptor ligand binding and activity
EP1125579A3 (en) 2000-01-18 2003-01-02 Pfizer Products Inc. Uses of agrp-melanocortin receptor binding modulating compounds
US20020028897A1 (en) * 2000-05-31 2002-03-07 Johnson Lynda Kaye Copolymers of ethylene and selected acrylate esters
PT1385823E (pt) 2001-04-09 2007-01-31 Novartis Vaccines & Diagnostic Compostos de guanidino como agonistas do receptor de melanocortina-4 (r-mc4)
US20030207814A1 (en) * 2002-02-04 2003-11-06 Chiron Corporation Novel guanidinyl derivatives
US20050124652A1 (en) * 2002-02-04 2005-06-09 Rustum Boyce Guanidino compounds
US20030195187A1 (en) * 2002-02-04 2003-10-16 Chiron Corporation Guanidino compounds
EP1487474A4 (en) * 2002-02-25 2006-11-29 Chiron Corp INTRANASAL ADMINISTRATION OF MC4-R AGONISTS
DE60333937D1 (de) * 2002-05-23 2010-10-07 Novartis Vaccines & Diagnostic Substituierte quinazolinone verbindungen
CA2488725A1 (en) * 2002-07-03 2004-01-15 Su Qian Agouti-related protein deficient cells, non-human transgenic animals and methods of selecting compounds which regulate energy metabolism
JP2007501861A (ja) * 2003-05-23 2007-02-01 カイロン コーポレイション Ｍｃ４−ｒアゴニストとしてのグアニジノ置換キナゾリノン化合物
ES2391457T3 (es) * 2003-08-13 2012-11-26 Sandoz Ag Procedimiento para la purificación de polipéptidos recombinantes
US7368453B2 (en) * 2003-11-19 2008-05-06 Chiron Corporation Quinazolinone compounds with reduced bioaccumulation
US6974187B2 (en) * 2004-01-28 2005-12-13 Tachi-S Co., Ltd. Vehicle seat structure
JP4879165B2 (ja) * 2004-04-20 2012-02-22 トランス テック ファーマ，インコーポレイテッド メラノコルチン受容体の調節因子としての置換チアゾール及びピリミジン誘導体
US7910101B2 (en) 2004-10-25 2011-03-22 Centocor, Inc. Melanocortin receptor binding mimetibodies, compositions, methods and uses
US20070021433A1 (en) 2005-06-03 2007-01-25 Jian-Qiang Fan Pharmacological chaperones for treating obesity
US7833927B2 (en) * 2005-08-31 2010-11-16 Rohm And Haas Company Single site palladium catalyst complexes
CA2731442A1 (en) * 2008-08-29 2010-03-04 Transtech Pharma, Inc. Substituted aminothiazole derivatives, pharmaceutical compositions, and methods of use
CA2825098C (en) 2011-01-27 2020-03-10 Universite De Montreal Pyrazolopyridine and pyrazolopyrimidine derivatives as melanocortin-4 receptor modulators

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3773919A (en) * 1969-10-23 1973-11-20 Du Pont Polylactide-drug mixtures
US4263428A (en) * 1978-03-24 1981-04-21 The Regents Of The University Of California Bis-anthracycline nucleic acid function inhibitors and improved method for administering the same
EP0052322B1 (de) * 1980-11-10 1985-03-27 Gersonde, Klaus, Prof. Dr. Verfahren zur Herstellung von Lipid-Vesikeln durch Ultraschallbehandlung, Anwendung des Verfahrens und Vorrichtung zur Durchführung des Verfahrens
IE52535B1 (en) * 1981-02-16 1987-12-09 Ici Plc Continuous release pharmaceutical compositions
DE3374837D1 (en) * 1982-02-17 1988-01-21 Ciba Geigy Ag Lipids in the aqueous phase
DE3474511D1 (en) * 1983-11-01 1988-11-17 Terumo Corp Pharmaceutical composition containing urokinase
DE3572982D1 (en) * 1984-03-06 1989-10-19 Takeda Chemical Industries Ltd Chemically modified lymphokine and production thereof
CA2006596C (en) * 1988-12-22 2000-09-05 Rika Ishikawa Chemically-modified g-csf
US5252714A (en) * 1990-11-28 1993-10-12 The University Of Alabama In Huntsville Preparation and use of polyethylene glycol propionaldehyde
US5766877A (en) * 1996-05-10 1998-06-16 Amgen Inc. Genes encoding art, an agouti-related transcript

Also Published As

Publication number Publication date
ES2234015T3 (es) 2005-06-16
US20030082737A1 (en) 2003-05-01
US5766877A (en) 1998-06-16
CA2253238A1 (en) 1997-11-20
US20010007752A1 (en) 2001-07-12
EP0917571A1 (en) 1999-05-26
EP0917571B1 (en) 2004-12-01
JP2001517931A (ja) 2001-10-09
SI0917571T1 (en) 2005-06-30
US6203995B1 (en) 2001-03-20
DK0917571T3 (da) 2005-03-14
US6060589A (en) 2000-05-09
PT917571E (pt) 2005-04-29
AU2681497A (en) 1997-12-05
WO1997043412A1 (en) 1997-11-20
DE69731834T2 (de) 2005-12-15
US7122520B2 (en) 2006-10-17
CA2253238C (en) 2008-08-12
ATE283917T1 (de) 2004-12-15
DE69731834D1 (de) 2005-01-05

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