DE3106460A1 - 2(1h)-pyridinon-derivate, ihre herstellung und sie enthaltende pharmazeutische zubereitungen - Google Patents

2(1h)-pyridinon-derivate, ihre herstellung und sie enthaltende pharmazeutische zubereitungen

Info

Publication number
DE3106460A1
DE3106460A1 DE19813106460 DE3106460A DE3106460A1 DE 3106460 A1 DE3106460 A1 DE 3106460A1 DE 19813106460 DE19813106460 DE 19813106460 DE 3106460 A DE3106460 A DE 3106460A DE 3106460 A1 DE3106460 A1 DE 3106460A1
Authority
DE
Germany
Prior art keywords
compounds
formula
phenyl
carbon atoms
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19813106460
Other languages
German (de)
English (en)
Inventor
Gerhard 4142 Münchenstein Bormann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Sandoz Patent GmbH
Original Assignee
Sandoz AG
Sandoz Patent GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG, Sandoz Patent GmbH filed Critical Sandoz AG
Publication of DE3106460A1 publication Critical patent/DE3106460A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/73—Unsubstituted amino or imino radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C07D213/82—Amides; Imides in position 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE19813106460 1980-03-03 1981-02-21 2(1h)-pyridinon-derivate, ihre herstellung und sie enthaltende pharmazeutische zubereitungen Withdrawn DE3106460A1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CH166980 1980-03-03
CH166880 1980-03-03
CH571780 1980-07-25
CH794780 1980-10-24

Publications (1)

Publication Number Publication Date
DE3106460A1 true DE3106460A1 (de) 1982-01-28

Family

ID=27428258

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19813106460 Withdrawn DE3106460A1 (de) 1980-03-03 1981-02-21 2(1h)-pyridinon-derivate, ihre herstellung und sie enthaltende pharmazeutische zubereitungen

Country Status (16)

Country Link
CA (1) CA1183533A (fr)
CH (1) CH652395A5 (fr)
DE (1) DE3106460A1 (fr)
DK (1) DK94481A (fr)
ES (1) ES499971A0 (fr)
FI (1) FI810558L (fr)
FR (1) FR2477148A1 (fr)
GB (1) GB2070606B (fr)
IL (1) IL62246A (fr)
IT (1) IT1142458B (fr)
NL (1) NL8100964A (fr)
NZ (1) NZ196385A (fr)
PT (1) PT72596B (fr)
SE (1) SE8101336L (fr)
WO (1) WO1981002575A1 (fr)
YU (1) YU51581A (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0154190A1 (fr) * 1984-02-22 1985-09-11 MERCK PATENT GmbH Pyridones
EP0200024A2 (fr) 1985-04-30 1986-11-05 ARZNEIMITTELWERK DRESDEN GmbH Pyridine-3-nitriles, leur procédé de préparation et leur utilisation pharmaceutique

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL65278A0 (en) * 1981-03-30 1982-05-31 Sterling Drug Inc 3-amino-5-(substituted)-2(1h)-pyridinones and corresponding 3-cyano compounds,their preparation and pharmaceutical compositions containing them
US4515797A (en) * 1981-09-08 1985-05-07 Sterling Drug Inc. 3-Amino-5-(hydroxy- and/or aminophenyl)-6-(lower-alkyl)-2(1H)-pyridinones and cardiotonic use thereof
US4465686A (en) * 1981-09-08 1984-08-14 Sterling Drug Inc. 5-(Hydroxy- and/or amino-phenyl)-6-(lower-alkyl)-2-(1H)-pyridinones, their cardiotonic use and preparation
US4514400A (en) * 1981-10-26 1985-04-30 William H. Rorer, Inc. Cardiotonic 5-heteroaryl-pyridone
US4593028A (en) * 1981-10-26 1986-06-03 William H. Rorer, Inc. 5-hetero aryl-substituted-2-pyridones useful as cardiotonic agents for treatment of congestive heart failure
US4539321A (en) * 1981-10-26 1985-09-03 William H. Rorer, Inc. 5-Diaza-aryl-3-substituted pyridone compounds
US4432979A (en) * 1981-10-26 1984-02-21 William H. Rorer, Inc. Pyridone compounds
AT384021B (de) * 1982-05-18 1987-09-25 Sandoz Ag Verfahren zur herstellung neuer 2(1h)-pyridinon- derivate und ihrer salze
FR2527206B1 (fr) * 1982-05-18 1986-12-05 Sandoz Sa Nouveaux derives de la 2(1h)-pyridinone, leur preparation et leur utilisation comme medicaments
FR2529891A1 (fr) * 1982-07-12 1984-01-13 Nativelle Sa Ets Derives du pyridyl-3 alcoxy-5 pyrazole, procede de preparation et application en therapeutique
IT8367883A0 (it) * 1982-08-23 1983-08-22 Rorer Int Overseas Composti cardiotonici del 2 piridone 5 biciclico eteroaril sostituito e relative composizioni farmaceutiche
IL69407A (en) * 1982-08-23 1987-10-20 Warner Lambert Co 2(1h)-pyridinones,their preparation and pharmaceutical compositions containing them
US4503061A (en) * 1983-07-22 1985-03-05 Warner-Lambert Company Substituted phenyl-pyridinones as cardiotonic agents
US4517192A (en) * 1983-01-31 1985-05-14 Sterling Drug Inc. 6-Alkyl-5-[4-(alkylsulfinyl or alkylsulfonyl)phenyl]-2(1H)-pyridinones and their use as cardiatonics
ES8600746A1 (es) * 1983-04-20 1985-10-16 Quimicos Y Farmaceuticos Abel Un nuevo procedimiento para la preparacion de 5-azinil-1,2-dihidroazin-2-onas.
US4568751A (en) * 1983-04-29 1986-02-04 Merrell Dow Pharmaceuticals Inc. 5-Acyl-2-(1H)-pyridinones
US4666913A (en) * 1985-11-22 1987-05-19 William H. Rorer, Inc. Hydroxy and aminothiazolyl-benzodiazinone compounds, cardiotonic compositions including the same, and their uses
US4785005A (en) * 1986-06-25 1988-11-15 Rorer Pharmaceutical Corporation 6-(6-alkylpyridone)-carbostyril compounds and their cardiotonic uses
US5254571A (en) * 1988-04-21 1993-10-19 Smith Kline & French Laboratories Ltd. Chemical compounds
GB8809481D0 (en) * 1988-04-21 1988-05-25 Smith Kline French Lab Chemical compounds
GB8923131D0 (en) * 1989-10-13 1989-11-29 Smith Kline French Lab Chemical compounds

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3355278A (en) * 1961-03-13 1967-11-28 Hooker Chemical Corp Herbicidal composition and method
NL6816241A (fr) * 1967-12-01 1969-06-03
FR2050940A5 (fr) * 1969-06-30 1971-04-02 Rhone Poulenc Sa
US3666765A (en) * 1969-10-27 1972-05-30 Union Carbide Corp Synthesis of 2-pyridones and derivatives thereof
US3721676A (en) * 1969-11-12 1973-03-20 Merck & Co Inc Certain 3-amino-2(1h)pyridones
BE758759A (fr) * 1969-11-12 1971-05-10 Merck & Co Inc Pyridones anti-inflammatoires
US4038396A (en) * 1975-02-24 1977-07-26 Merck & Co., Inc. Anti-inflammatory oxazole[4,5-b]pyridines
US4072746A (en) * 1975-10-14 1978-02-07 Sterling Drug Inc. 3-Amino-5-(pyridinyl)-2(1H)-pyridinones

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0154190A1 (fr) * 1984-02-22 1985-09-11 MERCK PATENT GmbH Pyridones
EP0200024A2 (fr) 1985-04-30 1986-11-05 ARZNEIMITTELWERK DRESDEN GmbH Pyridine-3-nitriles, leur procédé de préparation et leur utilisation pharmaceutique

Also Published As

Publication number Publication date
WO1981002575A1 (fr) 1981-09-17
CA1183533A (fr) 1985-03-05
FI810558L (fi) 1981-09-04
ES8301469A1 (es) 1982-12-01
SE8101336L (sv) 1981-09-04
DK94481A (da) 1981-09-04
YU51581A (en) 1983-12-31
IT8147920A0 (it) 1981-03-02
IT1142458B (it) 1986-10-08
CH652395A5 (de) 1985-11-15
IL62246A0 (en) 1981-05-20
IL62246A (en) 1984-09-30
FR2477148A1 (fr) 1981-09-04
ES499971A0 (es) 1982-12-01
FR2477148B1 (fr) 1983-09-02
GB2070606A (en) 1981-09-09
PT72596B (en) 1982-07-13
NL8100964A (nl) 1981-10-01
PT72596A (en) 1981-04-01
GB2070606B (en) 1984-02-29
NZ196385A (en) 1983-12-16

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Legal Events

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8139 Disposal/non-payment of the annual fee