DE60213826T8 - Entwicklung neuer molekularer funktionen - Google Patents

Entwicklung neuer molekularer funktionen Download PDF

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Publication number
DE60213826T8
DE60213826T8 DE60213826T DE60213826T DE60213826T8 DE 60213826 T8 DE60213826 T8 DE 60213826T8 DE 60213826 T DE60213826 T DE 60213826T DE 60213826 T DE60213826 T DE 60213826T DE 60213826 T8 DE60213826 T8 DE 60213826T8
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Prior art keywords
molecules
amplification
natural
nucleic acid
selection
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DE60213826T
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DE60213826T3 (de
DE60213826T2 (de
DE60213826D1 (de
Inventor
R. David Lexington LIU
J. Zev Somerville GARTNER
W. Mattew Cambridge KANAN
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Harvard College
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Harvard College
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Publication of DE60213826T2 publication Critical patent/DE60213826T2/de
Publication of DE60213826T8 publication Critical patent/DE60213826T8/de
Publication of DE60213826T3 publication Critical patent/DE60213826T3/de
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Expired - Lifetime legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1068—Template (nucleic acid) mediated chemical library synthesis, e.g. chemical and enzymatical DNA-templated organic molecule synthesis, libraries prepared by non ribosomal polypeptide synthesis [NRPS], DNA/RNA-polymerase mediated polypeptide synthesis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/30—Nucleotides
    • C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Mycology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Steroid Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Peptides Or Proteins (AREA)
DE60213826T 2001-03-19 2002-03-19 Entwicklung neuer molekularer funktionen Expired - Lifetime DE60213826T3 (de)

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
US27708101P 2001-03-19 2001-03-19
US27709401P 2001-03-19 2001-03-19
US277081P 2001-03-19
US277094P 2001-03-19
US30669101P 2001-07-20 2001-07-20
US306691P 2001-07-20
US101030 2002-03-19
US10/101,030 US7070928B2 (en) 2001-03-19 2002-03-19 Evolving new molecular function
EP02753671.3A EP1423400B2 (de) 2001-03-19 2002-03-19 Entwicklung neuer molekularer funktionen
PCT/US2002/008546 WO2002074929A2 (en) 2001-03-19 2002-03-19 Evolving new molecular function

Publications (4)

Publication Number Publication Date
DE60213826D1 DE60213826D1 (de) 2006-09-21
DE60213826T2 DE60213826T2 (de) 2007-03-29
DE60213826T8 true DE60213826T8 (de) 2007-08-30
DE60213826T3 DE60213826T3 (de) 2013-10-17

Family

ID=27493169

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60213826T Expired - Lifetime DE60213826T3 (de) 2001-03-19 2002-03-19 Entwicklung neuer molekularer funktionen

Country Status (12)

Country Link
US (7) US7070928B2 (de)
EP (3) EP1832567A3 (de)
JP (4) JP4128453B2 (de)
AT (1) ATE335754T1 (de)
AU (2) AU2002306777C1 (de)
CA (1) CA2441820C (de)
DE (1) DE60213826T3 (de)
DK (1) DK1423400T4 (de)
ES (1) ES2271306T5 (de)
IL (4) IL158000A0 (de)
PT (1) PT1423400E (de)
WO (1) WO2002074929A2 (de)

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US20050142583A1 (en) 2005-06-30
IL158000A0 (en) 2004-03-28
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