DE60033825D1 - Detektion von unterschieden in nukleinsäuren durch inhibierung spontaner dna verzweigungsmigration - Google Patents

Detektion von unterschieden in nukleinsäuren durch inhibierung spontaner dna verzweigungsmigration

Info

Publication number
DE60033825D1
DE60033825D1 DE60033825T DE60033825T DE60033825D1 DE 60033825 D1 DE60033825 D1 DE 60033825D1 DE 60033825 T DE60033825 T DE 60033825T DE 60033825 T DE60033825 T DE 60033825T DE 60033825 D1 DE60033825 D1 DE 60033825D1
Authority
DE
Germany
Prior art keywords
inhibition
differences
detection
nucleic acids
spontaneous dna
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60033825T
Other languages
English (en)
Other versions
DE60033825T2 (de
Inventor
Alla Lishanski
Marc Taylor
Nurith Kurn
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Siemens Healthcare Diagnostics Inc
Original Assignee
Dade Behring Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dade Behring Inc filed Critical Dade Behring Inc
Publication of DE60033825D1 publication Critical patent/DE60033825D1/de
Application granted granted Critical
Publication of DE60033825T2 publication Critical patent/DE60033825T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6839—Triple helix formation or other higher order conformations in hybridisation assays
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6858—Allele-specific amplification

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DE60033825T 1999-08-17 2000-08-15 Detektion von unterschieden in nukleinsäuren durch inhibierung spontaner dna verzweigungsmigration Expired - Lifetime DE60033825T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/376,097 US6232104B1 (en) 1999-08-17 1999-08-17 Detection of differences in nucleic acids by inhibition of spontaneous DNA branch migration
US376097 1999-08-17
PCT/US2000/022446 WO2001012859A2 (en) 1999-08-17 2000-08-15 Detection of differences in nucleic acids by inhibition of spontaneous dna branch migration

Publications (2)

Publication Number Publication Date
DE60033825D1 true DE60033825D1 (de) 2007-04-19
DE60033825T2 DE60033825T2 (de) 2007-11-08

Family

ID=23483699

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60033825T Expired - Lifetime DE60033825T2 (de) 1999-08-17 2000-08-15 Detektion von unterschieden in nukleinsäuren durch inhibierung spontaner dna verzweigungsmigration

Country Status (6)

Country Link
US (1) US6232104B1 (de)
EP (1) EP1210457B1 (de)
JP (1) JP2003507025A (de)
DE (1) DE60033825T2 (de)
ES (1) ES2281354T3 (de)
WO (1) WO2001012859A2 (de)

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US6878530B2 (en) * 2002-02-07 2005-04-12 Panomics, Inc. Methods for detecting polymorphisms in nucleic acids
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US7273762B2 (en) 2004-11-09 2007-09-25 Freescale Semiconductor, Inc. Microelectromechanical (MEM) device including a spring release bridge and method of making the same
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ES2905448T3 (es) 2012-05-10 2022-04-08 Massachusetts Gen Hospital Métodos para determinar una secuencia nucleotídica
GB2518078B (en) 2012-06-18 2015-04-29 Nugen Technologies Inc Compositions and methods for negative selection of non-desired nucleic acid sequences
US20150011396A1 (en) 2012-07-09 2015-01-08 Benjamin G. Schroeder Methods for creating directional bisulfite-converted nucleic acid libraries for next generation sequencing
EP2738263A1 (de) * 2012-11-30 2014-06-04 Fundacion para la Investigacion del Hospital Clinico de la Comunidad Valenciana Verfahren zur Analyse von DNA-Umbauten
US9822408B2 (en) 2013-03-15 2017-11-21 Nugen Technologies, Inc. Sequential sequencing
EP3068883B1 (de) 2013-11-13 2020-04-29 Nugen Technologies, Inc. Zusammensetzungen und verfahren zur identifizierung einer duplikatsequenzierungslesung
EP4219744A3 (de) 2014-01-27 2023-08-30 The General Hospital Corporation Verfahren zur herstellung von nukleinsäuren zur sequenzierung
US9745614B2 (en) 2014-02-28 2017-08-29 Nugen Technologies, Inc. Reduced representation bisulfite sequencing with diversity adaptors
EP3287528A1 (de) 2016-08-25 2018-02-28 AGCT GmbH Verfahren zur amplifikation von nukleinsäuren und kit zu dessen durchführung
EP3512965B1 (de) 2016-09-15 2024-03-13 ArcherDX, LLC Verfahren zur herstellung von nukleinsäuren zur analyse von zellfreier dna
EP3512947B1 (de) 2016-09-15 2021-10-20 ArcherDX, LLC Verfahren für die zubereitung von nukleinsäureproben
US11099202B2 (en) 2017-10-20 2021-08-24 Tecan Genomics, Inc. Reagent delivery system
CN113614244A (zh) * 2019-02-04 2021-11-05 阿科亚生物科学股份有限公司 通过选择性标记生物样品进行分析物检测
US12059674B2 (en) 2020-02-03 2024-08-13 Tecan Genomics, Inc. Reagent storage system

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JP2650159B2 (ja) 1988-02-24 1997-09-03 アクゾ・ノベル・エヌ・ベー 核酸増幅方法
US5622820A (en) 1988-03-10 1997-04-22 City Of Hope Method for amplification and detection of RNA and DNA sequences
JP2939485B2 (ja) 1988-09-08 1999-08-25 ザ・ソーク・インスチュート・フォーバイオロジカル・スタディーズ 複製ｒｎａに基づく増幅／検出系
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US5556750A (en) 1989-05-12 1996-09-17 Duke University Methods and kits for fractionating a population of DNA molecules based on the presence or absence of a base-pair mismatch utilizing mismatch repair systems
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US5595891A (en) 1990-07-19 1997-01-21 Behringwerke Ag Method for producing a polynucleotide for use in single primer amplification
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DK0519338T3 (da) * 1991-06-20 1996-10-28 Hoffmann La Roche Forbedrede fremgangsmåder til nukleinsyreamplifikation
US5582981A (en) 1991-08-14 1996-12-10 Gilead Sciences, Inc. Method for identifying an oligonucleotide aptamer specific for a target
CA2077135A1 (en) 1991-08-30 1993-03-01 Joh-E Ikeda A method of dna amplification
DE4213029A1 (de) 1991-09-26 1993-04-01 Boehringer Mannheim Gmbh Verfahren zur spezifischen vervielfaeltigung von nukleins aeuresequenzen
EP0567635B1 (de) 1991-11-15 2000-05-31 Igen International, Inc. Schnelle bestimmungsverfahren für amplifikationsprodukte
US5567583A (en) 1991-12-16 1996-10-22 Biotronics Corporation Methods for reducing non-specific priming in DNA detection
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US5340728A (en) 1992-12-09 1994-08-23 E. I. Du Pont De Nemours And Company Method for amplification of targeted segments of nucleic acid using nested polymerase chain reaction
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AU7551594A (en) 1993-07-29 1995-02-28 MURASHIGE, Kate H. Method for recognition of the nucleotide sequence of a purified dna segment
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Also Published As

Publication number Publication date
US6232104B1 (en) 2001-05-15
ES2281354T3 (es) 2007-10-01
WO2001012859A3 (en) 2002-01-31
JP2003507025A (ja) 2003-02-25
EP1210457B1 (de) 2007-03-07
WO2001012859A2 (en) 2001-02-22
EP1210457A2 (de) 2002-06-05
DE60033825T2 (de) 2007-11-08

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: SIEMENS HEALTHCARE DIAGNOSTICS INC., DEERFIELD, US

8328 Change in the person/name/address of the agent

Representative=s name: PLATE SCHWEITZER ZOUNEK PATENTANWAELTE, 65203 WIES