DE69714448D1 - Verfahren zur herstellung von präparaten mit kontrollierter wirkstofffreisetzung auf basis von polymeren - Google Patents

Verfahren zur herstellung von präparaten mit kontrollierter wirkstofffreisetzung auf basis von polymeren

Info

Publication number
DE69714448D1
DE69714448D1 DE69714448T DE69714448T DE69714448D1 DE 69714448 D1 DE69714448 D1 DE 69714448D1 DE 69714448 T DE69714448 T DE 69714448T DE 69714448 T DE69714448 T DE 69714448T DE 69714448 D1 DE69714448 D1 DE 69714448D1
Authority
DE
Germany
Prior art keywords
polymer
drug
polymers
active substance
substance release
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69714448T
Other languages
English (en)
Other versions
DE69714448T2 (de
Inventor
A Burke
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alkermes Inc
Alkermes Controlled Therapeutics Inc
Original Assignee
Alkermes Inc
Alkermes Controlled Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alkermes Inc, Alkermes Controlled Therapeutics Inc filed Critical Alkermes Inc
Publication of DE69714448D1 publication Critical patent/DE69714448D1/de
Application granted granted Critical
Publication of DE69714448T2 publication Critical patent/DE69714448T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1816—Erythropoietin [EPO]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Dermatology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Neurosurgery (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
  • Polymerisation Methods In General (AREA)
  • Processing And Handling Of Plastics And Other Materials For Molding In General (AREA)
DE69714448T 1996-05-14 1997-05-01 Verfahren zur herstellung von präparaten mit kontrollierter wirkstofffreisetzung auf basis von polymeren Expired - Fee Related DE69714448T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/649,128 US5817343A (en) 1996-05-14 1996-05-14 Method for fabricating polymer-based controlled-release devices
PCT/US1997/007441 WO1997042940A1 (en) 1996-05-14 1997-05-01 Method for fabricating polymer-based controlled-release devices

Publications (2)

Publication Number Publication Date
DE69714448D1 true DE69714448D1 (de) 2002-09-05
DE69714448T2 DE69714448T2 (de) 2002-11-14

Family

ID=24603582

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69714448T Expired - Fee Related DE69714448T2 (de) 1996-05-14 1997-05-01 Verfahren zur herstellung von präparaten mit kontrollierter wirkstofffreisetzung auf basis von polymeren

Country Status (11)

Country Link
US (3) US5817343A (de)
EP (1) EP0914095B1 (de)
JP (1) JP2000513333A (de)
AT (1) ATE221373T1 (de)
AU (1) AU718866B2 (de)
CA (1) CA2253667A1 (de)
DE (1) DE69714448T2 (de)
DK (1) DK0914095T3 (de)
ES (1) ES2180982T3 (de)
PT (1) PT914095E (de)
WO (1) WO1997042940A1 (de)

Families Citing this family (174)

* Cited by examiner, † Cited by third party
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US20030031701A1 (en) 2003-02-13
AU718866B2 (en) 2000-04-20
PT914095E (pt) 2002-11-29
EP0914095B1 (de) 2002-07-31
JP2000513333A (ja) 2000-10-10
CA2253667A1 (en) 1997-11-20
ES2180982T3 (es) 2003-02-16
US6183781B1 (en) 2001-02-06
WO1997042940A1 (en) 1997-11-20
DK0914095T3 (da) 2002-11-11
AU2751797A (en) 1997-12-05
EP0914095A1 (de) 1999-05-12
DE69714448T2 (de) 2002-11-14
US5817343A (en) 1998-10-06

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