DE69634398D1 - Verfahren zur Herstellung einer festen Zubereitung, beschichtet mit einem lösungsmittelfreien Überzug - Google Patents

Verfahren zur Herstellung einer festen Zubereitung, beschichtet mit einem lösungsmittelfreien Überzug

Info

Publication number
DE69634398D1
DE69634398D1 DE69634398T DE69634398T DE69634398D1 DE 69634398 D1 DE69634398 D1 DE 69634398D1 DE 69634398 T DE69634398 T DE 69634398T DE 69634398 T DE69634398 T DE 69634398T DE 69634398 D1 DE69634398 D1 DE 69634398D1
Authority
DE
Germany
Prior art keywords
preparation
coated
solventless coating
solid
solid preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69634398T
Other languages
English (en)
Other versions
DE69634398T2 (de
Inventor
Naosuke Maruyama
Yuichi Nishiyama
Hiroyasu Kokubo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shin Etsu Chemical Co Ltd
Original Assignee
Shin Etsu Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shin Etsu Chemical Co Ltd filed Critical Shin Etsu Chemical Co Ltd
Publication of DE69634398D1 publication Critical patent/DE69634398D1/de
Application granted granted Critical
Publication of DE69634398T2 publication Critical patent/DE69634398T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5015—Organic compounds, e.g. fats, sugars
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
DE69634398T 1995-12-25 1996-12-19 Verfahren zur Herstellung einer festen Zubereitung, beschichtet mit einem lösungsmittelfreien Überzug Expired - Lifetime DE69634398T2 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP35094495 1995-12-25
JP35094495 1995-12-25
JP20892096 1996-07-19
JP20892096 1996-07-19

Publications (2)

Publication Number Publication Date
DE69634398D1 true DE69634398D1 (de) 2005-04-07
DE69634398T2 DE69634398T2 (de) 2005-12-29

Family

ID=26517123

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69634398T Expired - Lifetime DE69634398T2 (de) 1995-12-25 1996-12-19 Verfahren zur Herstellung einer festen Zubereitung, beschichtet mit einem lösungsmittelfreien Überzug

Country Status (4)

Country Link
US (1) US5789014A (de)
EP (1) EP0781549B1 (de)
KR (1) KR100420269B1 (de)
DE (1) DE69634398T2 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA69413C2 (uk) 1998-05-22 2004-09-15 Брістол-Майерс Сквібб Компані Фармацевтична композиція, яка містить серцевину та ентеросолюбільну оболонку, фармацевтична композиція у вигляді сфероїдальних гранул, спосіб одержання сфероїдальних гранул та спосіб одержання фармацевтичної композиції
US7122207B2 (en) 1998-05-22 2006-10-17 Bristol-Myers Squibb Company High drug load acid labile pharmaceutical composition
UA73092C2 (uk) 1998-07-17 2005-06-15 Брістол-Майерс Сквібб Компані Таблетка з ентеросолюбільним покриттям і спосіб її приготування
US6274162B1 (en) 2000-01-14 2001-08-14 Bpsi Holdings, Inc. Elegant film coating system
US6448323B1 (en) * 1999-07-09 2002-09-10 Bpsi Holdings, Inc. Film coatings and film coating compositions based on polyvinyl alcohol
US20020119196A1 (en) * 2000-12-21 2002-08-29 Narendra Parikh Texture masked particles containing an active ingredient
US6564454B1 (en) * 2000-12-28 2003-05-20 Amkor Technology, Inc. Method of making and stacking a semiconductor package
JP4644397B2 (ja) * 2001-09-05 2011-03-02 信越化学工業株式会社 難溶性薬物を含む医薬用固形製剤の製造方法
JP2004339162A (ja) * 2003-05-16 2004-12-02 Shin Etsu Chem Co Ltd 難溶性薬物を含む医薬用固形製剤とその製造方法
US7065440B2 (en) * 2004-01-22 2006-06-20 Trimble Navigation, Ltd Method and apparatus for steering movable object by using control algorithm that takes into account the difference between the nominal and optimum positions of navigation antenna
WO2005115341A2 (en) * 2004-05-27 2005-12-08 Advanced Bionutrition Corporation Microparticles for oral delivery
US20090252988A1 (en) * 2008-04-04 2009-10-08 Honeywell International Inc. Coated components for use in high temperature environments and methods of forming a coating on the component
CN102427740B (zh) * 2009-03-26 2016-02-03 先进生物营养公司 生物活性物质的微囊化及其制造方法

Family Cites Families (33)

* Cited by examiner, † Cited by third party
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US3524756A (en) * 1967-05-29 1970-08-18 Colorcon Process of coating tablets with alternate tacky and non-tacky layers
JPS597363B2 (ja) 1979-07-13 1984-02-17 旭光学工業株式会社 コンパクトなズ−ムレンズ系
JPS5855125B2 (ja) * 1980-03-10 1983-12-08 信越化学工業株式会社 固形薬剤用腸溶性コ−テイング剤組成物
JPS6056122B2 (ja) 1980-05-21 1985-12-09 塩野義製薬株式会社 徐放性製剤
JPS6054803B2 (ja) 1980-09-18 1985-12-02 新日本製鐵株式会社 多層管の連続製造方法
JPS57171428A (en) * 1981-04-13 1982-10-22 Sankyo Co Ltd Preparation of coated solid preparation
JPS5846019A (ja) 1981-09-14 1983-03-17 Kanebo Ltd 持続性ニフエジピン製剤
JPS5855125A (ja) 1981-09-29 1983-04-01 Kobe Steel Ltd 溶接用ワイヤの巻取り方法
JPS5920219A (ja) 1982-07-26 1984-02-01 Shin Etsu Chem Co Ltd 腸溶性コ−テイング製剤の製造方法
US4581381A (en) * 1983-11-14 1986-04-08 Nabisco Brands, Inc. Soft homogeneous antacid tablet
US4643894A (en) * 1984-07-24 1987-02-17 Colorcon, Inc. Maltodextrin coating
EP0184910B1 (de) * 1984-11-15 1992-09-30 Hercon Laboratories Corporation Vorrichtung zur kontrollierten Abgabe von Arzneimittelwirkstoffen
US4600645A (en) * 1985-01-31 1986-07-15 Warner-Lambert Company Process for treating dosage forms
JPS6233128A (ja) 1985-08-07 1987-02-13 Toray Ind Inc インタ−フエロン腸溶性経口用製剤
SE457326B (sv) * 1986-02-14 1988-12-19 Lejus Medical Ab Foerfarande foer framstaellning av en snabbt soenderfallande kaerna innehaallande bl a mikrokristallin cellulosa
JPS62195323A (ja) * 1986-02-24 1987-08-28 Eisai Co Ltd 胃内滞留型粒子
JPS6340131A (ja) 1986-08-06 1988-02-20 Canon Inc カラ−画像原稿照明光源装置
US4786503A (en) * 1987-04-06 1988-11-22 Alza Corporation Dosage form comprising parallel lamine
DE3721721C1 (de) * 1987-07-01 1988-06-09 Hoechst Ag Verfahren zur Umhuellung von Granulaten
US4894231A (en) * 1987-07-28 1990-01-16 Biomeasure, Inc. Therapeutic agent delivery system
JPH01287019A (ja) 1988-05-12 1989-11-17 Tanabe Seiyaku Co Ltd 徐放性製剤
JPH01287021A (ja) 1988-05-13 1989-11-17 Shin Etsu Chem Co Ltd ワックス複覆薬剤の製造方法
JPH0649654B2 (ja) 1988-11-24 1994-06-29 日本油脂株式会社 高安定性腸内有用細菌製剤及びその製造方法
JP2731862B2 (ja) 1989-05-08 1998-03-25 富山化学工業株式会社 持続性製剤用組成物およびその製造法
CA2011684C (en) * 1989-07-31 2000-05-02 Lawrence J. Daher Aqueous film coating
FR2655266B1 (fr) * 1989-12-05 1992-04-03 Smith Kline French Lab Compositions pharmaceutiques a base de cimetidine.
WO1991015548A1 (en) * 1990-04-04 1991-10-17 Berwind Pharmaceutical Services, Inc. Aqueous maltodextrin and cellulosic polymer film coatings
EP0452862B1 (de) * 1990-04-18 1995-07-19 Asahi Kasei Kogyo Kabushiki Kaisha Kugelförmige Keimkerne, kugelförmige Granulate sowie Verfahren zu deren Herstellung
FR2663867B1 (fr) * 1990-06-29 1994-08-05 Rhone Poulenc Nutrition Animal Procede de lissage de granules de principes actifs.
US5132142A (en) * 1991-03-19 1992-07-21 Glatt Gmbh Apparatus and method for producing pellets by layering power onto particles
CA2110899C (en) * 1991-06-21 2006-08-08 Jacob G. Michael Orally administrable therapeutic proteins and method of making
KR19990008430A (ko) * 1995-05-09 1999-01-25 피터 존스 팔슨즈 약재를 정전코팅하기 위한 분말코팅조성물
JP3471977B2 (ja) * 1995-06-02 2003-12-02 信越化学工業株式会社 液体状可塑剤を用いる無溶媒腸溶性コーティング剤で被覆した腸溶性製剤

Also Published As

Publication number Publication date
EP0781549A3 (de) 1999-05-06
EP0781549A2 (de) 1997-07-02
DE69634398T2 (de) 2005-12-29
US5789014A (en) 1998-08-04
KR970032847A (ko) 1997-07-22
EP0781549B1 (de) 2005-03-02
KR100420269B1 (ko) 2004-05-24

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