DE69407430T2 - Neues verfahren zur herstellung von (s)-1-[2(s)-(1,3-dihydro-1,3-dioxoisoindol-2-yl)-1-oxo-3-phenylpropyl]-1,2,3,4-tetrahydropyridin-2-carbonsäuremethylester und dessen zwischenprodukte - Google Patents
Neues verfahren zur herstellung von (s)-1-[2(s)-(1,3-dihydro-1,3-dioxoisoindol-2-yl)-1-oxo-3-phenylpropyl]-1,2,3,4-tetrahydropyridin-2-carbonsäuremethylester und dessen zwischenprodukteInfo
- Publication number
- DE69407430T2 DE69407430T2 DE69407430T DE69407430T DE69407430T2 DE 69407430 T2 DE69407430 T2 DE 69407430T2 DE 69407430 T DE69407430 T DE 69407430T DE 69407430 T DE69407430 T DE 69407430T DE 69407430 T2 DE69407430 T2 DE 69407430T2
- Authority
- DE
- Germany
- Prior art keywords
- oxo
- cyclohex
- chloro
- dihydro
- give
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/33—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C211/39—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of an unsaturated carbon skeleton
- C07C211/40—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of an unsaturated carbon skeleton containing only non-condensed rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/12—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups
- C07C233/14—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a ring other than a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15597293A | 1993-11-19 | 1993-11-19 | |
| PCT/US1994/011941 WO1995014663A2 (en) | 1993-11-19 | 1994-10-20 | Novel process for preparing (s)-1-[2(s)-(1,3-dihydro-1,3-dioxo-isoindo-2-yl)-1-oxo-3-phenylpropyl]-1,2,3,4-tetrahydro-2-pyridine-carboxylic acid methyl ester and intermediates thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69407430D1 DE69407430D1 (de) | 1998-01-29 |
| DE69407430T2 true DE69407430T2 (de) | 1998-04-09 |
Family
ID=22557529
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69407430T Expired - Lifetime DE69407430T2 (de) | 1993-11-19 | 1994-10-20 | Neues verfahren zur herstellung von (s)-1-[2(s)-(1,3-dihydro-1,3-dioxoisoindol-2-yl)-1-oxo-3-phenylpropyl]-1,2,3,4-tetrahydropyridin-2-carbonsäuremethylester und dessen zwischenprodukte |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US5502253A (enExample) |
| EP (1) | EP0729456B1 (enExample) |
| JP (1) | JP3547749B2 (enExample) |
| KR (1) | KR100310592B1 (enExample) |
| CN (1) | CN1041627C (enExample) |
| AT (1) | ATE161251T1 (enExample) |
| AU (1) | AU683956B2 (enExample) |
| CA (1) | CA2177044C (enExample) |
| DE (1) | DE69407430T2 (enExample) |
| DK (1) | DK0729456T3 (enExample) |
| ES (1) | ES2112034T3 (enExample) |
| FI (1) | FI962045A0 (enExample) |
| GR (1) | GR3025899T3 (enExample) |
| HU (1) | HU220895B1 (enExample) |
| IL (1) | IL111656A (enExample) |
| NO (1) | NO309269B1 (enExample) |
| NZ (1) | NZ275939A (enExample) |
| TW (1) | TW321638B (enExample) |
| WO (1) | WO1995014663A2 (enExample) |
| ZA (1) | ZA949030B (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8049732B2 (en) * | 2007-01-03 | 2011-11-01 | Apple Inc. | Front-end signal compensation |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4608082A (en) * | 1985-02-19 | 1986-08-26 | Union Carbide Corporation | Herbicidal cycloalkenyl acetamides |
| ZA874107B (enExample) * | 1986-06-13 | 1987-12-09 | ||
| US4973585A (en) * | 1986-06-13 | 1990-11-27 | Merrell Dow Pharmaceuticals | Tricyclic lactams active as antihypertensive agents |
| US4824832A (en) * | 1987-12-30 | 1989-04-25 | Merrell Dow Pharmaceuticals Inc. | Sulfhydryl containing tricyclic lactams and their pharmacological methods of use |
| US5430145A (en) * | 1990-10-18 | 1995-07-04 | Merrell Dow Pharmaceuticals Inc. | Mercaptoacetylamide derivatives useful as inhibitors of enkephalinase and ace |
-
1994
- 1994-10-20 CA CA002177044A patent/CA2177044C/en not_active Expired - Fee Related
- 1994-10-20 HU HU9601335A patent/HU220895B1/hu not_active IP Right Cessation
- 1994-10-20 DK DK95900385.6T patent/DK0729456T3/da active
- 1994-10-20 CN CN94194207A patent/CN1041627C/zh not_active Expired - Fee Related
- 1994-10-20 NZ NZ275939A patent/NZ275939A/en not_active IP Right Cessation
- 1994-10-20 JP JP51506295A patent/JP3547749B2/ja not_active Expired - Fee Related
- 1994-10-20 AU AU81225/94A patent/AU683956B2/en not_active Ceased
- 1994-10-20 DE DE69407430T patent/DE69407430T2/de not_active Expired - Lifetime
- 1994-10-20 ES ES95900385T patent/ES2112034T3/es not_active Expired - Lifetime
- 1994-10-20 AT AT95900385T patent/ATE161251T1/de active
- 1994-10-20 WO PCT/US1994/011941 patent/WO1995014663A2/en not_active Ceased
- 1994-10-20 EP EP95900385A patent/EP0729456B1/en not_active Expired - Lifetime
- 1994-10-20 KR KR1019960702648A patent/KR100310592B1/ko not_active Expired - Fee Related
- 1994-10-20 FI FI962045A patent/FI962045A0/fi unknown
- 1994-11-14 ZA ZA949030A patent/ZA949030B/xx unknown
- 1994-11-15 TW TW083110598A patent/TW321638B/zh not_active IP Right Cessation
- 1994-11-16 IL IL11165694A patent/IL111656A/xx not_active IP Right Cessation
-
1995
- 1995-03-30 US US08/415,028 patent/US5502253A/en not_active Expired - Lifetime
-
1996
- 1996-03-30 US US08/413,649 patent/US5508411A/en not_active Expired - Lifetime
- 1996-05-15 NO NO961999A patent/NO309269B1/no not_active IP Right Cessation
-
1998
- 1998-01-14 GR GR980400072T patent/GR3025899T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HUT74326A (en) | 1996-12-30 |
| CN1135217A (zh) | 1996-11-06 |
| IL111656A0 (en) | 1995-01-24 |
| IL111656A (en) | 1999-06-20 |
| KR100310592B1 (ko) | 2002-05-13 |
| ATE161251T1 (de) | 1998-01-15 |
| NO961999L (no) | 1996-05-15 |
| EP0729456A1 (en) | 1996-09-04 |
| EP0729456B1 (en) | 1997-12-17 |
| HU9601335D0 (en) | 1996-07-29 |
| NZ275939A (en) | 1997-04-24 |
| WO1995014663A2 (en) | 1995-06-01 |
| ES2112034T3 (es) | 1998-03-16 |
| GR3025899T3 (en) | 1998-04-30 |
| DK0729456T3 (da) | 1998-03-30 |
| JPH09505583A (ja) | 1997-06-03 |
| AU683956B2 (en) | 1997-11-27 |
| CA2177044A1 (en) | 1995-06-01 |
| NO309269B1 (no) | 2001-01-08 |
| US5502253A (en) | 1996-03-26 |
| DE69407430D1 (de) | 1998-01-29 |
| WO1995014663A3 (en) | 1995-08-17 |
| AU8122594A (en) | 1995-06-13 |
| ZA949030B (en) | 1995-07-18 |
| JP3547749B2 (ja) | 2004-07-28 |
| FI962045A7 (fi) | 1996-05-14 |
| CA2177044C (en) | 1999-06-01 |
| US5508411A (en) | 1996-04-16 |
| FI962045L (fi) | 1996-05-14 |
| HU220895B1 (en) | 2002-06-29 |
| NO961999D0 (no) | 1996-05-15 |
| FI962045A0 (fi) | 1996-05-14 |
| TW321638B (enExample) | 1997-12-01 |
| CN1041627C (zh) | 1999-01-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |