DE60216457T2 - Carbamate verbindungen zur behandlung oder verhutung von psychotischen krankheiten - Google Patents

Carbamate verbindungen zur behandlung oder verhutung von psychotischen krankheiten Download PDF

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Publication number
DE60216457T2
DE60216457T2 DE60216457T DE60216457T DE60216457T2 DE 60216457 T2 DE60216457 T2 DE 60216457T2 DE 60216457 T DE60216457 T DE 60216457T DE 60216457 T DE60216457 T DE 60216457T DE 60216457 T2 DE60216457 T2 DE 60216457T2
Authority
DE
Germany
Prior art keywords
formula
group
phenyl
enantiomer
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60216457T
Other languages
German (de)
English (en)
Other versions
DE60216457D1 (de
Inventor
Carlos R. Ambler PLATA-SALAMAN
Boyu Lansdale Zhao
Roy E. Doylestown TWYMAN
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Pharmaceuticals Inc
Original Assignee
Ortho McNeil Pharmaceutical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho McNeil Pharmaceutical Inc filed Critical Ortho McNeil Pharmaceutical Inc
Publication of DE60216457D1 publication Critical patent/DE60216457D1/de
Application granted granted Critical
Publication of DE60216457T2 publication Critical patent/DE60216457T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/325Carbamic acids; Thiocarbamic acids; Anhydrides or salts thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE60216457T 2001-02-27 2002-02-21 Carbamate verbindungen zur behandlung oder verhutung von psychotischen krankheiten Expired - Lifetime DE60216457T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US81761 1998-05-20
US27188901P 2001-02-27 2001-02-27
US271889P 2001-02-27
PCT/US2002/006119 WO2002067927A1 (en) 2001-02-27 2002-02-21 Carbamate compounds for use in preventing or treating psychotic disorders
US10/081,761 US6541513B2 (en) 2001-02-27 2002-02-21 Carbamate compounds for use in preventing or treating psychotic disorders

Publications (2)

Publication Number Publication Date
DE60216457D1 DE60216457D1 (de) 2007-01-11
DE60216457T2 true DE60216457T2 (de) 2007-09-20

Family

ID=26765939

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60216457T Expired - Lifetime DE60216457T2 (de) 2001-02-27 2002-02-21 Carbamate verbindungen zur behandlung oder verhutung von psychotischen krankheiten

Country Status (25)

Country Link
US (1) US6541513B2 (enExample)
EP (1) EP1401424B1 (enExample)
JP (1) JP4276841B2 (enExample)
KR (1) KR100886578B1 (enExample)
CN (1) CN1262271C (enExample)
AR (1) AR032876A1 (enExample)
AT (1) ATE346597T1 (enExample)
AU (1) AU2002242296B2 (enExample)
BR (1) BR0207829A (enExample)
CA (1) CA2439480C (enExample)
CZ (1) CZ302412B6 (enExample)
DE (1) DE60216457T2 (enExample)
DK (1) DK1401424T3 (enExample)
ES (1) ES2275844T3 (enExample)
HU (1) HUP0303342A3 (enExample)
IL (2) IL157588A0 (enExample)
MX (1) MXPA03007722A (enExample)
NO (1) NO20033801L (enExample)
NZ (1) NZ527991A (enExample)
PL (1) PL365021A1 (enExample)
PT (1) PT1401424E (enExample)
RS (1) RS51056B (enExample)
RU (1) RU2302240C2 (enExample)
TW (1) TWI251486B (enExample)
WO (1) WO2002067927A1 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1305082E (pt) * 2000-07-21 2004-09-30 Ortho Mcneil Pharm Inc Compostos de carbamato para utilizacao na prevencao ou tratamento da dor neuropatica e dor associada a cefaleia de salvas e enxaqueca
IL157594A0 (en) 2001-02-27 2004-03-28 Ortho Mcneil Pharm Inc Carbamate compounds for use in preventing or treating anxiety disorders
PT1383489E (pt) * 2001-02-27 2007-06-21 Ortho Mcneil Pharm Inc Compostos carbamato para utilização na prevenção ou tratamento de distúrbios neurodegenerativos
HUP0401367A2 (hu) 2001-07-16 2004-12-28 Ortho-Mcneil Pharmaceutical, Inc. Karbamátvegyületek alkalmazása neuropátiás fájdalom, valamint cluster és migrénes fejfájással társuló fájdalom megelőzésére vagy kezelésére
WO2005107719A2 (en) * 2004-05-06 2005-11-17 Sandoz Ag Pharmaceutical composition comprising hydrophobic drug having improved solubility
CN101272776B (zh) * 2005-07-26 2012-10-03 詹森药业有限公司 氨基甲酸酯在制备治疗物质滥用相关疾病药物中的用途
US20080317883A1 (en) * 2006-10-30 2008-12-25 Yong Moon Choi Methods for treating depression
MX2009004798A (es) * 2006-10-31 2009-08-12 Janssen Pharmaceutica Nv Tratamiento de los trastornos generalizados del desarrollo.
US8609849B1 (en) 2010-11-30 2013-12-17 Fox Chase Chemical Diversity Center, Inc. Hydroxylated sulfamides exhibiting neuroprotective action and their method of use
CN105164103B (zh) * 2013-03-12 2019-12-06 比皮艾思药物研发有限公司 苯基氨基甲酸酯化合物和含有其的预防或治疗记忆缺失相关疾病的组合物
JP6062077B2 (ja) 2013-03-12 2017-01-18 バイオ−ファーム ソリューションズ カンパニー リミテッド 小児てんかん及びてんかん関連症侯群の予防又は治療用フェニルカルバメート化合物{phenylcarbamatecompoundsforuseinpreventingortreatingpediatricepilesyandepilesy−relatedsyndromes}

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US278380A (en) * 1883-05-29 Thermometer
US3313692A (en) * 1958-04-21 1967-04-11 Armour Pharma Method of inducing calming and muscle relaxation with carbamates
US3265728A (en) * 1962-07-18 1966-08-09 Armour Pharma Substituted phenethyl carbamates
DK0480939T3 (da) * 1989-06-09 1995-07-10 Upjohn Co Heterocycliske aminer med virkning på centralnervesystemet
US5492930A (en) * 1994-04-25 1996-02-20 Schering Corporation Method and formulation for treating CNS disorders
US5698588A (en) * 1996-01-16 1997-12-16 Yukong Limited Halogen substituted carbamate compounds from 2-phenyl-1,2-ethanediol

Also Published As

Publication number Publication date
US20020165272A1 (en) 2002-11-07
DE60216457D1 (de) 2007-01-11
CN1505507A (zh) 2004-06-16
AU2002242296B2 (en) 2006-06-29
ES2275844T3 (es) 2007-06-16
DK1401424T3 (da) 2007-02-26
EP1401424A1 (en) 2004-03-31
NZ527991A (en) 2005-04-29
CA2439480C (en) 2011-04-26
CZ302412B6 (cs) 2011-05-04
CN1262271C (zh) 2006-07-05
EP1401424B1 (en) 2006-11-29
WO2002067927A1 (en) 2002-09-06
BR0207829A (pt) 2004-06-22
TWI251486B (en) 2006-03-21
CZ20032297A3 (cs) 2004-06-16
HUP0303342A2 (hu) 2004-01-28
NO20033801D0 (no) 2003-08-26
KR100886578B1 (ko) 2009-03-05
RS51056B (sr) 2010-10-31
MXPA03007722A (es) 2004-11-12
ATE346597T1 (de) 2006-12-15
US6541513B2 (en) 2003-04-01
IL157588A0 (en) 2004-03-28
PT1401424E (pt) 2007-02-28
CA2439480A1 (en) 2002-09-06
KR20030076713A (ko) 2003-09-26
JP2004523556A (ja) 2004-08-05
AR032876A1 (es) 2003-11-26
RU2302240C2 (ru) 2007-07-10
JP4276841B2 (ja) 2009-06-10
NO20033801L (no) 2003-10-22
IL157588A (en) 2009-12-24
HUP0303342A3 (en) 2012-07-30
RU2003128983A (ru) 2005-03-10
RS67503A (sr) 2006-12-15
PL365021A1 (en) 2004-12-27

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