DE60029446T2 - Arylthiazolidindione und aryloxazolidindion-derivate - Google Patents

Arylthiazolidindione und aryloxazolidindion-derivate Download PDF

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Publication number
DE60029446T2
DE60029446T2 DE60029446T DE60029446T DE60029446T2 DE 60029446 T2 DE60029446 T2 DE 60029446T2 DE 60029446 T DE60029446 T DE 60029446T DE 60029446 T DE60029446 T DE 60029446T DE 60029446 T2 DE60029446 T2 DE 60029446T2
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DE
Germany
Prior art keywords
propyl
thiazolidinedione
phenyl
methyl
propoxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60029446T
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German (de)
English (en)
Other versions
DE60029446D1 (de
Inventor
P. Soumya Rahway SAHOO
Conrad Rahway SANTINI
K. Julia Rahway BOUERES
V. James Rahway HECK
Edward Rahway METZGER
K. Victoria Rahway LOMBARDO
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of DE60029446D1 publication Critical patent/DE60029446D1/de
Application granted granted Critical
Publication of DE60029446T2 publication Critical patent/DE60029446T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/34—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Obesity (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
DE60029446T 1999-06-18 2000-06-16 Arylthiazolidindione und aryloxazolidindion-derivate Expired - Fee Related DE60029446T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13995399P 1999-06-18 1999-06-18
US139953P 1999-06-18
PCT/US2000/016586 WO2000078312A1 (en) 1999-06-18 2000-06-16 Arylthiazolidinedione and aryloxazolidinedione derivatives

Publications (2)

Publication Number Publication Date
DE60029446D1 DE60029446D1 (de) 2006-08-31
DE60029446T2 true DE60029446T2 (de) 2007-02-08

Family

ID=22489062

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60029446T Expired - Fee Related DE60029446T2 (de) 1999-06-18 2000-06-16 Arylthiazolidindione und aryloxazolidindion-derivate

Country Status (9)

Country Link
US (1) US6399640B1 (enExample)
EP (1) EP1194146B1 (enExample)
JP (1) JP2003502369A (enExample)
AT (1) ATE333448T1 (enExample)
AU (1) AU773505B2 (enExample)
CA (1) CA2376919C (enExample)
DE (1) DE60029446T2 (enExample)
ES (1) ES2265952T3 (enExample)
WO (1) WO2000078312A1 (enExample)

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ES2274013T3 (es) 2001-01-26 2007-05-16 Schering Corporation Combinaciones de activador(es) del receptor activado por el proliferador de los peroxisomas (ppar) e inhibidor(es)m de la absorcion de estelores y tratamientos para trastornos vasculares.
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Also Published As

Publication number Publication date
CA2376919C (en) 2008-11-04
US6399640B1 (en) 2002-06-04
AU773505B2 (en) 2004-05-27
EP1194146A1 (en) 2002-04-10
DE60029446D1 (de) 2006-08-31
WO2000078312A1 (en) 2000-12-28
EP1194146A4 (en) 2002-07-31
CA2376919A1 (en) 2000-12-28
EP1194146B1 (en) 2006-07-19
AU5875500A (en) 2001-01-09
ES2265952T3 (es) 2007-03-01
ATE333448T1 (de) 2006-08-15
JP2003502369A (ja) 2003-01-21

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