DE3475714D1 - Griseolic acid derivatives, and their use - Google Patents

Griseolic acid derivatives, and their use

Info

Publication number
DE3475714D1
DE3475714D1 DE8484307436T DE3475714T DE3475714D1 DE 3475714 D1 DE3475714 D1 DE 3475714D1 DE 8484307436 T DE8484307436 T DE 8484307436T DE 3475714 T DE3475714 T DE 3475714T DE 3475714 D1 DE3475714 D1 DE 3475714D1
Authority
DE
Germany
Prior art keywords
acid derivatives
griseolic acid
griseolic
pde
diluents
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8484307436T
Other languages
English (en)
Inventor
Masakatsu Sankyo Chemic Kaneko
Misako Sankyo Chemical Kimura
Yoshinobu Sankyo Che Murofushi
Mitsuo Sankyo Biologi Yamazaki
Nobuyoshi Sankyo Biologi Iwata
Fumio Sankyo Fermenta Nakagawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sankyo Co Ltd
Original Assignee
Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co Ltd filed Critical Sankyo Co Ltd
Application granted granted Critical
Publication of DE3475714D1 publication Critical patent/DE3475714D1/de
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/10Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
    • A61P5/12Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH for decreasing, blocking or antagonising the activity of the posterior pituitary hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Hospice & Palliative Care (AREA)
  • Hematology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
  • Organic Insulating Materials (AREA)
  • Fats And Perfumes (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE8484307436T 1983-10-28 1984-10-29 Griseolic acid derivatives, and their use Expired DE3475714D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP58202362A JPS6094992A (ja) 1983-10-28 1983-10-28 グリゼオ−ル酸誘導体

Publications (1)

Publication Number Publication Date
DE3475714D1 true DE3475714D1 (en) 1989-01-26

Family

ID=16456245

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8484307436T Expired DE3475714D1 (en) 1983-10-28 1984-10-29 Griseolic acid derivatives, and their use

Country Status (12)

Country Link
US (1) US4634706A (de)
EP (1) EP0143557B1 (de)
JP (1) JPS6094992A (de)
KR (1) KR930000165B1 (de)
AT (1) ATE39357T1 (de)
CA (1) CA1267408A (de)
DE (1) DE3475714D1 (de)
DK (1) DK166323C (de)
ES (4) ES8604737A1 (de)
FI (1) FI81357C (de)
NO (1) NO164904C (de)
SU (4) SU1600632A3 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4783532A (en) * 1983-10-28 1988-11-08 Sankyo Company Limited Process for preparing griseolic acid derivatives
IT1196261B (it) * 1984-09-20 1988-11-16 Pierrel Spa Derivati nucleosidici e purinici 8-sostituiti
EP0318060B1 (de) * 1985-04-19 1995-10-25 Sankyo Company Limited Griseolsäurederivate, ihre Herstellung und ihre Verwendung
FI94133C (fi) * 1985-04-19 1995-07-25 Sankyo Co Menetelmä lääkeaineina käyttökelpoisten griseoliinihapon johdannaisten valmistamiseksi
JPH0631307B2 (ja) * 1985-04-27 1994-04-27 三共株式会社 グリゼオ−ル酸誘導体の製法
US5214048A (en) * 1987-05-19 1993-05-25 Nippon Kayaku Kabushiki Kaisha Oxetanocins
JPH0774229B2 (ja) * 1987-12-02 1995-08-09 三共株式会社 グリゼオール酸モノエステル誘導体
US5091431A (en) * 1988-02-08 1992-02-25 Schering Corporation Phosphodiesterase inhibitors
JPH0689020B2 (ja) * 1988-06-30 1994-11-09 三共株式会社 グリゼオール酸のモノエステル誘導体
US4971972A (en) * 1989-03-23 1990-11-20 Schering Corporation Phosphodiesterase inhibitors having an optionally substituted purine derivative portion and a benzo- or cyclopenta-furan portion
JP3645580B2 (ja) * 1993-10-22 2005-05-11 株式会社フジモト・ブラザーズ グルコースエステル誘導体を含有する脳代謝改善剤
US6291516B1 (en) * 1999-01-13 2001-09-18 Curis, Inc. Regulators of the hedgehog pathway, compositions and uses related thereto
EP1312363A1 (de) * 2001-09-28 2003-05-21 Pfizer Products Inc. Behandlungsverfahren und kits bestehend aus Wachstumshormonsekretionsförderern
US7342884B2 (en) * 2002-03-13 2008-03-11 Harmonic, Inc. Method and apparatus for one directional communications in bidirectional communications channel
WO2011081915A2 (en) * 2009-12-15 2011-07-07 Cebix Inc. Methods for treating erectile dysfunction in patients with insulin-dependent diabetes
CN113039001B (zh) * 2021-02-19 2022-10-18 安徽金禾实业股份有限公司 蔗糖-6-酯的生产设备及生产方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3862189A (en) * 1973-08-14 1975-01-21 Warner Lambert Co Aralkyl-substituted purines and pyrimidines as antianginal bronchodilator agents
GB1523865A (en) * 1974-09-02 1978-09-06 Wellcome Found Purine compunds and salts thereof
US4138562A (en) * 1977-02-09 1979-02-06 The Regents Of The University Of Minnesota Adenosine deaminase resistant antiviral purine nucleosides and method of preparation
JPS5668695A (en) * 1979-11-10 1981-06-09 Sankyo Co Ltd Enzyme inhibitor griseolic acid and its preparation
DE3028273A1 (de) * 1980-07-25 1982-02-25 Fa. Dr. Willmar Schwabe, 7500 Karlsruhe Durch purinbasen substituierte 1.4;3.6-dianhydro-hexit-nitrate
JPS60246396A (ja) * 1984-05-22 1985-12-06 Sankyo Co Ltd 酵素阻害物質ジヒドロデスオキシグリゼオ−ル酸及びその塩類

Also Published As

Publication number Publication date
CA1267408A (en) 1990-04-03
EP0143557A3 (en) 1985-07-03
FI844225L (fi) 1985-04-29
DK166323C (da) 1993-08-30
EP0143557A2 (de) 1985-06-05
DK166323B (da) 1993-04-05
FI81357C (fi) 1990-10-10
ES8604981A1 (es) 1986-02-16
ES8701193A1 (es) 1986-11-16
ES537154A0 (es) 1985-12-01
NO164904C (no) 1990-11-28
KR930000165B1 (ko) 1993-01-11
DK513384A (da) 1985-04-29
JPH0432837B2 (de) 1992-06-01
SU1468422A3 (ru) 1989-03-23
ES8700673A1 (es) 1986-10-16
ATE39357T1 (de) 1989-01-15
FI81357B (fi) 1990-06-29
SU1604158A3 (ru) 1990-10-30
NO844291L (no) 1985-04-29
JPS6094992A (ja) 1985-05-28
ES547291A0 (es) 1986-11-16
EP0143557B1 (de) 1988-12-21
NO164904B (no) 1990-08-20
FI844225A0 (fi) 1984-10-26
US4634706A (en) 1987-01-06
ES547292A0 (es) 1986-02-16
ES547347A0 (es) 1986-10-16
SU1600632A3 (ru) 1990-10-15
KR850003415A (ko) 1985-06-17
ES8604737A1 (es) 1985-12-01
DK513384D0 (da) 1984-10-26
SU1468421A3 (ru) 1989-03-23

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee