DE3573785D1 - Gel for preventing adhesion between body tissues and process for its production - Google Patents

Gel for preventing adhesion between body tissues and process for its production

Info

Publication number
DE3573785D1
DE3573785D1 DE8585903721T DE3573785T DE3573785D1 DE 3573785 D1 DE3573785 D1 DE 3573785D1 DE 8585903721 T DE8585903721 T DE 8585903721T DE 3573785 T DE3573785 T DE 3573785T DE 3573785 D1 DE3573785 D1 DE 3573785D1
Authority
DE
Germany
Prior art keywords
gel
production
body tissues
preventing adhesion
adhesion
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8585903721T
Other languages
English (en)
Inventor
Belder Anthony De
Tomas Malson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Phadia AB
Original Assignee
Pharmacia AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia AB filed Critical Pharmacia AB
Application granted granted Critical
Publication of DE3573785D1 publication Critical patent/DE3573785D1/de
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/08Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04Macromolecular materials
    • A61L31/042Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/145Hydrogels or hydrocolloids
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0072Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Vascular Medicine (AREA)
  • Polymers & Plastics (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE8585903721T 1984-07-23 1985-07-16 Gel for preventing adhesion between body tissues and process for its production Expired DE3573785D1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE8403817A SE456346B (sv) 1984-07-23 1984-07-23 Gel for att forhindra adhesion mellan kroppsvevnader och sett for dess framstellning
PCT/SE1985/000282 WO1986000912A1 (en) 1984-07-23 1985-07-16 Gel for preventing adhesion between body tissues and process for its production

Publications (1)

Publication Number Publication Date
DE3573785D1 true DE3573785D1 (en) 1989-11-23

Family

ID=20356585

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8585903721T Expired DE3573785D1 (en) 1984-07-23 1985-07-16 Gel for preventing adhesion between body tissues and process for its production

Country Status (7)

Country Link
US (1) US4886787A (de)
EP (1) EP0190215B1 (de)
JP (1) JPH0669490B2 (de)
CA (1) CA1263647A (de)
DE (1) DE3573785D1 (de)
SE (1) SE456346B (de)
WO (1) WO1986000912A1 (de)

Families Citing this family (172)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0345370A1 (de) * 1988-06-08 1989-12-13 Malliner Laboratories Inc. Verwendung von aus Polymerhydrogel hergetellten transparenten Membranen zum Bedecken von Organen während Operationen
SE452469B (sv) * 1986-06-18 1987-11-30 Pharmacia Ab Material bestaende av en tverbunden karboxylgrupphaltig polysackarid och forfarande vid framstellning av detsamma
US5080893A (en) * 1988-05-31 1992-01-14 University Of Florida Method for preventing surgical adhesions using a dilute solution of polymer
US5017229A (en) * 1990-06-25 1991-05-21 Genzyme Corporation Water insoluble derivatives of hyaluronic acid
US6235726B1 (en) * 1987-09-18 2001-05-22 Genzyme Corporation Water insoluble derivatives of polyanionic polysaccharides
US6610669B1 (en) 1987-09-18 2003-08-26 Genzyme Corporation Water insoluble derivatives of polyanionic polysaccharides
US4937270A (en) * 1987-09-18 1990-06-26 Genzyme Corporation Water insoluble derivatives of hyaluronic acid
US5527893A (en) * 1987-09-18 1996-06-18 Genzyme Corporation Water insoluble derivatives of polyanionic polysaccharides
US6174999B1 (en) 1987-09-18 2001-01-16 Genzyme Corporation Water insoluble derivatives of polyanionic polysaccharides
US5140016A (en) * 1988-05-31 1992-08-18 University Of Florida Method and composition for preventing surgical adhesions using a dilute solution of polymer
US6010692A (en) * 1988-05-31 2000-01-04 University Of Florida Research Foundation, Inc. Method and composition for preventing surgical adhesions and tissue damage
SE8900586L (sv) * 1989-02-21 1990-08-22 Pharmacia Ab Komposition och foerfarande foer att foerhindra adhesion mellan kroppsvaevnader
US5356883A (en) * 1989-08-01 1994-10-18 Research Foundation Of State University Of N.Y. Water-insoluble derivatives of hyaluronic acid and their methods of preparation and use
US4994277A (en) * 1989-10-31 1991-02-19 Pfizer Hospital Products Group, Inc. Use of xanthan gum for preventing adhesions
US5093319A (en) * 1989-10-31 1992-03-03 Pfizer Hospital Products Group, Inc. Use of derivatives of chitin soluble in aqueous solutions for preventing adhesions
ATE116555T1 (de) * 1989-10-31 1995-01-15 Howmedica Chitinderivate enthaltende zusammensetzungen zur verhütung der adhäsion.
US5290271A (en) * 1990-05-14 1994-03-01 Jernberg Gary R Surgical implant and method for controlled release of chemotherapeutic agents
US5059123A (en) * 1990-05-14 1991-10-22 Jernberg Gary R Periodontal barrier and method for aiding periodontal tissue regeneration
US5143724A (en) * 1990-07-09 1992-09-01 Biomatrix, Inc. Biocompatible viscoelastic gel slurries, their preparation and use
GR920100122A (el) * 1991-04-05 1993-03-16 Ethicon Inc Πολυσακχαρίτες οι οποίοι περιέχουν καρβοξύλιο με σταυροειδείς δεσμούς δια την πρόληψιν της προσφύσεως.
US5605938A (en) * 1991-05-31 1997-02-25 Gliatech, Inc. Methods and compositions for inhibition of cell invasion and fibrosis using dextran sulfate
US5705178A (en) * 1991-05-31 1998-01-06 Gliatech, Inc. Methods and compositions based on inhibition of cell invasion and fibrosis by anionic polymers
JPH07503943A (ja) * 1991-10-29 1995-04-27 クローバー コンソリデイテッド,リミテッド 封入及び薬剤放出に有用な架橋性の多糖類、ポリカチオン及び脂質
JP2855307B2 (ja) * 1992-02-05 1999-02-10 生化学工業株式会社 光反応性グリコサミノグリカン、架橋グリコサミノグリカン及びそれらの製造方法
DE4209160A1 (de) * 1992-03-20 1993-09-30 Bauer Kurt Heinz Prof Dr Vernetzte Polysaccharide, Verfahren zu ihrer Herstellung und ihre Verwendung
CA2114290C (en) * 1993-01-27 2006-01-10 Nagabushanam Totakura Post-surgical anti-adhesion device
US5585361A (en) 1994-06-07 1996-12-17 Genzyme Corporation Methods for the inhibition of platelet adherence and aggregation
US6294202B1 (en) 1994-10-06 2001-09-25 Genzyme Corporation Compositions containing polyanionic polysaccharides and hydrophobic bioabsorbable polymers
US5690961A (en) * 1994-12-22 1997-11-25 Hercules Incorporated Acidic polysaccharides crosslinked with polycarboxylic acids and their uses
US5677276A (en) * 1994-12-23 1997-10-14 La Jolla Cancer Research Foundation Immobilization of peptides to hyaluronate
US5888988A (en) * 1995-05-08 1999-03-30 Chitogenics, Inc. Covalently linked N,O-carboxymethylchitosan and uses thereof
US5679658A (en) * 1995-05-08 1997-10-21 Chitogenics, Inc. N,O-carbonxymethylchitosan for prevention of surgical adhesions
US6150581A (en) * 1995-06-07 2000-11-21 United States Surgical Corporation Chitosan/alginate anti-adhesion barrier
US5807833A (en) * 1995-06-07 1998-09-15 University Of Southern California Hydroxyethyl starch and use thereof as an absorbable mechanical barrier and intracavity carrier device
EP0830381A4 (de) * 1995-06-09 2000-11-22 William N Drohan Chitinhydrogele, herstellungsverfahren und anwendung
US5612321A (en) * 1995-06-22 1997-03-18 Hercules Incorporated Antioxidant grafted polysaccharides
ATE297230T1 (de) 1995-08-29 2005-06-15 Fidia Advanced Biopolymers Srl Aus hyaluronsäurederivaten bestehenden biomaterialien zur hemmung der postoperativen adhäsionsbildung
US5897880A (en) 1995-09-29 1999-04-27 Lam Pharmaceuticals, Llc. Topical drug preparations
US6063061A (en) * 1996-08-27 2000-05-16 Fusion Medical Technologies, Inc. Fragmented polymeric compositions and methods for their use
US6066325A (en) * 1996-08-27 2000-05-23 Fusion Medical Technologies, Inc. Fragmented polymeric compositions and methods for their use
US7871637B2 (en) 1996-08-27 2011-01-18 Baxter International Inc. Dry hemostatic compositions and methods for their preparation
US20050090662A1 (en) * 1997-01-15 2005-04-28 Beavers Ellington M. Method of making free acids from polysaccharide salts
US5906997A (en) * 1997-06-17 1999-05-25 Fzio Med, Inc. Bioresorbable compositions of carboxypolysaccharide polyether intermacromolecular complexes and methods for their use in reducing surgical adhesions
US7192984B2 (en) 1997-06-17 2007-03-20 Fziomed, Inc. Compositions of polyacids and polyethers and methods for their use as dermal fillers
US6869938B1 (en) 1997-06-17 2005-03-22 Fziomed, Inc. Compositions of polyacids and polyethers and methods for their use in reducing adhesions
US6123957A (en) * 1997-07-16 2000-09-26 Jernberg; Gary R. Delivery of agents and method for regeneration of periodontal tissues
US6117979A (en) * 1997-08-18 2000-09-12 Medtronic, Inc. Process for making a bioprosthetic device and implants produced therefrom
US6818018B1 (en) 1998-08-14 2004-11-16 Incept Llc In situ polymerizable hydrogels
US6514534B1 (en) * 1998-08-14 2003-02-04 Incept Llc Methods for forming regional tissue adherent barriers and drug delivery systems
GB9826658D0 (en) * 1998-12-03 1999-01-27 Univ London Tissue repair
US7083777B1 (en) * 1999-04-02 2006-08-01 The Brigham And Women's Hospital, Inc. Immunomodulating polymers
US6645947B1 (en) * 1999-05-20 2003-11-11 Chitogenics, Inc. Adhesive N, O-carboxymethylchitosan coatings which inhibit attachment of substrate-dependent cells and proteins
EP1207828B1 (de) * 1999-07-28 2004-09-29 United States Surgical Corporation Antiadhäsionsschicht aus hyaluronsäure
US6566345B2 (en) 2000-04-28 2003-05-20 Fziomed, Inc. Polyacid/polyalkylene oxide foams and gels and methods for their delivery
US6521223B1 (en) 2000-02-14 2003-02-18 Genzyme Corporation Single phase gels for the prevention of adhesions
KR100375299B1 (ko) 2000-10-10 2003-03-10 주식회사 엘지생명과학 히알루론산의 가교결합형 아마이드 유도체와 이의 제조방법
WO2002041841A2 (en) 2000-11-21 2002-05-30 Diamond Michael P Compositions for adhesion prevention
SV2003000753A (es) 2000-12-05 2003-06-16 Brigham & Womens Hospital Uso de polisacaridos zwitterionicos para la especifica modulacion del progreso inmunologico
DE60207831D1 (de) 2001-02-22 2006-01-12 Anika Therapeutics Inc Thiol-modifizierte hyaluronan-derivate
US20020172712A1 (en) * 2001-03-19 2002-11-21 Alan Drizen Antiemetic, anti-motion sustained release drug delivery system
US7338433B2 (en) 2002-08-13 2008-03-04 Allergan, Inc. Remotely adjustable gastric banding method
US7265097B2 (en) * 2002-08-20 2007-09-04 Chitogenics, Inc. Methods of drug delivery using sulphated chitinous polymers
EP2181655B1 (de) 2002-08-28 2016-12-07 Apollo Endosurgery, Inc. Ermüdungsfeste Magenbandvorrichtung
JP2006522135A (ja) * 2003-03-31 2006-09-28 ザ ブライアム アンド ウィミンズ ホスピタル インコーポレーテッド 喘息およびアレルギーの処置のための両性イオン免疫調節剤
FR2861734B1 (fr) * 2003-04-10 2006-04-14 Corneal Ind Reticulation de polysaccharides de faible et forte masse moleculaire; preparation d'hydrogels monophasiques injectables; polysaccharides et hydrogels obtenus
US8834864B2 (en) 2003-06-05 2014-09-16 Baxter International Inc. Methods for repairing and regenerating human dura mater
US7927626B2 (en) 2003-08-07 2011-04-19 Ethicon, Inc. Process of making flowable hemostatic compositions and devices containing such compositions
MXPA06008256A (es) 2004-01-23 2007-02-20 Allergan Inc Banda gastrica ajustable de una sola pieza que se asegura de manera liberable.
EP1725193B1 (de) 2004-03-08 2009-09-30 Allergan Medical S.A. Verschlusssystem für röhrenförmige organe
AU2005223678B2 (en) 2004-03-17 2010-08-26 Genzyme Corporation Anti-adhesion spraying
EP1732635B1 (de) 2004-03-18 2011-07-27 Allergan, Inc. Vorrichtung zur volumeneinstellung intragastraler ballons
WO2006036969A2 (en) 2004-09-28 2006-04-06 Atrium Medical Corporation Formation of barrier layer
US9012506B2 (en) 2004-09-28 2015-04-21 Atrium Medical Corporation Cross-linked fatty acid-based biomaterials
US8367099B2 (en) 2004-09-28 2013-02-05 Atrium Medical Corporation Perforated fatty acid films
US9000040B2 (en) 2004-09-28 2015-04-07 Atrium Medical Corporation Cross-linked fatty acid-based biomaterials
US9801982B2 (en) 2004-09-28 2017-10-31 Atrium Medical Corporation Implantable barrier device
WO2006036967A1 (en) 2004-09-28 2006-04-06 Atrium Medical Corporation Solubilizing a drug for use in a coating
US8312836B2 (en) 2004-09-28 2012-11-20 Atrium Medical Corporation Method and apparatus for application of a fresh coating on a medical device
US8251888B2 (en) 2005-04-13 2012-08-28 Mitchell Steven Roslin Artificial gastric valve
US9427423B2 (en) 2009-03-10 2016-08-30 Atrium Medical Corporation Fatty-acid based particles
US9278161B2 (en) 2005-09-28 2016-03-08 Atrium Medical Corporation Tissue-separating fatty acid adhesion barrier
AU2006304590A1 (en) 2005-10-15 2007-04-26 Atrium Medical Corporation Hydrophobic cross-linked gels for bioabsorbable drug carrier coatings
US8043206B2 (en) 2006-01-04 2011-10-25 Allergan, Inc. Self-regulating gastric band with pressure data processing
US7798954B2 (en) 2006-01-04 2010-09-21 Allergan, Inc. Hydraulic gastric band with collapsible reservoir
WO2007092451A2 (en) 2006-02-06 2007-08-16 The Brigham And Women's Hospital, Inc. Zwitterionic polysaccharides for promotion of immune system maturation and health
US20080069857A1 (en) * 2006-04-12 2008-03-20 Yoon Yeo Compositions And Methods For Inhibiting Adhesions
TWI436793B (zh) 2006-08-02 2014-05-11 Baxter Int 快速作用之乾密封膠及其使用和製造方法
WO2008057344A2 (en) 2006-11-06 2008-05-15 Atrium Medical Corporation Coated surgical mesh
US9492596B2 (en) 2006-11-06 2016-11-15 Atrium Medical Corporation Barrier layer with underlying medical device and one or more reinforcing support structures
FR2909285A1 (fr) * 2006-12-01 2008-06-06 Anteis Sa "utilisation d'un gel anti-adhesif et anti fibrotique"
BRPI0811784A2 (pt) 2007-05-23 2011-05-10 Allergan Inc colÁgeno reticulado e uso do mesmo
US8318695B2 (en) 2007-07-30 2012-11-27 Allergan, Inc. Tunably crosslinked polysaccharide compositions
US20110077737A1 (en) * 2007-07-30 2011-03-31 Allergan, Inc. Tunably Crosslinked Polysaccharide Compositions
US20090062233A1 (en) * 2007-08-09 2009-03-05 Xin Ji Modified starch material of biocompatible hemostasis
US8697044B2 (en) 2007-10-09 2014-04-15 Allergan, Inc. Crossed-linked hyaluronic acid and collagen and uses thereof
ES2709120T3 (es) 2007-11-16 2019-04-15 Aclaris Therapeutics Inc Composiciones y métodos para tratar la púrpura
US8394782B2 (en) * 2007-11-30 2013-03-12 Allergan, Inc. Polysaccharide gel formulation having increased longevity
US8394784B2 (en) 2007-11-30 2013-03-12 Allergan, Inc. Polysaccharide gel formulation having multi-stage bioactive agent delivery
CN104888263B (zh) 2008-01-14 2018-11-30 北京环球利康科技有限公司 生物相容性止血、防粘连、促愈合、外科封闭的变性淀粉材料
EP2095832A1 (de) 2008-02-28 2009-09-02 Bayer MaterialScience AG Polyharnstoff-Systeme und deren Anwendung als postoperative Adhäsionsbarrieren, Filme und Verbundteile.
US8642831B2 (en) 2008-02-29 2014-02-04 Ferrosan Medical Devices A/S Device for promotion of hemostasis and/or wound healing
EP2280739B1 (de) * 2008-06-03 2012-07-04 Actamax Surgical Materials LLC Gewebebeschichtung zur verhinderung unerwünschter gewebeverklebungen
US8357795B2 (en) 2008-08-04 2013-01-22 Allergan, Inc. Hyaluronic acid-based gels including lidocaine
EP3184552B1 (de) 2008-09-02 2020-08-12 Tautona Group LP Stränge aus hyaluronsäure, verfahren zur herstellung davon und verwendungen davon
WO2010042493A1 (en) 2008-10-06 2010-04-15 Allergan, Inc. Mechanical gastric band with cushions
US20100305397A1 (en) * 2008-10-06 2010-12-02 Allergan Medical Sarl Hydraulic-mechanical gastric band
US20100185049A1 (en) 2008-10-22 2010-07-22 Allergan, Inc. Dome and screw valves for remotely adjustable gastric banding systems
CZ2008705A3 (cs) 2008-11-06 2010-04-14 Cpn S. R. O. Zpusob prípravy DTPA sítovaných derivátu kyseliny hyaluronové a jejich modifikace
WO2010101931A2 (en) * 2009-03-03 2010-09-10 Access Medical System Co., Ltd. Detection system and method for high sensitivity fluorescent assays
US9039783B2 (en) 2009-05-18 2015-05-26 Baxter International, Inc. Method for the improvement of mesh implant biocompatibility
CA2765117C (en) 2009-06-16 2017-07-11 Joris Hoefinghoff Hemostatic sponge
US20110038910A1 (en) 2009-08-11 2011-02-17 Atrium Medical Corporation Anti-infective antimicrobial-containing biomaterials
CN102753203A (zh) 2009-12-16 2012-10-24 巴克斯特国际公司 止血海绵
US20110172180A1 (en) 2010-01-13 2011-07-14 Allergan Industrie. Sas Heat stable hyaluronic acid compositions for dermatological use
US9114188B2 (en) 2010-01-13 2015-08-25 Allergan, Industrie, S.A.S. Stable hydrogel compositions including additives
US8758221B2 (en) 2010-02-24 2014-06-24 Apollo Endosurgery, Inc. Source reservoir with potential energy for remotely adjustable gastric banding system
US8840541B2 (en) 2010-02-25 2014-09-23 Apollo Endosurgery, Inc. Pressure sensing gastric banding system
US8586562B2 (en) 2010-03-12 2013-11-19 Allergan Industrie, Sas Fluid compositions for improving skin conditions
DK2550027T4 (da) 2010-03-22 2019-05-13 Allergan Inc Tværbundne polysaccharid- og protein-polysaccharid-hydrogeler til blødvævsforøgelse
SA111320355B1 (ar) 2010-04-07 2015-01-08 Baxter Heathcare S A إسفنجة لايقاف النزف
US9028394B2 (en) 2010-04-29 2015-05-12 Apollo Endosurgery, Inc. Self-adjusting mechanical gastric band
US9044298B2 (en) 2010-04-29 2015-06-02 Apollo Endosurgery, Inc. Self-adjusting gastric band
US20110270024A1 (en) 2010-04-29 2011-11-03 Allergan, Inc. Self-adjusting gastric band having various compliant components
US20110270025A1 (en) 2010-04-30 2011-11-03 Allergan, Inc. Remotely powered remotely adjustable gastric band system
KR101316401B1 (ko) * 2010-05-07 2013-10-10 (주)아모레퍼시픽 수불용성 겔 조성물의 고체상 제조 방법 및 그에 의해 제조된 수불용성 겔
KR101327083B1 (ko) * 2010-05-07 2013-11-07 (주)아모레퍼시픽 수불용성 겔 조성물 제조 방법 및 그에 의해 제조된 수불용성 겔
CA2801120C (en) 2010-06-01 2019-08-20 Baxter International Inc. Process for making dry and stable hemostatic compositions
WO2011151384A1 (en) 2010-06-01 2011-12-08 Baxter International Inc. Process for making dry and stable hemostatic compositions
JP5968308B2 (ja) 2010-06-01 2016-08-10 バクスター・インターナショナル・インコーポレイテッドBaxter International Incorp0Rated 乾燥した安定な止血用組成物を作成するためのプロセス
US8517915B2 (en) 2010-06-10 2013-08-27 Allergan, Inc. Remotely adjustable gastric banding system
WO2012009707A2 (en) 2010-07-16 2012-01-19 Atrium Medical Corporation Composition and methods for altering the rate of hydrolysis of cured oil-based materials
US9005605B2 (en) 2010-08-19 2015-04-14 Allergan, Inc. Compositions and soft tissue replacement methods
US8697057B2 (en) 2010-08-19 2014-04-15 Allergan, Inc. Compositions and soft tissue replacement methods
US8889123B2 (en) 2010-08-19 2014-11-18 Allergan, Inc. Compositions and soft tissue replacement methods
US8883139B2 (en) 2010-08-19 2014-11-11 Allergan Inc. Compositions and soft tissue replacement methods
US20120059216A1 (en) 2010-09-07 2012-03-08 Allergan, Inc. Remotely adjustable gastric banding system
US8961393B2 (en) 2010-11-15 2015-02-24 Apollo Endosurgery, Inc. Gastric band devices and drive systems
US9999500B2 (en) 2011-03-10 2018-06-19 University Of Florida Research Foundation, Inc. Anti thrombogenic heart valve and medical implements
US9408797B2 (en) 2011-06-03 2016-08-09 Allergan, Inc. Dermal filler compositions for fine line treatment
US20130096081A1 (en) 2011-06-03 2013-04-18 Allergan, Inc. Dermal filler compositions
EP4018999A1 (de) 2011-06-03 2022-06-29 ALLERGAN Industrie, SAS Dermale füllstoffzusammensetzungen mit antioxidantien
US9393263B2 (en) 2011-06-03 2016-07-19 Allergan, Inc. Dermal filler compositions including antioxidants
EP2731617A4 (de) 2011-07-12 2015-07-01 Brigham & Womens Hospital Lipidhaltige psa-zusammensetzungen, verfahren zu ihrer isolierung und verwendungsverfahren dafür
US9662422B2 (en) 2011-09-06 2017-05-30 Allergan, Inc. Crosslinked hyaluronic acid-collagen gels for improving tissue graft viability and soft tissue augmentation
US20130244943A1 (en) 2011-09-06 2013-09-19 Allergan, Inc. Hyaluronic acid-collagen matrices for dermal filling and volumizing applications
US20130090291A1 (en) 2011-10-11 2013-04-11 Baxter Healthcare S.A. Hemostatic compositions
ES2938568T3 (es) 2011-10-11 2023-04-12 Baxter Int Composiciones hemostaticas
UY34414A (es) 2011-10-27 2013-04-30 Baxter Int Composiciones hemostáticas
US8876694B2 (en) 2011-12-07 2014-11-04 Apollo Endosurgery, Inc. Tube connector with a guiding tip
US8961394B2 (en) 2011-12-20 2015-02-24 Apollo Endosurgery, Inc. Self-sealing fluid joint for use with a gastric band
EP2612846A1 (de) 2012-01-09 2013-07-10 Bayer MaterialScience AG Beta-Aminosäureester und deren Verwendung
IN2014DN08122A (de) 2012-03-06 2015-05-01 Ferrosan Medical Devices As
KR101240518B1 (ko) 2012-03-26 2013-03-11 주식회사 제네웰 생체 적합성 고분자를 이용한 이식용 재료
AU2013275758B2 (en) 2012-06-12 2015-03-12 Ferrosan Medical Devices A/S Dry haemostatic composition
US9867880B2 (en) 2012-06-13 2018-01-16 Atrium Medical Corporation Cured oil-hydrogel biomaterial compositions for controlled drug delivery
US20140275340A1 (en) 2013-03-15 2014-09-18 Lake Region Manufacturing, Inc. d/b/a Lake Region Medical Modified hyaluronate hydrophilic compositions, coatings and methods
US9623157B2 (en) 2013-03-15 2017-04-18 Lake Region Manufacturing, Inc. Modified hyaluronate hydrophilic compositions, coatings and methods
JP6390873B2 (ja) 2013-06-21 2018-09-19 フェッローサン メディカル ディバイス エー/エス 減圧膨張させた乾燥組成物およびそれを保持するためのシリンジ
EP3052529B1 (de) * 2013-09-30 2017-10-04 Galderma S.A. Funktionalisierung und vernetzung von hyaluronsäure
BR112016013322B1 (pt) 2013-12-11 2020-07-21 Ferrosan Medical Devices A/S métodos para preparação de uma composição seca e para reconstituir uma composição seca, composição seca, uso de uma composição seca, e, kit
US20170080120A1 (en) * 2014-05-16 2017-03-23 Ulstrast, Inc. Phase-shifting formulations
WO2016051219A1 (en) 2014-09-30 2016-04-07 Allergan Industrie, Sas Stable hydrogel compositions including additives
JP6726852B2 (ja) 2014-10-13 2020-07-22 フェッローサン メディカル ディバイス エー/エス 止血および創傷治癒に使用するための乾燥組成物
CN107206165B (zh) 2014-12-24 2020-10-23 弗罗桑医疗设备公司 用于保持并混合第一和第二物质的注射器
WO2016128783A1 (en) 2015-02-09 2016-08-18 Allergan Industrie Sas Compositions and methods for improving skin appearance
RU2717356C2 (ru) 2015-07-03 2020-03-23 Ферросан Медикал Дивайсиз А/С Шприц для удерживания вакуума в состоянии хранения
US10857177B2 (en) 2015-08-19 2020-12-08 President And Fellows Of Harvard College Lipidated PSA compositions and methods
US11491181B2 (en) 2016-07-15 2022-11-08 President And Fellows Of Harvard College Glycolipid compositions and methods of use
JP2020517760A (ja) 2017-04-05 2020-06-18 ジェレシス,エルエルシー 改良された超吸収性材料及びその製造方法
AU2019266529B2 (en) 2018-05-09 2024-05-23 Ethicon Inc. Method for preparing a haemostatic composition
RU2750000C1 (ru) * 2019-12-25 2021-06-21 Акционерное общество «Медтехнопроект» Способ получения модифицированного гиалуронана и его применение в медицине, в том числе при эндопротезировании
CN117915933A (zh) 2021-09-01 2024-04-19 上海其胜生物制剂有限公司 使用含有软骨细胞或干细胞的可注射可原位聚合胶原组合物进行软骨再生

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE169293C1 (de) * 1958-03-13 1959-11-10
US3042667A (en) * 1959-03-10 1962-07-03 Pharmacia Ab Process for producing dextran derivatives and products resulting therefrom
NL126243C (de) * 1959-06-12
SE319903B (de) * 1964-01-31 1970-01-26 Pharmacia Ab
SE452109B (sv) * 1973-01-29 1987-11-16 Pharmacia Ab Rengoringsmedel for vetskande utvertes sarytor
US4002173A (en) * 1974-07-23 1977-01-11 International Paper Company Diester crosslinked polyglucan hydrogels and reticulated sponges thereof
US4152170A (en) * 1975-06-18 1979-05-01 Sumitomo Chemical Company, Ltd. Cross-linked pullulan
GB1515963A (en) * 1975-07-15 1978-06-28 Massachusetts Inst Technology Crosslinked collagen-mucopolysaccharide composite materials
US4011392A (en) * 1975-09-02 1977-03-08 The Sherwin-Williams Company Mixed starch esters and the use thereof
DE2707308C2 (de) * 1977-02-19 1982-07-01 Hoechst Ag, 6000 Frankfurt Formkörper schwammartiger Struktur auf Basis von regenerierter Cellulose für medizinische Zwecke
JPS5844084B2 (ja) * 1977-04-01 1983-09-30 住友化学工業株式会社 イオン性プルランゲルの製造法
US4470975A (en) * 1977-10-21 1984-09-11 The Johns Hopkins University Method and composition for the elimination of water from an animal body
EP0010519A1 (de) * 1978-10-12 1980-04-30 Battelle Memorial Institute Verfahren zum Vernetzen von Carboxymethylcellulose und durch dieses Verfahren erhaltene Produkte
JPS60130601A (ja) * 1983-12-15 1985-07-12 バイオマトリツクス,インコ−ポレイテツド ヒアルロン酸水不溶性組成物の製法
US4605691A (en) * 1984-12-06 1986-08-12 Biomatrix, Inc. Cross-linked gels of hyaluronic acid and products containing such gels

Also Published As

Publication number Publication date
US4886787A (en) 1989-12-12
JPH0669490B2 (ja) 1994-09-07
WO1986000912A1 (en) 1986-02-13
CA1263647A (en) 1989-12-05
JPS61502729A (ja) 1986-11-27
SE456346B (sv) 1988-09-26
EP0190215B1 (de) 1989-10-18
SE8403817L (sv) 1986-01-24
EP0190215A1 (de) 1986-08-13
SE8403817D0 (sv) 1984-07-23

Similar Documents

Publication Publication Date Title
DE3573785D1 (en) Gel for preventing adhesion between body tissues and process for its production
AU5967086A (en) Filter body and process for its manufacture
EP0170509A3 (en) Electrode for living body
EP0171254A3 (en) Shaped chitin body
EP0166451A3 (en) Para-phenylene sulfide block copolymers; process for the production of the same and use thereof
DE3568994D1 (en) Crosslinking agents and process for their preparation
AU5021585A (en) Shaped hydrogel articles
EP0159165A3 (en) Water-absorbing laminate and production process thereof
AU3879085A (en) Contact body
EP0183283A3 (en) Single-stage hydrotreating process
DE3560934D1 (en) Therapeutical adhesive plaster and process for its manufacture
AU578720B2 (en) Use of amidochromanol in cvs disorders
EP0169114A3 (en) Human alpha-1-antitrypin derivatives and process for their preparation
AU573699B2 (en) Body support
EP0167924A3 (en) Process and device for the continuous production of alkoxypolysiloxanes
AU584596B2 (en) Continuous bioreactor and process
PT80783A (en) Process for the preparation of benzimidazols bezoxazols and benzothiazols
AU1852688A (en) Can body making apparatus
GB2166977B (en) Medical material and process for its production
AU583489B2 (en) 8alpha-acylamino-ergolines uses and production thereof
DE3569700D1 (en) Process for making body parts for cars, and body parts obtained
HUT37956A (en) Process for producing d-glycos and starch hydrolizate
GB8527679D0 (en) Preparing product for human body
AU4278685A (en) Automobile body straightening
GB8428831D0 (en) Monitoring organs of body

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: PHARMACIA & UPJOHN DIAGNOSTICS AB, UPPSALA, SE