ZA949030B - Novel process for preparing (S)-1-[2-(S)-(1,3-dihydro 1,3-dioxo-isoindo-2-yl)-1-oxo-3-phenylpropyl]-1,2,3,4-tetrahydro-2-pyridine-carboxylic acid methyl ester and intermediates thereof - Google Patents

Novel process for preparing (S)-1-[2-(S)-(1,3-dihydro 1,3-dioxo-isoindo-2-yl)-1-oxo-3-phenylpropyl]-1,2,3,4-tetrahydro-2-pyridine-carboxylic acid methyl ester and intermediates thereof

Info

Publication number
ZA949030B
ZA949030B ZA949030A ZA949030A ZA949030B ZA 949030 B ZA949030 B ZA 949030B ZA 949030 A ZA949030 A ZA 949030A ZA 949030 A ZA949030 A ZA 949030A ZA 949030 B ZA949030 B ZA 949030B
Authority
ZA
South Africa
Prior art keywords
oxo
phenylpropyl
carboxylic acid
isoindo
dioxo
Prior art date
Application number
ZA949030A
Other languages
English (en)
Inventor
Gary A Flynn
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of ZA949030B publication Critical patent/ZA949030B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00Compounds containing amino groups bound to a carbon skeleton
    • C07C211/33Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C211/39Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of an unsaturated carbon skeleton
    • C07C211/40Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of an unsaturated carbon skeleton containing only non-condensed rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00Carboxylic acid amides
    • C07C233/01Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/12Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups
    • C07C233/14Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a ring other than a six-membered aromatic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
ZA949030A 1993-11-19 1994-11-14 Novel process for preparing (S)-1-[2-(S)-(1,3-dihydro 1,3-dioxo-isoindo-2-yl)-1-oxo-3-phenylpropyl]-1,2,3,4-tetrahydro-2-pyridine-carboxylic acid methyl ester and intermediates thereof ZA949030B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US15597293A 1993-11-19 1993-11-19

Publications (1)

Publication Number Publication Date
ZA949030B true ZA949030B (en) 1995-07-18

Family

ID=22557529

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA949030A ZA949030B (en) 1993-11-19 1994-11-14 Novel process for preparing (S)-1-[2-(S)-(1,3-dihydro 1,3-dioxo-isoindo-2-yl)-1-oxo-3-phenylpropyl]-1,2,3,4-tetrahydro-2-pyridine-carboxylic acid methyl ester and intermediates thereof

Country Status (20)

Country Link
US (2) US5502253A (enExample)
EP (1) EP0729456B1 (enExample)
JP (1) JP3547749B2 (enExample)
KR (1) KR100310592B1 (enExample)
CN (1) CN1041627C (enExample)
AT (1) ATE161251T1 (enExample)
AU (1) AU683956B2 (enExample)
CA (1) CA2177044C (enExample)
DE (1) DE69407430T2 (enExample)
DK (1) DK0729456T3 (enExample)
ES (1) ES2112034T3 (enExample)
FI (1) FI962045A0 (enExample)
GR (1) GR3025899T3 (enExample)
HU (1) HU220895B1 (enExample)
IL (1) IL111656A (enExample)
NO (1) NO309269B1 (enExample)
NZ (1) NZ275939A (enExample)
TW (1) TW321638B (enExample)
WO (1) WO1995014663A2 (enExample)
ZA (1) ZA949030B (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8049732B2 (en) * 2007-01-03 2011-11-01 Apple Inc. Front-end signal compensation

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4608082A (en) * 1985-02-19 1986-08-26 Union Carbide Corporation Herbicidal cycloalkenyl acetamides
ZA874107B (enExample) * 1986-06-13 1987-12-09
US4973585A (en) * 1986-06-13 1990-11-27 Merrell Dow Pharmaceuticals Tricyclic lactams active as antihypertensive agents
US4824832A (en) * 1987-12-30 1989-04-25 Merrell Dow Pharmaceuticals Inc. Sulfhydryl containing tricyclic lactams and their pharmacological methods of use
US5430145A (en) * 1990-10-18 1995-07-04 Merrell Dow Pharmaceuticals Inc. Mercaptoacetylamide derivatives useful as inhibitors of enkephalinase and ace

Also Published As

Publication number Publication date
HUT74326A (en) 1996-12-30
CN1135217A (zh) 1996-11-06
IL111656A0 (en) 1995-01-24
IL111656A (en) 1999-06-20
KR100310592B1 (ko) 2002-05-13
ATE161251T1 (de) 1998-01-15
NO961999L (no) 1996-05-15
EP0729456A1 (en) 1996-09-04
EP0729456B1 (en) 1997-12-17
HU9601335D0 (en) 1996-07-29
NZ275939A (en) 1997-04-24
WO1995014663A2 (en) 1995-06-01
ES2112034T3 (es) 1998-03-16
GR3025899T3 (en) 1998-04-30
DK0729456T3 (da) 1998-03-30
JPH09505583A (ja) 1997-06-03
AU683956B2 (en) 1997-11-27
CA2177044A1 (en) 1995-06-01
NO309269B1 (no) 2001-01-08
US5502253A (en) 1996-03-26
DE69407430D1 (de) 1998-01-29
WO1995014663A3 (en) 1995-08-17
AU8122594A (en) 1995-06-13
JP3547749B2 (ja) 2004-07-28
FI962045A7 (fi) 1996-05-14
CA2177044C (en) 1999-06-01
US5508411A (en) 1996-04-16
FI962045L (fi) 1996-05-14
HU220895B1 (en) 2002-06-29
NO961999D0 (no) 1996-05-15
DE69407430T2 (de) 1998-04-09
FI962045A0 (fi) 1996-05-14
TW321638B (enExample) 1997-12-01
CN1041627C (zh) 1999-01-13

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