CA1307256C - Bbm-1675c and d antitumor antibiotics - Google Patents

Bbm-1675c and d antitumor antibiotics

Info

Publication number
CA1307256C
CA1307256C CA000516111A CA516111A CA1307256C CA 1307256 C CA1307256 C CA 1307256C CA 000516111 A CA000516111 A CA 000516111A CA 516111 A CA516111 A CA 516111A CA 1307256 C CA1307256 C CA 1307256C
Authority
CA
Canada
Prior art keywords
bbm
follows
exhibiting
methanol
spectrum
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA000516111A
Other languages
English (en)
French (fr)
Inventor
Jerzy Golik
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Squibb Co
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Application granted granted Critical
Publication of CA1307256C publication Critical patent/CA1307256C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02Acyclic radicals, not substituted by cyclic structures
    • C07H15/14Acyclic radicals, not substituted by cyclic structures attached to a sulfur, selenium or tellurium atom of a saccharide radical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H11/00Compounds containing saccharide radicals esterified by inorganic acids; Metal salts thereof
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C12P1/06Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using actinomycetales
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/03Actinomadura

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Mycology (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)
CA000516111A 1985-08-27 1986-08-15 Bbm-1675c and d antitumor antibiotics Expired - Fee Related CA1307256C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US77033585A 1985-08-27 1985-08-27
US770,335 1985-08-27

Publications (1)

Publication Number Publication Date
CA1307256C true CA1307256C (en) 1992-09-08

Family

ID=25088206

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000516111A Expired - Fee Related CA1307256C (en) 1985-08-27 1986-08-15 Bbm-1675c and d antitumor antibiotics

Country Status (26)

Country Link
JP (2) JPH0733393B2 (el)
KR (1) KR920010226B1 (el)
AT (1) AT392971B (el)
AU (1) AU604464B2 (el)
BE (1) BE905332A (el)
CA (1) CA1307256C (el)
CH (1) CH668598A5 (el)
CY (1) CY1676A (el)
DE (1) DE3629052C2 (el)
DK (1) DK170671B1 (el)
ES (1) ES2002728A6 (el)
FI (1) FI83422C (el)
FR (1) FR2586686B1 (el)
GB (1) GB2179649A (el)
GR (1) GR862160B (el)
HK (1) HK793A (el)
HU (1) HU197915B (el)
IE (1) IE59204B1 (el)
IL (1) IL79519A0 (el)
IT (1) IT1229176B (el)
LU (1) LU86562A1 (el)
NL (1) NL8602165A (el)
PT (1) PT83261B (el)
SE (2) SE469632B (el)
SG (1) SG109692G (el)
ZA (1) ZA865796B (el)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2177518T3 (es) * 1987-01-30 2002-12-16 American Cyanamid Co Derivados dihidro de los antibioticos ll-e33288.
US4916065A (en) * 1988-06-10 1990-04-10 Bristol-Myers Company BU-3420T Antitumor antibiotic
US5028536A (en) * 1989-03-15 1991-07-02 Bristol-Myers Squibb Company Antitumor antibiotic BMY-41339
US5086045A (en) * 1989-03-15 1992-02-04 Bristol-Myers Squibb Company Antitumor antibiotic
CA2027601A1 (en) * 1989-11-06 1991-05-07 Koko Sugawara Antitumor antibiotic bu-3983t
CA2039789A1 (en) * 1990-04-27 1991-10-28 Samuel J. Danishefsky Calicheamicinone, derivatives and analogs thereof and methods of making the same
US5116845A (en) * 1990-05-04 1992-05-26 Bristol-Myers Company BU-3420T antitumor antibiotic
US5264586A (en) * 1991-07-17 1993-11-23 The Scripps Research Institute Analogs of calicheamicin gamma1I, method of making and using the same

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3148023A1 (de) * 1981-12-04 1983-06-09 Rudolf Dipl.-Ing. 8901 Oberottmarshausen Fischer Heizungskessel fuer heisse rauchgase
US4578271A (en) * 1982-05-24 1986-03-25 Fujisawa Pharmaceutical Co., Ltd. Biologically active WS 6049 substances, a process for the production thereof and their pharmaceutical compositions
NZ208013A (en) * 1983-05-16 1987-07-31 Bristol Myers Co Antitumour antibiotic bbm-1675 and production by cultivating actinomadura verrucosospora
JPS606194A (ja) * 1983-06-23 1985-01-12 Meiji Seika Kaisha Ltd 新規抗生物質sf−2288及びその製造法
US4530835A (en) * 1983-07-08 1985-07-23 Warner-Lambert Company CL-1577 Antibiotic compounds and their production

Also Published As

Publication number Publication date
DK406086A (da) 1987-02-28
IT8621527A0 (it) 1986-08-26
IL79519A0 (en) 1986-10-31
GB2179649B (el) 1989-10-25
ZA865796B (en) 1987-04-29
SE469632B (sv) 1993-08-09
DK170671B1 (da) 1995-11-27
ATA231786A (de) 1990-12-15
IE862280L (en) 1987-02-27
IT1229176B (it) 1991-07-23
GR862160B (en) 1986-12-31
FI83422C (fi) 1991-07-10
JPH0733393B2 (ja) 1995-04-12
GB2179649A (en) 1987-03-11
KR870002269A (ko) 1987-03-30
SE8603597D0 (sv) 1986-08-26
FI83422B (fi) 1991-03-28
HUT44035A (en) 1988-01-28
SE9200428D0 (sv) 1992-02-13
ES2002728A6 (es) 1988-10-01
GB8620118D0 (en) 1986-10-01
AT392971B (de) 1991-07-25
IE59204B1 (en) 1994-01-26
HU197915B (en) 1989-06-28
NL8602165A (nl) 1987-03-16
FI863405A (fi) 1987-02-28
DE3629052A1 (de) 1987-05-07
LU86562A1 (fr) 1987-03-06
SG109692G (en) 1992-12-24
PT83261A (en) 1986-09-01
DE3629052C2 (de) 1995-09-28
DK406086D0 (da) 1986-08-26
AU604464B2 (en) 1990-12-20
AU6175186A (en) 1987-03-05
FI863405A0 (fi) 1986-08-22
FR2586686B1 (fr) 1990-02-02
JPH07233186A (ja) 1995-09-05
CH668598A5 (de) 1989-01-13
PT83261B (pt) 1989-05-12
BE905332A (fr) 1987-02-26
JPS62116589A (ja) 1987-05-28
SE9200428L (sv) 1993-08-14
CY1676A (en) 1993-10-10
SE8603597L (sv) 1987-02-28
FR2586686A1 (fr) 1987-03-06
HK793A (en) 1993-01-15
KR920010226B1 (ko) 1992-11-21

Similar Documents

Publication Publication Date Title
Kiyoto et al. A NEW ANTITUMOR ANTIBIOTIC, FR-900482 II. PRODUCTION, ISOLATION, CHARACTERIZATION AND BIOLOGICAL ACTIVITY
US4518589A (en) BBM-2478 Antibiotic complex
AU612189B2 (en) New antibiotics, benanomicins a and b and dexylosylbenanomicin b, and production and uses thereof
US4206206A (en) Antibiotics of the KA-6606 series and pharmaceutical compositions thereof
CA1307256C (en) Bbm-1675c and d antitumor antibiotics
FI59613C (fi) Foerfarande foer framstaellning av ett tumoerfoerhindrande rhodirubinkomplex och dess komponenter a och b
US4710564A (en) Anthracycline compounds
US4360458A (en) Antitumor antibacterial agents
US4921700A (en) BBM-1675c and d antitumor antibiotics
KR920001448B1 (ko) Bbm-2478 항생제 착화합물
AU4317496A (en) Novel aminooligosaccharide derivative and process for preparing the same
CZ281476B6 (cs) Polyhydroxycyklopentanové deriváty, způsob výroby a produkční mikroorganismy
US4572895A (en) Process for preparing an antibiotic complex by culturing actinomyces strain ATCC 39417
US4897470A (en) Anthracycline antibiotics DCP-1 and 2
US4451456A (en) Antitumor antibacterial agents
US4780416A (en) Microorganism for BBM 928 production
US4328307A (en) Novel antibiotics, process for preparation thereof and biologically pure culture for use therein
CA1189856A (en) Semisynthetic macrolidic antibiotics, microbiological processes for their preparation and related microorganism, novel intermediate compounds for their preparation and related pharmaceutical compositions containing them
Petráková et al. Synthesis and 13 C NMR spectra of disaccharides related to glucoxylans and xyloglucans
HU198102B (en) Process for producing anthracycline derivates and pharmaceutical copositions comprising these compounds as active ingredient
AU667753B2 (en) C-11 modified pradimicin derivatives
EP0431323A1 (en) Antitumor antibiotic BU-3983T
IE58885B1 (en) A novel anti-tumor and antimicrobial compounds, its microbiological preparation and its use as medicament

Legal Events

Date Code Title Description
MKLA Lapsed