DE3629052C2 - Antitumor-Antibiotika - Google Patents

Antitumor-Antibiotika

Info

Publication number
DE3629052C2
DE3629052C2 DE3629052A DE3629052A DE3629052C2 DE 3629052 C2 DE3629052 C2 DE 3629052C2 DE 3629052 A DE3629052 A DE 3629052A DE 3629052 A DE3629052 A DE 3629052A DE 3629052 C2 DE3629052 C2 DE 3629052C2
Authority
DE
Germany
Prior art keywords
bbm
vol
shows
methanol
spectrum
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE3629052A
Other languages
German (de)
English (en)
Other versions
DE3629052A1 (de
Inventor
Jerzey Golik
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Squibb Co
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of DE3629052A1 publication Critical patent/DE3629052A1/de
Application granted granted Critical
Publication of DE3629052C2 publication Critical patent/DE3629052C2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02Acyclic radicals, not substituted by cyclic structures
    • C07H15/14Acyclic radicals, not substituted by cyclic structures attached to a sulfur, selenium or tellurium atom of a saccharide radical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H11/00Compounds containing saccharide radicals esterified by inorganic acids; Metal salts thereof
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C12P1/06Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using actinomycetales
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/03Actinomadura

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)
DE3629052A 1985-08-27 1986-08-27 Antitumor-Antibiotika Expired - Fee Related DE3629052C2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US77033585A 1985-08-27 1985-08-27

Publications (2)

Publication Number Publication Date
DE3629052A1 DE3629052A1 (de) 1987-05-07
DE3629052C2 true DE3629052C2 (de) 1995-09-28

Family

ID=25088206

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3629052A Expired - Fee Related DE3629052C2 (de) 1985-08-27 1986-08-27 Antitumor-Antibiotika

Country Status (26)

Country Link
JP (2) JPH0733393B2 (el)
KR (1) KR920010226B1 (el)
AT (1) AT392971B (el)
AU (1) AU604464B2 (el)
BE (1) BE905332A (el)
CA (1) CA1307256C (el)
CH (1) CH668598A5 (el)
CY (1) CY1676A (el)
DE (1) DE3629052C2 (el)
DK (1) DK170671B1 (el)
ES (1) ES2002728A6 (el)
FI (1) FI83422C (el)
FR (1) FR2586686B1 (el)
GB (1) GB2179649A (el)
GR (1) GR862160B (el)
HK (1) HK793A (el)
HU (1) HU197915B (el)
IE (1) IE59204B1 (el)
IL (1) IL79519A0 (el)
IT (1) IT1229176B (el)
LU (1) LU86562A1 (el)
NL (1) NL8602165A (el)
PT (1) PT83261B (el)
SE (2) SE469632B (el)
SG (1) SG109692G (el)
ZA (1) ZA865796B (el)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE219096T1 (de) * 1987-01-30 2002-06-15 American Cyanamid Co Dihydroderivate der antibiotika vom typ ll-e33288
US4916065A (en) * 1988-06-10 1990-04-10 Bristol-Myers Company BU-3420T Antitumor antibiotic
US5086045A (en) * 1989-03-15 1992-02-04 Bristol-Myers Squibb Company Antitumor antibiotic
US5028536A (en) * 1989-03-15 1991-07-02 Bristol-Myers Squibb Company Antitumor antibiotic BMY-41339
CA2027601A1 (en) * 1989-11-06 1991-05-07 Koko Sugawara Antitumor antibiotic bu-3983t
CA2039789A1 (en) * 1990-04-27 1991-10-28 Samuel J. Danishefsky Calicheamicinone, derivatives and analogs thereof and methods of making the same
US5116845A (en) * 1990-05-04 1992-05-26 Bristol-Myers Company BU-3420T antitumor antibiotic
US5264586A (en) * 1991-07-17 1993-11-23 The Scripps Research Institute Analogs of calicheamicin gamma1I, method of making and using the same

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3148023A1 (de) * 1981-12-04 1983-06-09 Rudolf Dipl.-Ing. 8901 Oberottmarshausen Fischer Heizungskessel fuer heisse rauchgase
US4578271A (en) * 1982-05-24 1986-03-25 Fujisawa Pharmaceutical Co., Ltd. Biologically active WS 6049 substances, a process for the production thereof and their pharmaceutical compositions
NZ208013A (en) * 1983-05-16 1987-07-31 Bristol Myers Co Antitumour antibiotic bbm-1675 and production by cultivating actinomadura verrucosospora
JPS606194A (ja) * 1983-06-23 1985-01-12 Meiji Seika Kaisha Ltd 新規抗生物質sf−2288及びその製造法
US4530835A (en) * 1983-07-08 1985-07-23 Warner-Lambert Company CL-1577 Antibiotic compounds and their production

Also Published As

Publication number Publication date
ATA231786A (de) 1990-12-15
CH668598A5 (de) 1989-01-13
FR2586686A1 (fr) 1987-03-06
GR862160B (en) 1986-12-31
IL79519A0 (en) 1986-10-31
LU86562A1 (fr) 1987-03-06
CA1307256C (en) 1992-09-08
AU6175186A (en) 1987-03-05
FI83422C (fi) 1991-07-10
PT83261A (en) 1986-09-01
KR920010226B1 (ko) 1992-11-21
HU197915B (en) 1989-06-28
DK406086A (da) 1987-02-28
GB2179649A (en) 1987-03-11
CY1676A (en) 1993-10-10
SE8603597L (sv) 1987-02-28
KR870002269A (ko) 1987-03-30
SG109692G (en) 1992-12-24
JPH07233186A (ja) 1995-09-05
GB8620118D0 (en) 1986-10-01
IE862280L (en) 1987-02-27
HUT44035A (en) 1988-01-28
AU604464B2 (en) 1990-12-20
ZA865796B (en) 1987-04-29
JPS62116589A (ja) 1987-05-28
PT83261B (pt) 1989-05-12
BE905332A (fr) 1987-02-26
FI863405A (fi) 1987-02-28
DK170671B1 (da) 1995-11-27
ES2002728A6 (es) 1988-10-01
SE9200428D0 (sv) 1992-02-13
FR2586686B1 (fr) 1990-02-02
HK793A (en) 1993-01-15
IE59204B1 (en) 1994-01-26
DK406086D0 (da) 1986-08-26
JPH0733393B2 (ja) 1995-04-12
DE3629052A1 (de) 1987-05-07
SE8603597D0 (sv) 1986-08-26
FI863405A0 (fi) 1986-08-22
IT8621527A0 (it) 1986-08-26
FI83422B (fi) 1991-03-28
NL8602165A (nl) 1987-03-16
AT392971B (de) 1991-07-25
SE469632B (sv) 1993-08-09
SE9200428L (sv) 1993-08-14
GB2179649B (el) 1989-10-25
IT1229176B (it) 1991-07-23

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Legal Events

Date Code Title Description
8127 New person/name/address of the applicant

Owner name: BRISTOL-MYERS SQUIBB CO. (N.D.GES.D.STAATES DELAWA

8110 Request for examination paragraph 44
D2 Grant after examination
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee