DE3546566C2 - - Google Patents

Info

Publication number
DE3546566C2
DE3546566C2 DE3546566A DE3546566A DE3546566C2 DE 3546566 C2 DE3546566 C2 DE 3546566C2 DE 3546566 A DE3546566 A DE 3546566A DE 3546566 A DE3546566 A DE 3546566A DE 3546566 C2 DE3546566 C2 DE 3546566C2
Authority
DE
Germany
Prior art keywords
cell
light
light source
antigen
reaction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE3546566A
Other languages
German (de)
English (en)
Inventor
Akihiro Tokio/Tokyo Jp Namba
Fumio Uchino
Hitoshi Tateoka
Masahiro Hachioji Tokio/Tokyo Jp Ohno
Outaro Hino Tokio/Tokyo Jp Ando
Kouichi Fuchu Tokio/Tokyo Jp Karaki
Tatsuo Musashino Tokio/Tokyo Jp Nagasaki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Olympus Corp
Original Assignee
Olympus Optical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP18628484A external-priority patent/JPS6165143A/ja
Priority claimed from JP18628584A external-priority patent/JPS6165138A/ja
Priority claimed from JP18628284A external-priority patent/JPS6165141A/ja
Priority claimed from JP18628384A external-priority patent/JPS6165142A/ja
Priority claimed from JP18628684A external-priority patent/JPS6165144A/ja
Priority claimed from JP18725684A external-priority patent/JPS6166151A/ja
Priority claimed from JP59187255A external-priority patent/JPH0650314B2/ja
Priority claimed from JP18725484A external-priority patent/JPS6166149A/ja
Priority claimed from JP18725384A external-priority patent/JPS6166148A/ja
Priority to DE19853546681 priority Critical patent/DE3546681C2/de
Application filed by Olympus Optical Co Ltd filed Critical Olympus Optical Co Ltd
Publication of DE3546566C2 publication Critical patent/DE3546566C2/de
Application granted granted Critical
Expired legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47Scattering, i.e. diffuse reflection
    • G01N21/49Scattering, i.e. diffuse reflection within a body or fluid
    • G01N21/51Scattering, i.e. diffuse reflection within a body or fluid inside a container, e.g. in an ampoule
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/251Colorimeters; Construction thereof
    • G01N21/253Colorimeters; Construction thereof for batch operation, i.e. multisample apparatus
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/82Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a precipitate or turbidity
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01JMEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/28Investigating the spectrum
    • G01J3/44Raman spectrometry; Scattering spectrometry ; Fluorescence spectrometry
    • G01J3/4412Scattering spectrometry
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/02Investigating particle size or size distribution
    • G01N15/0205Investigating particle size or size distribution by optical means
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/02Investigating particle size or size distribution
    • G01N15/0205Investigating particle size or size distribution by optical means
    • G01N15/0211Investigating a scatter or diffraction pattern
    • G01N2015/0216Investigating a scatter or diffraction pattern from fluctuations of diffraction pattern
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03Cuvette constructions
    • G01N2021/0325Cells for testing reactions, e.g. containing reagents
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/59Transmissivity
    • G01N21/5907Densitometers
    • G01N2021/5969Scanning of a tube, a cuvette, a volume of sample
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/82Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a precipitate or turbidity
    • G01N2021/825Agglutination
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00Features of devices classified in G01N21/00
    • G01N2201/08Optical fibres; light guides
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00029Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Plasma & Fusion (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
DE3546566A 1984-09-07 1985-09-06 Expired DE3546566C2 (US20030220297A1-20031127-C00009.png)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DE19853546681 DE3546681C2 (de) 1984-09-08 1985-09-06 Automatische Analysiervorrichtung zur Messung von Antigen-Antik¦rpern-Reaktionen

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
JP18628684A JPS6165144A (ja) 1984-09-07 1984-09-07 光強度ゆらぎを用いる免疫反応測定装置
JP18628484A JPS6165143A (ja) 1984-09-07 1984-09-07 免疫反応の測定方法および装置
JP18628384A JPS6165142A (ja) 1984-09-07 1984-09-07 光強度ゆらぎを用いる免疫反応測定装置
JP18628284A JPS6165141A (ja) 1984-09-07 1984-09-07 免疫反応の測定方法および装置
JP18628584A JPS6165138A (ja) 1984-09-07 1984-09-07 光学式反応検査用セル
JP18725684A JPS6166151A (ja) 1984-09-08 1984-09-08 免疫反応の自動測定装置
JP59187255A JPH0650314B2 (ja) 1984-09-08 1984-09-08 免疫反応測定装置
JP18725484A JPS6166149A (ja) 1984-09-08 1984-09-08 免疫反応測定装置
JP18725384A JPS6166148A (ja) 1984-09-08 1984-09-08 光強度ゆらぎを用いる免疫反応測定装置

Publications (1)

Publication Number Publication Date
DE3546566C2 true DE3546566C2 (US20030220297A1-20031127-C00009.png) 1989-03-16

Family

ID=27577565

Family Applications (2)

Application Number Title Priority Date Filing Date
DE3546566A Expired DE3546566C2 (US20030220297A1-20031127-C00009.png) 1984-09-07 1985-09-06
DE19853531891 Granted DE3531891A1 (de) 1984-09-07 1985-09-06 Verfahren und vorrichtung zur messung immunologischer reaktionen

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE19853531891 Granted DE3531891A1 (de) 1984-09-07 1985-09-06 Verfahren und vorrichtung zur messung immunologischer reaktionen

Country Status (2)

Country Link
US (2) US4762413A (US20030220297A1-20031127-C00009.png)
DE (2) DE3546566C2 (US20030220297A1-20031127-C00009.png)

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US4988630A (en) * 1987-04-27 1991-01-29 Hoffmann-La Roche Inc. Multiple beam laser instrument for measuring agglutination reactions
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US5198369A (en) * 1990-04-25 1993-03-30 Canon Kabushiki Kaisha Sample measuring method using agglomeration reaction of microcarriers
US5935522A (en) * 1990-06-04 1999-08-10 University Of Utah Research Foundation On-line DNA analysis system with rapid thermal cycling
US20060013729A1 (en) * 1991-02-14 2006-01-19 Glen Carey Fluid handling apparatus for an automated analyzer
US6436349B1 (en) 1991-03-04 2002-08-20 Bayer Corporation Fluid handling apparatus for an automated analyzer
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US6498037B1 (en) * 1991-03-04 2002-12-24 Bayer Corporation Method of handling reagents in a random access protocol
US5507410A (en) * 1992-03-27 1996-04-16 Abbott Laboratories Meia cartridge feeder
US5540890A (en) * 1992-03-27 1996-07-30 Abbott Laboratories Capped-closure for a container
US5376313A (en) * 1992-03-27 1994-12-27 Abbott Laboratories Injection molding a plastic assay cuvette having low birefringence
US6190617B1 (en) 1992-03-27 2001-02-20 Abbott Laboratories Sample container segment assembly
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US5646049A (en) * 1992-03-27 1997-07-08 Abbott Laboratories Scheduling operation of an automated analytical system
US5575978A (en) * 1992-03-27 1996-11-19 Abbott Laboratories Sample container segment assembly
US5610069A (en) * 1992-03-27 1997-03-11 Abbott Laboratories Apparatus and method for washing clinical apparatus
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Also Published As

Publication number Publication date
DE3531891A1 (de) 1986-03-20
US4826319A (en) 1989-05-02
DE3531891C2 (US20030220297A1-20031127-C00009.png) 1987-10-22
US4762413A (en) 1988-08-09

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