DE602004029393D1 - Tgf-beta1-bindende und geträgerte peptide - Google Patents
Tgf-beta1-bindende und geträgerte peptideInfo
- Publication number
- DE602004029393D1 DE602004029393D1 DE602004029393T DE602004029393T DE602004029393D1 DE 602004029393 D1 DE602004029393 D1 DE 602004029393D1 DE 602004029393 T DE602004029393 T DE 602004029393T DE 602004029393 T DE602004029393 T DE 602004029393T DE 602004029393 D1 DE602004029393 D1 DE 602004029393D1
- Authority
- DE
- Germany
- Prior art keywords
- peptides
- supported
- tgf
- preferred embodiments
- supported peptides
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 8
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 8
- 101710167800 Capsid assembly scaffolding protein Proteins 0.000 abstract 2
- 101710130420 Probable capsid assembly scaffolding protein Proteins 0.000 abstract 2
- 101710204410 Scaffold protein Proteins 0.000 abstract 2
- 201000010099 disease Diseases 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 241001303601 Rosacea Species 0.000 abstract 1
- 230000002062 proliferating effect Effects 0.000 abstract 1
- 201000004700 rosacea Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/81—Protease inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/81—Protease inhibitors
- C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
- C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Rheumatology (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Dermatology (AREA)
- Physics & Mathematics (AREA)
- Pulmonology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Pain & Pain Management (AREA)
- Immunology (AREA)
- Cardiology (AREA)
- Physical Education & Sports Medicine (AREA)
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US51815403P | 2003-11-06 | 2003-11-06 | |
| US52040303P | 2003-11-13 | 2003-11-13 | |
| US53118903P | 2003-12-19 | 2003-12-19 | |
| US53095403P | 2003-12-19 | 2003-12-19 | |
| US53120703P | 2003-12-19 | 2003-12-19 | |
| PCT/US2004/036979 WO2005046710A2 (en) | 2003-11-06 | 2004-11-06 | Tgf-beta binding and supported peptides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE602004029393D1 true DE602004029393D1 (de) | 2010-11-11 |
Family
ID=34596198
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE602004029393T Expired - Lifetime DE602004029393D1 (de) | 2003-11-06 | 2004-11-06 | Tgf-beta1-bindende und geträgerte peptide |
| DE602004029812T Expired - Lifetime DE602004029812D1 (de) | 2003-11-06 | 2004-11-06 | Fgf-5-bindende und geträgerte peptide |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE602004029812T Expired - Lifetime DE602004029812D1 (de) | 2003-11-06 | 2004-11-06 | Fgf-5-bindende und geträgerte peptide |
Country Status (9)
| Country | Link |
|---|---|
| US (8) | US20080113917A1 (de) |
| EP (4) | EP1692160B1 (de) |
| JP (2) | JP4843497B2 (de) |
| AT (4) | ATE486087T1 (de) |
| CA (1) | CA2544820C (de) |
| DE (2) | DE602004029393D1 (de) |
| DK (2) | DK1680507T3 (de) |
| ES (1) | ES2375360T3 (de) |
| WO (4) | WO2005046709A2 (de) |
Families Citing this family (116)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK1680507T3 (da) * | 2003-11-06 | 2011-10-10 | Danisco Us Inc | Bakterieekspression af proteaseinhibitorer og varianter deraf |
| ATE555119T1 (de) * | 2003-11-06 | 2012-05-15 | Danisco Us Inc | Expression von proteaseinhibitoren und varianten davon in filamentösen pilzen |
| US20110098184A1 (en) * | 2004-10-15 | 2011-04-28 | Day Anthony G | Competitve differntial screeing |
| BRPI0613548A2 (pt) * | 2005-05-05 | 2011-01-18 | Genencor Int | composições de cuidado pessoal e métodos para seu uso |
| DK1904529T3 (da) * | 2005-06-10 | 2010-11-15 | Medical Res Council | Anvendelse af Stefin A som et scaffoldprotein |
| CN101273053A (zh) * | 2005-07-13 | 2008-09-24 | 安进芒廷维尤公司 | Il-6结合蛋白 |
| GB0601684D0 (en) * | 2006-01-27 | 2006-03-08 | Reckitt Benckiser Uk Ltd | Composition, process for preparation and method of use |
| WO2007092465A2 (en) * | 2006-02-07 | 2007-08-16 | Dyao Pharmaceutical Corporation | Topical delivery compositions |
| CA2960817A1 (en) * | 2006-09-16 | 2008-03-20 | Soy Labs Llc | Products and methods using soy 2s albumin |
| US20080124355A1 (en) | 2006-09-22 | 2008-05-29 | David Gordon Bermudes | Live bacterial vaccines for viral infection prophylaxis or treatment |
| US20080090745A1 (en) * | 2006-10-13 | 2008-04-17 | Fox Bryan P | Expression of Streptomyces subtilism inhibitor (SSI) proteins in Bacillus and Streptomyces sp. |
| CA2672603A1 (en) * | 2006-12-18 | 2008-06-26 | Danisco Us, Inc., Genencor Division | Novel laccases, compositions and methods of use |
| BRPI0722093A2 (pt) | 2006-12-21 | 2014-04-01 | Danisco Us Inc Genencor Div | Composições e usos para um polipeptídeo de alfa-amilase da espécie bacillus 195 |
| DK2171055T3 (en) * | 2007-06-06 | 2016-06-27 | Danisco Us Inc | Process for the improvement of protein many properties |
| US20090048136A1 (en) * | 2007-08-15 | 2009-02-19 | Mcdonald Hugh C | Kappa-carrageenase and kappa-carrageenase-containing compositions |
| BRPI0819151A2 (pt) * | 2007-10-31 | 2014-10-14 | Danisco Us Inc | Uso e produção de metaloproteases neutras em um resíduo isento de serina proteases |
| WO2009058956A1 (en) * | 2007-11-01 | 2009-05-07 | Danisco Us, Inc. | Signal sequences and co-expressed chaperones for improving protein production in a host cell |
| GB0722332D0 (en) * | 2007-11-14 | 2007-12-27 | Reckitt Benckiser Uk Ltd | Personal care article |
| CN101952308A (zh) * | 2008-01-29 | 2011-01-19 | 丹尼斯科美国公司 | 链霉菌枯草杆菌蛋白酶抑制剂(ssi)蛋白在芽孢杆菌属和链霉菌属物种中的表达 |
| JP2011510681A (ja) | 2008-02-04 | 2011-04-07 | ダニスコ・ユーエス・インク | 改変された特性をもつts23アルファ‐アミラーゼ変異体 |
| US7772181B2 (en) | 2008-10-15 | 2010-08-10 | Danisco Us Inc. | Personal care compositions comprising modified variant Bowman Birk Protease Inhibitors |
| AU2008362898B2 (en) | 2008-10-15 | 2013-02-28 | Danisco Us Inc. | Modified variant Bowman Birk Protease inhibitors |
| US7803902B2 (en) | 2008-10-15 | 2010-09-28 | Danisco Us Inc. | Modified variant bowman birk protease inhibitors |
| US8241623B1 (en) | 2009-02-09 | 2012-08-14 | David Bermudes | Protease sensitivity expression system |
| US20120172275A1 (en) | 2009-03-10 | 2012-07-05 | Danisco Us Inc. | Bacillus Megaterium Strain DSM90-Related Alpha-Amylases, and Methods of Use, Thereof |
| US20100247693A1 (en) * | 2009-03-24 | 2010-09-30 | Marini Jan L | Cosmetic formulation to treat rosacea telangiectasia |
| BRPI1012590A2 (pt) | 2009-04-08 | 2015-09-22 | Danisco Us Inc Genencor Div | alfa-amilases relacionadas à cepa wdg-195 de halomonas e métodos de uso das mesmas |
| DK2421973T3 (en) | 2009-04-24 | 2018-07-30 | Danisco Us Inc | PROTEAS WITH MODIFIED PRO AREAS |
| MX2011011619A (es) * | 2009-05-01 | 2012-02-28 | Signal Invest And Man Co | Composicion antimicrobiana hidratante. |
| AR076941A1 (es) | 2009-06-11 | 2011-07-20 | Danisco Us Inc | Cepa de bacillus para una mayor produccion de proteina |
| US20110052676A1 (en) * | 2009-09-01 | 2011-03-03 | James Vincent Gruber | Composition For Delaying Cellular Senescence |
| EP2478003A4 (de) | 2009-09-15 | 2013-05-29 | Five Prime Therapeutics Inc | Haarwuchsverfahren unter verwendung extrazellulärer fgfr4-domänen |
| GB0921001D0 (en) * | 2009-11-30 | 2010-01-13 | Aqua Bio Technology Asa | Products and uses |
| DK3190183T3 (da) | 2009-12-09 | 2019-10-14 | Danisco Us Inc | Sammensætninger og fremgangsmåder omfattende proteasevarianter |
| US8685931B2 (en) | 2009-12-17 | 2014-04-01 | Five Prime Therapeutics, Inc. | Hair growth methods using FGFR3 extracellular domains |
| WO2011082359A1 (en) * | 2009-12-30 | 2011-07-07 | Solae, Llc | Purified kunitz trypsin inhibitor proteins isolated from a soy processing stream |
| US9597379B1 (en) | 2010-02-09 | 2017-03-21 | David Gordon Bermudes | Protease inhibitor combination with therapeutic proteins including antibodies |
| US8524220B1 (en) | 2010-02-09 | 2013-09-03 | David Gordon Bermudes | Protease inhibitor: protease sensitivity expression system composition and methods improving the therapeutic activity and specificity of proteins delivered by bacteria |
| US8771669B1 (en) | 2010-02-09 | 2014-07-08 | David Gordon Bermudes | Immunization and/or treatment of parasites and infectious agents by live bacteria |
| ES2574056T3 (es) | 2010-03-31 | 2016-06-14 | Agency For Science, Technology And Research | Péptido/peptoide anfifílico lineal e hidrogel que comprende el mismo |
| US9687591B2 (en) | 2010-03-31 | 2017-06-27 | Agency For Science, Technology And Research | Building stratified biomimetic tissues and organs using crosslinked ultrashort peptide hydrogel membranes |
| US8999916B2 (en) | 2010-03-31 | 2015-04-07 | Agency For Science, Technology And Research | Crosslinked peptide hydrogels |
| WO2011130222A2 (en) | 2010-04-15 | 2011-10-20 | Danisco Us Inc. | Compositions and methods comprising variant proteases |
| MX339810B (es) | 2010-05-06 | 2016-06-09 | The Procter & Gamble Company * | Productos de consumo con variantes de la proteasa. |
| US8481038B2 (en) | 2010-11-15 | 2013-07-09 | Five Prime Therapeutics, Inc. | Treatment of cancer with elevated dosages of soluble FGFR1 fusion proteins |
| TR201901382T4 (tr) | 2011-05-05 | 2019-02-21 | Danisco Inc | Serin proteaz varyantlarını içeren bileşimler ve yöntemler. |
| WO2012151480A2 (en) | 2011-05-05 | 2012-11-08 | The Procter & Gamble Company | Compositions and methods comprising serine protease variants |
| US20140187468A1 (en) | 2011-08-31 | 2014-07-03 | Danisco Us Inc. | Compositions and Methods Comprising a Lipolytic Enzyme Variant |
| WO2013096653A1 (en) | 2011-12-22 | 2013-06-27 | Danisco Us Inc. | Compositions and methods comprising a lipolytic enzyme variant |
| US9120841B2 (en) | 2012-09-28 | 2015-09-01 | Agency For Science, Technology And Research | Amphiphilic linear peptidepeptoid and hydrogel comprising the same |
| EP3842531A1 (de) | 2012-10-12 | 2021-06-30 | Danisco US Inc. | Zusammensetzungen und verfahren mit einer variante eines lipolytischen enzyms |
| KR20150082502A (ko) | 2012-11-05 | 2015-07-15 | 다니스코 유에스 인크. | 써몰리신 프로테아제 변이체를 포함하는 조성물 및 방법 |
| EP2935573A1 (de) | 2012-12-19 | 2015-10-28 | Danisco US Inc. | Neuartige mannase, zusammensetzungen und verfahren zur verwendung davon |
| US9593339B1 (en) | 2013-02-14 | 2017-03-14 | David Gordon Bermudes | Bacteria carrying bacteriophage and protease inhibitors for the treatment of disorders and methods of treatment |
| US20160108387A1 (en) | 2013-05-29 | 2016-04-21 | Danisco Us Inc. | Novel metalloproteases |
| JP2016526880A (ja) | 2013-05-29 | 2016-09-08 | ダニスコ・ユーエス・インク | 新規メタロプロテアーゼ |
| EP3260538B1 (de) | 2013-05-29 | 2021-04-14 | Danisco US Inc. | Neuartige metalloproteasen |
| WO2014194032A1 (en) | 2013-05-29 | 2014-12-04 | Danisco Us Inc. | Novel metalloproteases |
| ES2797483T3 (es) | 2013-07-19 | 2020-12-02 | Danisco Us Inc | Composiciones y métodos comprendiendo una variante de enzima lipolítica |
| EP3653707B1 (de) | 2013-09-12 | 2025-07-16 | Danisco US Inc. | Zusammensetzungen und verfahren mit lg12-klade-protease-varianten |
| KR20160068855A (ko) | 2013-10-11 | 2016-06-15 | 제넨테크, 인크. | Nsp4 억제제 및 사용 방법 |
| US20160250298A1 (en) | 2013-11-01 | 2016-09-01 | Spherium Biomed S.L. | Inclusion bodies for transdermal delivery of therapeutic and cosmetic agents |
| EP3080262B1 (de) | 2013-12-13 | 2019-02-06 | Danisco US Inc. | Serinproteaseenzymen von bacillus |
| CN106029881B (zh) | 2013-12-13 | 2023-01-10 | 丹尼斯科美国公司 | 吉氏芽孢杆菌-进化枝的丝氨酸蛋白酶 |
| US9737592B1 (en) * | 2014-02-14 | 2017-08-22 | David Gordon Bermudes | Topical and orally administered protease inhibitors and bacterial vectors for the treatment of disorders and methods of treatment |
| DK3119884T3 (da) | 2014-03-21 | 2019-10-14 | Danisco Us Inc | Serinproteaser af bacillus-arter |
| DK3207129T3 (da) | 2014-10-17 | 2020-02-24 | Danisco Us Inc | Serinproteaser af bacillus-arten |
| EP4403631A3 (de) | 2014-10-27 | 2024-10-30 | Danisco US Inc. | Serinproteasen |
| DK3212662T3 (da) | 2014-10-27 | 2020-07-20 | Danisco Us Inc | Serinproteaser |
| US20170335306A1 (en) | 2014-10-27 | 2017-11-23 | Danisco Us Inc. | Serine proteases |
| EP3224357A1 (de) | 2014-10-27 | 2017-10-04 | Danisco US Inc. | Serinproteasen aus einer bacillus-spezies |
| EP3550017B1 (de) | 2014-10-27 | 2021-07-14 | Danisco US Inc. | Serinproteasen |
| EP3268471B1 (de) | 2015-03-12 | 2019-08-28 | Danisco US Inc. | Zusammensetzungen und verfahren mit lg12-klade-proteasevarianten |
| US10676723B2 (en) | 2015-05-11 | 2020-06-09 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
| JP7274819B2 (ja) | 2015-05-13 | 2023-05-17 | ダニスコ・ユーエス・インク | AprL-CLADEプロテアーゼ変異体及びその使用 |
| JP7134629B2 (ja) | 2015-06-17 | 2022-09-12 | ダニスコ・ユーエス・インク | 改変プロペプチド領域を備えるプロテアーゼ |
| US11499146B2 (en) | 2015-06-17 | 2022-11-15 | Danisco Us Inc. | Bacillus gibsonii-clade serine proteases |
| CN107022432A (zh) * | 2016-01-29 | 2017-08-08 | 高露洁-棕榄公司 | 清洁组合物 |
| US20190136218A1 (en) | 2016-05-05 | 2019-05-09 | Danisco Us Inc | Protease variants and uses thereof |
| MX2018014768A (es) | 2016-05-31 | 2019-03-06 | Danisco Us Inc | Variantes de proteasa y sus usos. |
| WO2017219011A1 (en) | 2016-06-17 | 2017-12-21 | Danisco Us Inc | Protease variants and uses thereof |
| US11180535B1 (en) | 2016-12-07 | 2021-11-23 | David Gordon Bermudes | Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria |
| US11129906B1 (en) | 2016-12-07 | 2021-09-28 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
| US11946081B2 (en) | 2016-12-21 | 2024-04-02 | Danisco Us Inc. | Bacillus gibsonii-clade serine proteases |
| DK3559227T3 (da) | 2016-12-21 | 2025-05-05 | Danisco Us Inc | Proteasevarianter og anvendelser deraf |
| US11298391B1 (en) * | 2017-04-27 | 2022-04-12 | Lorenol Laboratories, Inc. | Topical skin health improvement compositions and administrations thereof |
| CN111373039A (zh) | 2017-11-29 | 2020-07-03 | 丹尼斯科美国公司 | 具有改善的稳定性的枯草杆菌蛋白酶变体 |
| EP3799601A1 (de) | 2018-06-19 | 2021-04-07 | Danisco US Inc. | Subtilisinvarianten |
| WO2019245704A1 (en) | 2018-06-19 | 2019-12-26 | Danisco Us Inc | Subtilisin variants |
| US20240279627A1 (en) | 2018-08-30 | 2024-08-22 | Danisco Us Inc | Compositions comprising a lipolytic enzyme variant and methods of use thereof |
| CN112368388B (zh) * | 2018-10-31 | 2024-01-02 | 青岛蔚蓝生物集团有限公司 | 一种生产具有蛋白酶抗性的洗涤用酶的方法 |
| EP3887515A1 (de) | 2018-11-28 | 2021-10-06 | Danisco US Inc. | Subtilisin-varianten mit verbesserter stabilität |
| WO2020242858A1 (en) | 2019-05-24 | 2020-12-03 | Danisco Us Inc | Subtilisin variants and methods of use |
| CN112062828B (zh) * | 2019-06-10 | 2022-04-29 | 温州医科大学 | Fgf-5多肽抑制剂及其生发应用 |
| US12285437B2 (en) | 2019-10-30 | 2025-04-29 | The Research Foundation For The State University Of New York | Reversing the undesirable pH-profile of doxorubicin via activation of a disubstituted maleamic acid prodrug at tumor acidity |
| EP4090727A1 (de) | 2020-01-13 | 2022-11-23 | Danisco US Inc. | Zusammensetzungen mit einer lipolytischen enzymvariante und verfahren zur verwendung davon |
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| EP4204553A1 (de) | 2020-08-27 | 2023-07-05 | Danisco US Inc. | Enzyme und enzymzusammensetzungen zur reinigung |
| GB202019817D0 (en) * | 2020-12-15 | 2021-01-27 | Univ Oxford Innovation Ltd | Ligand-binding polypeptides and uses thereof |
| CN113307857B (zh) * | 2021-01-14 | 2022-11-01 | 艾时斌 | 从表皮生长因子、凝集素和Tat蛋白衍生的支架蛋白 |
| EP4363565A1 (de) | 2021-06-30 | 2024-05-08 | Danisco US Inc. | Variante lipasen und verwendungen davon |
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| US20250051748A1 (en) | 2021-12-16 | 2025-02-13 | Danisco Us Inc. | Subtilisin variants and methods of use |
| EP4448712A1 (de) | 2021-12-16 | 2024-10-23 | The Procter & Gamble Company | Protease enthaltende zusammensetzung für geschirrspülmaschinen |
| WO2023114794A1 (en) | 2021-12-16 | 2023-06-22 | The Procter & Gamble Company | Fabric and home care composition comprising a protease |
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| JP2025529133A (ja) | 2022-09-02 | 2025-09-04 | ダニスコ・ユーエス・インク | サブチリシン変異体及びそれに関連する方法 |
| CN120303400A (zh) | 2022-11-09 | 2025-07-11 | 丹尼斯科美国公司 | 枯草杆菌蛋白酶变体和使用方法 |
| WO2024163695A1 (en) | 2023-02-01 | 2024-08-08 | The Procter & Gamble Company | Detergent compositions containing enzymes |
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| WO2024186819A1 (en) | 2023-03-06 | 2024-09-12 | Danisco Us Inc. | Subtilisin variants and methods of use |
| WO2025071996A1 (en) | 2023-09-28 | 2025-04-03 | Danisco Us Inc. | Variant cutinase enzymes with improved solubility and uses thereof |
| WO2025085351A1 (en) | 2023-10-20 | 2025-04-24 | Danisco Us Inc. | Subtilisin variants and methods of use |
Family Cites Families (57)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3755560A (en) * | 1971-06-30 | 1973-08-28 | Dow Chemical Co | Nongreasy cosmetic lotions |
| DE2437090A1 (de) * | 1974-08-01 | 1976-02-19 | Hoechst Ag | Reinigungsmittel |
| JPS51125468A (en) | 1975-03-27 | 1976-11-01 | Sanyo Chem Ind Ltd | Method of preparing resins of high water absorbency |
| US4152416A (en) * | 1976-09-17 | 1979-05-01 | Marra Dorothea C | Aerosol antiperspirant compositions delivering astringent salt with low mistiness and dustiness |
| US4421769A (en) * | 1981-09-29 | 1983-12-20 | The Procter & Gamble Company | Skin conditioning composition |
| FI69503C (fi) * | 1984-03-13 | 1986-02-10 | Neste Oy | Ytbelagd bergsbehaollare eller tunnel |
| US5411873A (en) * | 1984-05-29 | 1995-05-02 | Genencor, Inc. | Process for producing heterologous polypeptides |
| US4965188A (en) | 1986-08-22 | 1990-10-23 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme |
| US4683202A (en) * | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US4683195A (en) * | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US5679543A (en) * | 1985-08-29 | 1997-10-21 | Genencor International, Inc. | DNA sequences, vectors and fusion polypeptides to increase secretion of desired polypeptides from filamentous fungi |
| US4937370A (en) * | 1987-06-02 | 1990-06-26 | The Procter & Gamble Company | Novel chromophores, sunscreen compositions and methods for preventing sunburn |
| US4999186A (en) * | 1986-06-27 | 1991-03-12 | The Procter & Gamble Company | Novel sunscreen agents, sunscreen compositions and methods for preventing sunburn |
| US5322770A (en) * | 1989-12-22 | 1994-06-21 | Hoffman-Laroche Inc. | Reverse transcription with thermostable DNA polymerases - high temperature reverse transcription |
| WO1988002025A1 (en) * | 1986-09-17 | 1988-03-24 | Sri International | Expression vectors for bacilli |
| US5087372A (en) * | 1989-03-24 | 1992-02-11 | Asahi Kasei Kogyo Kabushiki Kaisha | Method for removing heavy metal ions from contaminated water and a porous membrane usable therefor |
| US5011681A (en) * | 1989-10-11 | 1991-04-30 | Richardson-Vicks, Inc. | Facial cleansing compositions |
| US5073371A (en) * | 1990-11-30 | 1991-12-17 | Richardson-Vicks, Inc. | Leave-on facial emulsion compositions |
| US5073372A (en) * | 1990-11-30 | 1991-12-17 | Richardson-Vicks, Inc. | Leave-on facial emulsion compositions |
| US5436228A (en) * | 1990-12-12 | 1995-07-25 | Postlethwaite; Arnold E. | Chemotactic wound healing peptides |
| US5429950A (en) * | 1992-03-30 | 1995-07-04 | Genencor International, Inc. | Heterologous gene expression in bacillus subtilis: fusion approach |
| GB9415421D0 (en) | 1994-07-30 | 1994-09-21 | Procter & Gamble | Cosmetic compositions and processes for manufacture thereof |
| ATE178203T1 (de) | 1994-11-28 | 1999-04-15 | Procter & Gamble | Topische hautpflegemittel enthaltend verdickte polyolestern von carbonsaüren als haut konditionierende agentien |
| ZA963348B (en) * | 1996-03-12 | 1996-11-04 | Genencor Int | Alkaline cellulase and method of producing same |
| WO1997038708A1 (en) * | 1996-04-18 | 1997-10-23 | The General Hospital Corporation | Modulating epithelial-mesenchymal interactions |
| US5827508A (en) * | 1996-09-27 | 1998-10-27 | The Procter & Gamble Company | Stable photoprotective compositions |
| US5976838A (en) * | 1996-12-18 | 1999-11-02 | Genetics Institute, Inc. | Secreted proteins and polynucleotides encoding them |
| CA2272306A1 (en) | 1996-11-22 | 1998-05-28 | The Procter & Gamble Company | Cosmetic compositions |
| DE19735587B4 (de) * | 1997-08-16 | 2012-03-22 | Eberhard-Karls-Universität Tübingen Universitätsklinikum | Peptid mit radioprotektiver Wirkung, dieses enthaltende kosmetische oder pharmazeutische Zusammensetzung, für dieses kodierende Nukleinsäure, Herstellungsverfahren für dieses Peptid und die Verwendung als radioprotektives Agens |
| US6747137B1 (en) * | 1998-02-13 | 2004-06-08 | Genome Therapeutics Corporation | Nucleic acid sequences relating to Candida albicans for diagnostics and therapeutics |
| EE200100040A (et) * | 1998-07-20 | 2002-06-17 | M & E Biotech A/S | Meetod raku fenotüüpi muutva modulaatori identifitseerimiseks ja valmistamiseks, sihtmärkbiomolekulide eraldamiseks ja/või samastamiseks ning meditsiinitoote arendamiseks ja valmistamiseks |
| US5989528A (en) | 1998-07-30 | 1999-11-23 | The Procter & Gamble Company | Sunscreen compositions |
| US5935556A (en) * | 1998-07-30 | 1999-08-10 | The Procter & Gamble Company | Sunscreen compositions |
| JP3855042B2 (ja) * | 1998-09-22 | 2006-12-06 | 独立行政法人産業技術総合研究所 | 毛髪の鑑別法 |
| US5972316A (en) * | 1998-10-16 | 1999-10-26 | The Procter & Gamble Company | UV protection compositions |
| US5968485A (en) * | 1998-10-16 | 1999-10-19 | The Procter & Gamble Company | UV protection compositions |
| AU1275599A (en) | 1998-10-23 | 2000-05-15 | Procter & Gamble Company, The | Skin care compositions |
| GB9825854D0 (en) * | 1998-11-25 | 1999-01-20 | Univ Bristol | Peptide |
| JP3106191B1 (ja) * | 1999-03-30 | 2000-11-06 | 工業技術院長 | Fgf−5の生理的機能制御ペプチド及び該ペプチドを含有する医薬組成物 |
| US7090973B1 (en) * | 1999-04-09 | 2006-08-15 | Oscient Pharmaceuticals Corporation | Nucleic acid sequences relating to Bacteroides fragilis for diagnostics and therapeutics |
| US20040031072A1 (en) * | 1999-05-06 | 2004-02-12 | La Rosa Thomas J. | Soy nucleic acid molecules and other molecules associated with transcription plants and uses thereof for plant improvement |
| US20100293669A2 (en) * | 1999-05-06 | 2010-11-18 | Jingdong Liu | Nucleic Acid Molecules and Other Molecules Associated with Plants and Uses Thereof for Plant Improvement |
| US6872563B1 (en) * | 1999-10-05 | 2005-03-29 | President And Fellows Of Harvard College | Compositions and methods for production of disulfide bond containing proteins in host cells |
| AU5056501A (en) * | 2000-03-31 | 2001-10-08 | Nobuyuki Itoh | Fibroblast growth factor-like molecules and uses thereof |
| PT1360500E (pt) * | 2000-04-14 | 2010-04-19 | Genencor Int | Métodos para direccionamento selectivo |
| US20110131679A2 (en) * | 2000-04-19 | 2011-06-02 | Thomas La Rosa | Rice Nucleic Acid Molecules and Other Molecules Associated with Plants and Uses Thereof for Plant Improvement |
| AU2001271589A1 (en) * | 2000-06-30 | 2002-01-14 | Zymogenetics Inc. | Mammalian secreted proteins |
| US6537968B1 (en) * | 2000-07-24 | 2003-03-25 | Alphamed Pharmaceuticals Corp | Treatment of lupus erythematosus |
| CA2430953A1 (en) * | 2000-12-13 | 2002-06-20 | Borean Pharma A/S | Combinatorial libraries of proteins having the scaffold structure of c-type lectin-like domains |
| US7214786B2 (en) * | 2000-12-14 | 2007-05-08 | Kovalic David K | Nucleic acid molecules and other molecules associated with plants and uses thereof for plant improvement |
| US20070020625A1 (en) * | 2001-02-07 | 2007-01-25 | Eric Duchaud | Sequence of the photorhabdus luminescens strain tt01 genome and uses |
| WO2004072223A2 (en) * | 2003-02-11 | 2004-08-26 | Institut Pasteur | Identification and characterization of racemases, definition of protein signatures, and a test for detecting d-amino acid and for screening molecules capable of inhibiting the activity of racemase, especially proline racemase |
| ATE555119T1 (de) * | 2003-11-06 | 2012-05-15 | Danisco Us Inc | Expression von proteaseinhibitoren und varianten davon in filamentösen pilzen |
| DK1680507T3 (da) * | 2003-11-06 | 2011-10-10 | Danisco Us Inc | Bakterieekspression af proteaseinhibitorer og varianter deraf |
| US7319142B1 (en) * | 2004-08-31 | 2008-01-15 | Monsanto Technology Llc | Nucleotide and amino acid sequences from Xenorhabdus and uses thereof |
| US7803902B2 (en) * | 2008-10-15 | 2010-09-28 | Danisco Us Inc. | Modified variant bowman birk protease inhibitors |
| US7772181B2 (en) * | 2008-10-15 | 2010-08-10 | Danisco Us Inc. | Personal care compositions comprising modified variant Bowman Birk Protease Inhibitors |
-
2004
- 2004-11-06 DK DK04800809.8T patent/DK1680507T3/da active
- 2004-11-06 AT AT04818640T patent/ATE486087T1/de not_active IP Right Cessation
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- 2004-11-06 JP JP2006539676A patent/JP4843497B2/ja not_active Expired - Fee Related
- 2004-11-06 WO PCT/US2004/036976 patent/WO2005046709A2/en not_active Ceased
- 2004-11-06 EP EP04818640A patent/EP1692160B1/de not_active Expired - Lifetime
- 2004-11-06 US US10/581,142 patent/US20080113917A1/en not_active Abandoned
- 2004-11-06 EP EP04810432A patent/EP1692159B1/de not_active Expired - Lifetime
- 2004-11-06 WO PCT/US2004/036979 patent/WO2005046710A2/en not_active Ceased
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- 2004-11-06 DE DE602004029393T patent/DE602004029393D1/de not_active Expired - Lifetime
- 2004-11-06 EP EP04810431A patent/EP1692158B1/de not_active Expired - Lifetime
- 2004-11-06 DE DE602004029812T patent/DE602004029812D1/de not_active Expired - Lifetime
- 2004-11-06 DK DK04810431.9T patent/DK1692158T3/da active
- 2004-11-06 EP EP04800809A patent/EP1680507B1/de not_active Expired - Lifetime
- 2004-11-06 WO PCT/US2004/036980 patent/WO2005047314A2/en not_active Ceased
- 2004-11-06 WO PCT/US2004/036981 patent/WO2005047511A2/en not_active Ceased
- 2004-11-06 ES ES04810431T patent/ES2375360T3/es not_active Expired - Lifetime
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- 2004-11-08 US US10/984,270 patent/US7524816B2/en not_active Expired - Fee Related
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- 2004-11-08 US US10/984,514 patent/US7413877B2/en not_active Expired - Lifetime
-
2008
- 2008-02-19 US US12/033,848 patent/US20080269139A1/en not_active Abandoned
- 2008-07-14 US US12/172,921 patent/US7696173B2/en active Active
-
2009
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