DE3429590A1 - Diastereoisomere von glycyrrhetinsaeurederivaten - Google Patents

Diastereoisomere von glycyrrhetinsaeurederivaten

Info

Publication number
DE3429590A1
DE3429590A1 DE19843429590 DE3429590A DE3429590A1 DE 3429590 A1 DE3429590 A1 DE 3429590A1 DE 19843429590 DE19843429590 DE 19843429590 DE 3429590 A DE3429590 A DE 3429590A DE 3429590 A1 DE3429590 A1 DE 3429590A1
Authority
DE
Germany
Prior art keywords
ester
coor
acetone
acid
mixture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19843429590
Other languages
German (de)
English (en)
Inventor
Graham Kenneth Maile
Lynn Kivanch London Nalbantoglu
Anthony Edward Whitton Middlesex Vanstone
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biorex Laboratories Ltd
Original Assignee
Biorex Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biorex Laboratories Ltd filed Critical Biorex Laboratories Ltd
Publication of DE3429590A1 publication Critical patent/DE3429590A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
    • C07J63/008—Expansion of ring D by one atom, e.g. D homo steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Communicable Diseases (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE19843429590 1983-08-12 1984-08-10 Diastereoisomere von glycyrrhetinsaeurederivaten Withdrawn DE3429590A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB838321715A GB8321715D0 (en) 1983-08-12 1983-08-12 Diastereoisomers of glycyrrhetinic acid derivatives

Publications (1)

Publication Number Publication Date
DE3429590A1 true DE3429590A1 (de) 1985-02-28

Family

ID=10547194

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19843429590 Withdrawn DE3429590A1 (de) 1983-08-12 1984-08-10 Diastereoisomere von glycyrrhetinsaeurederivaten

Country Status (5)

Country Link
JP (1) JPS6058942A (it)
DE (1) DE3429590A1 (it)
FR (1) FR2550537B1 (it)
GB (2) GB8321715D0 (it)
IT (1) IT1179033B (it)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5519008A (en) * 1992-09-10 1996-05-21 Glycomed Incorporated Derivatives of triterpenoid acids as inhibitors of cell-adhesion molecules ELAM-1 (E-selectin) and LECAM-1 (L-selectin)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5527890A (en) * 1993-04-16 1996-06-18 Glycomed Incorporated Derivatives of triterpenoid acids and uses thereof
GB0604899D0 (en) * 2006-03-10 2006-04-19 York Pharma Plc Derivatives of 18-glycyrrhetinic acid
CN103588849A (zh) * 2012-08-14 2014-02-19 江苏汉邦科技有限公司 一种甘草次酸的制备方法
CN104004047A (zh) * 2014-05-27 2014-08-27 普凡生生物科技(北京)有限公司 一种甘草次酸的制备方法
CN104004046A (zh) * 2014-05-27 2014-08-27 普凡生生物科技(北京)有限公司 一种乙酰甘草次酸的制备方法
CN104387439B (zh) * 2014-10-31 2017-02-01 中国农业大学 一种亚临界水解反应制备甘草酸衍生物的方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1022968A (en) * 1964-05-07 1966-03-16 Biorex Laboratories Ltd New acyl derivatives of glycyrrhetinic acid
GB1387499A (en) * 1972-09-06 1975-03-19 Biorex Laboratories Ltd Derivatives of glycyrrhetinic acid

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5519008A (en) * 1992-09-10 1996-05-21 Glycomed Incorporated Derivatives of triterpenoid acids as inhibitors of cell-adhesion molecules ELAM-1 (E-selectin) and LECAM-1 (L-selectin)

Also Published As

Publication number Publication date
GB2144746A (en) 1985-03-13
GB8418700D0 (en) 1984-08-30
IT8467795A1 (it) 1986-02-08
JPS6058942A (ja) 1985-04-05
FR2550537A1 (fr) 1985-02-15
IT8467795A0 (it) 1984-08-08
IT1179033B (it) 1987-09-16
FR2550537B1 (fr) 1989-03-10
GB2144746B (en) 1986-11-05
GB8321715D0 (en) 1983-09-14

Similar Documents

Publication Publication Date Title
DE3429590A1 (de) Diastereoisomere von glycyrrhetinsaeurederivaten
DE1804691C3 (de) Taurocholensäurederivate
DE3106815A1 (de) "chemische verbindungen, verfahren zu ihrer herstellung und ihre verwendung als antigene oder immunadsorbentien"
DE2167180C3 (de) Methyl-7-desoxy-7(S)-methoxy-α-thiolincosaminid und Verfahren zu dessen Herstellung
DE2603596C2 (de) Glycyrrhetinsäurederivate, Verfahren zu ihrer Herstellung und sie enthaltende Arzneimittel
DE2404946C3 (de) Verfahren zur Herstellung von 7alpha-Acylthio-Steroidspirolactonen
DE69206321T2 (de) Ursane Derivate, ihre Herstellung und die enthaltende pharmazeutische Zusammensetzung.
CH631722A5 (de) Verfahren zur herstellung hochreiner, kristalliner chenodesoxycholsaeure.
DE2043048C3 (de) d-2-(Methylmercapto-2-naphthyl> propanal, Verfahren zu dessen Herstellung und dieses enthaltende Heilmittel
DE2520488A1 (de) Verfahren zur gewinnung reiner 3alpha,7alpha-dihydroxy-5beta-cholansaeure
DE1205094B (de) Verfahren zur Herstellung von 17alpha-Aminosteroiden der Androstenreihe
AT274248B (de) Verfahren zur Herstellung neuer Derivate von Bufadienolidglykosiden
DE2711081A1 (de) Tritiumderivate der glycyrrhetinsaeure und verfahren zu ihrer herstellung
AT241707B (de) Verfahren zur Herstellung neuer Oestradiolderivate
AT240540B (de) Verfahren zur Herstellung von 4-Chlor-Δ<4>-3-ketosteroidverbindungen
AT228949B (de) Verfahren zur Herstellung neuer therapeutisch wirksamer Derivate des 4-Hydroxy-17α-methyl-testosterons
AT160853B (de) Verfahren zur Herstellung von ungesättigten und gesättigten in 21-Stellung substituierten Derivaten des Pregnanol-(3)-ons-(20).
DE1963597C3 (de) Neue Neriifolin-Derivate, Verfahren zur Herstellung derselben sowie diese enthaltende Arzneimittel
DE2302671A1 (de) 5-acylpyrrole, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
AT248622B (de) Verfahren zur Herstellung neuer 2-Cyano-3-oxo-steroide
AT241706B (de) Verfahren zur Herstellung von 18, 20-Laktonen der Pregnanreihe
US3076000A (en) Esters of bile acid degradation products and a process for preparing same
AT123413B (de) Verfahren zur Darstellung von Acylderivaten des k-Strophantidins.
DE2319873A1 (de) 16-o-alkylderivate von gitoxigenindigitoxosiden und verfahren zu ihrer herstellung
DE2535348A1 (de) Verfahren zur herstellung und verwendung von stabilisierten gefaessaktiven verbindungen

Legal Events

Date Code Title Description
8139 Disposal/non-payment of the annual fee