DE60309865T2 - Glycoprotein vi - fc fusions protein zur behandlung von gefässerkrankungen - Google Patents
Glycoprotein vi - fc fusions protein zur behandlung von gefässerkrankungen Download PDFInfo
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- DE60309865T2 DE60309865T2 DE60309865T DE60309865T DE60309865T2 DE 60309865 T2 DE60309865 T2 DE 60309865T2 DE 60309865 T DE60309865 T DE 60309865T DE 60309865 T DE60309865 T DE 60309865T DE 60309865 T2 DE60309865 T2 DE 60309865T2
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- gpvi
- fusion protein
- collagen
- platelet
- platelets
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- C—CHEMISTRY; METALLURGY
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- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
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- C12N2799/00—Uses of viruses
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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Applications Claiming Priority (3)
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| EP02012742 | 2002-06-07 | ||
| EP02012742A EP1369128A1 (en) | 2002-06-07 | 2002-06-07 | Inhibitors of glycoprotein VI and their therapeutic use |
| PCT/EP2003/005929 WO2003104282A2 (en) | 2002-06-07 | 2003-06-05 | Immunoadhesin comprising a glycoprotein vi domain |
Publications (2)
| Publication Number | Publication Date |
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| DE60309865D1 DE60309865D1 (de) | 2007-01-04 |
| DE60309865T2 true DE60309865T2 (de) | 2007-10-18 |
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| EP (4) | EP1369128A1 (enExample) |
| JP (1) | JP4722480B2 (enExample) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US20070071744A1 (en) | 2002-06-07 | 2007-03-29 | Gotz Munch | Agents which bind to epitopes of glycoprotein VI |
| WO2006061650A2 (en) * | 2004-12-10 | 2006-06-15 | Trigen Gmbh | Methods, products and uses involving platelets and/or the vasculature |
| EP1369128A1 (en) | 2002-06-07 | 2003-12-10 | Procorde GmbH | Inhibitors of glycoprotein VI and their therapeutic use |
| US7531178B2 (en) | 2002-06-07 | 2009-05-12 | Trigen Gmbh | Immunoadhesin comprising a glycoprotein VI domain |
| GB0511590D0 (en) * | 2005-06-07 | 2005-07-13 | Procorde Gmbh | Anti-thrombotic agents |
| EP1745076B1 (en) | 2004-04-29 | 2012-06-13 | Otsuka Pharmaceutical Co., Ltd. | Antibodies specific for glycoprotein vi and methods of producing these antibodies |
| US7645592B2 (en) | 2004-04-29 | 2010-01-12 | Otsuka Pharmaceutical Co., Ltd. | Glycoprotein VI antibodies and methods of use thereof |
| DK2412728T3 (en) | 2004-08-03 | 2015-04-07 | Innate Pharma | Therapeutic compositions for cancer, that target 4Ig-B7-H3 |
| FR2884831B1 (fr) * | 2005-04-22 | 2007-08-10 | Merck Sante Soc Par Actions Si | Methode de criblage de composes inhibiteurs de la mtp |
| WO2006117910A1 (ja) | 2005-04-28 | 2006-11-09 | Mochida Pharmaceutical Co., Ltd. | 抗血小板膜糖蛋白質ⅵモノクローナル抗体 |
| JP5224707B2 (ja) * | 2005-04-28 | 2013-07-03 | 持田製薬株式会社 | 抗血小板膜糖蛋白質ｖｉモノクローナル抗体 |
| EP1876240B1 (en) * | 2005-04-28 | 2012-08-22 | Mochida Pharmaceutical Co., Ltd. | Anti-human platelet membrane glycoprotein vi monoclonal antibody |
| US20110045504A1 (en) * | 2005-12-22 | 2011-02-24 | Noriaki Kume | Prognostic Prediction Method for Acute Coronary Syndrome |
| CN101874107A (zh) * | 2007-10-31 | 2010-10-27 | 大塚制药株式会社 | 糖蛋白ⅵ(gpvi)抑制剂的用途 |
| ES2569610T3 (es) * | 2008-12-04 | 2016-05-11 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Método para producir plaquetas |
| PL2429574T3 (pl) * | 2009-05-15 | 2015-12-31 | Univ Health Network | Kompozycje i sposoby leczenia nowotworów hematologicznych celujące w oddziaływanie SIRP-CD47 |
| EP2397495A1 (en) * | 2010-06-21 | 2011-12-21 | Sanofi | Novel antagonist antibodies and their Fab fragments against GPVI and uses thereof |
| EP2336188A1 (en) * | 2009-12-18 | 2011-06-22 | Sanofi-Aventis | Novel antagonist antibodies and their Fab fragments against GPVI and uses thereof |
| MA33930B1 (fr) * | 2009-12-18 | 2013-01-02 | Sanofi Sa | Nouveaux anticorps antagonistes contre gpvi et leurs fragments fab et utilisations de ceux-ci |
| EP2377888A1 (en) * | 2010-04-07 | 2011-10-19 | Corimmun GmbH | Fusion protein |
| JP6335189B2 (ja) | 2012-12-17 | 2018-05-30 | トリリアム・セラピューティクス・インコーポレイテッドＴｒｉｌｌｉｕｍ Ｔｈｅｒａｐｅｕｔｉｃｓ Ｉｎｃ． | ＳＩＲＰアルファ−Ｆｃ融合体でのＣＤ４７＋疾患細胞の治療 |
| CA2895693C (en) * | 2012-12-20 | 2017-02-28 | Fujimori Kogyo Co., Ltd. | Method for comprehensive assessment of platelet aggregation |
| EP3424957A1 (en) | 2017-07-03 | 2019-01-09 | advanceCOR GmbH | Fusion protein |
| CN110964119A (zh) * | 2019-12-05 | 2020-04-07 | 沣潮医药科技（上海）有限公司 | 抗疟二聚体免疫粘附素、药物组合物和用途 |
| JP2023513135A (ja) * | 2020-02-06 | 2023-03-30 | ベーリンガー インゲルハイム フェトメディカ ゲーエムベーハー | 抗ラブドウイルス抗体を検出するのに有用なポリペプチド |
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| US5156840A (en) * | 1982-03-09 | 1992-10-20 | Cytogen Corporation | Amine-containing porphyrin derivatives |
| ZA887365B (en) | 1987-10-02 | 1990-05-30 | Genentech Inc | Adheson variants |
| PT88641B (pt) | 1987-10-02 | 1993-04-30 | Genentech Inc | Metodo para a preparacao de uma variante de adesao |
| US5116964A (en) | 1989-02-23 | 1992-05-26 | Genentech, Inc. | Hybrid immunoglobulins |
| US6406697B1 (en) | 1989-02-23 | 2002-06-18 | Genentech, Inc. | Hybrid immunoglobulins |
| US5525491A (en) * | 1991-02-27 | 1996-06-11 | Creative Biomolecules, Inc. | Serine-rich peptide linkers |
| GB9806806D0 (en) | 1998-03-30 | 1998-05-27 | Univ Cambridge Tech | Peptides and uses thereof |
| GB9809951D0 (en) | 1998-05-08 | 1998-07-08 | Univ Cambridge Tech | Binding molecules |
| GB9810999D0 (en) * | 1998-05-21 | 1998-07-22 | Goken Joop | Materials and methods relating to the expression of genes |
| HK1045714B (zh) | 1999-05-07 | 2006-09-22 | 萨诺费－阿文蒂斯德国有限公司 | 重组血小板胶原受体糖蛋白vi及其药用 |
| US7291714B1 (en) * | 1999-06-30 | 2007-11-06 | Millennium Pharmaceuticals, Inc. | Glycoprotein VI and uses thereof |
| US20040001826A1 (en) | 1999-06-30 | 2004-01-01 | Millennium Pharmaceuticals, Inc. | Glycoprotein VI and uses thereof |
| US6245527B1 (en) | 1999-06-30 | 2001-06-12 | Millennium Pharmaceuticals, Inc. | Nucleic acid molecules encoding glycoprotein VI and recombinant uses thereof |
| WO2001016321A1 (en) | 1999-09-01 | 2001-03-08 | Otsuka Pharmaceutical Co., Ltd. | Platelet membrane glycoprotein vi (gpvi) dna and protein sequences, and uses thereof |
| EP1224942A1 (en) | 2001-01-23 | 2002-07-24 | Bernhard Dr. Nieswandt | Use of JAQ1 (monoclonal antibody anti GPVI) as a medicament for the protection against thrombotic diseases |
| PT1401853E (pt) | 2001-05-25 | 2010-12-07 | Univ Duke | Modulador de oligonucleotídeos |
| WO2003008454A2 (en) | 2001-07-18 | 2003-01-30 | Merck Patent Gmbh | Glycoprotein vi fusion proteins |
| GB0130543D0 (en) | 2001-12-20 | 2002-02-06 | Univ Cambridge Tech | Human antibodies and their use |
| GB0130832D0 (en) | 2001-12-22 | 2002-02-06 | Univ Reading | Modulation of the activity of the platelet endothelial cell adhesion molecule-1 (pecam-1) |
| GB0211750D0 (en) | 2002-05-22 | 2002-07-03 | Ouwehand Willem | Abnormal blood conditions |
| EP1369128A1 (en) | 2002-06-07 | 2003-12-10 | Procorde GmbH | Inhibitors of glycoprotein VI and their therapeutic use |
| US7531178B2 (en) | 2002-06-07 | 2009-05-12 | Trigen Gmbh | Immunoadhesin comprising a glycoprotein VI domain |
| EP1538165A1 (en) | 2003-12-03 | 2005-06-08 | Procorde GmbH | Inhibitors of glycoprotein VI based on monoclonal antibody hgp 5c4 |
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| EP1860118A2 (en) | 2007-11-28 |
| AU2003236704B2 (en) | 2010-07-08 |
| SI1511770T1 (sl) | 2007-04-30 |
| EP1511770B1 (en) | 2006-11-22 |
| JP2006512894A (ja) | 2006-04-20 |
| ES2276078T3 (es) | 2007-06-16 |
| CA2488630C (en) | 2011-07-05 |
| DK1860118T3 (en) | 2015-02-09 |
| DE60309865D1 (de) | 2007-01-04 |
| EP1369128A1 (en) | 2003-12-10 |
| WO2003104282A3 (en) | 2004-10-14 |
| WO2003104282A8 (en) | 2004-04-29 |
| AU2003250825A1 (en) | 2003-12-22 |
| ES2527717T3 (es) | 2015-01-28 |
| JP4722480B2 (ja) | 2011-07-13 |
| ZA200409776B (en) | 2007-02-28 |
| CN1668721B (zh) | 2012-11-14 |
| AU2003236704A1 (en) | 2003-12-22 |
| US20050079541A1 (en) | 2005-04-14 |
| CA2488630A1 (en) | 2003-12-18 |
| CN1668721A (zh) | 2005-09-14 |
| EP1511480A2 (en) | 2005-03-09 |
| WO2003103662A3 (en) | 2004-11-04 |
| EP1511770A2 (en) | 2005-03-09 |
| EP1860118A3 (en) | 2008-07-30 |
| AU2003250825A8 (en) | 2003-12-22 |
| WO2003104282A2 (en) | 2003-12-18 |
| US7514543B2 (en) | 2009-04-07 |
| WO2003103662A2 (en) | 2003-12-18 |
| ATE346095T1 (de) | 2006-12-15 |
| EP1860118B1 (en) | 2014-12-31 |
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Owner name: CORIMMUN GMBH, 82152 PLANEGG, DE |