DE60129829T2 - Zyklisierte benzamid-neurokinin-antagonisten zur verwendung in der therapie - Google Patents
Zyklisierte benzamid-neurokinin-antagonisten zur verwendung in der therapie Download PDFInfo
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- DE60129829T2 DE60129829T2 DE60129829T DE60129829T DE60129829T2 DE 60129829 T2 DE60129829 T2 DE 60129829T2 DE 60129829 T DE60129829 T DE 60129829T DE 60129829 T DE60129829 T DE 60129829T DE 60129829 T2 DE60129829 T2 DE 60129829T2
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- Prior art keywords
- alkyl
- cyano
- compound according
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- alkylcarbamoyl
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Classifications
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Landscapes
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- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Hydrogenated Pyridines (AREA)
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| SE0003476 | 2000-09-28 | ||
| SE0003476A SE0003476D0 (sv) | 2000-09-28 | 2000-09-28 | Compounds |
| PCT/SE2001/002100 WO2002026724A1 (en) | 2000-09-28 | 2001-09-27 | Cyclized benzamide neurokinin antagonists for use in therapy |
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| DE60129829D1 DE60129829D1 (de) | 2007-09-20 |
| DE60129829T2 true DE60129829T2 (de) | 2008-04-30 |
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| DE60129829T Expired - Fee Related DE60129829T2 (de) | 2000-09-28 | 2001-09-27 | Zyklisierte benzamid-neurokinin-antagonisten zur verwendung in der therapie |
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| Country | Link |
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| US (2) | US6924277B2 (enExample) |
| EP (1) | EP1324992B1 (enExample) |
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| AU (1) | AU2001290480A1 (enExample) |
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| ES (1) | ES2288988T3 (enExample) |
| SE (1) | SE0003476D0 (enExample) |
| WO (1) | WO2002026724A1 (enExample) |
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| US20060030556A1 (en) * | 2004-08-04 | 2006-02-09 | Solvay Pharmaceuticals B.V. | Neurokinin-1 receptor antagonists for the treatment of conditions responsive to testosterone elevation, including testosterone deficiency |
| WO2006013205A1 (en) * | 2004-08-04 | 2006-02-09 | Solvay Pharmaceuticals B.V. | Neurokinin-1 receptor antagonists for the treatment of conditions responsive to testosterone elevation |
| DE102004038134B4 (de) | 2004-08-05 | 2013-07-25 | Johann Wolfgang Goethe-Universität Frankfurt am Main | Multivalente Chelatoren zum Modifizieren und Organisieren von Zielmolekülen, Verfahren zu ihrer Herstellung sowie ihre Verwendung |
| US20060030600A1 (en) * | 2004-08-06 | 2006-02-09 | Patrick Schnider | Dual NK1/NK3 receptor antagonists for the treatment of schizophrenia |
| EP1976495A2 (en) * | 2006-01-06 | 2008-10-08 | Aarhus Universitet | Compounds acting on the serotonin transporter |
| WO2008090114A1 (en) | 2007-01-24 | 2008-07-31 | Glaxo Group Limited | Pharmaceutical compositions comprising 2-methoxy-5- (5-trifluoromethyl-tetrazol-i-yl-benzyl) - (2s-phenyl-piperidin-3s-yl-) |
| WO2012061754A2 (en) * | 2010-11-05 | 2012-05-10 | The Broad Institute, Inc. | Compounds and methods for treating autoimmune diseases |
| EP2691391A4 (en) * | 2011-03-29 | 2014-09-10 | Broad Inst Inc | COMPOUNDS AND METHODS OF TREATING DISORDERS MEDIATED BY ISOCITRATE DEHYDROGENASE |
| EP2729147B1 (en) | 2011-07-04 | 2017-09-06 | IRBM - Science Park S.p.A. | Nk-1 receptor antagonists for treating corneal neovascularisation |
| TWI598325B (zh) * | 2012-10-12 | 2017-09-11 | Ｈ 朗德貝克公司 | 苯甲醯胺類 |
| TW201427947A (zh) | 2012-10-12 | 2014-07-16 | Lundbeck & Co As H | 環狀胺 |
| WO2019162519A1 (en) | 2018-02-26 | 2019-08-29 | Ospedale San Raffaele S.R.L. | Nk-1 antagonists for use in the treatment of ocular pain |
| RU2697414C1 (ru) | 2018-05-11 | 2019-08-14 | Общество с ограниченной ответственностью "АЙ БИ ДИ Терапевтикс" | Новый антагонист тахикининовых рецепторов и его применение |
| KR20210061377A (ko) | 2018-09-18 | 2021-05-27 | 테른스, 인크. | 특정 백혈병을 치료하기 위한 화합물 |
| US20230134843A1 (en) | 2020-03-11 | 2023-05-04 | Ospedale San Raffaele S.R.L. | Treatment of stem cell deficiency |
| CN118139849A (zh) * | 2021-09-30 | 2024-06-04 | 江苏豪森药业集团有限公司 | 四元稠环类化合物及其制备方法和应用 |
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| JP2935541B2 (ja) * | 1990-06-28 | 1999-08-16 | サントリー株式会社 | 縮合複素環化合物 |
| US5525600A (en) | 1994-11-28 | 1996-06-11 | American Home Products Corporation | (Thiophen-2-yl)-piperidin or tetrahydropyridin carboxamides |
| GB9505084D0 (en) | 1995-03-14 | 1995-05-03 | Pfizer Ltd | Benzamide derivative |
| US5541179A (en) | 1995-05-02 | 1996-07-30 | American Home Products Corporation | Tropon-2-one piperazine carboxamides as serotonergic agents |
| US5998439A (en) | 1996-02-21 | 1999-12-07 | Hoescht Marion Roussel, Inc. | Substituted N-methyl-N-(4-(piperidin-1-yl)-2-(aryl)butyl)benzamides useful for the treatment of allergic diseases |
| US5789422A (en) * | 1996-10-28 | 1998-08-04 | Schering Corporation | Substituted arylalkylamines as neurokinin antagonists |
| GB9922521D0 (en) * | 1998-10-07 | 1999-11-24 | Zeneca Ltd | Compounds |
| FR2792835B3 (fr) | 1999-04-27 | 2001-05-25 | Sanofi Sa | Utilisation du saredutant pour la preparation de medicaments utiles dans le traitement ou la prevention de l'ensemble des troubles de l'humeur, des troubles de l'adaptation ou des troubles mixtes anxiete-depression |
| ATE400563T1 (de) * | 2000-04-06 | 2008-07-15 | Astrazeneca Ab | Neue neurokinin-antagonisten zum gebrauch als arzneimittel |
-
2000
- 2000-09-28 SE SE0003476A patent/SE0003476D0/xx unknown
-
2001
- 2001-09-27 US US10/381,755 patent/US6924277B2/en not_active Expired - Fee Related
- 2001-09-27 AT AT01970480T patent/ATE369348T1/de not_active IP Right Cessation
- 2001-09-27 JP JP2002531108A patent/JP2004509954A/ja active Pending
- 2001-09-27 DE DE60129829T patent/DE60129829T2/de not_active Expired - Fee Related
- 2001-09-27 EP EP01970480A patent/EP1324992B1/en not_active Expired - Lifetime
- 2001-09-27 WO PCT/SE2001/002100 patent/WO2002026724A1/en not_active Ceased
- 2001-09-27 ES ES01970480T patent/ES2288988T3/es not_active Expired - Lifetime
- 2001-09-27 AU AU2001290480A patent/AU2001290480A1/en not_active Abandoned
-
2005
- 2005-04-27 US US11/115,572 patent/US20050192318A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| JP2004509954A (ja) | 2004-04-02 |
| EP1324992A1 (en) | 2003-07-09 |
| US20040029850A1 (en) | 2004-02-12 |
| ES2288988T3 (es) | 2008-02-01 |
| AU2001290480A1 (en) | 2002-04-08 |
| ATE369348T1 (de) | 2007-08-15 |
| US20050192318A1 (en) | 2005-09-01 |
| EP1324992B1 (en) | 2007-08-08 |
| US6924277B2 (en) | 2005-08-02 |
| SE0003476D0 (sv) | 2000-09-28 |
| WO2002026724A1 (en) | 2002-04-04 |
| DE60129829D1 (de) | 2007-09-20 |
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