DE69611766T2 - Spezifische Bindungspartner für menschliches TGF-beta, Materialien und Verfahren - Google Patents
Spezifische Bindungspartner für menschliches TGF-beta, Materialien und VerfahrenInfo
- Publication number
- DE69611766T2 DE69611766T2 DE69611766T DE69611766T DE69611766T2 DE 69611766 T2 DE69611766 T2 DE 69611766T2 DE 69611766 T DE69611766 T DE 69611766T DE 69611766 T DE69611766 T DE 69611766T DE 69611766 T2 DE69611766 T2 DE 69611766T2
- Authority
- DE
- Germany
- Prior art keywords
- antibody
- specific binding
- tgfβ
- tgfβ2
- domain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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Landscapes
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9520486.3A GB9520486D0 (en) | 1995-10-06 | 1995-10-06 | Specific binding members for human transforming growth factor beta; materials and methods |
| GBGB9601081.4A GB9601081D0 (en) | 1995-10-06 | 1996-01-19 | Specific binding members for human transforming growth factor beta;materials and methods |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69611766D1 DE69611766D1 (de) | 2001-03-15 |
| DE69611766T2 true DE69611766T2 (de) | 2001-08-02 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69607191T Expired - Lifetime DE69607191T2 (de) | 1995-10-06 | 1996-10-07 | Spezifische bindungspartner für menschlichen transformierenden wachstumsfaktor und verfahren |
| DE69611766T Expired - Lifetime DE69611766T2 (de) | 1995-10-06 | 1996-10-07 | Spezifische Bindungspartner für menschliches TGF-beta, Materialien und Verfahren |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69607191T Expired - Lifetime DE69607191T2 (de) | 1995-10-06 | 1996-10-07 | Spezifische bindungspartner für menschlichen transformierenden wachstumsfaktor und verfahren |
Country Status (12)
| Country | Link |
|---|---|
| EP (2) | EP0945464B1 (OSRAM) |
| JP (1) | JP4387458B2 (OSRAM) |
| AT (2) | ATE199091T1 (OSRAM) |
| AU (1) | AU702049B2 (OSRAM) |
| CA (2) | CA2233042C (OSRAM) |
| DE (2) | DE69607191T2 (OSRAM) |
| DK (2) | DK0945464T3 (OSRAM) |
| ES (2) | ES2156035T3 (OSRAM) |
| GB (2) | GB9601081D0 (OSRAM) |
| GR (2) | GR3033436T3 (OSRAM) |
| PT (2) | PT853661E (OSRAM) |
| WO (1) | WO1997013844A1 (OSRAM) |
Families Citing this family (188)
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| US6025154A (en) | 1995-06-06 | 2000-02-15 | Human Genome Sciences, Inc. | Polynucleotides encoding human G-protein chemokine receptor HDGNR10 |
| US7368111B2 (en) | 1995-10-06 | 2008-05-06 | Cambridge Antibody Technology Limited | Human antibodies specific for TGFβ2 |
| US7888466B2 (en) | 1996-01-11 | 2011-02-15 | Human Genome Sciences, Inc. | Human G-protein chemokine receptor HSATU68 |
| US6673341B2 (en) | 1998-07-06 | 2004-01-06 | Beth Israel Deaconness Medical Center | Methods of inhibiting proliferative diseases by inhibiting TGF-β-mediated angiogenesis |
| WO2000062062A1 (en) * | 1999-04-09 | 2000-10-19 | Hanmi Pharm Co., Ltd. | METHOD FOR QUANTIFYING TRANSFORMING GROWTH FACTOR-β1 AND METHOD FOR DETECTING CANCER BY USING SAME |
| US6492497B1 (en) * | 1999-04-30 | 2002-12-10 | Cambridge Antibody Technology Limited | Specific binding members for TGFbeta1 |
| EP1486560A3 (en) * | 1999-04-30 | 2005-02-09 | Cambridge Antibody Technology LTD | Specific antibodies and antibody fragments for TGFBETA1 |
| US20040001826A1 (en) | 1999-06-30 | 2004-01-01 | Millennium Pharmaceuticals, Inc. | Glycoprotein VI and uses thereof |
| US7291714B1 (en) | 1999-06-30 | 2007-11-06 | Millennium Pharmaceuticals, Inc. | Glycoprotein VI and uses thereof |
| AU7825500A (en) * | 1999-10-07 | 2001-04-23 | Pharmacia Corporation | Inhibition enzyme linked immunosorbent assay (iELISA) for the detection and quantification of antibodies in biological samples |
| SE9903895D0 (sv) * | 1999-10-28 | 1999-10-28 | Active Biotech Ab | Novel compounds |
| MXPA02012434A (es) | 2000-06-16 | 2004-09-06 | Cambridge Antibody Tech | Anticuerpos que se unen inmunoespecificamente a estimulador de linfocitos ii. |
| TWI327600B (en) | 2000-11-28 | 2010-07-21 | Medimmune Llc | Methods of administering/dosing anti-rsv antibodies for prophylaxis and treatment |
| CA2430257A1 (en) * | 2000-11-28 | 2002-06-06 | Amgen, Inc. | Transforming growth factor-beta-related molecules and uses thereof |
| US7175988B2 (en) | 2001-02-09 | 2007-02-13 | Human Genome Sciences, Inc. | Human G-protein Chemokine Receptor (CCR5) HDGNR10 |
| WO2002064612A2 (en) * | 2001-02-09 | 2002-08-22 | Human Genome Sciences, Inc. | Human g-protein chemokine receptor (ccr5) hdgnr10 |
| MXPA03009408A (es) | 2001-04-13 | 2004-01-29 | Human Genome Sciences Inc | Factor de crecimiento endotelial vascular 2. |
| ES2437992T3 (es) | 2001-05-25 | 2014-01-15 | Human Genome Sciences, Inc. | Anticuerpos que se unen inmunoespecíficamente a los receptores de TRAIL |
| US7393934B2 (en) | 2001-12-21 | 2008-07-01 | Human Genome Sciences, Inc. | Human G-protein chemokine receptor (CCR5) HDGNR10 |
| DE10210427A1 (de) | 2002-03-09 | 2003-10-09 | Hans Konrad Mueller-Hermelink | Humaner monoklonaler Antikörper |
| EP2270049A3 (en) | 2002-04-12 | 2011-03-09 | Medimmune, Inc. | Recombinant anti-interleukin-9-antibody |
| EP2070949B1 (en) | 2002-06-10 | 2013-01-16 | Vaccinex, Inc. | C35 antibodies and their use in the treatment of cancer |
| US7425618B2 (en) | 2002-06-14 | 2008-09-16 | Medimmune, Inc. | Stabilized anti-respiratory syncytial virus (RSV) antibody formulations |
| US7772372B2 (en) | 2002-07-04 | 2010-08-10 | Patrys Limited | Neoplasm specific antibodies and uses thereof |
| DK1551876T3 (da) | 2002-10-16 | 2011-06-14 | Purdue Pharma Lp | Antistoffer, der binder til celle-associerede ca 125/0722P og fremgangsmåder til anvendelse deraf |
| GB0224436D0 (en) * | 2002-10-21 | 2002-11-27 | Univ Cambridge Tech | Polypetides methods and means |
| WO2004056875A1 (en) | 2002-12-23 | 2004-07-08 | Wyeth | Antibodies against pd-1 and uses therefor |
| DE10311248A1 (de) | 2003-03-14 | 2004-09-30 | Müller-Hermelink, Hans Konrad, Prof. Dr. | Humaner monoklonaler Antikörper |
| KR101224235B1 (ko) | 2003-04-11 | 2013-01-25 | 메디뮨 엘엘씨 | 재조합 ｉｌ９ 항체 및 그의 용도 |
| EP2390262A1 (en) | 2003-05-16 | 2011-11-30 | Intermune, Inc. | Synthetic chemokine receptor ligands and methods of use thereof |
| WO2005010049A2 (en) * | 2003-07-09 | 2005-02-03 | Eli Lilly And Company | Tgf-beta1 ligands |
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Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU1539188A (en) * | 1987-05-04 | 1988-11-10 | Bristol-Myers Squibb Company | TGF-B2 and novel compositions having anti-neoplastic activity |
| US5571714A (en) * | 1988-12-22 | 1996-11-05 | Celtrix Pharmaceuticals, Inc. | Monoclonal antibodies which bind both transforming growth factors β1 and β2 and methods of use |
| DK0494264T3 (da) * | 1989-09-29 | 1998-01-26 | Jolla Cancer Res Found | Inhibering af transformede vækstfaktor til hindring af akkumulation af ekstracellulær matrix |
| GB9106678D0 (en) * | 1991-03-28 | 1991-05-15 | Ferguson Mark W J | Wound healing |
| EP0940468A1 (en) * | 1991-06-14 | 1999-09-08 | Genentech, Inc. | Humanized antibody variable domain |
| ES2341666T3 (es) * | 1991-12-02 | 2010-06-24 | Medimmune Limited | Produccion de autoanticuerpos de repertorios de segmentos de anticue rpos expresados en la superficie de fagos. |
| AU4111893A (en) * | 1992-04-23 | 1993-11-29 | La Jolla Cancer Research Foundation | Methods for treating vascular disorders by inhibiting the endothelin stimulatory activity of TGFbeta |
| DK0672142T3 (da) * | 1992-12-04 | 2001-06-18 | Medical Res Council | Multivalente og multispecifikke bindingsproteiner samt fremstilling og anvendelse af disse |
| GB2288118A (en) * | 1994-03-29 | 1995-10-11 | Univ Manchester | Wound healing composition |
| NZ282856A (en) * | 1994-03-29 | 1998-06-26 | Univ Manchester | Promoting wound healing using an agent (antibody) specific to a growth factor or associated protein |
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1996
- 1996-01-19 GB GBGB9601081.4A patent/GB9601081D0/en active Pending
- 1996-10-07 EP EP99102166A patent/EP0945464B1/en not_active Expired - Lifetime
- 1996-10-07 JP JP51480997A patent/JP4387458B2/ja not_active Expired - Lifetime
- 1996-10-07 CA CA002233042A patent/CA2233042C/en not_active Expired - Fee Related
- 1996-10-07 DK DK99102166T patent/DK0945464T3/da active
- 1996-10-07 PT PT96932730T patent/PT853661E/pt unknown
- 1996-10-07 ES ES99102166T patent/ES2156035T3/es not_active Expired - Lifetime
- 1996-10-07 AU AU71405/96A patent/AU702049B2/en not_active Ceased
- 1996-10-07 EP EP96932730A patent/EP0853661B1/en not_active Expired - Lifetime
- 1996-10-07 DE DE69607191T patent/DE69607191T2/de not_active Expired - Lifetime
- 1996-10-07 WO PCT/GB1996/002450 patent/WO1997013844A1/en not_active Ceased
- 1996-10-07 PT PT99102166T patent/PT945464E/pt unknown
- 1996-10-07 DE DE69611766T patent/DE69611766T2/de not_active Expired - Lifetime
- 1996-10-07 AT AT99102166T patent/ATE199091T1/de not_active IP Right Cessation
- 1996-10-07 ES ES96932730T patent/ES2146020T3/es not_active Expired - Lifetime
- 1996-10-07 GB GB9620920A patent/GB2305921B/en not_active Expired - Fee Related
- 1996-10-07 CA CA002599488A patent/CA2599488A1/en not_active Abandoned
- 1996-10-07 AT AT96932730T patent/ATE190650T1/de active
- 1996-10-07 DK DK96932730T patent/DK0853661T3/da active
-
2000
- 2000-05-18 GR GR20000401123T patent/GR3033436T3/el unknown
-
2001
- 2001-04-20 GR GR20010400625T patent/GR3035775T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DE69607191T2 (de) | 2000-09-28 |
| DE69607191D1 (de) | 2000-04-20 |
| EP0853661A1 (en) | 1998-07-22 |
| GB9620920D0 (en) | 1996-11-27 |
| GB2305921A (en) | 1997-04-23 |
| JP2000500643A (ja) | 2000-01-25 |
| DK0945464T3 (da) | 2001-05-07 |
| GR3035775T3 (en) | 2001-07-31 |
| AU7140596A (en) | 1997-04-30 |
| WO1997013844A1 (en) | 1997-04-17 |
| GB2305921B (en) | 1999-10-20 |
| GB9601081D0 (en) | 1996-03-20 |
| ES2156035T3 (es) | 2001-06-01 |
| ATE190650T1 (de) | 2000-04-15 |
| EP0945464B1 (en) | 2001-02-07 |
| DE69611766D1 (de) | 2001-03-15 |
| AU702049B2 (en) | 1999-02-11 |
| PT853661E (pt) | 2000-08-31 |
| ATE199091T1 (de) | 2001-02-15 |
| CA2233042C (en) | 2007-12-18 |
| GR3033436T3 (en) | 2000-09-29 |
| DK0853661T3 (da) | 2000-08-14 |
| EP0945464A1 (en) | 1999-09-29 |
| CA2599488A1 (en) | 1997-04-17 |
| PT945464E (pt) | 2001-07-31 |
| EP0853661B1 (en) | 2000-03-15 |
| ES2146020T3 (es) | 2000-07-16 |
| CA2233042A1 (en) | 1997-04-17 |
| JP4387458B2 (ja) | 2009-12-16 |
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