NZ275939A - Preparation of (s)-1-[2(s)-(1,3-dihydro-1,3-dioxoisoindol-2-yl)-1-oxo-3-phenylpropyl ]-1,2,3,4-tetrahydropyridine-2-carboxylic acid methyl ester - Google Patents

Preparation of (s)-1-[2(s)-(1,3-dihydro-1,3-dioxoisoindol-2-yl)-1-oxo-3-phenylpropyl ]-1,2,3,4-tetrahydropyridine-2-carboxylic acid methyl ester

Info

Publication number
NZ275939A
NZ275939A NZ275939A NZ27593994A NZ275939A NZ 275939 A NZ275939 A NZ 275939A NZ 275939 A NZ275939 A NZ 275939A NZ 27593994 A NZ27593994 A NZ 27593994A NZ 275939 A NZ275939 A NZ 275939A
Authority
NZ
New Zealand
Prior art keywords
cyclohex
oxo
chloro
give
dihydro
Prior art date
Application number
NZ275939A
Other languages
English (en)
Inventor
Gary Alan Flynn
Original Assignee
Merrell Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Pharma Inc filed Critical Merrell Pharma Inc
Publication of NZ275939A publication Critical patent/NZ275939A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00Compounds containing amino groups bound to a carbon skeleton
    • C07C211/33Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C211/39Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of an unsaturated carbon skeleton
    • C07C211/40Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of an unsaturated carbon skeleton containing only non-condensed rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00Carboxylic acid amides
    • C07C233/01Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/12Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups
    • C07C233/14Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a ring other than a six-membered aromatic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
NZ275939A 1993-11-19 1994-10-20 Preparation of (s)-1-[2(s)-(1,3-dihydro-1,3-dioxoisoindol-2-yl)-1-oxo-3-phenylpropyl ]-1,2,3,4-tetrahydropyridine-2-carboxylic acid methyl ester NZ275939A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US15597293A 1993-11-19 1993-11-19

Publications (1)

Publication Number Publication Date
NZ275939A true NZ275939A (en) 1997-04-24

Family

ID=22557529

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ275939A NZ275939A (en) 1993-11-19 1994-10-20 Preparation of (s)-1-[2(s)-(1,3-dihydro-1,3-dioxoisoindol-2-yl)-1-oxo-3-phenylpropyl ]-1,2,3,4-tetrahydropyridine-2-carboxylic acid methyl ester

Country Status (20)

Country Link
US (2) US5502253A (enExample)
EP (1) EP0729456B1 (enExample)
JP (1) JP3547749B2 (enExample)
KR (1) KR100310592B1 (enExample)
CN (1) CN1041627C (enExample)
AT (1) ATE161251T1 (enExample)
AU (1) AU683956B2 (enExample)
CA (1) CA2177044C (enExample)
DE (1) DE69407430T2 (enExample)
DK (1) DK0729456T3 (enExample)
ES (1) ES2112034T3 (enExample)
FI (1) FI962045A0 (enExample)
GR (1) GR3025899T3 (enExample)
HU (1) HU220895B1 (enExample)
IL (1) IL111656A (enExample)
NO (1) NO309269B1 (enExample)
NZ (1) NZ275939A (enExample)
TW (1) TW321638B (enExample)
WO (1) WO1995014663A2 (enExample)
ZA (1) ZA949030B (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8049732B2 (en) * 2007-01-03 2011-11-01 Apple Inc. Front-end signal compensation

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4608082A (en) * 1985-02-19 1986-08-26 Union Carbide Corporation Herbicidal cycloalkenyl acetamides
ZA874107B (enExample) * 1986-06-13 1987-12-09
US4973585A (en) * 1986-06-13 1990-11-27 Merrell Dow Pharmaceuticals Tricyclic lactams active as antihypertensive agents
US4824832A (en) * 1987-12-30 1989-04-25 Merrell Dow Pharmaceuticals Inc. Sulfhydryl containing tricyclic lactams and their pharmacological methods of use
US5430145A (en) * 1990-10-18 1995-07-04 Merrell Dow Pharmaceuticals Inc. Mercaptoacetylamide derivatives useful as inhibitors of enkephalinase and ace

Also Published As

Publication number Publication date
HUT74326A (en) 1996-12-30
CN1135217A (zh) 1996-11-06
IL111656A0 (en) 1995-01-24
IL111656A (en) 1999-06-20
KR100310592B1 (ko) 2002-05-13
ATE161251T1 (de) 1998-01-15
NO961999L (no) 1996-05-15
EP0729456A1 (en) 1996-09-04
EP0729456B1 (en) 1997-12-17
HU9601335D0 (en) 1996-07-29
WO1995014663A2 (en) 1995-06-01
ES2112034T3 (es) 1998-03-16
GR3025899T3 (en) 1998-04-30
DK0729456T3 (da) 1998-03-30
JPH09505583A (ja) 1997-06-03
AU683956B2 (en) 1997-11-27
CA2177044A1 (en) 1995-06-01
NO309269B1 (no) 2001-01-08
US5502253A (en) 1996-03-26
DE69407430D1 (de) 1998-01-29
WO1995014663A3 (en) 1995-08-17
AU8122594A (en) 1995-06-13
ZA949030B (en) 1995-07-18
JP3547749B2 (ja) 2004-07-28
FI962045A7 (fi) 1996-05-14
CA2177044C (en) 1999-06-01
US5508411A (en) 1996-04-16
FI962045L (fi) 1996-05-14
HU220895B1 (en) 2002-06-29
NO961999D0 (no) 1996-05-15
DE69407430T2 (de) 1998-04-09
FI962045A0 (fi) 1996-05-14
TW321638B (enExample) 1997-12-01
CN1041627C (zh) 1999-01-13

Similar Documents

Publication Publication Date Title
FI83312C (fi) Foerfarande foer framstaellning av terapeutiskt aktiva 7-(1-pyrrolidinyl)-1-cyklopropyl-6,8-difluor-1,4 -dihydro-4-oxo-3-kinolinkarboxylsyror och deras salter.
HUT64520A (en) Process forf producing of derivatives of 1,2-dihydro-2-oxopyridine and pharamceutical compositions containing them
WO2017100601A1 (en) Aza-benzimidazole inhibitors of pad4
NO163487B (no) Analogifremgangsmaate for fremstilling av terapeutisk virksomme 1,5-benzoksazepiner.
FI85482C (fi) Foerfarande foer framstaellning av nya terapeutiskt aktiva 9-/3-(4-guanidinofenyl) propylamino/oktahydro-10 oxo-6h-pyridazo/1,2-a//1,2/diazepin-1-karboxylsyraderivat.
KR100459745B1 (ko) 에난티오머적으로순수한이미다졸릴화합물의제조방법
US20210246115A1 (en) Anti-infective heterocyclic compounds and uses thereof
NO172935B (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive amid-derivater
NZ275939A (en) Preparation of (s)-1-[2(s)-(1,3-dihydro-1,3-dioxoisoindol-2-yl)-1-oxo-3-phenylpropyl ]-1,2,3,4-tetrahydropyridine-2-carboxylic acid methyl ester
US7332485B2 (en) Peptide deformylase inhibitors
EP1370258B1 (en) Peptide deformylase inhibitors
US7973173B2 (en) Process for the synthesis of an ACE inhibitor
EP0812838A1 (en) Pyridonecarboxylic acid derivative substituted by bicyclic amino group, ester thereof, salt thereof, and bicyclic amine as intermediate therefor
DE3787160T2 (de) Delta-hydroxy-beta-lysin-Derivate und ihre Produktion.
CN113185505A (zh) 一种喹诺酮基噁唑烷酮类化合物及其制备方法和用途
SK13592001A3 (sk) Syntéza 3-amino-3-arylpropanoátov
EP1399416B1 (en) Peptide deformylase inhibitors
TW201226375A (en) Organic compounds
US6897233B2 (en) Peptide deformylase inhibitors
HU208425B (en) Process for producing anellated azepinone and azocinone derivatives
JP2005532358A (ja) ペプチドデホルミラーゼ阻害剤
US7456211B2 (en) Peptide deformylase inhibitors
EP4104902A1 (en) Compound and drug containing same
NO310025B1 (no) Ny fremgangsmåte for fremstilling av mellomprodukter for inhibitorer av enkefalinase og angiotensinomdannende enzym, og mellomprodukter derav
EP2161269A1 (en) Process for the preparation of amorphous gemifloxacin

Legal Events

Date Code Title Description
RENW Renewal (renewal fees accepted)
RENW Renewal (renewal fees accepted)
RENW Renewal (renewal fees accepted)
EXPY Patent expired