HU220895B1 - Process for preparing (s)-1-[2(s)-(1,3-dihydro-1,3-dioxo-isoindol-2-yl)-1-oxo-3-phenylpropyl]-1,2,3,4-tetrahydro-2-pyridine-carboxylic acid methyl ester and intermediates thereof - Google Patents
Process for preparing (s)-1-[2(s)-(1,3-dihydro-1,3-dioxo-isoindol-2-yl)-1-oxo-3-phenylpropyl]-1,2,3,4-tetrahydro-2-pyridine-carboxylic acid methyl ester and intermediates thereof Download PDFInfo
- Publication number
- HU220895B1 HU220895B1 HU9601335A HU9601335A HU220895B1 HU 220895 B1 HU220895 B1 HU 220895B1 HU 9601335 A HU9601335 A HU 9601335A HU 9601335 A HU9601335 A HU 9601335A HU 220895 B1 HU220895 B1 HU 220895B1
- Authority
- HU
- Hungary
- Prior art keywords
- cyclohex
- chloro
- oxo
- dihydro
- enyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/33—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C211/39—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of an unsaturated carbon skeleton
- C07C211/40—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of an unsaturated carbon skeleton containing only non-condensed rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/12—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups
- C07C233/14—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a ring other than a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15597293A | 1993-11-19 | 1993-11-19 | |
| PCT/US1994/011941 WO1995014663A2 (en) | 1993-11-19 | 1994-10-20 | Novel process for preparing (s)-1-[2(s)-(1,3-dihydro-1,3-dioxo-isoindo-2-yl)-1-oxo-3-phenylpropyl]-1,2,3,4-tetrahydro-2-pyridine-carboxylic acid methyl ester and intermediates thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| HU9601335D0 HU9601335D0 (en) | 1996-07-29 |
| HUT74326A HUT74326A (en) | 1996-12-30 |
| HU220895B1 true HU220895B1 (en) | 2002-06-29 |
Family
ID=22557529
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU9601335A HU220895B1 (en) | 1993-11-19 | 1994-10-20 | Process for preparing (s)-1-[2(s)-(1,3-dihydro-1,3-dioxo-isoindol-2-yl)-1-oxo-3-phenylpropyl]-1,2,3,4-tetrahydro-2-pyridine-carboxylic acid methyl ester and intermediates thereof |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US5502253A (enExample) |
| EP (1) | EP0729456B1 (enExample) |
| JP (1) | JP3547749B2 (enExample) |
| KR (1) | KR100310592B1 (enExample) |
| CN (1) | CN1041627C (enExample) |
| AT (1) | ATE161251T1 (enExample) |
| AU (1) | AU683956B2 (enExample) |
| CA (1) | CA2177044C (enExample) |
| DE (1) | DE69407430T2 (enExample) |
| DK (1) | DK0729456T3 (enExample) |
| ES (1) | ES2112034T3 (enExample) |
| FI (1) | FI962045L (enExample) |
| GR (1) | GR3025899T3 (enExample) |
| HU (1) | HU220895B1 (enExample) |
| IL (1) | IL111656A (enExample) |
| NO (1) | NO309269B1 (enExample) |
| NZ (1) | NZ275939A (enExample) |
| TW (1) | TW321638B (enExample) |
| WO (1) | WO1995014663A2 (enExample) |
| ZA (1) | ZA949030B (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8049732B2 (en) * | 2007-01-03 | 2011-11-01 | Apple Inc. | Front-end signal compensation |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4608082A (en) * | 1985-02-19 | 1986-08-26 | Union Carbide Corporation | Herbicidal cycloalkenyl acetamides |
| US4973585A (en) * | 1986-06-13 | 1990-11-27 | Merrell Dow Pharmaceuticals | Tricyclic lactams active as antihypertensive agents |
| CA1337654C (en) * | 1986-06-13 | 1995-11-28 | Gary A. Flynn | Fused tricyclic lactams as antihypertensive agents |
| US4824832A (en) * | 1987-12-30 | 1989-04-25 | Merrell Dow Pharmaceuticals Inc. | Sulfhydryl containing tricyclic lactams and their pharmacological methods of use |
| US5430145A (en) * | 1990-10-18 | 1995-07-04 | Merrell Dow Pharmaceuticals Inc. | Mercaptoacetylamide derivatives useful as inhibitors of enkephalinase and ace |
-
1994
- 1994-10-20 CN CN94194207A patent/CN1041627C/zh not_active Expired - Fee Related
- 1994-10-20 CA CA002177044A patent/CA2177044C/en not_active Expired - Fee Related
- 1994-10-20 NZ NZ275939A patent/NZ275939A/en not_active IP Right Cessation
- 1994-10-20 HU HU9601335A patent/HU220895B1/hu not_active IP Right Cessation
- 1994-10-20 WO PCT/US1994/011941 patent/WO1995014663A2/en not_active Ceased
- 1994-10-20 AT AT95900385T patent/ATE161251T1/de active
- 1994-10-20 DE DE69407430T patent/DE69407430T2/de not_active Expired - Lifetime
- 1994-10-20 AU AU81225/94A patent/AU683956B2/en not_active Ceased
- 1994-10-20 KR KR1019960702648A patent/KR100310592B1/ko not_active Expired - Fee Related
- 1994-10-20 ES ES95900385T patent/ES2112034T3/es not_active Expired - Lifetime
- 1994-10-20 FI FI962045A patent/FI962045L/fi unknown
- 1994-10-20 DK DK95900385.6T patent/DK0729456T3/da active
- 1994-10-20 EP EP95900385A patent/EP0729456B1/en not_active Expired - Lifetime
- 1994-10-20 JP JP51506295A patent/JP3547749B2/ja not_active Expired - Fee Related
- 1994-11-14 ZA ZA949030A patent/ZA949030B/xx unknown
- 1994-11-15 TW TW083110598A patent/TW321638B/zh not_active IP Right Cessation
- 1994-11-16 IL IL11165694A patent/IL111656A/xx not_active IP Right Cessation
-
1995
- 1995-03-30 US US08/415,028 patent/US5502253A/en not_active Expired - Lifetime
-
1996
- 1996-03-30 US US08/413,649 patent/US5508411A/en not_active Expired - Lifetime
- 1996-05-15 NO NO961999A patent/NO309269B1/no not_active IP Right Cessation
-
1998
- 1998-01-14 GR GR980400072T patent/GR3025899T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2177044C (en) | 1999-06-01 |
| HU9601335D0 (en) | 1996-07-29 |
| TW321638B (enExample) | 1997-12-01 |
| NO961999L (no) | 1996-05-15 |
| GR3025899T3 (en) | 1998-04-30 |
| WO1995014663A3 (en) | 1995-08-17 |
| EP0729456A1 (en) | 1996-09-04 |
| FI962045A7 (fi) | 1996-05-14 |
| DK0729456T3 (da) | 1998-03-30 |
| ES2112034T3 (es) | 1998-03-16 |
| FI962045A0 (fi) | 1996-05-14 |
| CN1135217A (zh) | 1996-11-06 |
| IL111656A (en) | 1999-06-20 |
| FI962045L (fi) | 1996-05-14 |
| CA2177044A1 (en) | 1995-06-01 |
| EP0729456B1 (en) | 1997-12-17 |
| US5502253A (en) | 1996-03-26 |
| JP3547749B2 (ja) | 2004-07-28 |
| NO961999D0 (no) | 1996-05-15 |
| HUT74326A (en) | 1996-12-30 |
| DE69407430T2 (de) | 1998-04-09 |
| US5508411A (en) | 1996-04-16 |
| DE69407430D1 (de) | 1998-01-29 |
| JPH09505583A (ja) | 1997-06-03 |
| ATE161251T1 (de) | 1998-01-15 |
| AU683956B2 (en) | 1997-11-27 |
| KR100310592B1 (ko) | 2002-05-13 |
| IL111656A0 (en) | 1995-01-24 |
| ZA949030B (en) | 1995-07-18 |
| AU8122594A (en) | 1995-06-13 |
| CN1041627C (zh) | 1999-01-13 |
| WO1995014663A2 (en) | 1995-06-01 |
| NZ275939A (en) | 1997-04-24 |
| NO309269B1 (no) | 2001-01-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GB9A | Succession in title |
Owner name: AVENTIS INC., US Free format text: FORMER OWNER(S): MERRELL PHARMACEUTICAL INC., US |
|
| FH91 | Appointment of a representative |
Free format text: FORMER REPRESENTATIVE(S): SOMLAI MARIA, S.B.G. & K. BUDAPESTI NEMZETKOEZI SZABADALMI IRODA, HU Representative=s name: DANUBIA SZABADALMI ES JOGI IRODA KFT., HU |
|
| FH92 | Termination of representative |
Representative=s name: SOMLAI MARIA, S.B.G. & K. BUDAPESTI NEMZETKOEZ, HU |
|
| HC9A | Change of name, address |
Owner name: AVENTIS INC., US Free format text: FORMER OWNER(S): MERRELL PHARMACEUTICAL INC., US; AVENTIS INC., US |
|
| MM4A | Lapse of definitive patent protection due to non-payment of fees |