CA2046006A1 - Thioxo heterocycles - Google Patents

Thioxo heterocycles

Info

Publication number
CA2046006A1
CA2046006A1 CA002046006A CA2046006A CA2046006A1 CA 2046006 A1 CA2046006 A1 CA 2046006A1 CA 002046006 A CA002046006 A CA 002046006A CA 2046006 A CA2046006 A CA 2046006A CA 2046006 A1 CA2046006 A1 CA 2046006A1
Authority
CA
Canada
Prior art keywords
formula
group
thioxo
methyl
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002046006A
Other languages
English (en)
French (fr)
Inventor
Pierre Andre Raymond Bruneau
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca SAS
Imperial Chemical Industries Ltd
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2046006A1 publication Critical patent/CA2046006A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D245/00—Heterocyclic compounds containing rings of more than seven members having two nitrogen atoms as the only ring hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Detergent Compositions (AREA)
  • Saccharide Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA002046006A 1990-07-13 1991-06-28 Thioxo heterocycles Abandoned CA2046006A1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP90402034.4 1990-07-13
EP90402034 1990-07-13
EP91400079.9 1991-01-15
EP91400079 1991-01-15

Publications (1)

Publication Number Publication Date
CA2046006A1 true CA2046006A1 (en) 1992-01-14

Family

ID=26127361

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002046006A Abandoned CA2046006A1 (en) 1990-07-13 1991-06-28 Thioxo heterocycles

Country Status (22)

Country Link
US (1) US5240941A (enExample)
EP (1) EP0466452B1 (enExample)
JP (1) JPH04243877A (enExample)
KR (1) KR920002561A (enExample)
AT (1) ATE128133T1 (enExample)
AU (1) AU638579B2 (enExample)
CA (1) CA2046006A1 (enExample)
CS (1) CS214891A3 (enExample)
DE (1) DE69113148T2 (enExample)
DK (1) DK0466452T3 (enExample)
ES (1) ES2076472T3 (enExample)
FI (1) FI913369A7 (enExample)
GB (1) GB9113137D0 (enExample)
GR (1) GR3017453T3 (enExample)
HU (1) HUT61999A (enExample)
IE (1) IE912138A1 (enExample)
IL (1) IL98603A0 (enExample)
MX (1) MX174406B (enExample)
NO (1) NO912750L (enExample)
NZ (1) NZ238703A (enExample)
PT (1) PT98292A (enExample)
TW (1) TW235918B (enExample)

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US8158362B2 (en) 2005-03-30 2012-04-17 Decode Genetics Ehf. Methods of diagnosing susceptibility to myocardial infarction and screening for an LTA4H haplotype
EP1831225A2 (en) 2004-11-19 2007-09-12 The Regents of the University of California Anti-inflammatory pyrazolopyrimidines
DK2004654T3 (da) 2006-04-04 2013-07-22 Univ California Pyrazolopyrimidin derivater til anvendelse som kinase antagonister
US20110160232A1 (en) 2007-10-04 2011-06-30 Pingda Ren Certain chemical entities and therapeutic uses thereof
CN101965335B (zh) 2008-01-04 2015-01-14 英特利凯恩有限责任公司 某些化学实体、组合物和方法
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US8993580B2 (en) 2008-03-14 2015-03-31 Intellikine Llc Benzothiazole kinase inhibitors and methods of use
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WO2010006072A2 (en) 2008-07-08 2010-01-14 The Regents Of The University Of California Mtor modulators and uses thereof
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AU2009305669A1 (en) 2008-10-16 2010-04-22 The Regents Of The University Of California Fused ring heteroaryl kinase inhibitors
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WO2012088266A2 (en) 2010-12-22 2012-06-28 Incyte Corporation Substituted imidazopyridazines and benzimidazoles as inhibitors of fgfr3
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JP6130305B2 (ja) 2011-02-23 2017-05-17 インテリカイン， エルエルシー キナーゼ阻害剤の組み合わせおよびそれらの使用
EP2734520B1 (en) 2011-07-19 2016-09-14 Infinity Pharmaceuticals, Inc. Heterocyclic compounds and uses thereof
HK1198475A1 (en) 2011-07-19 2015-05-08 无限药品股份有限公司 Heterocyclic compounds and uses thereof
US8785470B2 (en) 2011-08-29 2014-07-22 Infinity Pharmaceuticals, Inc. Heterocyclic compounds and uses thereof
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US8940742B2 (en) 2012-04-10 2015-01-27 Infinity Pharmaceuticals, Inc. Heterocyclic compounds and uses thereof
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WO2014026125A1 (en) 2012-08-10 2014-02-13 Incyte Corporation Pyrazine derivatives as fgfr inhibitors
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US9266892B2 (en) 2012-12-19 2016-02-23 Incyte Holdings Corporation Fused pyrazoles as FGFR inhibitors
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US10851105B2 (en) 2014-10-22 2020-12-01 Incyte Corporation Bicyclic heterocycles as FGFR4 inhibitors
UA121669C2 (uk) 2015-02-20 2020-07-10 Інсайт Корпорейшн Біциклічні гетероцикли як інгібітори fgfr
MA41551A (fr) 2015-02-20 2017-12-26 Incyte Corp Hétérocycles bicycliques utilisés en tant qu'inhibiteurs de fgfr4
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US10500178B2 (en) 2015-03-13 2019-12-10 The Board Of Trustees Of The Leland Stanford Junior University LTB4 inhibition to prevent and treat human lymphedema
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WO2017161116A1 (en) 2016-03-17 2017-09-21 Infinity Pharmaceuticals, Inc. Isotopologues of isoquinolinone and quinazolinone compounds and uses thereof as pi3k kinase inhibitors
WO2017214269A1 (en) 2016-06-08 2017-12-14 Infinity Pharmaceuticals, Inc. Heterocyclic compounds and uses thereof
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Also Published As

Publication number Publication date
US5240941A (en) 1993-08-31
TW235918B (enExample) 1994-12-11
ATE128133T1 (de) 1995-10-15
NZ238703A (en) 1994-01-26
JPH04243877A (ja) 1992-08-31
HU912295D0 (en) 1991-12-30
PT98292A (pt) 1992-05-29
NO912750L (no) 1992-01-14
HUT61999A (en) 1993-03-29
GB9113137D0 (en) 1991-08-07
DE69113148D1 (de) 1995-10-26
GR3017453T3 (en) 1995-12-31
DE69113148T2 (de) 1996-03-28
DK0466452T3 (da) 1996-01-02
ES2076472T3 (es) 1995-11-01
AU7933791A (en) 1992-01-16
FI913369A7 (fi) 1992-01-14
KR920002561A (ko) 1992-02-28
AU638579B2 (en) 1993-07-01
IE912138A1 (en) 1992-01-15
EP0466452A3 (en) 1992-08-19
EP0466452A2 (en) 1992-01-15
EP0466452B1 (en) 1995-09-20
FI913369A0 (fi) 1991-07-11
IL98603A0 (en) 1992-07-15
CS214891A3 (en) 1992-02-19
MX174406B (es) 1994-05-13
NO912750D0 (no) 1991-07-12

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Legal Events

Date Code Title Description
FZDE Discontinued