DE60033825T2 - Detektion von unterschieden in nukleinsäuren durch inhibierung spontaner dna verzweigungsmigration - Google Patents

Detektion von unterschieden in nukleinsäuren durch inhibierung spontaner dna verzweigungsmigration Download PDF

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Publication number
DE60033825T2
DE60033825T2 DE60033825T DE60033825T DE60033825T2 DE 60033825 T2 DE60033825 T2 DE 60033825T2 DE 60033825 T DE60033825 T DE 60033825T DE 60033825 T DE60033825 T DE 60033825T DE 60033825 T2 DE60033825 T2 DE 60033825T2
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Prior art keywords
primer
sequence
target
nucleic acid
hybridization
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Expired - Lifetime
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DE60033825T
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German (de)
English (en)
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DE60033825D1 (de
Inventor
Alla San Jose LISHANSKI
Marc Mountain View TAYLOR
Nurith Palo Alto KURN
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Siemens Healthcare Diagnostics Inc
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Dade Behring Inc
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6839—Triple helix formation or other higher order conformations in hybridisation assays
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6858—Allele-specific amplification

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DE60033825T 1999-08-17 2000-08-15 Detektion von unterschieden in nukleinsäuren durch inhibierung spontaner dna verzweigungsmigration Expired - Lifetime DE60033825T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/376,097 US6232104B1 (en) 1999-08-17 1999-08-17 Detection of differences in nucleic acids by inhibition of spontaneous DNA branch migration
US376097 1999-08-17
PCT/US2000/022446 WO2001012859A2 (en) 1999-08-17 2000-08-15 Detection of differences in nucleic acids by inhibition of spontaneous dna branch migration

Publications (2)

Publication Number Publication Date
DE60033825D1 DE60033825D1 (de) 2007-04-19
DE60033825T2 true DE60033825T2 (de) 2007-11-08

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Family Applications (1)

Application Number Title Priority Date Filing Date
DE60033825T Expired - Lifetime DE60033825T2 (de) 1999-08-17 2000-08-15 Detektion von unterschieden in nukleinsäuren durch inhibierung spontaner dna verzweigungsmigration

Country Status (6)

Country Link
US (1) US6232104B1 (enExample)
EP (1) EP1210457B1 (enExample)
JP (1) JP2003507025A (enExample)
DE (1) DE60033825T2 (enExample)
ES (1) ES2281354T3 (enExample)
WO (1) WO2001012859A2 (enExample)

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US9957549B2 (en) 2012-06-18 2018-05-01 Nugen Technologies, Inc. Compositions and methods for negative selection of non-desired nucleic acid sequences
US20150011396A1 (en) 2012-07-09 2015-01-08 Benjamin G. Schroeder Methods for creating directional bisulfite-converted nucleic acid libraries for next generation sequencing
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CN105849264B (zh) 2013-11-13 2019-09-27 纽亘技术公司 用于鉴别重复测序读数的组合物和方法
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EP3287528A1 (de) 2016-08-25 2018-02-28 AGCT GmbH Verfahren zur amplifikation von nukleinsäuren und kit zu dessen durchführung
JP6997772B2 (ja) 2016-09-15 2022-01-18 アーチャーディーエックス， エルエルシー 核酸サンプル調製の方法
EP4353830A3 (en) 2016-09-15 2024-07-03 ArcherDX, LLC Methods of nucleic acid sample preparation for analysis of cell-free dna
US12492430B2 (en) 2017-04-11 2025-12-09 Tecan Genomics, Inc. Library quantitation and qualification
US11099202B2 (en) 2017-10-20 2021-08-24 Tecan Genomics, Inc. Reagent delivery system
AU2020218190A1 (en) * 2019-02-04 2021-08-26 Akoya Biosciences, Inc. Analyte detection by selective labeling of biological samples
US12059674B2 (en) 2020-02-03 2024-08-13 Tecan Genomics, Inc. Reagent storage system

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Also Published As

Publication number Publication date
WO2001012859A2 (en) 2001-02-22
US6232104B1 (en) 2001-05-15
EP1210457A2 (en) 2002-06-05
JP2003507025A (ja) 2003-02-25
ES2281354T3 (es) 2007-10-01
DE60033825D1 (de) 2007-04-19
WO2001012859A3 (en) 2002-01-31
EP1210457B1 (en) 2007-03-07

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: SIEMENS HEALTHCARE DIAGNOSTICS INC., DEERFIELD, US

8328 Change in the person/name/address of the agent

Representative=s name: PLATE SCHWEITZER ZOUNEK PATENTANWAELTE, 65203 WIES