DE69113148T2 - Thioxo-Heterocyclen und ihre pharmazeutische Verwendung. - Google Patents

Thioxo-Heterocyclen und ihre pharmazeutische Verwendung.

Info

Publication number
DE69113148T2
DE69113148T2 DE69113148T DE69113148T DE69113148T2 DE 69113148 T2 DE69113148 T2 DE 69113148T2 DE 69113148 T DE69113148 T DE 69113148T DE 69113148 T DE69113148 T DE 69113148T DE 69113148 T2 DE69113148 T2 DE 69113148T2
Authority
DE
Germany
Prior art keywords
formula
group
thioxo
methyl
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69113148T
Other languages
German (de)
English (en)
Other versions
DE69113148D1 (de
Inventor
Pierre Andre Raymond Bruneau
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca SAS
Syngenta Ltd
Original Assignee
Zeneca Pharma SA
Zeneca Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zeneca Pharma SA, Zeneca Ltd filed Critical Zeneca Pharma SA
Application granted granted Critical
Publication of DE69113148D1 publication Critical patent/DE69113148D1/de
Publication of DE69113148T2 publication Critical patent/DE69113148T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D245/00Heterocyclic compounds containing rings of more than seven members having two nitrogen atoms as the only ring hetero atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Quinoline Compounds (AREA)
  • Steroid Compounds (AREA)
  • Detergent Compositions (AREA)
  • Saccharide Compounds (AREA)
DE69113148T 1990-07-13 1991-07-09 Thioxo-Heterocyclen und ihre pharmazeutische Verwendung. Expired - Fee Related DE69113148T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP90402034 1990-07-13
EP91400079 1991-01-15

Publications (2)

Publication Number Publication Date
DE69113148D1 DE69113148D1 (de) 1995-10-26
DE69113148T2 true DE69113148T2 (de) 1996-03-28

Family

ID=26127361

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69113148T Expired - Fee Related DE69113148T2 (de) 1990-07-13 1991-07-09 Thioxo-Heterocyclen und ihre pharmazeutische Verwendung.

Country Status (22)

Country Link
US (1) US5240941A (enExample)
EP (1) EP0466452B1 (enExample)
JP (1) JPH04243877A (enExample)
KR (1) KR920002561A (enExample)
AT (1) ATE128133T1 (enExample)
AU (1) AU638579B2 (enExample)
CA (1) CA2046006A1 (enExample)
CS (1) CS214891A3 (enExample)
DE (1) DE69113148T2 (enExample)
DK (1) DK0466452T3 (enExample)
ES (1) ES2076472T3 (enExample)
FI (1) FI913369A7 (enExample)
GB (1) GB9113137D0 (enExample)
GR (1) GR3017453T3 (enExample)
HU (1) HUT61999A (enExample)
IE (1) IE912138A1 (enExample)
IL (1) IL98603A0 (enExample)
MX (1) MX174406B (enExample)
NO (1) NO912750L (enExample)
NZ (1) NZ238703A (enExample)
PT (1) PT98292A (enExample)
TW (1) TW235918B (enExample)

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US6677364B2 (en) * 1998-04-20 2004-01-13 G.D. Searle & Co. Substituted sulfonylphenylheterocycles as cyclooxygenase-2 and 5-lipoxygenase inhibitors
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US8158362B2 (en) 2005-03-30 2012-04-17 Decode Genetics Ehf. Methods of diagnosing susceptibility to myocardial infarction and screening for an LTA4H haplotype
WO2006068760A2 (en) 2004-11-19 2006-06-29 The Regents Of The University Of California Anti-inflammatory pyrazolopyrimidines
CA2909277A1 (en) 2006-04-04 2007-10-11 Kevan M. Shokat Kinase antagonists
WO2009046448A1 (en) 2007-10-04 2009-04-09 Intellikine, Inc. Chemical entities and therapeutic uses thereof
US8193182B2 (en) 2008-01-04 2012-06-05 Intellikine, Inc. Substituted isoquinolin-1(2H)-ones, and methods of use thereof
DK2240451T3 (da) 2008-01-04 2017-11-20 Intellikine Llc Isoquinolinonderivater substitueret med en purin, der er anvendelig som pi3k-inhibitorer
EP2252293B1 (en) 2008-03-14 2018-06-27 Intellikine, LLC Kinase inhibitors and methods of use
WO2009114874A2 (en) 2008-03-14 2009-09-17 Intellikine, Inc. Benzothiazole kinase inhibitors and methods of use
US9096611B2 (en) 2008-07-08 2015-08-04 Intellikine Llc Kinase inhibitors and methods of use
US20110224223A1 (en) 2008-07-08 2011-09-15 The Regents Of The University Of California, A California Corporation MTOR Modulators and Uses Thereof
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US9751888B2 (en) 2013-10-04 2017-09-05 Infinity Pharmaceuticals, Inc. Heterocyclic compounds and uses thereof
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Also Published As

Publication number Publication date
IE912138A1 (en) 1992-01-15
EP0466452A2 (en) 1992-01-15
JPH04243877A (ja) 1992-08-31
MX174406B (es) 1994-05-13
GR3017453T3 (en) 1995-12-31
HU912295D0 (en) 1991-12-30
NO912750D0 (no) 1991-07-12
GB9113137D0 (en) 1991-08-07
FI913369A7 (fi) 1992-01-14
NZ238703A (en) 1994-01-26
ES2076472T3 (es) 1995-11-01
HUT61999A (en) 1993-03-29
US5240941A (en) 1993-08-31
DK0466452T3 (da) 1996-01-02
IL98603A0 (en) 1992-07-15
PT98292A (pt) 1992-05-29
CS214891A3 (en) 1992-02-19
KR920002561A (ko) 1992-02-28
NO912750L (no) 1992-01-14
CA2046006A1 (en) 1992-01-14
EP0466452A3 (en) 1992-08-19
DE69113148D1 (de) 1995-10-26
ATE128133T1 (de) 1995-10-15
TW235918B (enExample) 1994-12-11
EP0466452B1 (en) 1995-09-20
AU7933791A (en) 1992-01-16
AU638579B2 (en) 1993-07-01
FI913369A0 (fi) 1991-07-11

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