DE69309701T2 - Zusammensetzungen mit verzögerter wirkstoffabgabe zur behandlung periodontaler erkrankungen - Google Patents

Zusammensetzungen mit verzögerter wirkstoffabgabe zur behandlung periodontaler erkrankungen

Info

Publication number
DE69309701T2
DE69309701T2 DE69309701T DE69309701T DE69309701T2 DE 69309701 T2 DE69309701 T2 DE 69309701T2 DE 69309701 T DE69309701 T DE 69309701T DE 69309701 T DE69309701 T DE 69309701T DE 69309701 T2 DE69309701 T2 DE 69309701T2
Authority
DE
Germany
Prior art keywords
compositions
treatment
active substances
periodontal diseases
delayed delivery
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69309701T
Other languages
English (en)
Other versions
DE69309701T3 (de
DE69309701D1 (de
Inventor
Nalinkant Damani
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Procter and Gamble Co
Original Assignee
Procter and Gamble Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25503394&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69309701(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Procter and Gamble Co filed Critical Procter and Gamble Co
Application granted granted Critical
Publication of DE69309701D1 publication Critical patent/DE69309701D1/de
Publication of DE69309701T2 publication Critical patent/DE69309701T2/de
Publication of DE69309701T3 publication Critical patent/DE69309701T3/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0063—Periodont
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/65—Tetracyclines

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cosmetics (AREA)
DE69309701T 1992-10-13 1993-09-22 Zusammensetzungen mit verzögerter wirkstoffabgabe zur behandlung periodontaler erkrankungen Expired - Fee Related DE69309701T3 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US960614 1992-10-13
US07/960,614 US5242910A (en) 1992-10-13 1992-10-13 Sustained release compositions for treating periodontal disease
PCT/US1993/008890 WO1994008562A1 (en) 1992-10-13 1993-09-22 Sustained release compositions for treating periodontal disease

Publications (3)

Publication Number Publication Date
DE69309701D1 DE69309701D1 (de) 1997-05-15
DE69309701T2 true DE69309701T2 (de) 1997-10-30
DE69309701T3 DE69309701T3 (de) 2005-03-24

Family

ID=25503394

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69309701T Expired - Fee Related DE69309701T3 (de) 1992-10-13 1993-09-22 Zusammensetzungen mit verzögerter wirkstoffabgabe zur behandlung periodontaler erkrankungen

Country Status (8)

Country Link
US (1) US5242910A (de)
EP (1) EP0664696B2 (de)
JP (1) JPH08502289A (de)
AT (1) ATE151282T1 (de)
DE (1) DE69309701T3 (de)
ES (1) ES2099977T5 (de)
RU (1) RU95109905A (de)
WO (1) WO1994008562A1 (de)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8851084B2 (en) 2011-07-19 2014-10-07 British American Tobacco (Investments) Limited Cellulose acetate compositions
US9241512B2 (en) 2011-06-23 2016-01-26 British American Tobacco (Investments) Limited Filter material comprising polylactide fibres

Families Citing this family (85)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5575652A (en) * 1987-01-30 1996-11-19 Colgate Palmolive Company Process for applying antibacterial oral composition to dental implant areas
US5447725A (en) * 1993-06-11 1995-09-05 The Procter & Gamble Company Methods for aiding periodontal tissue regeneration
US5616315A (en) * 1994-10-13 1997-04-01 Gillette Canada Inc. Particles including degradable material and anti-microbial agent
US5980945A (en) * 1996-01-16 1999-11-09 Societe De Conseils De Recherches Et D'applications Scientifique S.A. Sustained release drug formulations
US20020111603A1 (en) * 1996-12-02 2002-08-15 Societe De Conseils De Recherches Et D'application Device for local administration of solid or semi-solid formulations and delayed-release formulations for proposal parental administration and preparation process
ES2158611T3 (es) * 1996-12-20 2001-09-01 Alza Corp Composicion en gel inyectable con efecto retard y procedimiento para la preparacion de dicha composicion.
US5885553A (en) * 1997-01-10 1999-03-23 The Procter & Gamble Company Hydrophobic agents for use in oral care products
US5939080A (en) * 1997-01-10 1999-08-17 The Procter & Gamble Company Hydrophobic agents and non-polymeric surfactants use in oral care products
US5885554A (en) * 1997-01-10 1999-03-23 The Procter & Gamble Company Hydrophobic agents and polymeric surfactants
EP1033127A4 (de) 1997-03-18 2006-07-26 Sunstar Inc Zusammensetzungen zur bildung von festkörperpartikeln
US6245345B1 (en) 1998-07-07 2001-06-12 Atrix Laboratories, Inc. Filamentous porous films and methods for producing the same
AU6240099A (en) 1998-08-24 2000-03-14 Susan E Draheim Methods and compositions for treating periodontal disease with an inhibitor of secretory phospholipase A2
EP1000616A1 (de) * 1998-09-25 2000-05-17 Mathias Jozef Maria Schaeken Vorbeugung und Behandlung der Parondotitis
EP1949890A3 (de) 1999-06-04 2011-05-18 ALZA Corporation Implantierbare Gelzusammensetzungen und Herstellungsverfahren dafür
JP2003501375A (ja) * 1999-06-04 2003-01-14 アルザ・コーポレーション 移植可能なゲル組成物および製造方法
US20030211974A1 (en) * 2000-03-21 2003-11-13 Brodbeck Kevin J. Gel composition and methods
DK1274459T3 (da) 2000-04-19 2006-02-06 Genentech Inc Præparater med vedholdende frigivelse indeholdende væksthormon
US8283135B2 (en) 2000-06-30 2012-10-09 The Procter & Gamble Company Oral care compositions containing combinations of anti-bacterial and host-response modulating agents
CA2439120C (en) * 2001-02-23 2011-07-05 Genentech, Inc. Erodible polymers for injection
US7318931B2 (en) * 2001-06-21 2008-01-15 Genentech, Inc. Sustained release formulation
US7829109B2 (en) * 2001-11-14 2010-11-09 Durect Corporation Catheter injectable depot compositions and uses thereof
US6790867B2 (en) * 2002-05-20 2004-09-14 Schering-Plough Animal Health Corporation Compositions and method for treating infection in cattle and swine
US20040001889A1 (en) 2002-06-25 2004-01-01 Guohua Chen Short duration depot formulations
AR039729A1 (es) 2002-06-25 2005-03-09 Alza Corp Formulaciones de deposito de corta duracion
MXPA05001242A (es) 2002-07-31 2005-06-08 Alza Corp Composiciones de deposito inyectable y usos de las mismas.
ES2321505T3 (es) 2002-07-31 2009-06-08 Alza Corporation Composiciones de deposito de polimero multimodal inyectables y empleo de las mismas.
CA2502734A1 (en) * 2002-08-29 2004-03-11 Toray Industries, Inc. Medicinal composition for periodontal pocket administration containing bisphosphonic acid derivative or its salt as the active ingredient
RU2355385C2 (ru) * 2002-11-06 2009-05-20 Алза Корпорейшн Композиции пролонгированного действия с контролируемым высвобождением
US20040136926A1 (en) * 2002-11-08 2004-07-15 Periathamby Antony Raj Intra-oral drug delivery system
NZ540767A (en) 2002-11-27 2009-03-31 Dmi Biosciences Inc Treatment of diseases and conditions mediated by increased phosphorylation
DE10259579B4 (de) * 2002-12-19 2005-07-14 Streubel, Klaus Vorrichtung zum Entfernen von Zahnbelägen
US20040185009A1 (en) * 2003-03-19 2004-09-23 Dexcel Pharma Technologies Ltd. Composition and device for treating periodontal diseases
US20070184084A1 (en) * 2003-05-30 2007-08-09 Guohua Chen Implantable elastomeric caprolactone depot compositions and uses thereof
MXPA05013003A (es) * 2003-05-30 2006-03-17 Alza Corp Composiciones de deposito elastomerico implantables, usos de las mismas y metodo para elaboracion.
JP2007506767A (ja) * 2003-09-25 2007-03-22 ディーエムアイ バイオサイエンシズ インコーポレイテッド Ｎ−アシル−ｌ−アスパラギン酸を利用した方法および製造物
US20050084551A1 (en) 2003-09-26 2005-04-21 Jensen Claude J. Morinda citrifolia-based oral care compositions and methods
US20050281879A1 (en) * 2003-11-14 2005-12-22 Guohua Chen Excipients in drug delivery vehicles
US20050118206A1 (en) * 2003-11-14 2005-06-02 Luk Andrew S. Surfactant-based gel as an injectable, sustained drug delivery vehicle
CA2545809A1 (en) * 2003-11-14 2005-06-02 Alza Corporation Package for pharmaceutical formulation
US20050106214A1 (en) * 2003-11-14 2005-05-19 Guohua Chen Excipients in drug delivery vehicles
JP4792032B2 (ja) 2004-08-13 2011-10-12 シェーリング−プラウ・リミテッド 抗生物質、トリアゾールおよびコルチコステロイドを含む薬学的処方物
ES2747926T3 (es) * 2004-09-27 2020-03-12 Special Water Patents B V Métodos y composiciones para el tratamiento de agua
KR20070083941A (ko) * 2004-10-04 2007-08-24 큐엘티 유에스에이, 인코포레이티드 중합체 전달 조성을 갖는 눈 전달
WO2006112443A1 (ja) * 2005-04-15 2006-10-26 Shinshu University トリアセチンの新規な利用方法及び超音波診断の検査補助剤
WO2007002041A2 (en) * 2005-06-21 2007-01-04 Foster Corporation Drug-filled polymer films
US20090104242A1 (en) * 2005-07-28 2009-04-23 Indiana University Research & Technology Corporati Niobium oxide compositions, nanostructures, bioactive forms and uses thereof
EP3871693A1 (de) 2005-09-27 2021-09-01 Special Water Patents B.V. Zusammensetzungen zur mundpflege
AU2007207618B2 (en) * 2006-01-18 2011-03-24 Foresee Pharmaceuticals Co., Ltd. Pharmaceutical compositions with enhanced stability
WO2007089894A2 (en) * 2006-01-31 2007-08-09 Indiana University Research & Technology Corporation Materials and methods for manufacturing amorphous tricalcium phosphate and metal oxide alloys of amorphous tricalcium phosphate and methods of using the same
JP2010505821A (ja) * 2006-10-05 2010-02-25 パナセア バイオテック リミテッド デポ型注射剤組成物とその調製方法
AU2007320841B2 (en) 2006-11-13 2013-05-02 The Procter & Gamble Company Products and methods for disclosing conditions in the oral cavity
US8298516B2 (en) * 2006-12-22 2012-10-30 Douglas Anderson Calculus dissolving dental composition and methods for using same
US20090181068A1 (en) * 2008-01-14 2009-07-16 Dunn Richard L Low Viscosity Liquid Polymeric Delivery System
WO2009134783A1 (en) * 2008-05-02 2009-11-05 The Procter & Gamble Company Products and methods for disclosing conditions in the oral cavity
US8211406B2 (en) 2008-11-25 2012-07-03 The Procter & Gamble Company Oral care compositions with fused silica
US20120065221A1 (en) 2009-02-26 2012-03-15 Theraquest Biosciences, Inc. Extended Release Oral Pharmaceutical Compositions of 3-Hydroxy-N-Methylmorphinan and Method of Use
MY162904A (en) 2009-04-01 2017-07-31 Colgate Palmolive Co Dentifrice compositions and methods for treating and preventing damage to tooth surfaces
US20110104080A1 (en) 2009-11-03 2011-05-05 David Salloum Salloum Oral Compositions for Treatment of Dry Mouth
US20110104081A1 (en) 2009-11-03 2011-05-05 Douglas Craig Scott Oral Compositions for Treatment of Dry Mouth
AU2011235154B2 (en) 2010-04-01 2014-06-05 The Procter & Gamble Company Whole mouth malodor control by a combination of antibacterial and deodorizing agents
CN103153272A (zh) 2010-07-19 2013-06-12 宝洁公司 包含精油化合物的衍生物的组合物以及在个人护理产品中的用途
US8900557B2 (en) 2010-12-30 2014-12-02 Jr Chem, Llc Dental cleaning composition
US20130344120A1 (en) 2012-06-21 2013-12-26 Douglas Craig Scott Mouth Rinse Emulsions
US10123953B2 (en) 2012-06-21 2018-11-13 The Procter & Gamble Company Reduction of tooth staining derived from cationic antimicrobials
RU2608129C2 (ru) 2012-11-05 2017-01-13 Дзе Проктер Энд Гэмбл Компани Термически обработанная осажденная двуокись кремния
WO2014169109A1 (en) 2013-04-10 2014-10-16 The Procter & Gamble Company Oral care compositions containing polyorganosilsesquioxane particles
CN105102071A (zh) 2013-04-10 2015-11-25 宝洁公司 包含聚有机倍半硅氧烷颗粒的口腔护理组合物
BR112015024772A2 (pt) 2013-04-10 2017-07-18 Procter & Gamble composições para tratamento bucal contendo partículas de poli-organossilsesquioxano
JP6564369B2 (ja) 2013-12-09 2019-08-21 デュレクト コーポレイション 薬学的活性剤複合体、ポリマー複合体、ならびにこれらを伴う組成物及び方法
US20160106804A1 (en) 2014-10-15 2016-04-21 Yuhua Li Pharmaceutical composition with improved stability
JP6833809B2 (ja) 2015-08-04 2021-02-24 アイエスピー インヴェストメンツ エルエルシー アミノ官能性ビニルアルコールエーテルから誘導されたポリマー、およびその用途
US10517808B2 (en) 2015-12-15 2019-12-31 Tartarend, Llc Oral care formulation and method for the removal of tartar and plaque from teeth
US10682340B2 (en) 2016-06-30 2020-06-16 Durect Corporation Depot formulations
EP3478285A4 (de) 2016-06-30 2020-07-22 Durect Corporation Depotformulierungen
EA201990127A1 (ru) 2016-12-30 2020-08-18 Дьюрект Корпорейшн Депо-препарат
US11389383B2 (en) 2017-12-20 2022-07-19 Firmenich Sa Oral care compositions
US11801209B2 (en) 2017-12-21 2023-10-31 Firmenich Sa Cooling and flavor boosting compositions
US10799289B2 (en) 2018-10-15 2020-10-13 Avent, Inc. Compositions, systems, kits, and methods for neural ablation
US11191709B2 (en) 2019-04-26 2021-12-07 The Procter & Gamble Company Reduction of tooth staining derived from cationic antimicrobials
WO2021102896A1 (en) 2019-11-29 2021-06-03 Givaudan Sa Organic compounds
CA3167217A1 (en) 2020-01-13 2021-07-22 Durect Corporation Sustained release drug delivery systems with reduced impurities and related methods
WO2021174475A1 (en) 2020-03-05 2021-09-10 Givaudan Sa Organic compounds
GB202012170D0 (en) 2020-08-05 2020-09-16 Givaudan Sa Organic compounds
WO2022170519A1 (en) 2021-02-09 2022-08-18 Givaudan Sa Organic compounds
GB202105661D0 (en) 2021-04-21 2021-06-02 Givaudan Sa Organic compounds

Family Cites Families (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3498957A (en) * 1965-09-14 1970-03-03 Ethicon Inc Polymerization of cyclic carboxylic esters in the presense of a nonpolymerizable ester plasticizer
BE758156R (fr) * 1970-05-13 1971-04-28 Ethicon Inc Element de suture absorbable et sa
US4017615A (en) * 1970-10-29 1977-04-12 Syntex Corporation Propylene carbonate ointment vehicle
US3736646A (en) * 1971-10-18 1973-06-05 American Cyanamid Co Method of attaching surgical needles to multifilament polyglycolic acid absorbable sutures
US3867190A (en) * 1971-10-18 1975-02-18 American Cyanamid Co Reducing capillarity of polyglycolic acid sutures
US3978203A (en) * 1974-07-12 1976-08-31 Dynatech Corporation Sustained release of pharmaceuticals from polyester matrices
DE2657370C2 (de) * 1976-12-17 1982-11-11 Hans Dr.med. Dr.med.dent. 8000 München Scheicher Mittel zum Bedecken und/oder Ausfüllen von Knochendefekten
US4474750A (en) * 1976-12-27 1984-10-02 Colgate-Palmolive Company Anticalculus oral composition
US4328204A (en) * 1977-03-02 1982-05-04 Ethicon, Inc. Absorbable polymer-drug compounds and method for making same
US4137921A (en) * 1977-06-24 1979-02-06 Ethicon, Inc. Addition copolymers of lactide and glycolide and method of preparation
US4454110A (en) * 1982-05-24 1984-06-12 Forsyth Dental Infirmary For Children Self-gelling liquid composition for topical application in the oral cavity
US4443430A (en) * 1982-11-16 1984-04-17 Ethicon, Inc. Synthetic absorbable hemostatic agent
JPS59222406A (ja) * 1983-06-01 1984-12-14 Teijin Ltd 歯周疾患治療用製剤及びその製造法
US4685883A (en) * 1983-09-12 1987-08-11 Jernberg Gary R Local delivery of chemotherapeutic agents for the treatment of periodontal disease
GR80494B (en) * 1983-10-07 1985-02-04 Forsyth Dental Infirmary Intra-pocket drug delivery devices for treatment of periodontal diseases
US4764377A (en) * 1983-10-07 1988-08-16 The Forsyth Dental Infirmary For Children Intra-pocket drug delivery devices for treatment of periodontal diseases
JPS60100516A (ja) * 1983-11-04 1985-06-04 Takeda Chem Ind Ltd 徐放型マイクロカプセルの製造法
US4568536A (en) * 1985-02-08 1986-02-04 Ethicon, Inc. Controlled release of pharmacologically active agents from an absorbable biologically compatible putty-like composition
US4650665A (en) * 1985-02-08 1987-03-17 Ethicon, Inc. Controlled release of pharmacologically active agents from an absorbable biologically compatible putty-like composition
US4670252A (en) * 1985-05-24 1987-06-02 The Procter & Gamble Company Treatment of oral diseases
US4624256A (en) * 1985-09-11 1986-11-25 Pfizer Hospital Products Group, Inc. Caprolactone polymers for suture coating
US4692328A (en) * 1985-09-24 1987-09-08 Dynatech Corporation Biologically useful polymer preparations
US4772484A (en) * 1985-09-24 1988-09-20 Kitchell Judith P Biologically useful polymer preparations
US5061281A (en) * 1985-12-17 1991-10-29 Allied-Signal Inc. Bioresorbable polymers and implantation devices thereof
FR2591892B1 (fr) * 1985-12-23 1988-09-16 Pf Medicament Association collagene/principe actifantiseptique et/ou anti-inflammatoire a titre de composition, son procede de preparation et son utilisation pour la fabrication d'une composition pharmaceutique
JPH0759496B2 (ja) * 1986-03-25 1995-06-28 ロ−ト製薬株式会社 歯周病治療剤
JPS62223112A (ja) * 1986-03-25 1987-10-01 Rooto Seiyaku Kk 歯周病治療剤
US4780320A (en) * 1986-04-29 1988-10-25 Pharmetrix Corp. Controlled release drug delivery system for the periodontal pocket
US4713243A (en) * 1986-06-16 1987-12-15 Johnson & Johnson Products, Inc. Bioadhesive extruded film for intra-oral drug delivery and process
JPH0617300B2 (ja) * 1986-09-22 1994-03-09 サンスタ−株式会社 歯周疾患治療用組成物
DE3635679A1 (de) * 1986-10-21 1988-05-05 Dynamit Nobel Ag Chirurgisches nahtmaterial
DE3708916A1 (de) * 1987-03-19 1988-09-29 Boehringer Ingelheim Kg Verfahren zur reinigung resorbierbarer polyester
JPH0645535B2 (ja) * 1987-05-20 1994-06-15 サンスタ−株式会社 歯槽骨代謝治療用組成物
IL86802A0 (en) * 1987-06-30 1988-11-30 Vipont Pharma Drug delivery devices
US4920203A (en) * 1987-12-17 1990-04-24 Allied-Signal Inc. Medical devices fabricated from homopolymers and copolymers having recurring carbonate units
US4900552A (en) * 1988-03-30 1990-02-13 Watson Laboratories, Inc. Mucoadhesive buccal dosage forms
US4938763B1 (en) † 1988-10-03 1995-07-04 Atrix Lab Inc Biodegradable in-situ forming implants and method of producing the same
US4969884A (en) * 1988-12-28 1990-11-13 Alza Corporation Osmotically driven syringe
US5077049A (en) † 1989-07-24 1991-12-31 Vipont Pharmaceutical, Inc. Biodegradable system for regenerating the periodontium
US5198220A (en) * 1989-11-17 1993-03-30 The Procter & Gamble Company Sustained release compositions for treating periodontal disease
US5084267A (en) * 1989-11-17 1992-01-28 The Procter & Gamble Company Sustained release compositions for treating periodontal disease
US5030216A (en) * 1989-12-15 1991-07-09 Alza Corporation Osmotically driven syringe
US5200195A (en) * 1991-12-06 1993-04-06 Alza Corporation Process for improving dosage form delivery kinetics

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9241512B2 (en) 2011-06-23 2016-01-26 British American Tobacco (Investments) Limited Filter material comprising polylactide fibres
US8851084B2 (en) 2011-07-19 2014-10-07 British American Tobacco (Investments) Limited Cellulose acetate compositions

Also Published As

Publication number Publication date
DE69309701T3 (de) 2005-03-24
ES2099977T5 (es) 2001-12-16
RU95109905A (ru) 1997-02-27
US5242910A (en) 1993-09-07
ATE151282T1 (de) 1997-04-15
DE69309701D1 (de) 1997-05-15
EP0664696B2 (de) 2001-10-17
EP0664696B1 (de) 1997-04-09
JPH08502289A (ja) 1996-03-12
EP0664696A1 (de) 1995-08-02
ES2099977T3 (es) 1997-06-01
WO1994008562A1 (en) 1994-04-28

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8332 No legal effect for de
8366 Restricted maintained after opposition proceedings
8339 Ceased/non-payment of the annual fee